메뉴 건너뛰기




Volumn 20, Issue 24, 2014, Pages 7718-7729

Nonalcoholic fatty liver disease: Updates in noninvasive diagnosis and correlation with cardiovascular disease

Author keywords

Cardiovascular disease; Image assessment; Laboratory biochemistry; Nonalcoholic fatty liver disease; Noninvasive diagnosis

Indexed keywords

ADIPONECTIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; C REACTIVE PROTEIN; COLLAGEN TYPE 4; CYTOKERATIN 18; FERRITIN; GAMMA GLUTAMYLTRANSFERASE; INTERLEUKIN 6; PROCOLLAGEN TYPE 3 AMINOPROPEPTIDE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; AUTACOID;

EID: 84903123873     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v20.i24.7718     Document Type: Article
Times cited : (25)

References (91)
  • 1
    • 0033038672 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity
    • [PMID: 10348825 DOI: 10.1016/S0016-5085]
    • Matteoni CA, Younossi ZM, Gramlich T, Boparai N, Liu YC, McCullough AJ. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 1999; 116: 1413-1419 [PMID: 10348825 DOI: 10.1016/S0016-5085]
    • (1999) Gastroenterology , vol.116 , pp. 1413-1419
    • Matteoni, C.A.1    Younossi, Z.M.2    Gramlich, T.3    Boparai, N.4    Liu, Y.C.5    McCullough, A.J.6
  • 2
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: From steatosis to cirrhosis
    • [PMID: 16447287 DOI: 10.1002/hep.20973]
    • Farrell GC, Larter CZ. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 2006; 43: S99-S112 [PMID: 16447287 DOI: 10.1002/hep.20973]
    • (2006) Hepatology , vol.43
    • Farrell, G.C.1    Larter, C.Z.2
  • 3
    • 0038805259 scopus 로고    scopus 로고
    • The prevalence and etiology of elevated aminotransferase levels in the United States
    • [PMID: 12809815 DOI: 10.1016/S0002-9270(03)00265-X]
    • Clark JM, Brancati FL, Diehl AM. The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol 2003; 98: 960-967 [PMID: 12809815 DOI: 10.1016/S0002-9270(03)00265-X]
    • (2003) Am J Gastroenterol , vol.98 , pp. 960-967
    • Clark, J.M.1    Brancati, F.L.2    Diehl, A.M.3
  • 4
    • 84880245463 scopus 로고    scopus 로고
    • Prevalence of nonalcoholic fatty liver disease in the United States: The Third National Health and Nutrition Examination Survey, 1988-1994
    • [PMID: 23703888 DOI: 10.1093/aje/kws448]
    • Lazo M, Hernaez R, Eberhardt MS, Bonekamp S, Kamel I, Guallar E, Koteish A, Brancati FL, Clark JM. Prevalence of nonalcoholic fatty liver disease in the United States: the Third National Health and Nutrition Examination Survey, 1988-1994. Am J Epidemiol 2013; 178: 38-45 [PMID: 23703888 DOI: 10.1093/aje/kws448]
    • (2013) Am J Epidemiol , vol.178 , pp. 38-45
    • Lazo, M.1    Hernaez, R.2    Eberhardt, M.S.3    Bonekamp, S.4    Kamel, I.5    Guallar, E.6    Koteish, A.7    Brancati, F.L.8    Clark, J.M.9
  • 5
    • 0037221394 scopus 로고    scopus 로고
    • Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States
    • [PMID: 12512031 DOI: 10.1053/gast.2003.50004]
    • Ruhl CE, Everhart JE. Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States. Gastroenterology 2003; 124: 71-79 [PMID: 12512031 DOI: 10.1053/gast.2003.50004]
    • (2003) Gastroenterology , vol.124 , pp. 71-79
    • Ruhl, C.E.1    Everhart, J.E.2
  • 6
    • 34250332701 scopus 로고    scopus 로고
    • What are the risk factors and settings for non-alcoholic fatty liver disease in Asia-Pacific?
    • [PMID: 17498218 DOI: 10.1111/j.1440-1746.2007.04952., x]
    • Fan JG, Saibara T, Chitturi S, Kim BI, Sung JJ, Chutaputti A. What are the risk factors and settings for non-alcoholic fatty liver disease in Asia-Pacific? J Gastroenterol Hepatol 2007; 22: 794-800 [PMID: 17498218 DOI: 10.1111/j.1440-1746.2007.04952. x]
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. 794-800
    • Fan, J.G.1    Saibara, T.2    Chitturi, S.3    Kim, B.I.4    Sung, J.J.5    Chutaputti, A.6
  • 7
    • 84877585029 scopus 로고    scopus 로고
    • NAFLD in Asia--as common and important as in the West
    • [PMID: 23458891 DOI: 10.1038/ nrgastro.2013.34]
    • Farrell GC, Wong VW, Chitturi S. NAFLD in Asia--as common and important as in the West. Nat Rev Gastroenterol Hepatol 2013; 10: 307-318 [PMID: 23458891 DOI: 10.1038/ nrgastro.2013.34]
    • (2013) Nat Rev Gastroenterol Hepatol , vol.10 , pp. 307-318
    • Farrell, G.C.1    Wong, V.W.2    Chitturi, S.3
  • 8
    • 0344393668 scopus 로고    scopus 로고
    • Increase in the prevalence of fatty liver in Japan over the past 12 years: Analysis of clinical background
    • [PMID: 14614602 DOI: 10.1007/ s00535-003-1178-8]
    • Kojima S, Watanabe N, Numata M, Ogawa T, Matsuzaki S. Increase in the prevalence of fatty liver in Japan over the past 12 years: analysis of clinical background. J Gastroenterol 2003; 38: 954-961 [PMID: 14614602 DOI: 10.1007/ s00535-003-1178-8]
    • (2003) J Gastroenterol , vol.38 , pp. 954-961
    • Kojima, S.1    Watanabe, N.2    Numata, M.3    Ogawa, T.4    Matsuzaki, S.5
  • 10
    • 22344453700 scopus 로고    scopus 로고
    • Natural history of NAFLD: Remarkably benign in the absence of cirrhosis
    • [PMID: 16012969 DOI: 10.1053/j.gastro.2005.05.041]
    • Day CP. Natural history of NAFLD: remarkably benign in the absence of cirrhosis. Gastroenterology 2005; 129: 375-378 [PMID: 16012969 DOI: 10.1053/j.gastro.2005.05.041]
    • (2005) Gastroenterology , vol.129 , pp. 375-378
    • Day, C.P.1
  • 11
    • 33644865032 scopus 로고    scopus 로고
    • Are we overestimating the risks of NASH?
