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Volumn 8, Issue 1, 2014, Pages

Systems biology modeling of omics data: Effect of cyclosporine a on the Nrf2 pathway in human renal cells

Author keywords

Bayesian data analysis; Cyclosporine A; Glutathione pathway; Integrated omics; Nrf2 pathway; Oxidative stress; Renal proximal tubule epithelial cells; Systems biology

Indexed keywords

CYCLOSPORIN; MESSENGER RNA; NFE2L2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR NRF2;

EID: 84902897905     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-8-76     Document Type: Article
Times cited : (39)

References (39)
  • 3
    • 84855906454 scopus 로고    scopus 로고
    • Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
    • Zhao S, Iyengar R. Systems pharmacology: network analysis to identify multiscale mechanisms of drug action. Annu Rev Pharmacol Toxicol 2012, 52:505-521.
    • (2012) Annu Rev Pharmacol Toxicol , vol.52 , pp. 505-521
    • Zhao, S.1    Iyengar, R.2
  • 4
    • 65649097629 scopus 로고    scopus 로고
    • GNU MCSim: Bayesian statistical inference for SBML-coded systems biology models
    • Bois FY. GNU MCSim: Bayesian statistical inference for SBML-coded systems biology models. Bioinformatics 2009, 25:1453-1454.
    • (2009) Bioinformatics , vol.25 , pp. 1453-1454
    • Bois, F.Y.1
  • 6
    • 84864745214 scopus 로고    scopus 로고
    • Cyclosporine: a review
    • Tedesco D, Haragsim L. Cyclosporine: a review. J Transplant 2012, 2012:230386.
    • (2012) J Transplant , vol.2012 , pp. 230386
    • Tedesco, D.1    Haragsim, L.2
  • 7
    • 84878359254 scopus 로고    scopus 로고
    • Transporters and drug-drug interactions: important determinants of drug disposition and effects
    • König J, Müller F, Fromm MF. Transporters and drug-drug interactions: important determinants of drug disposition and effects. Pharmacol Rev 2013, 65:944-966.
    • (2013) Pharmacol Rev , vol.65 , pp. 944-966
    • König, J.1    Müller, F.2    Fromm, M.F.3
  • 9
    • 0029806297 scopus 로고    scopus 로고
    • Chronic cyclosporine nephropathy: the Achilles' heel of immunosuppressive therapy
    • Bennett WM, DeMattos A, Meyer MM, Andoh T, Barry JM. Chronic cyclosporine nephropathy: the Achilles' heel of immunosuppressive therapy. Kidney Int 1996, 50:1089-1100.
    • (1996) Kidney Int , vol.50 , pp. 1089-1100
    • Bennett, W.M.1    DeMattos, A.2    Meyer, M.M.3    Andoh, T.4    Barry, J.M.5
  • 12
    • 84872335543 scopus 로고    scopus 로고
    • An overview of transcriptional regulation in response to toxicological insult
    • Jennings P, Limonciel A, Felice L, Leonard MO. An overview of transcriptional regulation in response to toxicological insult. Arch Toxicol 2013, 87:49-72.
    • (2013) Arch Toxicol , vol.87 , pp. 49-72
    • Jennings, P.1    Limonciel, A.2    Felice, L.3    Leonard, M.O.4
  • 14
    • 79952039812 scopus 로고    scopus 로고
    • Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity
    • Wilmes A, Crean D, Aydin S, Pfaller W, Jennings P, Leonard MO. Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity. Toxicol In Vitro 2011, 25:613-622.
    • (2011) Toxicol In Vitro , vol.25 , pp. 613-622
    • Wilmes, A.1    Crean, D.2    Aydin, S.3    Pfaller, W.4    Jennings, P.5    Leonard, M.O.6
  • 15
    • 84862021685 scopus 로고    scopus 로고
    • Glucose reintroduction triggers the activation of Nrf2 during experimental ischemia reperfusion
