TRF2-mediated stabilization of hREST4 is critical for the differentiation and maintenance of neural progenitors

Stem Cells

Volumn 32, Issue 8, 2014, Pages 2111-2122

  Ovando Roche, Patrick ^a   Yu, Jason S L ^a   Testori, Sarah ^a   Ho, Chloe ^a   Cui, Wei ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Human embryonic stem cells; Neural differentiation; Neural progenitor cells; REST REST4; Telomere repeat binding factor 2

Indexed keywords

HUMAN REPRESSOR ELEMENT 1 SILENCING TRANSCRIPTION FACTOR; MESSENGER RNA; TELOMERASE; TELOMERIC REPEAT BINDING FACTOR 1; TELOMERIC REPEAT BINDING FACTOR 2; TRANSCRIPTION FACTOR; UBIQUITIN; UNCLASSIFIED DRUG; RE1-SILENCING TRANSCRIPTION FACTOR; REPRESSOR PROTEIN; TERF2 PROTEIN, HUMAN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; EMBRYONIC STEM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; NEURAL STEM CELL; PHENOTYPE; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN STABILITY; RNA SEQUENCE; UPREGULATION; CELL LINE; CYTOLOGY; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC TRANSDUCTION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; METABOLISM; NERVOUS SYSTEM DEVELOPMENT; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CELL DIFFERENTIATION; CELL LINE; EMBRYONIC STEM CELLS; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; NEURAL STEM CELLS; NEUROGENESIS; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TELOMERIC REPEAT BINDING PROTEIN 2; TRANSDUCTION, GENETIC; UP-REGULATION;

EID: 84902778807     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1725     Document Type: Article

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