    • author reply 1016-1017, [PMID: 16530550 DOI: 10.1053/j.gastro.2006.01.078]
    • Thomas V, Harish K. Are we overestimating the risks of NASH? Gastroenterology 2006; 130: 1015-106; author reply 1016-1017 [PMID: 16530550 DOI: 10.1053/j.gastro.2006.01.078]
    • (2006) Gastroenterology , vol.130 , pp. 1015-1061
    • Thomas, V.1    Harish, K.2
  • 12
    • 37549047145 scopus 로고    scopus 로고
    • Fatty liver: A novel component of the metabolic syndrome
    • [PMID: 17690317 DOI: 10.1161/AT, VBAHA.107.147538]
    • Kotronen A, Yki-Järvinen H. Fatty liver: a novel component of the metabolic syndrome. Arterioscler Thromb Vasc Biol 2008; 28: 27-38 [PMID: 17690317 DOI: 10.1161/ATVBAHA.107.147538]
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 27-38
    • Kotronen, A.1    Yki-Järvinen, H.2
  • 13
    • 4444382796 scopus 로고    scopus 로고
    • Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study
    • [PMID: 15364185 DOI: 10.1016/S0140-6736(04)17018-9]
    • Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F, McQueen M, Budaj A, Pais P, Varigos J, Lisheng L. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet 2004; 364: 937-952 [PMID: 15364185 DOI: 10.1016/S0140-6736(04)17018-9]
    • (2004) Lancet , vol.364 , pp. 937-952
    • Yusuf, S.1    Hawken, S.2    Ounpuu, S.3    Dans, T.4    Avezum, A.5    Lanas, F.6    McQueen, M.7    Budaj, A.8    Pais, P.9    Varigos, J.10    Lisheng, L.11
  • 14
    • 77957375969 scopus 로고    scopus 로고
    • Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease
    • [PMID: 20879883 DOI: 10.1056/ NEJMra0912063]
    • Targher G, Day CP, Bonora E. Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease. N Engl J Med 2010; 363: 1341-1350 [PMID: 20879883 DOI: 10.1056/ NEJMra0912063]
    • (2010) N Engl J Med , vol.363 , pp. 1341-1350
    • Targher, G.1    Day, C.P.2    Bonora, E.3
  • 15
    • 22344452893 scopus 로고    scopus 로고
    • The natural history of nonalcoholic fatty liver disease: A population-based cohort study
    • [PMID: 16012941 DOI: 10.1053/ j.gastro]
    • Adams LA, Lymp JF, St Sauver J, Sanderson SO, Lindor KD, Feldstein A, Angulo P. The natural history of nonalcoholic fatty liver disease: a population-based cohort study. Gastroenterology 2005; 129: 113-121 [PMID: 16012941 DOI: 10.1053/ j.gastro]
    • (2005) Gastroenterology , vol.129 , pp. 113-121
    • Adams, L.A.1    Lymp, J.F.2    Sauver, J.S.3    Sanderson, S.O.4    Lindor, K.D.5    Feldstein, A.6    Angulo, P.7
  • 17
    • 84984562986 scopus 로고    scopus 로고
    • How common is non-alcoholic fatty liver disease in the Asia-Pacific region and are there local differences?
    • [PMID: 17565631 DOI: 10.1111/j.1440-1746.2007.05042.x]
    • Amarapurkar DN, Hashimoto E, Lesmana LA, Sollano JD, Chen PJ, Goh KL. How common is non-alcoholic fatty liver disease in the Asia-Pacific region and are there local differences? J Gastroenterol Hepatol 2007; 22: 788-793 [PMID: 17565631 DOI: 10.1111/j.1440-1746.2007.05042.x]
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. 788-793
    • Amarapurkar, D.N.1    Hashimoto, E.2    Lesmana, L.A.3    Sollano, J.D.4    Chen, P.J.5    Goh, K.L.6
  • 18
  • 20
    • 84857046691 scopus 로고    scopus 로고
    • Prevalence of non-alcoholic fatty liver disease and advanced fibrosis in Hong Kong Chinese: A population study using proton-magnetic resonance spectroscopy and transient elastography
    • [PMID: 21846782 DOI: 10.1136/gutjnl-2011-300342]
    • Wong VW, Chu WC, Wong GL, Chan RS, Chim AM, Ong A, Yeung DK, Yiu KK, Chu SH, Woo J, Chan FK, Chan HL. Prevalence of non-alcoholic fatty liver disease and advanced fibrosis in Hong Kong Chinese: a population study using proton-magnetic resonance spectroscopy and transient elastography. Gut 2012; 61: 409-415 [PMID: 21846782 DOI: 10.1136/gutjnl-2011-300342]
    • (2012) Gut , vol.61 , pp. 409-415
    • Wong, V.W.1    Chu, W.C.2    Wong, G.L.3    Chan, R.S.4    Chim, A.M.5    Ong, A.6    Yeung, D.K.7    Yiu, K.K.8    Chu, S.H.9    Woo, J.10    Chan, F.K.11    Chan, H.L.12
  • 21
    • 51349083814 scopus 로고    scopus 로고
    • Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: A role for insulin resistance and diabetes
    • [PMID: 18752331 DOI: 10.1002/hep.22429]
    • Fracanzani AL, Valenti L, Bugianesi E, Andreoletti M, Colli A, Vanni E, Bertelli C, Fatta E, Bignamini D, Marchesini G, Fargion S. Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: a role for insulin resistance and diabetes. Hepatology 2008; 48: 792-798 [PMID: 18752331 DOI: 10.1002/hep.22429]
    • (2008) Hepatology , vol.48 , pp. 792-798
    • Fracanzani, A.L.1    Valenti, L.2    Bugianesi, E.3    Andreoletti, M.4    Colli, A.5    Vanni, E.6    Bertelli, C.7    Fatta, E.8    Bignamini, D.9    Marchesini, G.10    Fargion, S.11
  • 22
    • 4143146390 scopus 로고    scopus 로고
    • Liver damage in severely obese patients: A clinical-biochemical-morphologic study on 1,000 liver biopsies
    • [PMID: 15329185 DOI: 10.1381/0960892041719644]
    • Papadia FS, Marinari GM, Camerini G, Murelli F, Carlini F, Stabilini C, Scopinaro N. Liver damage in severely obese patients: a clinical-biochemical-morphologic study on 1,000 liver biopsies. Obes Surg 2004; 14: 952-958 [PMID: 15329185 DOI: 10.1381/0960892041719644]
