Molecular pathology of brain matrix metalloproteases, claudin5, and aquaporins in forensic autopsy cases with special regard to methamphetamine intoxication

International Journal of Legal Medicine

Volumn 128, Issue 3, 2014, Pages 469-474

  Wang, Qi ^a,b   Ishikawa, Takaki ^b,c   Michiue, Tomomi ^b   Zhu, Bao Li ^d   Guan, Da Wei ^d   Maeda, Hitoshi ^b  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c TOTTORI UNIVERSITY   (Japan)

^d CHINA MEDICAL UNIVERSITY   (China)

Author keywords

AQPs; CLDN5; Forensic molecular pathology; Methamphetamine intoxication; MMPs

Indexed keywords

AQUAPORIN 1; AQUAPORIN 4; CLAUDIN 5; CLDN5 PROTEIN, HUMAN; GELATINASE A; GELATINASE B; HYPNOTIC SEDATIVE AGENT; MESSENGER RNA; METHAMPHETAMINE; NARCOTIC AGENT; PHENOBARBITAL;

ADOLESCENT; ADULT; AGED; ASPHYXIA; BRAIN; BRAIN INJURY; CARBON MONOXIDE INTOXICATION; FEMALE; FORENSIC PATHOLOGY; FORENSIC TOXICOLOGY; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MIDDLE AGED; MORTALITY; PENETRATING TRAUMA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AQUAPORIN 1; AQUAPORIN 4; ASPHYXIA; BRAIN; BRAIN INJURIES; CARBON MONOXIDE POISONING; CLAUDIN-5; FEMALE; FORENSIC PATHOLOGY; FORENSIC TOXICOLOGY; HUMANS; HYPNOTICS AND SEDATIVES; IMMUNOHISTOCHEMISTRY; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; METHAMPHETAMINE; MIDDLE AGED; NARCOTICS; PHENOBARBITAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; WOUNDS, PENETRATING; YOUNG ADULT;

EID: 84902545711     PISSN: 09379827     EISSN: 14371596     Source Type: Journal    
DOI: 10.1007/s00414-014-0972-6     Document Type: Article

References (39)

