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Volumn 5, Issue , 2014, Pages

Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL N TYPE; FRAGILE X MENTAL RETARDATION PROTEIN; PROTEASOME; SHORT HAIRPIN RNA; CALCIUM;

EID: 84902601046     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4628     Document Type: Article
Times cited : (108)

References (55)
  • 1
    • 53849110899 scopus 로고    scopus 로고
    • Fragile X syndrome: Loss of local mRNA regulation alters synaptic development and function
    • Bassell, G. J. & Warren, S. T. Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function. Neuron 60, 201-214 (2008).
    • (2008) Neuron , vol.60 , pp. 201-214
    • Bassell, G.J.1    Warren, S.T.2
  • 2
    • 84862637069 scopus 로고    scopus 로고
    • The pathophysiology of fragile X (and what it teaches us about synapses)
    • Bhakar, A. L., Dolen, G. & Bear, M. F. The pathophysiology of fragile X (and what it teaches us about synapses). Annu. Rev. Neurosci. 35, 417-443 (2012).
    • (2012) Annu. Rev. Neurosci. , vol.35 , pp. 417-443
    • Bhakar, A.L.1    Dolen, G.2    Bear, M.F.3
  • 3
    • 44449121279 scopus 로고    scopus 로고
    • A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome
    • Dictenberg, J. B., Swanger, S. A., Antar, L. N., Singer, R. H. & Bassell, G. J. A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. Dev. Cell 14, 926-939 (2008).
    • (2008) Dev. Cell , vol.14 , pp. 926-939
    • Dictenberg, J.B.1    Swanger, S.A.2    Antar, L.N.3    Singer, R.H.4    Bassell, G.J.5
  • 4
    • 0037423293 scopus 로고    scopus 로고
    • The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses
    • Zalfa, F. et al. The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses. Cell 112, 317-327 (2003).
    • (2003) Cell , vol.112 , pp. 317-327
    • Zalfa, F.1
  • 5
    • 79958045841 scopus 로고    scopus 로고
    • Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling
    • Muddashetty, R. S. et al. Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling. Mol. Cell 42, 673-688 (2011).
    • (2011) Mol. Cell , vol.42 , pp. 673-688
    • Muddashetty, R.S.1
  • 6
    • 3042647610 scopus 로고    scopus 로고
    • The mGluR theory of fragile X mental retardation
    • Bear, M. F., Huber, K. M. & Warren, S. T. The mGluR theory of fragile X mental retardation. Trends Neurosci. 27, 370-377 (2004).
    • (2004) Trends Neurosci. , vol.27 , pp. 370-377
    • Bear, M.F.1    Huber, K.M.2    Warren, S.T.3
  • 7
    • 0035977134 scopus 로고    scopus 로고
    • Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function
    • Zhang, Y. Q. et al. Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function. Cell 107, 591-603 (2001).
    • (2001) Cell , vol.107 , pp. 591-603
    • Zhang, Y.Q.1
  • 8
    • 50649095000 scopus 로고    scopus 로고
    • Temporal requirements of the fragile X mental retardation protein in the regulation of synaptic structure
    • Gatto, C. L. & Broadie, K. Temporal requirements of the fragile X mental retardation protein in the regulation of synaptic structure. Development 135, 2637-2648 (2008).
    • (2008) Development , vol.135 , pp. 2637-2648
    • Gatto, C.L.1    Broadie, K.2
  • 9
    • 79960779323 scopus 로고    scopus 로고
    • FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism
    • Darnell, J. C. et al. FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell 146, 247-261 (2011).
    • (2011) Cell , vol.146 , pp. 247-261
    • Darnell, J.C.1
  • 10
    • 79960955668 scopus 로고    scopus 로고
    • Abnormal presynaptic short-term plasticity and information processing in a mouse model of fragile X syndrome
    • Deng, P. Y., Sojka, D. & Klyachko, V. a. Abnormal presynaptic short-term plasticity and information processing in a mouse model of fragile X syndrome. J. Neurosci. 31, 10971-10982 (2011).