    • (2004) Obes Surg , vol.14 , pp. 952-958
    • Papadia, F.S.1    Marinari, G.M.2    Camerini, G.3    Murelli, F.4    Carlini, F.5    Stabilini, C.6    Scopinaro, N.7
  • 23
    • 10644220306 scopus 로고    scopus 로고
    • Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
    • [PMID: 15565570 DOI: 10.1002/hep.20466]
    • Browning JD, Szczepaniak LS, Dobbins R, Nuremberg P, Horton JD, Cohen JC, Grundy SM, Hobbs HH. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 2004; 40: 1387-1395 [PMID: 15565570 DOI: 10.1002/hep.20466]
    • (2004) Hepatology , vol.40 , pp. 1387-1395
    • Browning, J.D.1    Szczepaniak, L.S.2    Dobbins, R.3    Nuremberg, P.4    Horton, J.D.5    Cohen, J.C.6    Grundy, S.M.7    Hobbs, H.H.8
  • 25
    • 0032412523 scopus 로고    scopus 로고
    • AST/ALT ratio predicts cirrhosis in patients with chronic hepatitis C virus infection
    • [PMID: 9448172 DOI: 10.1111/j.1572-0241.1998.044_c.x]
    • Sheth SG, Flamm SL, Gordon FD, Chopra S. AST/ALT ratio predicts cirrhosis in patients with chronic hepatitis C virus infection. Am J Gastroenterol 1998; 93: 44-48 [PMID: 9448172 DOI: 10.1111/j.1572-0241.1998.044_c.x]
    • (1998) Am J Gastroenterol , vol.93 , pp. 44-48
    • Sheth, S.G.1    Flamm, S.L.2    Gordon, F.D.3    Chopra, S.4
  • 26
    • 4444290464 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Histologic features and clinical correlations with 30 blinded biopsy specimens
    • [PMID: 15343508 DOI: 10.1016/j.humpath]
    • Brunt EM, Neuschwander-Tetri BA, Oliver D, Wehmeier KR, Bacon BR. Nonalcoholic steatohepatitis: histologic features and clinical correlations with 30 blinded biopsy specimens. Hum Pathol 2004; 35: 1070-1082 [PMID: 15343508 DOI: 10.1016/j.humpath]
    • (2004) Hum Pathol , vol.35 , pp. 1070-1082
    • Brunt, E.M.1    Neuschwander-Tetri, B.A.2    Oliver, D.3    Wehmeier, K.R.4    Bacon, B.R.5
  • 28
    • 0032822946 scopus 로고    scopus 로고
    • Prospective evaluation of unexplained chronic liver transaminase abnormalities in asymptomatic and symptomatic patients
    • [PMID: 10520861 DOI: 10.1016/S0002-9270(99)00507-9]
    • Daniel S, Ben-Menachem T, Vasudevan G, Ma CK, Blumenkehl M. Prospective evaluation of unexplained chronic liver transaminase abnormalities in asymptomatic and symptomatic patients. Am J Gastroenterol 1999; 94: 3010-3014 [PMID: 10520861 DOI: 10.1016/S0002-9270(99)00507-9]
    • (1999) Am J Gastroenterol , vol.94 , pp. 3010-3014
    • Daniel, S.1    Ben-Menachem, T.2    Vasudevan, G.3    Ma, C.K.4    Blumenkehl, M.5
  • 29
    • 0034862590 scopus 로고    scopus 로고
    • Findings on liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology
    • [PMID: 11580141 DOI: 10.1016/S0168-8278(01)00094-0]
    • Skelly MM, James PD, Ryder SD. Findings on liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology. J Hepatol 2001; 35: 195-199 [PMID: 11580141 DOI: 10.1016/S0168-8278(01)00094-0]
    • (2001) J Hepatol , vol.35 , pp. 195-199
    • Skelly, M.M.1    James, P.D.2    Ryder, S.D.3
  • 30
    • 84864244872 scopus 로고    scopus 로고
    • Metabolic syndrome, insulin resistance, and roles of inflammation--mechanisms and therapeutic targets
    • [PMID: 22815343 DOI: 10.1161/AT, VBAHA.111.241869]
    • Romeo GR, Lee J, Shoelson SE. Metabolic syndrome, insulin resistance, and roles of inflammation--mechanisms and therapeutic targets. Arterioscler Thromb Vasc Biol 2012; 32: 1771-1776 [PMID: 22815343 DOI: 10.1161/ATVBAHA.111.241869]
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 1771-1776
    • Romeo, G.R.1    Lee, J.2    Shoelson, S.E.3
  • 31
    • 79951810722 scopus 로고    scopus 로고
    • Serum total adiponectin in nonalcoholic fatty liver disease: A systematic review and meta-analysis
    • [PMID: 21040935 DOI: 10.1016/ j.metabol.2010.09.003]
    • Polyzos SA, Toulis KA, Goulis DG, Zavos C, Kountouras J. Serum total adiponectin in nonalcoholic fatty liver disease: a systematic review and meta-analysis. Metabolism 2011; 60: 313-326 [PMID: 21040935 DOI: 10.1016/ j.metabol.2010.09.003]
    • (2011) Metabolism , vol.60 , pp. 313-326
    • Polyzos, S.A.1    Toulis, K.A.2    Goulis, D.G.3    Zavos, C.4    Kountouras, J.5
  • 32
    • 66149119340 scopus 로고    scopus 로고
    • Fatty liver is associated with insulin resistance, risk of coronary heart disease, and early atherosclerosis in a large European population
    • [PMID: 19291789 DOI: 10.1002/ hep.22845]
    • Gastaldelli A, Kozakova M, Højlund K, Flyvbjerg A, Favuzzi A, Mitrakou A, Balkau B. Fatty liver is associated with insulin resistance, risk of coronary heart disease, and early atherosclerosis in a large European population. Hepatology 2009; 49: 1537-1544 [PMID: 19291789 DOI: 10.1002/ hep.22845]
    • (2009) Hepatology , vol.49 , pp. 1537-1544
    • Gastaldelli, A.1    Kozakova, M.2    Højlund, K.3    Flyvbjerg, A.4    Favuzzi, A.5    Mitrakou, A.6    Balkau, B.7
  • 33
    • 63049139758 scopus 로고    scopus 로고
    • Serum procalcitonin and CRP levels in non-alcoholic fatty liver disease: A case control study
    • [PMID: 19222849 DOI: 10.1186/1471-230X-9-16]
