DLX5, FGF8 and the Pin1 isomerase control ΔNp63α protein stability during limb development: A regulatory loop at the basis of the SHFM and EEC congenital malformations

Human Molecular Genetics

Volumn 23, Issue 14, 2014, Pages 3830-3842

  Restelli, Michela ^a   Lopardo, Teresa ^a   Lo Iacono, Nadia ^a   Garaffo, Giulia ^b   Conte, Daniele ^b   Rustighi, Alessandra ^c   Napoli, Marco ^d   Del Sal, Giannino ^c   Perez Morga, David ^e   Costanzo, Antonio ^f   Merlo, Giorgio Roberto ^b   Guerrini, Luisa ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c AREA Science Park   (Italy)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^f UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 8; NP63ALPHA PROTEIN; PEPTIDYLPROLYL ISOMERASE PIN1; PROTEASOME; PROTEIN P63; TRANSCRIPTION FACTOR DLX5; UNCLASSIFIED DRUG; DLX5 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; NIMA-INTERACTING PEPTIDYLPROLYL ISOMERASE; PEPTIDYLPROLYL ISOMERASE; PHOSPHOPROTEIN; TRANSACTIVATOR PROTEIN; TRP63 PROTEIN, MOUSE;

ARTICLE; ECTRODACTYLY; EEC SYNDROME; IN VIVO STUDY; LIMB BUD; LIMB DEVELOPMENT; LIMB MALFORMATION; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; ANIMAL; CELL LINE; DISEASE MODEL; ECTODERM; EMBRYOLOGY; GENE INACTIVATION; GENETICS; HUMAN; METABOLISM; MOUSE; PATHOLOGY;

ANIMALS; BODY PATTERNING; CELL LINE; DISEASE MODELS, ANIMAL; ECTODERM; FIBROBLAST GROWTH FACTOR 8; GENE KNOCKOUT TECHNIQUES; HOMEODOMAIN PROTEINS; HUMANS; LIMB BUDS; LIMB DEFORMITIES, CONGENITAL; MICE; PEPTIDYLPROLYL ISOMERASE; PHOSPHOPROTEINS; PROTEIN STABILITY; TRANS-ACTIVATORS;

EID: 84902993110     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu096     Document Type: Article

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