    • (2011) J. Neurosci. , vol.31 , pp. 10971-10982
    • Deng, P.Y.1    Sojka, D.2    Klyachko, V.A.3
  • 11
    • 84864153599 scopus 로고    scopus 로고
    • Calcium channel auxiliary alpha2delta and beta subunits: Trafficking and one step beyond
    • Dolphin, A. C. Calcium channel auxiliary alpha2delta and beta subunits: trafficking and one step beyond. Nat. Rev. Neurosci. 13, 542-555 (2012).
    • (2012) Nat. Rev. Neurosci. , vol.13 , pp. 542-555
    • Dolphin, A.C.1
  • 12
    • 0023874003 scopus 로고
    • Dominant role of N-type Ca2+ channels in evoked release of norepinephrine from sympathetic neurons
    • Hirning, L. D. et al. Dominant role of N-type Ca2+ channels in evoked release of norepinephrine from sympathetic neurons. Science 239, 57-61 (1988).
    • (1988) Science , vol.239 , pp. 57-61
    • Hirning, L.D.1
  • 13
    • 0027340695 scopus 로고
    • Multiple Ca2+ channel types coexist to regulate synaptosomal neurotransmitter release
    • Turner, T. J., Adams, M. E. & Dunlap, K. Multiple Ca2+ channel types coexist to regulate synaptosomal neurotransmitter release. Proc. Natl Acad. Sci. USA 90, 9518-9522 (1993).
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 9518-9522
    • Turner, T.J.1    Adams, M.E.2    Dunlap, K.3
  • 14
    • 52049098700 scopus 로고    scopus 로고
    • Calcium channel regulation and presynaptic plasticity
    • Catterall, W. A. & Few, A. P. Calcium channel regulation and presynaptic plasticity. Neuron 59, 882-901 (2008).
    • (2008) Neuron , vol.59 , pp. 882-901
    • Catterall, W.A.1    Few, A.P.2
  • 15
    • 77954145556 scopus 로고    scopus 로고
    • Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack
    • Brown, M. R. et al. Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack. Nat. Neurosci. 13, 819-821 (2010).
    • (2010) Nat. Neurosci. , vol.13 , pp. 819-821
    • Brown, M.R.1
  • 16
    • 84874256375 scopus 로고    scopus 로고
    • FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels
    • Deng, P. Y. et al. FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels. Neuron 77, 696-711 (2013).
    • (2013) Neuron , vol.77 , pp. 696-711
    • Deng, P.Y.1
  • 17
    • 0022413083 scopus 로고
    • Three types of neuronal calcium channel with different calcium agonist sensitivity
    • Nowycky, M. C., Fox, A. P. & Tsien, R. W. Three types of neuronal calcium channel with different calcium agonist sensitivity. Nature 316, 440-443 (1985).
    • (1985) Nature , vol.316 , pp. 440-443
    • Nowycky, M.C.1    Fox, A.P.2    Tsien, R.W.3
  • 18
    • 84861596955 scopus 로고    scopus 로고
    • Chronic pregabalin inhibits synaptic transmission between rat dorsal root ganglion and dorsal horn neurons in culture
    • Hendrich, J., Bauer, C. S. & Dolphin, A. C. Chronic pregabalin inhibits synaptic transmission between rat dorsal root ganglion and dorsal horn neurons in culture. Channels (Austin.) 6, 124-132 (2012).
    • (2012) Channels (Austin.) , vol.6 , pp. 124-132
    • Hendrich, J.1    Bauer, C.S.2    Dolphin, A.C.3
  • 19
    • 20444379206 scopus 로고    scopus 로고
    • Gprotein-gated inhibitory module of N-type (ca(v)2.2) ca2+ channels
    • Agler, H. L. et al. G protein-gated inhibitory module of N-type (ca(v)2.2) ca2+ channels. Neuron 46, 891-904 (2005).