    • Oruc N, Ozutemiz O, Yuce G, Akarca US, Ersoz G, Gunsar F, Batur Y. Serum procalcitonin and CRP levels in non-alcoholic fatty liver disease: a case control study. BMC Gastroenterol 2009; 9: 16 [PMID: 19222849 DOI: 10.1186/1471-230X-9-16]
    • (2009) BMC Gastroenterol , vol.9 , pp. 16
    • Oruc, N.1    Ozutemiz, O.2    Yuce, G.3    Akarca, U.S.4    Ersoz, G.5    Gunsar, F.6    Batur, Y.7
  • 34
    • 0037651218 scopus 로고    scopus 로고
    • Serum levels of acute phase proteins in patients with nonalcoholic steatohepatitis
    • [PMID: 14593532]
    • Koruk M, Tayşi S, Savaş MC, Yilmaz O, Akçay F, Karakök M. Serum levels of acute phase proteins in patients with nonalcoholic steatohepatitis. Turk J Gastroenterol 2003; 14: 12-17 [PMID: 14593532]
    • (2003) Turk J Gastroenterol , vol.14 , pp. 12-17
    • Koruk, M.1    Tayşi, S.2    Savaş, M.C.3    Yilmaz, O.4    Akçay, F.5    Karakök, M.6
  • 35
    • 84885166200 scopus 로고    scopus 로고
    • Noninvasive biomarkers for the diagnosis of steatohepatitis and advanced fibrosis in NAFLD
    • [PMID: 24252302 DOI: 10.1186/2050-7771-1-7]
    • Pearce SG, Thosani NC, Pan JJ. Noninvasive biomarkers for the diagnosis of steatohepatitis and advanced fibrosis in NAFLD. Biomark Res 2013; 1: 7 [PMID: 24252302 DOI: 10.1186/2050-7771-1-7]
    • (2013) Biomark Res , vol.1 , pp. 7
    • Pearce, S.G.1    Thosani, N.C.2    Pan, J.J.3
  • 36
    • 84864847974 scopus 로고    scopus 로고
    • Diagnostic and therapeutic implications of the association between ferritin level and severity of nonalcoholic fatty liver disease
    • [PMID: 22876027 DOI: 10.3748/wjg.v18.i29.3782]
    • Valenti L, Dongiovanni P, Fargion S. Diagnostic and therapeutic implications of the association between ferritin level and severity of nonalcoholic fatty liver disease. World J Gastroenterol 2012; 18: 3782-3786 [PMID: 22876027 DOI: 10.3748/wjg.v18.i29.3782]
    • (2012) World J Gastroenterol , vol.18 , pp. 3782-3786
    • Valenti, L.1    Dongiovanni, P.2    Fargion, S.3
  • 37
    • 84155188801 scopus 로고    scopus 로고
    • Serum ferritin is an independent predictor of histologic severity and advanced fibrosis in patients with nonalcoholic fatty liver disease
    • [PMID: 21953442 DOI: 10.1002/hep.24706]
    • Kowdley KV, Belt P, Wilson LA, Yeh MM, Neuschwander-Tetri BA, Chalasani N, Sanyal AJ, Nelson JE. Serum ferritin is an independent predictor of histologic severity and advanced fibrosis in patients with nonalcoholic fatty liver disease. Hepatology 2012; 55: 77-85 [PMID: 21953442 DOI: 10.1002/hep.24706]
    • (2012) Hepatology , vol.55 , pp. 77-85
    • Kowdley, K.V.1    Belt, P.2    Wilson, L.A.3    Yeh, M.M.4    Neuschwander-Tetri, B.A.5    Chalasani, N.6    Sanyal, A.J.7    Nelson, J.E.8
  • 38
    • 79959517565 scopus 로고    scopus 로고
    • Human fatty liver disease: Old questions and new insights
    • [PMID: 21700865 DOI: 10.1126/science.1204265]
    • Cohen JC, Horton JD, Hobbs HH. Human fatty liver disease: old questions and new insights. Science 2011; 332: 1519-1523 [PMID: 21700865 DOI: 10.1126/science.1204265]
    • (2011) Science , vol.332 , pp. 1519-1523
    • Cohen, J.C.1    Horton, J.D.2    Hobbs, H.H.3
  • 39
    • 77958183243 scopus 로고    scopus 로고
    • Novel insights into the pathophysiology of nonalcoholic fatty liver disease
    • [PMID: 20960378 DOI: 10.1055/s-0030-1267539]
    • Feldstein AE. Novel insights into the pathophysiology of nonalcoholic fatty liver disease. Semin Liver Dis 2010; 30: 391-401 [PMID: 20960378 DOI: 10.1055/s-0030-1267539]
    • (2010) Semin Liver Dis , vol.30 , pp. 391-401
    • Feldstein, A.E.1
  • 40
    • 79251535913 scopus 로고    scopus 로고
    • Non-invasive diagnosis of onalcoholic fatty liver and nonalcoholic steatohepatitis
    • [PMID: 21091933 DOI: 10.1111/j.1751-2980.2010.00471. x]
    • Adams LA, Feldstein AE. Non-invasive diagnosis of onalcoholic fatty liver and nonalcoholic steatohepatitis. J Dig Dis 2011; 12: 10-16 [PMID: 21091933 DOI: 10.1111/j.1751-2980.2010.00471. x]
    • (2011) J Dig Dis , vol.12 , pp. 10-16
    • Adams, L.A.1    Feldstein, A.E.2
  • 42
    • 44949233003 scopus 로고    scopus 로고
    • Increased hepatic and circulating interleukin-6 levels in human nonalcoholic steatohepatitis
    • [PMID: 18510618 DOI: 10.1111/j.1572-0241.2007.01774.x]
    • Wieckowska A, Papouchado BG, Li Z, Lopez R, Zein NN, Feldstein AE. Increased hepatic and circulating interleukin-6 levels in human nonalcoholic steatohepatitis. Am J Gastroenterol 2008; 103: 1372-1379 [PMID: 18510618 DOI: 10.1111/j.1572-0241.2007.01774.x]
    • (2008) Am J Gastroenterol , vol.103 , pp. 1372-1379
    • Wieckowska, A.1    Papouchado, B.G.2    Li, Z.3    Lopez, R.4    Zein, N.N.5    Feldstein, A.E.6
  • 44
    • 21344458172 scopus 로고    scopus 로고
    • Apoptosis in alcoholic and nonalco-holic steatohepatitis
    • [PMID: 15970563 DOI: 10.2741/1765]
    • Feldstein AE, Gores GJ. Apoptosis in alcoholic and nonalco-holic steatohepatitis. Front Biosci 2005; 10: 3093-3099 [PMID: 15970563 DOI: 10.2741/1765]
    • (2005) Front Biosci , vol.10 , pp. 3093-3099
    • Feldstein, A.E.1    Gores, G.J.2
  • 45
    • 84864107424 scopus 로고    scopus 로고
    • Can NASH be diagnosed, graded, and staged noninvasively?
