Involvement of oxidative stress associated with glutathione depletion and p38 mitogen-activated protein kinase activation in arsenic disulfide-induced differentiation in HL-60 cells

Leukemia and Lymphoma

Volumn 55, Issue 2, 2014, Pages 392-404

  Hu, Xiao Mei ^a,b   Yuan, Bo ^a   Tanaka, Sachiko ^a   Zhou, Qingbing ^a   Onda, Kenji ^a   Toyoda, Hiroo ^a   Hirano, Toshihiko ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b XIYUAN HOSPITAL   (China)

Author keywords

Arsenic disulfide; Cell differentiation; HL 60 cells; Oxidative stress; P38 MAPK activation

Indexed keywords

ARSENIC ACID DERIVATIVE; ARSENIC DISULFIDE; CD11B ANTIGEN; GLUTATHIONE; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; NITROBLUE TETRAZOLIUM; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL SIZE; CONTROLLED STUDY; CORRELATIONAL STUDY; ENZYME ACTIVATION; HL 60 CELL LINE; LEUKEMIA CELL; LEUKEMIA CELL LINE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION;

ANTIGENS, CD11B; APOPTOSIS; ARSENICALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; FLOW CYTOMETRY; GLUTATHIONE; HL-60 CELLS; HUMANS; IMIDAZOLES; MEMBRANE POTENTIAL, MITOCHONDRIAL; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; REACTIVE OXYGEN SPECIES; SULFIDES;

EID: 84902592989     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2013.802779     Document Type: Article

References (35)