    • (2005) Neuron , vol.46 , pp. 891-904
    • Agler, H.L.1
  • 20
    • 79251585466 scopus 로고    scopus 로고
    • The cavbeta subunit prevents RFP2-mediated ubiquitination and proteasomal degradation of L-type channels
    • Altier, C. et al. The Cavbeta subunit prevents RFP2-mediated ubiquitination and proteasomal degradation of L-type channels. Nat. Neurosci. 14, 173-180 (2011).
    • (2011) Nat. Neurosci. , vol.14 , pp. 173-180
    • Altier, C.1
  • 21
    • 79953190397 scopus 로고    scopus 로고
    • Beta-subunits promote the expression of Ca(V)2.2 channels by reducing their proteasomal degradation
    • Waithe, D., Ferron, L., Page, K. M., Chaggar, K. & Dolphin, A. C. Beta-subunits promote the expression of Ca(V)2.2 channels by reducing their proteasomal degradation. J. Biol. Chem. 286, 9598-9611 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 9598-9611
    • Waithe, D.1    Ferron, L.2    Page, K.M.3    Chaggar, K.4    Dolphin, A.C.5
  • 22
    • 23044516268 scopus 로고    scopus 로고
    • Interaction via a key tryptophan in the I-II linker of N-type calcium channels is required for beta1 but not for palmitoylated beta2, implicating an additional binding site in the regulation of channel voltagedependent properties
    • Leroy, J. et al. Interaction via a key tryptophan in the I-II linker of N-type calcium channels is required for beta1 but not for palmitoylated beta2, implicating an additional binding site in the regulation of channel voltagedependent properties. J. Neurosci. 25, 6984-6996 (2005).
    • (2005) J. Neurosci. , vol.25 , pp. 6984-6996
    • Leroy, J.1
  • 23
    • 37549044298 scopus 로고    scopus 로고
    • FMRP phosphorylation reveals an immediate-early signaling pathway triggered by group I mGluR and mediated by PP2A
    • Narayanan, U. et al. FMRP phosphorylation reveals an immediate-early signaling pathway triggered by group I mGluR and mediated by PP2A. J. Neurosci. 27, 14349-14357 (2007).
    • (2007) J. Neurosci. , vol.27 , pp. 14349-14357
    • Narayanan, U.1
  • 24
    • 38449091182 scopus 로고    scopus 로고
    • Decreased nociceptive sensitization in mice lacking the fragile X mental retardation protein: Role of mGluR1/5 and mTOR
    • Price, T. J. et al. Decreased nociceptive sensitization in mice lacking the fragile X mental retardation protein: role of mGluR1/5 and mTOR. J. Neurosci. 27, 13958-13967 (2007).
    • (2007) J. Neurosci. , vol.27 , pp. 13958-13967
    • Price, T.J.1
  • 25
    • 0028595727 scopus 로고
    • Identification of a syntaxin-binding site on N-type calcium channels
    • Sheng, Z. H., Rettig, J., Takahashi, M. & Catterall, W. A. Identification of a syntaxin-binding site on N-type calcium channels. Neuron 13, 1303-1313 (1994).
    • (1994) Neuron , vol.13 , pp. 1303-1313
    • Sheng, Z.H.1    Rettig, J.2    Takahashi, M.3    Catterall, W.A.4
  • 26
    • 84861947988 scopus 로고    scopus 로고
    • Alpha2delta expression sets presynaptic calcium channel abundance and release probability
    • Hoppa, M. B., Lana, B., Margas, W., Dolphin, A. C. & Ryan, T. A. Alpha2delta expression sets presynaptic calcium channel abundance and release probability. Nature 486, 122-125 (2012).
    • (2012) Nature , vol.486 , pp. 122-125
    • Hoppa, M.B.1    Lana, B.2    Margas, W.3    Dolphin, A.C.4    Ryan, T.A.5
  • 27
    • 0033786834 scopus 로고    scopus 로고
    • Real-time measurements of vesicle-SNARE recycling in synapses of the central nervous system
    • Sankaranarayanan, S. & Ryan, T. A. Real-time measurements of vesicle-SNARE recycling in synapses of the central nervous system. Nat. Cell Biol. 2, 197-204 (2000).