    • [PMID: 22824481 DOI: 10.1016/j.cld.2012.05.001]
    • Grandison GA, Angulo P. Can NASH be diagnosed, graded, and staged noninvasively? Clin Liver Dis 2012; 16: 567-585 [PMID: 22824481 DOI: 10.1016/j.cld.2012.05.001]
    • (2012) Clin Liver Dis , vol.16 , pp. 567-585
    • Grandison, G.A.1    Angulo, P.2
  • 46
    • 34548306754 scopus 로고    scopus 로고
    • Noninvasive diagnosis and monitoring of nonalcoholic steatohepatitis: Present and future
    • [PMID: 17661414 DOI: 10.1002/hep.21768]
    • Wieckowska A, McCullough AJ, Feldstein AE. Noninvasive diagnosis and monitoring of nonalcoholic steatohepatitis: present and future. Hepatology 2007; 46: 582-589 [PMID: 17661414 DOI: 10.1002/hep.21768]
    • (2007) Hepatology , vol.46 , pp. 582-589
    • Wieckowska, A.1    McCullough, A.J.2    Feldstein, A.E.3
  • 47
    • 70350046669 scopus 로고    scopus 로고
    • Cytokeratin-18 fragment levels as noninvasive biomarkers for nonalcoholic steatohepatitis: A multicenter validation study
    • [PMID: 19585618 DOI: 10.1002/hep.23050]
    • Feldstein AE, Wieckowska A, Lopez AR, Liu YC, Zein NN, McCullough AJ. Cytokeratin-18 fragment levels as noninvasive biomarkers for nonalcoholic steatohepatitis: a multicenter validation study. Hepatology 2009; 50: 1072-1078 [PMID: 19585618 DOI: 10.1002/hep.23050]
    • (2009) Hepatology , vol.50 , pp. 1072-1078
    • Feldstein, A.E.1    Wieckowska, A.2    Lopez, A.R.3    Liu, Y.C.4    Zein, N.N.5    McCullough, A.J.6
  • 49
    • 84883740164 scopus 로고    scopus 로고
    • Serum cytokeratin-18 fragment levels are useful biomarkers for nonalcoholic steatohepatitis in children
    • [PMID: 23752877 DOI: 10.1038/ajg.2013.168]
    • Feldstein AE, Alkhouri N, De Vito R, Alisi A, Lopez R, Nobili V. Serum cytokeratin-18 fragment levels are useful biomarkers for nonalcoholic steatohepatitis in children. Am J Gastroenterol 2013; 108: 1526-1531 [PMID: 23752877 DOI: 10.1038/ajg.2013.168]
    • (2013) Am J Gastroenterol , vol.108 , pp. 1526-1531
    • Feldstein, A.E.1    Alkhouri, N.2    de Vito, R.3    Alisi, A.4    Lopez, R.5    Nobili, V.6
  • 51
    • 84872133663 scopus 로고    scopus 로고
    • Validation of terminal peptide of procollagen III for the detection and assessment of nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease
    • [PMID: 22930399 DOI: 10.1002/hep.26030]
    • Tanwar S, Trembling PM, Guha IN, Parkes J, Kaye P, Burt AD, Ryder SD, Aithal GP, Day CP, Rosenberg WM. Validation of terminal peptide of procollagen III for the detection and assessment of nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease. Hepatology 2013; 57: 103-111 [PMID: 22930399 DOI: 10.1002/hep.26030]
    • (2013) Hepatology , vol.57 , pp. 103-111
    • Tanwar, S.1    Trembling, P.M.2    Guha, I.N.3    Parkes, J.4    Kaye, P.5    Burt, A.D.6    Ryder, S.D.7    Aithal, G.P.8    Day, C.P.9    Rosenberg, W.M.10
  • 53
    • 84862683521 scopus 로고    scopus 로고
    • Co-existence of non-alcoholic fatty liver disease with elevated alanine aminotransferase is associated with insulin resistance in young Han males
    • [PMID: 21796479 DOI: 10.1007/s12020-011-9511-0]
    • Wang R, Lu Q, Feng J, Yin F, Qin C, Liu B, Liu Y, Liu X. Co-existence of non-alcoholic fatty liver disease with elevated alanine aminotransferase is associated with insulin resistance in young Han males. Endocrine 2012; 41: 70-75 [PMID: 21796479 DOI: 10.1007/s12020-011-9511-0]
    • (2012) Endocrine , vol.41 , pp. 70-75
    • Wang, R.1    Lu, Q.2    Feng, J.3    Yin, F.4    Qin, C.5    Liu, B.6    Liu, Y.7    Liu, X.8
  • 54
    • 34547539428 scopus 로고    scopus 로고
    • Usefulness of a combined evaluation of the serum adiponectin level, HOMA-IR, and serum type IV collagen 7S level to predict the early stage of nonalcoholic steatohepatitis
    • [PMID: 17511754 DOI: 10.1111/j.1572-0241.2007]
    • Shimada M, Kawahara H, Ozaki K, Fukura M, Yano H, Tsuchishima M, Tsutsumi M, Takase S. Usefulness of a combined evaluation of the serum adiponectin level, HOMA-IR, and serum type IV collagen 7S level to predict the early stage of nonalcoholic steatohepatitis. Am J Gastroenterol 2007; 102: 1931-1938 [PMID: 17511754 DOI: 10.1111/j.1572-0241.2007]
    • (2007) Am J Gastroenterol , vol.102 , pp. 1931-1938
    • Shimada, M.1    Kawahara, H.2    Ozaki, K.3    Fukura, M.4    Yano, H.5    Tsuchishima, M.6    Tsutsumi, M.7    Takase, S.8
  • 55
    • 79960979728 scopus 로고    scopus 로고
    • APRI: A simple bedside marker for advanced fibrosis that can avoid liver biopsy in patients with NAFLD/NASH
    • [PMID: 21920102]
    • Kruger FC, Daniels CR, Kidd M, Swart G, Brundyn K, van Rensburg C, Kotze M. APRI: a simple bedside marker for advanced fibrosis that can avoid liver biopsy in patients with NAFLD/NASH. S Afr Med J 2011; 101: 477-480 [PMID: 21920102]