1. Halpin LE, Collins SA, Yamamoto BK (2013) Neurotoxicity of methamphetamine and 3,4-methylenedioxymethamphetamine. Life Sci
2. Martins T, Baptista S, Goncalves J, Leal E, Milhazes N, Borges F, Ribeiro CF, Quintela O, Lendoiro E, Lopez-Rivadulla M, Ambrosio AF, Silva AP (2011) Methamphetamine transiently increases the blood-brain barrier permeability in the hippocampus: role of tight junction proteins and matrix metalloproteinase-9. Brain Res 1411:28-40
3. Sharma HS, Kiyatkin EA (2009) Rapid morphological brain abnormalities during acute methamphetamine intoxication in the rat: an experimental study using light and electron microscopy. J Chem Neuroanat 37(1):18-32
4. Woessner JF Jr (1994) The family of matrix metalloproteinases. Ann N Y Acad Sci 732:11-21
5. Agrawal SM, Lau L, Yong VW (2008) MMPs in the central nervous system: where the good guys go bad. Semin Cell Dev Biol 19(1):42-51
6. Furuse M, Tsukita S (2006) Claudins in occluding junctions of humans and flies. Trends Cell Biol 16(4):181-188
7. Zador Z, Bloch O, Yao X, Manley GT (2007) Aquaporins: role in cerebral edema and brain water balance. Prog Brain Res 161:185-194
8. Wang Q, Ishikawa T, Michiue T, Zhu BL, Guan DW, Maeda H (2013) Molecular pathology of brain edema after severe burns in forensic autopsy cases with special regard to the importance of reference gene selection. Int J Legal Med 127(5):881-889
9. Wang Q, Ishikawa T, Michiue T, Zhu BL, Maeda H (2011) Evaluation of human brain damage in fire fatality by quantification of basic fibroblast growth factor (bFGF), glial fibrillary acidic protein (GFAP) and single-stranded DNA (ssDNA) immunoreactivities. Forensic Sci Int 211(1-3):19-26
10. Maeda H, Fukita K, Oritani S, Ishida K, Zhu BL (1997) Evaluation of post-mortem oxymetry with reference to the causes of death. Forensic Sci Int 87(3):201-210
11. Oritani S, Nagai K, Zhu BL, Maeda H (1996) Estimation of carboxyhemoglobin concentrations in thermo-coagulated blood on a CO-oximeter system: an experimental study. Forensic Sci Int 83(3):211-218
12. Tominaga M, Michiue T, Ishikawa T, Kawamoto O, Oritani S, Ikeda K, Ogawa M, Maeda H (2013) Postmortem analyses of drugs in pericardial fluid and bone marrow aspirate. J Anal Toxicol 37(7):423-429
13. Wang Q, Ishikawa T, Michiue T, Zhu BL, Guan DW, Maeda H (2012) Stability of endogenous reference genes in postmortem human brains for normalization of quantitative real-time PCR data: comprehensive evaluation using geNorm, NormFinder, and BestKeeper. Int J Legal Med 126(6):943-952
14. Zhao S, Fernald RD (2005) Comprehensive algorithm for quantitative real-time polymerase chain reaction. J Comput Biol 12(8):1047-1064
15. Hellemans J, Mortier G, De Paepe A, Speleman F, Vandesompele J (2007) qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data. Genome Biol 8(2):R19
16. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25(4):402-408
17. Huth A, Vennemann B, Fracasso T, Lutz-Bonengel S, Vennemann M (2013) Apparent versus true gene expression changes of three hypoxia-related genes in autopsy derived tissue and the importance of normalisation. Int J Legal Med 127(2):335-344
18. Wang Q, Ishikawa T, Michiue T, Zhu BL, Guan DW, Maeda H (2012) Quantitative immunohistochemical analysis of human brain basic fibroblast growth factor, glial fibrillary acidic protein and single-stranded DNA expressions following traumatic brain injury. Forensic Sci Int 221(1-3):142-151
19. Wang Q, Ishikawa T, Michiue T, Zhu BL, Guan DW, Maeda H (2012) Evaluation of human brain damage in fatalities due to extreme environmental temperature by quantification of basic fibroblast growth factor (bFGF), glial fibrillary acidic protein (GFAP), S100beta and single-stranded DNA (ssDNA) immunoreactivities. Forensic Sci Int 219(1-3):259-264
20. Hollander M, Wolfe DA (1999) Nonparametric statistical methods. Wiley series in probability and statistics Texts and references section, 2nd edn. Wiley, New York
21. Gibbons JD, Chakraborti S (2011) Nonparametric statistical inference. Statistics, textbooks & monographs, 5th edn. Taylor & Francis, Boca Raton
22. Madea B, Saukko P, Oliva A, Musshoff F (2010) Molecular pathology in forensic medicine-introduction. Forensic Sci Int 203(1-3):3-14
23. Maeda H, Ishikawa T, Michiue T (2011) Forensic biochemistry for functional investigation of death: concept and practical application. Leg Med (Tokyo) 13(2):55-67
24. Koppelkamm A, Vennemann B, Fracasso T, Lutz-Bonengel S, Schmidt U, Heinrich M (2010) Validation of adequate endogenous reference genes for the normalisation of qPCR gene expression data in human post mortem tissue. Int J Legal Med 124(5):371-380
25. Kimura A, Ishida Y, Hayashi T, Nosaka M, Kondo T (2011) Estimating time of death based on the biological clock. Int J Legal Med 125(3):385-391
26. Koppelkamm A, Vennemann B, Lutz-Bonengel S, Fracasso T, Vennemann M (2011) RNA integrity in post-mortem samples: influencing parameters and implications on RT-qPCR assays. Int J Legal Med 125(4):573-580
27. Chen JH, Michiue T, Ishikawa T, Maeda H (2012) Molecular pathology of natriuretic peptides in the myocardium with special regard to fatal intoxication, hypothermia, and hyperthermia. Int J Legal Med 126(5):747-756
28. Zhang H, Adwanikar H, Werb Z, Noble-Haeusslein LJ (2010) Matrix metalloproteinases and neurotrauma: evolving roles in injury and reparative processes. Neuroscientist 16(2):156-170
29. Liu Y, Brown S, Shaikh J, Fishback JA, Matsumoto RR (2008) Relationship between methamphetamine exposure and matrix metalloproteinase 9 expression. Neuroreport 19(14):1407-1409
30. Urrutia A, Rubio-Araiz A, Gutierrez-Lopez MD, ElAli A, Hermann DM, O'Shea E, Colado MI (2013) A study on the effect of JNK inhibitor, SP600125, on the disruption of blood-brain barrier induced by methamphetamine. Neurobiol Dis 50:49-58
31. Rosenberg GA, Estrada EY, Dencoff JE (1998) Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain. Stroke 29(10):2189-2195
32. Svedin P, Hagberg H, Savman K, Zhu C, Mallard C (2007) Matrix metalloproteinase-9 gene knock-out protects the immature brain after cerebral hypoxia-ischemia. J Neurosci 27(7):1511-1518
33. Ramirez SH, Potula R, Fan S, Eidem T, Papugani A, Reichenbach N, Dykstra H, Weksler BB, Romero IA, Couraud PO, Persidsky Y (2009) Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells. J Cereb Blood Flow Metab 29(12):1933-1945
34. Tourdias T, Mori N, Dragonu I, Cassagno N, Boiziau C, Aussudre J, Brochet B, Moonen C, Petry KG, Dousset V (2011) Differential aquaporin 4 expression during edema build-up and resolution phases of brain inflammation. J Neuroinflammation 8:143
35. Fukuda AM, Pop V, Spagnoli D, Ashwal S, Obenaus A, Badaut J (2012) Delayed increase of astrocytic aquaporin 4 after juvenile traumatic brain injury: possible role in edema resolution? Neuroscience 222:366-378
36. Eugenin EA, Greco JM, Frases S, Nosanchuk JD, Martinez LR (2013) Methamphetamine alters blood brain barrier protein expression in mice, facilitating central nervous system infection by neurotropic Cryptococcus neoformans. J Infect Dis 208(4):699-704
37. Kast RE (2009) Use of FDA approved methamphetamine to allow adjunctive use of methylnaltrexone to mediate core anti-growth factor signaling effects in glioblastoma. J Neurooncol 94(2):163-167
38. Zhao D, Zhu BL, Ishikawa T, Quan L, Li DR, Maeda H (2006) Real-time RT-PCR quantitative assays and postmortem degradation profiles of erythropoietin, vascular endothelial growth factor and hypoxia-inducible factor 1 alpha mRNA transcripts in forensic autopsy materials. Leg Med (Tokyo) 8(2):132-136
39. Miyazato T, Ishikawa T, Michiue T, Maeda H (2012) Molecular pathology of pulmonary surfactants and cytokines in drowning compared with other asphyxiation and fatal hypothermia. Int J Legal Med 126(4):581-587