    • (2000) Nat. Cell Biol. , vol.2 , pp. 197-204
    • Sankaranarayanan, S.1    Ryan, T.A.2
  • 28
    • 77954858360 scopus 로고    scopus 로고
    • Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome
    • Suvrathan, A., Hoeffer, C. A., Wong, H., Klann, E. & Chattarji, S. Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome. Proc. Natl Acad. Sci. USA 107, 11591-11596 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 11591-11596
    • Suvrathan, A.1    Hoeffer, C.A.2    Wong, H.3    Klann, E.4    Chattarji, S.5
  • 29
    • 84873282879 scopus 로고    scopus 로고
    • A target cellspecific role for presynaptic Fmr1 in regulating glutamate release onto neocortical fast-spiking inhibitory neurons
    • Patel, A. B., Hays, S. A., Bureau, I., Huber, K. M. & Gibson, J. R. A target cellspecific role for presynaptic Fmr1 in regulating glutamate release onto neocortical fast-spiking inhibitory neurons. J. Neurosci. 33, 2593-2604 (2013).
    • (2013) J. Neurosci. , vol.33 , pp. 2593-2604
    • Patel, A.B.1    Hays, S.A.2    Bureau, I.3    Huber, K.M.4    Gibson, J.R.5
  • 30
    • 0030273248 scopus 로고    scopus 로고
    • Inhibition of neurotransmission by peptides containing the synaptic protein interaction site of N-type Ca2+ channels
    • Mochida, S., Sheng, Z. H., Baker, C., Kobayashi, H. & Catterall, W. A. Inhibition of neurotransmission by peptides containing the synaptic protein interaction site of N-type Ca2+ channels. Neuron 17, 781-788 (1996).
    • (1996) Neuron , vol.17 , pp. 781-788
    • Mochida, S.1    Sheng, Z.H.2    Baker, C.3    Kobayashi, H.4    Catterall, W.A.5
  • 31
    • 0035980145 scopus 로고    scopus 로고
    • Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin
    • Coppola, T. et al. Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin. J. Biol. Chem. 276, 32756-32762 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 32756-32762
    • Coppola, T.1
  • 32
    • 0345269761 scopus 로고    scopus 로고
    • Requirement for the synaptic protein interaction site for reconstitution of synaptic transmission by P/Q-type calcium channels
    • Mochida, S. et al. Requirement for the synaptic protein interaction site for reconstitution of synaptic transmission by P/Q-type calcium channels. Proc. Natl Acad. Sci. USA 100, 2819-2824 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 2819-2824
    • Mochida, S.1
  • 33
    • 33747199564 scopus 로고    scopus 로고
    • Role of the synprint site in presynaptic targeting of the calcium channel CaV2.2 in hippocampal neurons
    • Szabo, Z., Obermair, G. J., Cooper, C. B., Zamponi, G. W. & Flucher, B. E. Role of the synprint site in presynaptic targeting of the calcium channel CaV2.2 in hippocampal neurons. Eur. J. Neurosci. 24, 709-718 (2006).
    • (2006) Eur. J. Neurosci. , vol.24 , pp. 709-718
    • Szabo, Z.1    Obermair, G.J.2    Cooper, C.B.3    Zamponi, G.W.4    Flucher, B.E.5
  • 34
    • 0028783997 scopus 로고
    • Functional impact of syntaxin on gating of N-type and Q-type calcium channels
    • Bezprozvanny, I., Scheller, R. H. & Tsien, R. W. Functional impact of syntaxin on gating of N-type and Q-type calcium channels. Nature 378, 623-626 (1995).