    • (2011) S Afr Med J , vol.101 , pp. 477-480
    • Kruger, F.C.1    Daniels, C.R.2    Kidd, M.3    Swart, G.4    Brundyn, K.5    van Rensburg, C.6    Kotze, M.7
  • 56
    • 84859324858 scopus 로고    scopus 로고
    • Noninvasive parameters and hepatic fibrosis scores in children with nonalcoholic fatty liver disease
    • [PMID: 22509085 DOI: 10.3748/wjg.v18.i13.1525]
    • Yang HR, Kim HR, Kim MJ, Ko JS, Seo JK. Noninvasive parameters and hepatic fibrosis scores in children with nonalcoholic fatty liver disease. World J Gastroenterol 2012; 18: 1525-1530 [PMID: 22509085 DOI: 10.3748/wjg.v18.i13.1525]
    • (2012) World J Gastroenterol , vol.18 , pp. 1525-1530
    • Yang, H.R.1    Kim, H.R.2    Kim, M.J.3    Ko, J.S.4    Seo, J.K.5
  • 57
    • 34547483053 scopus 로고    scopus 로고
    • FIB-4: An inexpensive and accurate marker of fibrosis in HCV infection. comparison with liver biopsy and fibrotest
    • [PMID: 17567829 DOI: 10.1002/hep.21669]
    • Vallet-Pichard A, Mallet V, Nalpas B, Verkarre V, Nalpas A, Dhalluin-Venier V, Fontaine H, Pol S. FIB-4: an inexpensive and accurate marker of fibrosis in HCV infection. comparison with liver biopsy and fibrotest. Hepatology 2007; 46: 32-36 [PMID: 17567829 DOI: 10.1002/hep.21669]
    • (2007) Hepatology , vol.46 , pp. 32-36
    • Vallet-Pichard, A.1    Mallet, V.2    Nalpas, B.3    Verkarre, V.4    Nalpas, A.5    Dhalluin-Venier, V.6    Fontaine, H.7    Pol, S.8
  • 58
    • 70349546276 scopus 로고    scopus 로고
    • Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease
    • [PMID: 19523535 DOI: 10.1016/j.cgh.2009.05.033]
    • Shah AG, Lydecker A, Murray K, Tetri BN, Contos MJ, Sanyal AJ. Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol 2009; 7: 1104-1112 [PMID: 19523535 DOI: 10.1016/j.cgh.2009.05.033]
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 1104-1112
    • Shah, A.G.1    Lydecker, A.2    Murray, K.3    Tetri, B.N.4    Contos, M.J.5    Sanyal, A.J.6
  • 59
    • 77956119396 scopus 로고    scopus 로고
    • Simple non-invasive fibrosis scoring systems can reliably exclude advanced fibrosis in patients with non-alcoholic fatty liver disease
    • [PMID: 20801772 DOI: 10.1136/gut.2010]
    • McPherson S, Stewart SF, Henderson E, Burt AD, Day CP. Simple non-invasive fibrosis scoring systems can reliably exclude advanced fibrosis in patients with non-alcoholic fatty liver disease. Gut 2010; 59: 1265-1269 [PMID: 20801772 DOI: 10.1136/gut.2010]
    • (2010) Gut , vol.59 , pp. 1265-1269
    • McPherson, S.1    Stewart, S.F.2    Henderson, E.3    Burt, A.D.4    Day, C.P.5
  • 61
    • 41349094999 scopus 로고    scopus 로고
    • Performance of transient elastography for the staging of liver fibrosis: A meta-analysis
    • [PMID: 18395077 DOI: 10.1053/j.gastro.2008.01.034]
    • Friedrich-Rust M, Ong MF, Martens S, Sarrazin C, Bojunga J, Zeuzem S, Herrmann E. Performance of transient elastography for the staging of liver fibrosis: a meta-analysis. Gastroenterology 2008; 134: 960-974 [PMID: 18395077 DOI: 10.1053/j.gastro.2008.01.034]
    • (2008) Gastroenterology , vol.134 , pp. 960-974
    • Friedrich-Rust, M.1    Ong, M.F.2    Martens, S.3    Sarrazin, C.4    Bojunga, J.5    Zeuzem, S.6    Herrmann, E.7
  • 64
    • 84155188892 scopus 로고    scopus 로고
    • Feasibility and diagnostic performance of the FibroScan XL probe for liver stiffness measurement in overweight and obese patients
    • [PMID: 21898479 DOI: 10.1002/hep.24624]
    • Myers RP, Pomier-Layrargues G, Kirsch R, Pollett A, Duarte-Rojo A, Wong D, Beaton M, Levstik M, Crotty P, Elkashab M. Feasibility and diagnostic performance of the FibroScan XL probe for liver stiffness measurement in overweight and obese patients. Hepatology 2012; 55: 199-208 [PMID: 21898479 DOI: 10.1002/hep.24624]
    • (2012) Hepatology , vol.55 , pp. 199-208
    • Myers, R.P.1    Pomier-Layrargues, G.2    Kirsch, R.3    Pollett, A.4    Duarte-Rojo, A.5    Wong, D.6    Beaton, M.7    Levstik, M.8    Crotty, P.9    Elkashab, M.10
  • 65
    • 84859113868 scopus 로고    scopus 로고
    • Assessment by Fibroscan of fibrosis in non-alcoholic fatty liver disease: XL versus M probe?
    • author reply 1309-1310, [PMID: 22307871 DOI: 10.1002/hep.25638]
    • Petta S, Craxì A. Assessment by Fibroscan of fibrosis in non-alcoholic fatty liver disease: XL versus M probe? Hepatology 2012; 55: 1309; author reply 1309-1310 [PMID: 22307871 DOI: 10.1002/hep.25638]
    • (2012) Hepatology , vol.55 , pp. 1309
    • Petta, S.1    Craxì, A.2
  • 66
    • 80053912735 scopus 로고    scopus 로고
    • Is it better to use two elastographic methods for liver fibrosis assessment?
