Licochalcone A, a natural chalconoid isolated from Glycyrrhiza inflata root, induces apoptosis via Sp1 and Sp1 regulatory proteins in oral squamous cell carcinoma

International Journal of Oncology

Volumn 45, Issue 2, 2014, Pages 667-674

  Cho, Jung Jae ^a   Chae, Jung Il ^b   Yoon, Goo ^a   Kim, Ka Hwi ^a   Cho, Jin Hyoung ^b   Cho, Seung Sik ^a   Cho, Young Sik ^c   Shim, Jung Hyun ^a  

^a Mokpo National University   (South Korea)

^b Chonbuk National University   (South Korea)

^c Keimyung University   (South Korea)

Author keywords

Apoptosis; Licochalcone A; Oral squamous cell carcinoma; Specificity protein 1

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CHALCONE DERIVATIVE; LICOCHALCONE A; LIPOCORTIN 5; PROTEIN BAX; PROTEIN BCL XL; PROTEIN BID; TRANSCRIPTION FACTOR SP1; APOPTOSIS REGULATORY PROTEIN; PLANT EXTRACT; SP1 PROTEIN, HUMAN;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL LINE; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER SURVIVAL; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; GLYCYRRHIZA; GLYCYRRHIZA INFLATA; HUMAN; HUMAN CELL; IC 50; MOUTH SQUAMOUS CELL CARCINOMA; MTS ASSAY; PLANT ROOT; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT OUTCOME; WESTERN BLOTTING; DRUG EFFECTS; METABOLISM; MOUTH TUMOR; PATHOLOGY; PHYTOTHERAPY; PROCEDURES; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CHALCONES; GLYCYRRHIZA; HUMANS; MOUTH NEOPLASMS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SP1 TRANSCRIPTION FACTOR;

EID: 84902584264     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2014.2461     Document Type: Article

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