메뉴 건너뛰기




Volumn 10, Issue 2, 2012, Pages 160-163

Clinical challenges in a patient with dabigatran-induced fatal hemorrhage

Author keywords

bleeding; dabigatran; direct thrombin inhibitor; prothrombin complex concentrate; recombinant factor VIIa

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BICARBONATE; BLOOD CLOTTING FACTOR 9 COMPLEX; CARBON DIOXIDE; CREATININE; DABIGATRAN; HEMOGLOBIN; OXYGENASE; VITAMIN K GROUP;

EID: 84859549864     PISSN: 15435946     EISSN: 18767761     Source Type: Journal    
DOI: 10.1016/j.amjopharm.2012.02.004     Document Type: Article
Times cited : (65)

References (17)
  • 1
    • 79960955075 scopus 로고    scopus 로고
    • The use of dabigatran in elderly patients
    • Legrand M, Mateo J, Aribaud A, et al. The use of dabigatran in elderly patients. Arch Intern Med. 2011;171: 1285-88.
    • (2011) Arch Intern Med , vol.171 , pp. 1285-1288
    • Legrand, M.1    Mateo, J.2    Aribaud, A.3
  • 2
    • 79954534386 scopus 로고    scopus 로고
    • Laboratory assessment of new anticoagulants
    • Samama MM, Guinet C. Laboratory assessment of new anticoagulants. Clin Chem Lab Med. 2011;49:761-772.
    • (2011) Clin Chem Lab Med , vol.49 , pp. 761-772
    • Samama, M.M.1    Guinet, C.2
  • 3
    • 77953168824 scopus 로고    scopus 로고
    • Dabigatran etexilate, a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
    • Van Ryn J, Stangier J, Haertter S, et al. Dabigatran etexilate, a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity. Thromb Haemost. 2010;103:1116-1127.
    • (2010) Thromb Haemost , vol.103 , pp. 1116-1127
    • Van Ryn, J.1    Stangier, J.2    Haertter, S.3
  • 4
    • 0035251820 scopus 로고    scopus 로고
    • Effect of activated prothrombin complex concentrate or recombinant factor VIIa on the bleeding time and thrombus formation during anticoagulation with a direct thrombin inhibitor
    • DOI 10.1016/S0049-3848(00)00397-2, PII S0049384800003972
    • Elg M, Carlsson S, Gustafsson D. Effect of activated prothrombin complex concentrate or recombinant factor VIIa on the bleeding time and thrombus formation during anticoagulation with a direct thrombin inhibitor. Thromb Res. 2001;101:145-157. (Pubitemid 32176020)
    • (2001) Thrombosis Research , vol.101 , Issue.3 , pp. 145-157
    • Elg, M.1    Carlsson, S.2    Gustafsson, D.3
  • 5
    • 0035251738 scopus 로고    scopus 로고
    • Effects of agents, used to treat bleeding disorders, on bleeding time prolonged by a very high dose of a direct thrombin inhibitor in anesthesized rats and rabbits
    • DOI 10.1016/S0049-3848(00)00398-4, PII S0049384800003984
    • Elg M, Carlsson S, Gustafsson D. Effect of agents, used to treat bleeding disorders, on bleeding time prolonged by a very high dose of a direct thrombin inhibitor in anesthetized rats and rabbits. Thromb Res. 2001;101:159-170. (Pubitemid 32176021)
    • (2001) Thrombosis Research , vol.101 , Issue.3 , pp. 159-170
    • Elg, M.1    Carlsson, S.2    Gustafsson, D.3
  • 6
    • 33751275469 scopus 로고    scopus 로고
    • Hemostatic effect of activated factor VII without promotion of thrombus growth in melagatran-anticoagulated primates
    • DOI 10.1016/j.thromres.2005.12.002, PII S0049384805004822
    • Gruber A, Carlsson S, Kotze HF, et al. Hemostatic effect of activated factor VII without promotion of thrombus growth in melagatran-anticoagulated primates. Thromb Res. 2007;119:121-127. (Pubitemid 44794355)
    • (2007) Thrombosis Research , vol.119 , Issue.1 , pp. 121-127
    • Gruber, A.1    Carlsson, S.2    Kotze, H.F.3    Marzec, U.4    Sarich, T.C.5    Hanson, S.R.6
  • 7
    • 79952004141 scopus 로고    scopus 로고
    • Effects on fibrin network porosity of anticoagulants with different modes of action and reversal by activated coagulation factor concentrate
    • Blombäck M, He S, Bark N, et al. Effects on fibrin network porosity of anticoagulants with different modes of action and reversal by activated coagulation factor concentrate. Br J Haematol. 2011;152:758-765.
    • (2011) Br J Haematol , vol.152 , pp. 758-765