    • [PMID: 21987625 DOI: 10.3748/wjg.v17.i33.3824]
    • Sporea I, Şirli R, Popescu A, Bota S, Badea R, Lupşor M, Focşa M, Dǎnilǎ M. Is it better to use two elastographic methods for liver fibrosis assessment? World J Gastroenterol 2011; 17: 3824-3829 [PMID: 21987625 DOI: 10.3748/wjg.v17.i33.3824]
    • (2011) World J Gastroenterol , vol.17 , pp. 3824-3829
    • Sporea, I.1    Şirli, R.2    Popescu, A.3    Bota, S.4    Badea, R.5    Lupşor, M.6    Focşa, M.7    Dǎnilǎ, M.8
  • 67
    • 43949144276 scopus 로고    scopus 로고
    • Noninvasive assessment of hepatic lipid composition: Advancing understanding and management of fatty liver disorders
    • [PMID: 18393289 DOI: 10.1002/ hep.22220]
    • Johnson NA, Walton DW, Sachinwalla T, Thompson CH, Smith K, Ruell PA, Stannard SR, George J. Noninvasive assessment of hepatic lipid composition: Advancing understanding and management of fatty liver disorders. Hepatology 2008; 47: 1513-1523 [PMID: 18393289 DOI: 10.1002/ hep.22220]
    • (2008) Hepatology , vol.47 , pp. 1513-1523
    • Johnson, N.A.1    Walton, D.W.2    Sachinwalla, T.3    Thompson, C.H.4    Smith, K.5    Ruell, P.A.6    Stannard, S.R.7    George, J.8
  • 68
    • 84865569519 scopus 로고    scopus 로고
    • Effect of colesevelam on liver fat quantified by magnetic resonance in nonalcoholic steatohepatitis: A randomized controlled trial
    • [PMID: 22431131 DOI: 10.1002/ hep.25731]
    • Le TA, Chen J, Changchien C, Peterson MR, Kono Y, Patton H, Cohen BL, Brenner D, Sirlin C, Loomba R. Effect of colesevelam on liver fat quantified by magnetic resonance in nonalcoholic steatohepatitis: a randomized controlled trial. Hepatology 2012; 56: 922-932 [PMID: 22431131 DOI: 10.1002/ hep.25731]
    • (2012) Hepatology , vol.56 , pp. 922-932
    • Le, T.A.1    Chen, J.2    Changchien, C.3    Peterson, M.R.4    Kono, Y.5    Patton, H.6    Cohen, B.L.7    Brenner, D.8    Sirlin, C.9    Loomba, R.10
  • 69
    • 77953309273 scopus 로고    scopus 로고
    • Magnetic resonance elastography: A review
    • [PMID: 20544947 DOI: 10.1002/ca.21006]
    • Mariappan YK, Glaser KJ, Ehman RL. Magnetic resonance elastography: a review. Clin Anat 2010; 23: 497-511 [PMID: 20544947 DOI: 10.1002/ca.21006]
    • (2010) Clin Anat , vol.23 , pp. 497-511
    • Mariappan, Y.K.1    Glaser, K.J.2    Ehman, R.L.3
  • 70
    • 80054757186 scopus 로고    scopus 로고
    • MR elastography for noninvasive assessment of hepatic fibrosis: Experience from a tertiary center in Asia
    • [PMID: 21932355 DOI: 10.1002/jmri.22723]
    • Kim BH, Lee JM, Lee YJ, Lee KB, Suh KS, Han JK, Choi BI. MR elastography for noninvasive assessment of hepatic fibrosis: experience from a tertiary center in Asia. J Magn Reson Imaging 2011; 34: 1110-1116 [PMID: 21932355 DOI: 10.1002/jmri.22723]
    • (2011) J Magn Reson Imaging , vol.34 , pp. 1110-1116
    • Kim, B.H.1    Lee, J.M.2    Lee, Y.J.3    Lee, K.B.4    Suh, K.S.5    Han, J.K.6    Choi, B.I.7
  • 71
    • 79956292596 scopus 로고    scopus 로고
    • Early detection of nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease by using MR elastography
    • [PMID: 21460032 DOI: 10.1148/radiol.11101942]
    • Chen J, Talwalkar JA, Yin M, Glaser KJ, Sanderson SO, Ehman RL. Early detection of nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease by using MR elastography. Radiology 2011; 259: 749-756 [PMID: 21460032 DOI: 10.1148/radiol.11101942]
    • (2011) Radiology , vol.259 , pp. 749-756
    • Chen, J.1    Talwalkar, J.A.2    Yin, M.3    Glaser, K.J.4    Sanderson, S.O.5    Ehman, R.L.6
  • 74
    • 75449088414 scopus 로고    scopus 로고
    • Decreased survival of subjects with elevated liver function tests during a 28-year follow-up
    • [PMID: 20014114 DOI: 10.1002/ hep.23314]
    • Söderberg C, Stål P, Askling J, Glaumann H, Lindberg G, Marmur J, Hultcrantz R. Decreased survival of subjects with elevated liver function tests during a 28-year follow-up. Hepatology 2010; 51: 595-602 [PMID: 20014114 DOI: 10.1002/ hep.23314]
    • (2010) Hepatology , vol.51 , pp. 595-602
    • Söderberg, C.1    Stål, P.2    Askling, J.3    Glaumann, H.4    Lindberg, G.5    Marmur, J.6    Hultcrantz, R.7
  • 75
    • 0033531215 scopus 로고    scopus 로고
    • Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group
    • [PMID: 9878640 DOI: 10.1056/NEJM199901073400103]
    • O'Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. N Engl J Med 1999; 340: 14-22 [PMID: 9878640 DOI: 10.1056/NEJM199901073400103]
    • (1999) N Engl J Med , vol.340 , pp. 14-22
    • O'Leary, D.H.1    Polak, J.F.2    Kronmal, R.A.3    Manolio, T.A.4    Burke, G.L.5    Wolfson, S.K.6
  • 77
    • 50849096389 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease is strongly associated with carotid atherosclerosis: A systematic review
    • [PMID: 18672311 DOI: 10.1016/j.jhep.2008.06.012]
    • Sookoian S, Pirola CJ. Non-alcoholic fatty liver disease is strongly associated with carotid atherosclerosis: a systematic review. J Hepatol 2008; 49: 600-607 [PMID: 18672311 DOI: 10.1016/j.jhep.2008.06.012]
    • (2008) J Hepatol , vol.49 , pp. 600-607
    • Sookoian, S.1    Pirola, C.J.2
  • 78
    • 69049111026 scopus 로고    scopus 로고
    • Elevation of serum aminotransferase activity increases risk of carotid atherosclerosis in patients with non-alcoholic fatty liver disease
    • [PMID: 19702910 DOI: 10.1111/ j.1440-1746.2009.05872.x]
    • Wang CC, Lin SK, Tseng YF, Hsu CS, Tseng TC, Lin HH, Wang LY, Kao JH. Elevation of serum aminotransferase activity increases risk of carotid atherosclerosis in patients with non-alcoholic fatty liver disease. J Gastroenterol Hepatol 2009; 24: 1411-1416 [PMID: 19702910 DOI: 10.1111/ j.1440-1746.2009.05872.x]
    • (2009) J Gastroenterol Hepatol , vol.24 , pp. 1411-1416
    • Wang, C.C.1    Lin, S.K.2    Tseng, Y.F.3    Hsu, C.S.4    Tseng, T.C.5    Lin, H.H.6    Wang, L.Y.7    Kao, J.H.8
  • 79
    • 33746421488 scopus 로고    scopus 로고
    • Relations between carotid artery wall thickness and liver histology in subjects with nonalcoholic fatty liver disease
    • [PMID: 16732016 DOI: 10.2337/dc06-0135]