    • (1995) Nature , vol.378 , pp. 623-626
    • Bezprozvanny, I.1    Scheller, R.H.2    Tsien, R.W.3
  • 35
    • 0040962408 scopus 로고    scopus 로고
    • Association of neuronal calcium channels with modular adaptor proteins
    • Maximov, A., Sudhof, T. C. & Bezprozvanny, I. Association of neuronal calcium channels with modular adaptor proteins. J. Biol. Chem. 274, 24453-24456 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 24453-24456
    • Maximov, A.1    Sudhof, T.C.2    Bezprozvanny, I.3
  • 36
    • 78651509693 scopus 로고    scopus 로고
    • RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction
    • Kaeser, P. S. et al. RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction. Cell 144, 282-295 (2011).
    • (2011) Cell , vol.144 , pp. 282-295
    • Kaeser, P.S.1
  • 37
    • 84876919334 scopus 로고    scopus 로고
    • Regulation of Ca(V)2 calcium channels by G protein coupled receptors
    • Zamponi, G. W. & Currie, K. P. Regulation of Ca(V)2 calcium channels by G protein coupled receptors. Biochim. Biophys. Acta 1828, 1629-1643 (2013).
    • (2013) Biochim. Biophys. Acta , vol.1828 , pp. 1629-1643
    • Zamponi, G.W.1    Currie, K.P.2
  • 38
    • 29444450427 scopus 로고    scopus 로고
    • ORL1 receptor-mediated internalization of N-type calcium channels
    • Altier, C. et al. ORL1 receptor-mediated internalization of N-type calcium channels. Nat. Neurosci. 9, 31-40 (2006).
    • (2006) Nat. Neurosci. , vol.9 , pp. 31-40
    • Altier, C.1
  • 39
    • 43449115080 scopus 로고    scopus 로고
    • D1 receptors physically interact with N-type calcium channels to regulate channel distribution and dendritic calcium entry
    • Kisilevsky, A. E. et al. D1 receptors physically interact with N-type calcium channels to regulate channel distribution and dendritic calcium entry. Neuron 58, 557-570 (2008).
    • (2008) Neuron , vol.58 , pp. 557-570
    • Kisilevsky, A.E.1
  • 40
    • 33644799748 scopus 로고    scopus 로고
    • The structure of the N-terminal domain of the fragile X mental retardation protein: A platform for protein-protein interaction
    • Ramos, A. et al. The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction. Structure. 14, 21-31 (2006).
    • (2006) Structure , vol.14 , pp. 21-31
    • Ramos, A.1
  • 41
    • 4644366904 scopus 로고    scopus 로고
    • The C terminus of fragile X mental retardation protein interacts with the multi-domain Ran-binding protein in the microtubule-organising centre
    • Menon, R. P., Gibson, T. J. & Pastore, A. The C terminus of fragile X mental retardation protein interacts with the multi-domain Ran-binding protein in the microtubule-organising centre. J. Mol. Biol. 343, 43-53 (2004).
    • (2004) J. Mol. Biol. , vol.343 , pp. 43-53
    • Menon, R.P.1    Gibson, T.J.2    Pastore, A.3
  • 42
    • 84860903793 scopus 로고    scopus 로고
    • Role of Ran BP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain
    • Lakshmana, M. K. et al. Role of Ran BP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain. FASEB J. 26, 2072-2083 (2012).
    • (2012) FASEB J. , vol.26 , pp. 2072-2083
    • Lakshmana, M.K.1
  • 43
    • 0035892242 scopus 로고    scopus 로고
    • Presynaptic Ca2+-activated K+ channels in glutamatergic hippocampal terminals and their role in spike repolarization and regulation of transmitter release
    • Hu, H. et al. Presynaptic Ca2+-activated K+ channels in glutamatergic hippocampal terminals and their role in spike repolarization and regulation of transmitter release. J. Neurosci. 21, 9585-9597 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 9585-9597
    • Hu, H.1
  • 47
    • 0023159073 scopus 로고
    • Calcium channel currents and their inhibition by (-)-baclofen in rat sensory neurones: Modulation by guanine nucleotides
    • Dolphin, A. C. & Scott, R. H. Calcium channel currents and their inhibition by (-)-baclofen in rat sensory neurones: modulation by guanine nucleotides. J. Physiol. 386, 1-17 (1987).