    • Blombäck, M.1    He, S.2    Bark, N.3
  • 9
    • 33749831754 scopus 로고    scopus 로고
    • A direct thrombin inhibitor studied by dynamic whole blood clot formation. Haemostatic response to ex-vivo addition of recombinant factor VIIa or activated prothrombin complex concentrate
    • DOI 10.1160/TH06-04-0205
    • Sørensen B, Ingerslev J. A direct thrombin inhibitor studied by dynamic whole blood clot formation: haemostatic response to ex-vivo addition of recombinant factor VIIa or activated prothrombin complex concentrate. Thromb Haemost. 2006;96:446-453. (Pubitemid 44560678)
    • (2006) Thrombosis and Haemostasis , vol.96 , Issue.4 , pp. 446-453
    • Sorensen, B.1    Ingerslev, J.2
  • 10
    • 80053571188 scopus 로고    scopus 로고
    • Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate
    • Eerenberg ES, Kamphuisen PW, Sijpkens MK, et al. Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate. Circulation. 2011;124:1573- 1579.
    • (2011) Circulation , vol.124 , pp. 1573-1579
    • Eerenberg, E.S.1    Kamphuisen, P.W.2    Sijpkens, M.K.3
  • 11
    • 84859549307 scopus 로고    scopus 로고
    • Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; August
    • Product information. Dabigatran (Pradaxa). Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; August 2011.
    • (2011) Product Information. Dabigatran (Pradaxa)
  • 12
    • 79851482951 scopus 로고    scopus 로고
    • Effects of the oral, direct thrombin inhibitor dabigatran on five common coagulation assays
    • Lindahl TL, Baghaei F, Blixter IF, et al. Effects of the oral, direct thrombin inhibitor dabigatran on five common coagulation assays. Thromb Haemost. 2011;105: 371-378.
    • (2011) Thromb Haemost , vol.105 , pp. 371-378
    • Lindahl, T.L.1    Baghaei, F.2    Blixter, I.F.3
  • 13
    • 79960798870 scopus 로고    scopus 로고
    • Potential inaccuracy of point-of-care INR in dabigatran-treated patients
    • Baruch L, Sherman O. Potential inaccuracy of point-of-care INR in dabigatran-treated patients. Ann Pharmacother. 2011;45:e40.
    • (2011) Ann Pharmacother , vol.45
    • Baruch, L.1    Sherman, O.2
  • 14
    • 80052030287 scopus 로고    scopus 로고
    • Dabigatran falsely elevates point of care international normalized ratio results
    • DeRemer CE, Gujral JS, Thornton JW, et al. Dabigatran falsely elevates point of care international normalized ratio results. Am J Med. 2011;124:e5-e6.
    • (2011) Am J Med , vol.124
    • DeRemer, C.E.1    Gujral, J.S.2    Thornton, J.W.3
  • 15
    • 77949421739 scopus 로고    scopus 로고
    • Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: An open-label, parallelgroup, single-centre study
    • Stangier J, Rathgen K, Stähle H, et al. Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: an open-label, parallelgroup, single-centre study. Clin Pharmacokinet. 2010; 49:259-268.
    • (2010) Clin Pharmacokinet , vol.49 , pp. 259-268
    • Stangier, J.1    Rathgen, K.2    Stähle, H.3
  • 16
    • 79960936716 scopus 로고    scopus 로고
    • Ridgefield, Conn: Boehringer Ingelheim Pharmaceuticals, Inc.; August 27, Accessed November 3, 2011
    • Pradaxa (dabigatran etexilate): Advisory Committee briefing document. Ridgefield, Conn: Boehringer Ingelheim Pharmaceuticals, Inc.; August 27, 2010. http://www.fda.gov/ downloads/advisorycommittees/committeesmeetingmate rials/drugs/cardiovascularandrenaldrugsadvisory committe/ucm226009.pdf. Accessed November 3, 2011.
    • (2010) Pradaxa (Dabigatran Etexilate): Advisory Committee Briefing Document
  • 17
    • 84859591121 scopus 로고    scopus 로고
    • 30. Accessed December 20, 2011
    • US Food and Drug Administration. Dabigatran etexilate. Advisory Committee briefing document. http://www.fda. gov/downloads/advisorycommittees/ committeesmeeting materials/drugs/cardiovascularandrenaldrugsadvisory committee/ucm226009.pdf 30. Accessed December 20, 2011.
    • Dabigatran Etexilate. Advisory Committee Briefing Document


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.