    • Crean D, Felice L, Taylor CT, Rabb H, Jennings P, Leonard MO. Glucose reintroduction triggers the activation of Nrf2 during experimental ischemia reperfusion. Mol Cell Biochem 2012, 366:231-238.
    • (2012) Mol Cell Biochem , vol.366 , pp. 231-238
    • Crean, D.1    Felice, L.2    Taylor, C.T.3    Rabb, H.4    Jennings, P.5    Leonard, M.O.6
  • 16
    • 65749113675 scopus 로고    scopus 로고
    • Phase I to II cross-induction of xenobiotic metabolizing enzymes: a feedforward control mechanism for potential hormetic responses
    • Zhang Q, Pi J, Woods CG, Andersen ME. Phase I to II cross-induction of xenobiotic metabolizing enzymes: a feedforward control mechanism for potential hormetic responses. Toxicol Appl Pharmacol 2009, 237:345-356.
    • (2009) Toxicol Appl Pharmacol , vol.237 , pp. 345-356
    • Zhang, Q.1    Pi, J.2    Woods, C.G.3    Andersen, M.E.4
  • 18
    • 77958115724 scopus 로고    scopus 로고
    • Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases
    • Villeneuve NF, Lau A, Zhang DD. Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases. Antioxid Redox Signal 2010, 13:1699-1712.
    • (2010) Antioxid Redox Signal , vol.13 , pp. 1699-1712
    • Villeneuve, N.F.1    Lau, A.2    Zhang, D.D.3
  • 19
    • 0034685897 scopus 로고    scopus 로고
    • Transcriptional regulation of the antioxidant response element. Activation by Nrf2 and repression by MafK
    • Nguyen T, Huang HC, Pickett CB. Transcriptional regulation of the antioxidant response element. Activation by Nrf2 and repression by MafK. J Biol Chem 2000, 275:15466-15473.
    • (2000) J Biol Chem , vol.275 , pp. 15466-15473
    • Nguyen, T.1    Huang, H.C.2    Pickett, C.B.3
  • 21
    • 84870572573 scopus 로고    scopus 로고
    • Bayesian inference
    • Bois FY. Bayesian inference. Methods Mol Biol 2013, 930:597-636.
    • (2013) Methods Mol Biol , vol.930 , pp. 597-636
    • Bois, F.Y.1
  • 22
    • 0035701428 scopus 로고    scopus 로고
    • Sensitivity analysis, Monte Carlo risk analysis, and Bayesian uncertainty assessment
    • Greenland S. Sensitivity analysis, Monte Carlo risk analysis, and Bayesian uncertainty assessment. Risk Anal 2001, 21:579-583.
    • (2001) Risk Anal , vol.21 , pp. 579-583
    • Greenland, S.1
  • 23
    • 84972492387 scopus 로고
    • Inference from iterative simulation using multiple sequences (with discussion)
    • Gelman A, Rubin DB. Inference from iterative simulation using multiple sequences (with discussion). Stat Sci 1992, 7:457-511.
    • (1992) Stat Sci , vol.7 , pp. 457-511
    • Gelman, A.1    Rubin, D.B.2
  • 24
    • 82655174039 scopus 로고    scopus 로고
    • Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes
    • Limonciel A, Aschauer L, Wilmes A, Prajczer S, Leonard MO, Pfaller W, Jennings P. Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes. Toxicol Vitro 2011, 25:1855-1862.
    • (2011) Toxicol Vitro , vol.25 , pp. 1855-1862
    • Limonciel, A.1    Aschauer, L.2    Wilmes, A.3    Prajczer, S.4    Leonard, M.O.5    Pfaller, W.6    Jennings, P.7
  • 25
    • 84898549151 scopus 로고    scopus 로고
    • Summarizing EC50 estimates from multiple dose-response experiments: a comparison of a meta-analysis strategy to a mixed-effects model approach
    • doi:10.1002/bimj.201300123. Epub ahead of print
    • Jiang X, Kopp-Schneider A. Summarizing EC50 estimates from multiple dose-response experiments: a comparison of a meta-analysis strategy to a mixed-effects model approach. Biom J 2014, doi:10.1002/bimj.201300123. Epub ahead of print.