    • (1987) J. Physiol. , vol.386 , pp. 1-17
    • Dolphin, A.C.1    Scott, R.H.2
  • 48
    • 84866628742 scopus 로고    scopus 로고
    • Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: A randomized, controlled, phase 2 trial
    • Berry-Kravis, E. M. et al. Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial. Sci. Transl. Med. 4, 152ra127 (2012).
    • (2012) Sci. Transl. Med. , vol.4 , pp. 152ra127
    • Berry-Kravis, E.M.1
  • 49
    • 84879191741 scopus 로고    scopus 로고
    • Calcium ion channels: Challenges and successes in drug discovery
    • McDonough, S. I. Calcium ion channels: challenges and successes in drug discovery. WIREs Membr. Transp. Signal. 2, 85-104 (2013).
    • (2013) WIREs Membr. Transp. Signal. , vol.2 , pp. 85-104
    • McDonough, S.I.1
  • 50
    • 54849412901 scopus 로고    scopus 로고
    • The stargazin-related protein gamma 7 interacts with the mRNA-binding protein heterogeneous nuclear ribonucleoprotein A2 and regulates the stability of specific mRNAs, including CaV2.2
    • Ferron, L. et al. The stargazin-related protein gamma 7 interacts with the mRNA-binding protein heterogeneous nuclear ribonucleoprotein A2 and regulates the stability of specific mRNAs, including CaV2.2. J. Neurosci. 28, 10604-10617 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 10604-10617
    • Ferron, L.1
  • 51
    • 75949101467 scopus 로고    scopus 로고
    • Regulation of synaptic structure and function by FMRPassociated micro RNAs miR-125b and miR-132
    • Edbauer, D. et al. Regulation of synaptic structure and function by FMRPassociated micro RNAs miR-125b and miR-132. Neuron 65, 373-384 (2010).
    • (2010) Neuron , vol.65 , pp. 373-384
    • Edbauer, D.1
  • 52
    • 0035503078 scopus 로고    scopus 로고
    • Dominant-negative synthesis suppression of voltage-gated calcium channel Cav2.2 induced by truncated constructs
    • Raghib, A. et al. Dominant-negative synthesis suppression of voltage-gated calcium channel Cav2.2 induced by truncated constructs. J. Neurosci. 21, 8495-8504 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 8495-8504
    • Raghib, A.1
  • 53
    • 34247849440 scopus 로고    scopus 로고
    • New transmembrane AMPA receptor regulatory protein isoform, gamma-7, differentially regulates AMPA receptors
    • Kato, A. S. et al. New transmembrane AMPA receptor regulatory protein isoform, gamma-7, differentially regulates AMPA receptors. J. Neurosci. 27, 4969-4977 (2007).
    • (2007) J. Neurosci. , vol.27 , pp. 4969-4977
    • Kato, A.S.1
  • 54
    • 0019229699 scopus 로고
    • The variance of sodium current fluctuations at the node of Ranvier
    • Sigworth, F. J. The variance of sodium current fluctuations at the node of Ranvier. J. Physiol. 307, 97-129 (1980).
    • (1980) J. Physiol. , vol.307 , pp. 97-129
    • Sigworth, F.J.1
  • 55
    • 0028169761 scopus 로고
    • Omega-conotoxin block of N-type calcium channels in frog and rat sympathetic neurons
    • Boland, L. M., Morrill, J. A. & Bean, B. P. Omega-conotoxin block of N-type calcium channels in frog and rat sympathetic neurons. J. Neurosci. 14, 5011-5027 (1994).
    • (1994) J. Neurosci. , vol.14 , pp. 5011-5027
    • Boland, L.M.1    Morrill, J.A.2    Bean, B.P.3


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