Summarizing EC50 estimates from multiple dose-response experiments: A comparison of a meta-analysis strategy to a mixed-effects model approach

Biometrical Journal

Volumn 56, Issue 3, 2014, Pages 493-512

  Jiang, Xiaoqi ^a   Kopp Schneider, Annette ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Dose response analysis; EC50 estimate; Log logistic model; Meta analysis; Nonlinear mixed effects model

Indexed keywords

ANALYSIS STRATEGIES; DOSE RESPONSE; DOSE-RESPONSE ANALYSIS; EC50 ESTIMATE; LOG-LOGISTIC MODEL; META-ANALYSIS; MIXED EFFECTS MODELS; MULTIPLE-DOSE; NONLINEAR MIXED EFFECTS; NONLINEAR MIXED-EFFECT MODEL;

DODECYL SULFATE SODIUM;

3T3 CELL LINE; ANIMAL; BIOMETRY; COMPARATIVE STUDY; DOSE RESPONSE; LD 50; META ANALYSIS (TOPIC); MOUSE; PROCEDURES; STATISTICAL MODEL; TOXICITY; TOXICITY TESTING;

3T3 CELLS; ANIMALS; BIOMETRY; DOSE-RESPONSE RELATIONSHIP, DRUG; LETHAL DOSE 50; META-ANALYSIS AS TOPIC; MICE; MODELS, STATISTICAL; SODIUM DODECYL SULFATE; TOXICITY TESTS;

EID: 84898549151     PISSN: 03233847     EISSN: 15214036     Source Type: Journal    
DOI: 10.1002/bimj.201300123     Document Type: Article

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