    • (2014) Biom J
    • Jiang, X.1    Kopp-Schneider, A.2
  • 26
    • 84863304598 scopus 로고    scopus 로고
    • R Foundation for Statistical Computing, Vienna, Austria, R Core Team
    • R Core Team R: A Language and Environment for Statistical Computing 2012, R Foundation for Statistical Computing, http://www.R-project.org/, Vienna, Austria, R Core Team.
    • (2012) R: A Language and Environment for Statistical Computing
  • 29
    • 79960771381 scopus 로고    scopus 로고
    • Transporter-mediated drug-drug interactions
    • Muller F, Fromm MF. Transporter-mediated drug-drug interactions. Pharmacogenomics 2011, 12:1017-1037.
    • (2011) Pharmacogenomics , vol.12 , pp. 1017-1037
    • Muller, F.1    Fromm, M.F.2
  • 32
    • 0032784820 scopus 로고    scopus 로고
    • Losartan decreases plasma levels of TGF-beta1 in transplant patients with chronic allograft nephropathy
    • Campistol JM, Inigo P, Jimenez W, Lario S, Clesca PH, Oppenheimer F, Rivera F. Losartan decreases plasma levels of TGF-beta1 in transplant patients with chronic allograft nephropathy. Kidney Int 1999, 56:714-719.
    • (1999) Kidney Int , vol.56 , pp. 714-719
    • Campistol, J.M.1    Inigo, P.2    Jimenez, W.3    Lario, S.4    Clesca, P.H.5    Oppenheimer, F.6    Rivera, F.7
  • 33
    • 30144434323 scopus 로고    scopus 로고
    • TGF-beta1 expression in renal allograft rejection and cyclosporine A toxicity
    • Ozdemir BH, Ozdemir FN, Demirhan B, Haberal M. TGF-beta1 expression in renal allograft rejection and cyclosporine A toxicity. Transplantation 2005, 80:1681-1685.
    • (2005) Transplantation , vol.80 , pp. 1681-1685
    • Ozdemir, B.H.1    Ozdemir, F.N.2    Demirhan, B.3    Haberal, M.4
  • 35
    • 0344236406 scopus 로고    scopus 로고
    • Intracellular mechanisms of cyclosporin A-induced tubular cell apoptosis
    • Justo P, Lorz C, Sanz A, Egido J, Ortiz A. Intracellular mechanisms of cyclosporin A-induced tubular cell apoptosis. J Am Soc Nephrol 2003, 14:3072-3080.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 3072-3080
    • Justo, P.1    Lorz, C.2    Sanz, A.3    Egido, J.4    Ortiz, A.5
  • 36
    • 76449115656 scopus 로고    scopus 로고
    • Integrating multiple 'omics' analysis for microbial biology: application and methodologies
    • Zhang W, Li F, Nie L. Integrating multiple 'omics' analysis for microbial biology: application and methodologies. Microbiology 2010, 156:287-301.
    • (2010) Microbiology , vol.156 , pp. 287-301
    • Zhang, W.1    Li, F.2    Nie, L.3
  • 38
    • 71549116082 scopus 로고    scopus 로고
    • A proposed minimum skill set for university graduates to meet the informatics needs and challenges of the " -omics" era
    • Tan TW, Lim SJ, Khan AM, Ranganathan S. A proposed minimum skill set for university graduates to meet the informatics needs and challenges of the " -omics" era. BMC Genomics 2009, 10(Suppl 3):S36.
    • (2009) BMC Genomics , vol.10 , Issue.SUPPL. 3
    • Tan, T.W.1    Lim, S.J.2    Khan, A.M.3    Ranganathan, S.4
  • 39
    • 84872246574 scopus 로고    scopus 로고
    • A computational model to predict rat ovarian steroid secretion from in vitro experiments with endocrine disruptors
    • Quignot N, Bois FY. A computational model to predict rat ovarian steroid secretion from in vitro experiments with endocrine disruptors. PLoS One 2013, 8:e53891.
    • (2013) PLoS One , vol.8
    • Quignot, N.1    Bois, F.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.