Serum procalcitonin and CRP levels in non-alcoholic fatty liver disease: A case control study

BMC Gastroenterology

Volumn 9, Issue , 2009, Pages

  Oruc, Nevin ^a   Ozutemiz, Omer ^a   Yuce, Gul ^a   Akarca, Ulus S ^a   Ersoz, Galip ^a   Gunsar, Fulya ^a   Batur, Yucel ^a  

^a EGE UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; INSULIN; PROCALCITONIN; CALCITONIN; PROTEIN PRECURSOR;

ADULT; ARTICLE; BODY MASS; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; ECHOGRAPHY; FATTY LIVER; FEMALE; HUMAN; INSULIN RESISTANCE; LIVER BIOPSY; LIVER FUNCTION TEST; MALE; NONALCOHOLIC FATTY LIVER; PROTEIN BLOOD LEVEL; STEATOSIS; AGED; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; HEPATITIS; METABOLISM; MIDDLE AGED; PREDICTIVE VALUE; RECEIVER OPERATING CHARACTERISTIC; RISK FACTOR;

ADULT; AGED; BIOLOGICAL MARKERS; BODY MASS INDEX; C-REACTIVE PROTEIN; CALCITONIN; FATTY LIVER; FEMALE; HEPATITIS; HUMANS; INSULIN RESISTANCE; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROTEIN PRECURSORS; RISK FACTORS; ROC CURVE;

EID: 63049139758     PISSN: None     EISSN: 1471230X     Source Type: Journal    
DOI: 10.1186/1471-230X-9-16     Document Type: Article

References (21)

1. Farrell GC Non-alcoholic steatohepatitis: What is it, and why is it important in the Asia-Pacific region? J Gastroenterol Hepatol 2003, 18:124-138 10.1046/j.1440-1746.2003.02989.x 12542595
2. Angulo P Nonalcoholic fatty liver disease N Engl J Med 2002, 18:1221-1231 10.1056/NEJMra011775
3. Chitturi S Abeygunasakera S Farrell GC Holmes-Walker J Hui JM Fung C Karim R Lin R Samarasinghe D Liddle C Weltman M George J NASH and insulin hypersecretion and specific association with the insulin resistance syndrome Hepatology 2002, 35:373-379 10.1053/jhep.2002.30692 11826411
4. Björnsson E The clinical aspects of non-alcoholic fatty liver disease Minerva Gastroenterol Dietol 2008, 54:1-7 18 18299664
5. Massaro KS Costa SF Leone C Chamone DA Procalcitonin (PCT) and C-reactive protein (CRP) as severe systemic infection markers in febrile neutropenic adults BMC Infect Dis 2007, 22:137 10.1186/1471-2334-7-137
6. Yudkin JS Stehouwer CD Emeis JJ Coppack SW C-reactive protein in healthy subjects: Associations with obesity, insulin resistance, and endothelial dysfunction: A potential role for cytokines originating from adipose tissue? Arterioscler Thromb Vasc Biol 1999, 19:972-978 10195925
7. Danesh J Whincup P Walker M Lennon L Thomson A Appleby P Gallimore JR Pepys MB Low grade inflammation and coronary heart disease: Prospective study and updated meta-analyses BMJ 2000, 321:199-204 27435 10903648 10.1136/bmj.321.7255.199
8. Ridker PM Hennekens CH Buring JE Rifai N C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women N Engl J Med 2000, 342:836-843 10.1056/NEJM200003233421202 10733371
9. Simon L Gauvin F Amre DK Saint-Louis P Lacroix J Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: A systematic review and meta-analysis Clin Infect Dis 2004, 39:206-217 10.1086/421997 15307030
10. Maruna P Nedelnikova K Gurlich R Physiology and genetics of procalcitonin Physiol Res 2000, 49(Suppl 1):S57-S61 10984072
11. Matthews DR Hoskër JP Rudenski AS Naylor BA Treacher DF Tumer RC Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 1985, 28:412-419 10.1007/BF00280883 3899825
12. Connert S Stremmel W Elsing C Procalcitonin is a valid marker of infection in decompensated cirrhosis Z Gastroenterol 2003, 41:165-170 10.1055/s-2003-37314 12592597
13. Viallon A Zeni F Pouzet V Lambert C Quenet S Aubert G Guyomarch S Tardy B Bertrand JC Serum and ascitic procalcitonin levels in cirrhotic patients with spontaneous bacterial peritonitis: Diagnostic value and relationship to pro-inflammatory cytokines Intensive Care Med 2000, 26:1082-1088 10.1007/s001340051321 11030164
14. Elefsiniotis IS Skounakis M Vezali E Pantazis KD Petrocheilou A Pirounaki M Papatsibas G Kontou-Kastellanou C Moulakakis A Clinical significance of serum procalcitonin levels in patients with acute or chronic liver disease Eur J Gastroenterol Hepatol 2006, 18:525-530 10.1097/00042737-200605000-00012 16607149
15. Spahr L Morard I Hadengue A Vadas L Pugin J Procalcitonin is not an accurate marker of spontaneous bacterial peritonitis in patients with cirrhosis Hepatogastroenterology 2001, 48:502-505 11379342
16. Haukeland JW Damås JK Konopski Z Løberg EM Haaland T Goverud I Torjesen PA Birkeland K Bjøro K Aukrust P Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2 J Hepatol 2006, 44:1167-1174 10.1016/ j.jhep.2006.02.011 16618517
17. Yoneda M Mawatari H Fujita K Iida H Yonemitsu K Kato S Takahashi H Kirikoshi H Inamori M Nozaki Y Abe Y Kubota K Saito S Iwasaki T Terauchi Y Togo S Maeyama S Nakajima A High-sensitivity C-reactive protein is an independent clinical feature of nonalcoholic steatohepatitis (NASH) and also of the severity of fibrosis in NASH J Gastroenterol 2007, 42:573-582 10.1007/s00535-007-2060-x 17653654
18. Riquelme A Arrese M Soza A Morales A Baudrand R Pérez-Ayuso RM González R Alvarez M Hernández V García-Zattera MJ Otarola F Medina B Rigotti A Miquel JF Marshall G Nervi F Non-alcoholic fatty liver disease and its association with obesity, insulin resistance and increased serum levels of C-reactive protein in Hispanics Liver Int 2009, 29:82-88 10.1111/j.1478-3231.2008.01925.x 18647235
19. Kao PC Shiesh SC Wu TJ Serum C-reactive protein as a marker for wellness assessment Ann Clin Lab Sci 2006, 36:163-169 16682512
20. Anty R Bekri S Luciani N Saint-Paul MC Dahman M Iannelli A Amor IB Staccini-Myx A Huet PM Gugenheim J Sadoul JL Le Marchand-Brustel Y Tran A Gual P The inflammatory C-reactive protein is increased in both liver and adipose tissue in severely obese patients independently from metabolic syndrome, Type 2 diabetes, and NASH Am J Gastroenterol 2006, 101:1824-1833 10.1111/j.1572-0241.2006.00724.x 16790033
21. Dandona P Nix D Wilson MF Aljada A Love J Assicot M Bohuon C Procalcitonin increase after endotoxin injection in normal subjects J Clin Endocrinol Metab 1994, 79:1605-1608 10.1210/jc.79.6.1605 7989463