    • Targher G, Bertolini L, Padovani R, Rodella S, Zoppini G, Zenari L, Cigolini M, Falezza G, Arcaro G. Relations between carotid artery wall thickness and liver histology in subjects with nonalcoholic fatty liver disease. Diabetes Care 2006; 29: 1325-1330 [PMID: 16732016 DOI: 10.2337/dc06-0135]
    • (2006) Diabetes Care , vol.29 , pp. 1325-1330
    • Targher, G.1    Bertolini, L.2    Padovani, R.3    Rodella, S.4    Zoppini, G.5    Zenari, L.6    Cigolini, M.7    Falezza, G.8    Arcaro, G.9
  • 80
    • 84875210688 scopus 로고    scopus 로고
    • The severity of Fatty liver disease relating to metabolic abnormalities independently predicts coronary calcification
    • [PMID: 22254139 DOI: 10.1155/2011/586785]
    • Lee YH, Wu YJ, Liu CC, Hou CJ, Yeh HI, Tsai CH, Shih SC, Hung CL. The severity of Fatty liver disease relating to metabolic abnormalities independently predicts coronary calcification. Radiol Res Pract 2011; 2011: 586785 [PMID: 22254139 DOI: 10.1155/2011/586785]
    • (2011) Radiol Res Pract , vol.2011 , pp. 586785
    • Lee, Y.H.1    Wu, Y.J.2    Liu, C.C.3    Hou, C.J.4    Yeh, H.I.5    Tsai, C.H.6    Shih, S.C.7    Hung, C.L.8
  • 81
    • 77954423206 scopus 로고    scopus 로고
    • Association between nonalcoholic fatty liver disease and coronary artery calcification
    • [PMID: 19688595 DOI: 10.1007/s10620-009-0935-9]
    • Chen CH, Nien CK, Yang CC, Yeh YH. Association between nonalcoholic fatty liver disease and coronary artery calcification. Dig Dis Sci 2010; 55: 1752-1760 [PMID: 19688595 DOI: 10.1007/s10620-009-0935-9]
    • (2010) Dig Dis Sci , vol.55 , pp. 1752-1760
    • Chen, C.H.1    Nien, C.K.2    Yang, C.C.3    Yeh, Y.H.4
  • 82
    • 77449127455 scopus 로고    scopus 로고
    • Presence of coronary plaques in patients with nonalcoholic fatty liver disease
    • [PMID: 20093511 DOI: 10.1148/radiol.09090769]
    • Assy N, Djibre A, Farah R, Grosovski M, Marmor A. Presence of coronary plaques in patients with nonalcoholic fatty liver disease. Radiology 2010; 254: 393-400 [PMID: 20093511 DOI: 10.1148/radiol.09090769]
    • (2010) Radiology , vol.254 , pp. 393-400
    • Assy, N.1    Djibre, A.2    Farah, R.3    Grosovski, M.4    Marmor, A.5
  • 83
    • 80655144446 scopus 로고    scopus 로고
    • Coronary artery disease and cardiovascular outcomes in patients with non-alcoholic fatty liver disease
    • [PMID: 21602530 DOI: 10.1136/gut.2011.242016]
    • Wong VW, Wong GL, Yip GW, Lo AO, Limquiaco J, Chu WC, Chim AM, Yu CM, Yu J, Chan FK, Sung JJ, Chan HL. Coronary artery disease and cardiovascular outcomes in patients with non-alcoholic fatty liver disease. Gut 2011; 60: 1721-1727 [PMID: 21602530 DOI: 10.1136/gut.2011.242016]
    • (2011) Gut , vol.60 , pp. 1721-1727
    • Wong, V.W.1    Wong, G.L.2    Yip, G.W.3    Lo, A.O.4    Limquiaco, J.5    Chu, W.C.6    Chim, A.M.7    Yu, C.M.8    Yu, J.9    Chan, F.K.10    Sung, J.J.11    Chan, H.L.12
  • 84
    • 10744221815 scopus 로고    scopus 로고
    • Clinical correlates and heritability of flow-mediated dilation in the community: The Framingham Heart Study
    • [PMID: 14769683 DOI: 10.1161/01. CIR.0000112565.60887.1E]
    • Benjamin EJ, Larson MG, Keyes MJ, Mitchell GF, Vasan RS, Keaney JF, Lehman BT, Fan S, Osypiuk E, Vita JA. Clinical correlates and heritability of flow-mediated dilation in the community: the Framingham Heart Study. Circulation 2004; 109: 613-619 [PMID: 14769683 DOI: 10.1161/01. CIR.0000112565.60887.1E]
    • (2004) Circulation , vol.109 , pp. 613-619
    • Benjamin, E.J.1    Larson, M.G.2    Keyes, M.J.3    Mitchell, G.F.4    Vasan, R.S.5    Keaney, J.F.6    Lehman, B.T.7    Fan, S.8    Osypiuk, E.9    Vita, J.A.10
  • 85
    • 23044512117 scopus 로고    scopus 로고
    • Endothelial dysfunction and cardiovascular risk profile in nonalcoholic fatty liver disease
    • [PMID: 15981216 DOI: 10.1002/hep.20781]
    • Villanova N, Moscatiello S, Ramilli S, Bugianesi E, Magalotti D, Vanni E, Zoli M, Marchesini G. Endothelial dysfunction and cardiovascular risk profile in nonalcoholic fatty liver disease. Hepatology 2005; 42: 473-480 [PMID: 15981216 DOI: 10.1002/hep.20781]
    • (2005) Hepatology , vol.42 , pp. 473-480
    • Villanova, N.1    Moscatiello, S.2    Ramilli, S.3    Bugianesi, E.4    Magalotti, D.5    Vanni, E.6    Zoli, M.7    Marchesini, G.8
  • 86
    • 78650992780 scopus 로고    scopus 로고
    • Age-related differences in the clinical presentation, associated metabolic abnormality, and estimated cardiovascular risks from nonalcoholic fatty liver disease: A cross-sectional study from health evaluation center in Taiwan
    • [DOI: 10.1016/j.ijge.2010.11.005]
    • Liu CC, Hung CL, Shih SC, Ko HJ, Lu YT, Wu YJ, Cheng HY, Hu KC, Yeh HI, Chang RE. Age-related differences in the clinical presentation, associated metabolic abnormality, and estimated cardiovascular risks from nonalcoholic fatty liver disease: a cross-sectional study from health evaluation center in Taiwan. Inter J Gerontol 2010; 4: 184-191 [DOI: 10.1016/j.ijge.2010.11.005]
    • (2010) Inter J Gerontol , vol.4 , pp. 184-191
    • Liu, C.C.1    Hung, C.L.2    Shih, S.C.3    Ko, H.J.4    Lu, Y.T.5    Wu, Y.J.6    Cheng, H.Y.7    Hu, K.C.8    Yeh, H.I.9    Chang, R.E.10
  • 87
    • 0037078969 scopus 로고    scopus 로고
    • Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events
    • [PMID: 12432042 DOI: 10.1056/NEJMoa021993]
    • Ridker PM, Rifai N, Rose L, Buring JE, Cook NR. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med 2002; 347: 1557-1565 [PMID: 12432042 DOI: 10.1056/NEJMoa021993]
    • (2002) N Engl J Med , vol.347 , pp. 1557-1565
    • Ridker, P.M.1    Rifai, N.2    Rose, L.3    Buring, J.E.4    Cook, N.R.5
  • 89
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: A tale of two "hits"?
    • [PMID: 9547102 DOI: 10.1016/S0016-5085(98)70599-2]
    • Day CP, James OF. Steatohepatitis: a tale of two "hits"? Gastroenterology 1998; 114: 842-845 [PMID: 9547102 DOI: 10.1016/S0016-5085(98)70599-2]
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.P.1    James, O.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.