1. Miller WH J.r., Schipper HM, Lee J.S., et al Mechanisms of action of arsenic trioxide. Cancer Res 2002;62:3893-3903. (Pubitemid 34792653)
2. Srdan V, Francis G, Alfonso Q.C., et al Arsenic derivatives in hematologic malignancies: a role beyond acute promyelocytic leukemia? Hematol Oncol 2006;24:181-188.
3. Cohen SM, Arnold LL, Eldan M, et al Methylated arsenicals: the implications of metabolism and carcinogenicity studies In rodents to human risk assessment. Crit Rev Toxicol 2006, 36:99-133.
4. Hu XM, Ma L, Hu N.P., et al Ai-Lin I (As###2#### O###3####)treated 62 cases of acute promyelocytic leukemia (in Chinese). Chin J Integr Chin West Med 1999;19:473-476.
5. Wang ZY, Chen Z. Acute promyelocytc leukemia: from highly fatal to highly curable. Blood 2008;111:2505-2515.
6. Hu XM, Hirano T, Oka K. Arsenic trioxide induces apoptosis in cells of MOLT-4 and its daunorubicin-resistant cell line via depletion of intracellular glutathione, disruption of mitochondrial membrane potential and activation of caspase-3. Cancer Chemother Pharmacol 2003;52:47-58. (Pubitemid 36920628)
7. Gan G, Sun J, Wang J.Y., et al Analysis of 27 cases on serious adverse drug reaction induced by arsenic trioxide. Chin J Pharmacovig 2008;5:286-290.
8. Wu JZ, Shao YB, Liu J.L., et al The medicinal use of realgar (As###4####S###4####) and its recent development as an anticancer agent. J Ethnopharmacol 2011;135:595-602.
9. Hu XM, Mu R, Xu Y.G., et al Treatment of hematologic malignancies with qinghuang powder. Int J Trad Chin Med 2011;33:568-570.
10. Han YH, Moon HJ, You B.R., et al The effect of MAPK inhibitors on arsenic trioxide-treated calu-6 lung cells in relation to cell death, ROS and GSH levels. Anticancer Res 2009;29:3837-3844.
11. Ho SY, Wu WJ, Chiu H.W., et al Arsenic trioxide and radiation enhance apoptotic effects in HL-60 cells through increased ROS generation and regulation of JNK and p38 MAPK signaling pathways. Chem Biol Interact 2011;192:162-171.
12. Giafis N, Katsoulidis E, Sassano A., et al Role of the p38 mitogen-activated protein kinase pathway in the generation of arsenic trioxide-dependent cellular responses. Cancer Res 2006;66:6763-6771. (Pubitemid 44085635)
13. Kang YH, Lee SJ The role of p38 MAPK and INK in arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells. J Cell Physiol 2008;217:23-33.
14. Platanias LC. Map kinase signaling pathways and hematologic malignancies. Blood 2003;101:4667-4679. (Pubitemid 36857719)
15. Li JE, Wu WL, Wang Z.Y., et al Apoptotic effect of As2S2 on K562 cells and its mechanism. Acta Pharmacol Sin 2002;23:991-996.
16. Wu JZ, Ho PC Evaluation of the in vitro activity and in vivo bioavailability of realgar nanoparticles prepared by cryo-grinding. Eur J Pharm Sci 2006;29:35-44. (Pubitemid 44279395)
17. Tse WP, Cheng CHK, Che CT, et al Realgar-mediated growth inhibition on HaCaT human keratinocytes is associated with induction of apoptosis. Int J Mol Med 2009;24:189-196.
18. Wang LW, Shi YL, Wang N, et al Association of oxidative stress with realgar-induced differentiation in human leukemia HL-60 cells. Chemotherapy 2009;55:460-467.
19. Luo LY, Huang J, Gou B.D., et al Induction of human promyelocytic leukemia HL-60 cell differentiation into monocytes by arsenic sulphide: involvement of serine/threonine protein phosphatases. Leuk Res 2006;30:1399-1405. (Pubitemid 44316859)
20. Lu JJ, Meng LH, Cai Y.J., et al Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species. Cancer Biol Ther 2008;7; 1017-1023.
21. Yuan B, Ohyama K, Takeichi M., et al Direct contribution of inducible nitric oxide synthase expression to apoptosis induction in primary smooth chorion trophoblast cells of human fetal membrane tissues. Int J Biochem Cell Biol 2009;41:1062-1069.
22. Yamamoto T, Sakaguchi N, Hachiya M., et al Role of catalase in monocytic differentiation of U937 cells by TPA: hydrogen peroxide as a second messenger. Leukemia 2009;23:761-769.
23. Hu XM, Hirano T, Oka K. Arsenic trioxide induces apoptosis equally in T lymphoblastoid leukemia MOLT-4 cells and P-gp-expressing daunorubicin-resistant MOLT-4 cells. Cancer Chemother Pharmacol 2003;52:119-126. (Pubitemid 36259471)
24. Drayson MT, Michell RH, Jennifer D, et al Cell proliferation and CDllb expression are controlled independently during HL 60 cells differentiation initiated by 1,25a-dihydroxyvitamin D3 or all-trans-retinonic acid. Exp Cell Res 2001;266:126-134. (Pubitemid 32989049)
25. Miaoqing Shen M.Q., Yen A. Nicotinamide cooperates with retinoic acid and 1,25-dihydroxyvitamin D3 to regulate cell differentiation and cell cycle arrest of human myeloblasts leukemia cells. Oncology 2009;76:91-100.
26. Yuksel S, Saydama G, Uslu R., et al Arsenic trioxide and methylprednisolone use different signal transduction pathways in leukemia differentiation. Leuk Res 2002;26:391-398. (Pubitemid 34143054)
27. Wang N, Wang LW, Gou B.D., et al Realgar-induced differentiation is associated with MAPK pathways In HL-60 cells. Cell Biol Int 2008;32:1497-1505.
28. Zou YE Niu PY, Yang J, et al The JNK signaling pathway is involved in sodium-selenite-induced apoptosis mediated by reactive oxygen in HepG2 cells. Cancer Biol Ther 2008;7:691-698. (Pubitemid 351847003)
29. Valko M, Leibfritz D, Moncol J., et al Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007;39:44-48.
30. Matsuzawa A, Ichijo H. Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling. Biochim Biophys Acta 2008;1780:1325-1336.
31. Sánchez Y., Amrán D, Fernández C, et al. Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38-MAPK, AMPK). Int J Cancer 2008;23:1205-1214.
32. Ichijo H, Nishida E, Irie K., et al Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 1997;275:90-94. (Pubitemid 27020316)
33. Juretic N, Santibanez JF, Hurtado C, et al ERK 1, 2 and p38 pathways are involved in the proliferative stimuli mediated by urokinase in osteoblastic SaOS-2 cell line. J Cell Biochem 2001;83:92-98.
34. Bras M, Queenan B, Susin SA Programmed cell death via mitochondria: different modes of dying. Biochemistry 2005;70:231-239. (Pubitemid 40512332)
35. Blagosklonny MV. Unwinding the loop of Bcl-2 phosphorylation. Leukemia 2001;15:869-874. (Pubitemid 32529885)