Quantitative immunohistochemical analysis of human brain basic fibroblast growth factor, glial fibrillary acidic protein and single-stranded DNA expressions following traumatic brain injury

Forensic Science International

Volumn 221, Issue 1-3, 2012, Pages 142-151

  Wang, Qi ^a,b   Ishikawa, Takaki ^a,b   Michiue, Tomomi ^a,b   Zhu, Bao Li ^c   Guan, Da Wei ^c   Maeda, Hitoshi ^a,b  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Medico legal Consultation and Postmortem Investigation Support Center MLCPI SC   (Japan)

^c CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Basic fibroblast growth factor; Glial fibrillary acidic protein; Human traumatic brain injury; Immunohistochemistry; Single stranded DNA

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; GLIAL FIBRILLARY ACIDIC PROTEIN; SINGLE STRANDED DNA;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOPSY; BRAIN HEMORRHAGE; BRAIN HERNIA; BRAIN WEIGHT; CHILD; DEATH; DECOMPRESSIVE CRANIECTOMY; FEMALE; FORENSIC PATHOLOGY; GENE EXPRESSION; GLIA; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; NERVE CELL DEGENERATION; PARIETAL LOBE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHOOL CHILD; SURVIVAL TIME; TRAUMATIC BRAIN INJURY; WHITE MATTER;

EID: 84864349184     PISSN: 03790738     EISSN: 18726283     Source Type: Journal    
DOI: 10.1016/j.forsciint.2012.04.025     Document Type: Article

References (42)

1. Greenfield's Neuropathology 2002, Arnold, London. 7th ed. D.I. Graham, P.L. Lantos (Eds.).
2. Saukko P., Knight B. Knight's Forensic Pathology 2004, Arnold, London. 3rd ed.
3. Oehmichen M., Auer R.N., König H.G. Forensic Neuropathology and Associated Neurology 2006, Springer-Verlag, Berlin/Heidelberg/New York.
4. Bratzke H. Research in forensic neurotraumatology. Forensic Sci. Int. 2004, 144:157-165.
5. Dressler J., Hanisch U., Kuhlisch E., Geiger K.D. Neuronal and glial apoptosis in human traumatic brain injury. Int. J. Legal Med. 2007, 121:365-375.
6. Takamiya M., Fujita S., Saigusa K., Aoki Y. Simultaneous detections of 27 cytokines during cerebral wound healing by multiplexed bead-based immunoassay for wound age estimation. J. Neurotrauma 2007, 24:1833-1844.
7. Hausmann R., Riess R., Fieguth A., Betz P. Immunohistochemical investigations on the course of astroglial GFAP expression following human brain injury. Int. J. Legal Med. 2000, 113:70-75.
8. Hausmann R., Betz P. Course of glial immunoreactivity for vimentin, tenascin and alpha1-antichymotrypsin after traumatic injury to human brain. Int. J. Legal Med. 2001, 114:338-342.
9. Hausmann R., Kaiser A., Lang C., Bohnert M., Betz P. A quantitative immunohistochemical study on the time-dependent course of acute inflammatory cellular response to human brain injury. Int. J. Legal Med. 1999, 112:227-232.
10. Walter T., Meissner C., Oehmichen M. Pathomorphological staging of subdural hemorrhages: statistical analysis of posttraumatic histomorphological alterations. Leg. Med. (Tokyo) 2009, 11(Suppl. 1):S56-S62.
11. Oehmichen M., Walter T., Meissner C., Friedrich H.J. Time course of cortical hemorrhages after closed traumatic brain injury: statistical analysis of posttraumatic histomorphological alterations. J. Neurotrauma 2003, 20:87-103.
12. Sahuquillo J., Arikan F. Decompressive craniectomy for the treatment of refractory high intracranial pressure in traumatic brain injury. Cochrane Database Syst. Rev. 2006, CD003983.
13. Byard R.W., Bhatia K.D., Reilly P.L., Vink R. How rapidly does cerebral swelling follow trauma? Observations using an animal model and possible implications in infancy. Leg. Med. (Tokyo) 2009, 11(Suppl. 1):S128-S131.
14. O'Connor C.A., Cernak I., Vink R. The temporal profile of edema formation differs between male and female rats following diffuse traumatic brain injury. Acta Neurochir. Suppl. 2006, 96:121-124.
15. Liedtke W., Edelmann W., Bieri P.L., Chiu F.C., Cowan N.J., Kucherlapati R., Raine C.S. GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination. Neuron 1996, 17:607-615.
16. Wang Q., Ishikawa T., Michiue T., Zhu B.L., Maeda H. Evaluation of human brain damage in fire fatality by quantification of basic fibroblast growth factor (bFGF), glial fibrillary acidic protein (GFAP) and single-stranded DNA (ssDNA) immunoreactivities. Forensic Sci. Int. 2011, 211:19-26.
17. Wang Q., Ishikawa T., Michiue T., Zhu B.L., Guan D.W., Maeda H. Evaluation of human brain damage in fatalities due to extreme environmental temperature by quantification of basic fibroblast growth factor (bFGF), glial fibrillary acidic protein (GFAP), S100beta and single-stranded DNA (ssDNA) immunoreactivities. Forensic Sci. Int. 2012, 10.1016/j.forsciint.2012.01.015.
18. Bikfalvi A., Klein S., Pintucci G., Rifkin D.B. Biological roles of fibroblast growth factor-2. Endocr. Rev. 1997, 18:26-45.
19. Alzheimer C., Werner S. Fibroblast growth factors and neuroprotection. Adv. Exp. Med. Biol. 2002, 513:335-351.
20. Chen J., Jin K., Chen M., Pei W., Kawaguchi K., Greenberg D.A., Simon R.P. Early detection of DNA strand breaks in the brain after transient focal ischemia: implications for the role of DNA damage in apoptosis and neuronal cell death. J. Neurochem. 1997, 69:232-245.
21. Michiue T., Ishikawa T., Quan L., Li D.R., Zhao D., Komatsu A., Zhu B.L., Maeda H. Single-stranded DNA as an immunohistochemical marker of neuronal damage in human brain: an analysis of autopsy material with regard to the cause of death. Forensic Sci. Int. 2008, 178:185-191.
22. Graham D.I., Lawrence A.E., Adams J.H., Doyle D., McLellan D.R. Brain damage in fatal non-missile head injury without high intracranial pressure. J. Clin. Pathol. 1988, 41:34-37.
23. Louis J.C., Magal E., Gerdes W., Seifert W. Survival-promoting and protein kinase C-regulating roles of basic FGF for hippocampal neurons exposed to phorbol ester, glutamate and ischaemia-like conditions. Eur. J. Neurosci. 1993, 5:1610-1621.
24. Dietrich W.D., Alonso O., Busto R., Finklestein S.P. Posttreatment with intravenous basic fibroblast growth factor reduces histopathological damage following fluid-percussion brain injury in rats. J. Neurotrauma 1996, 13:309-316.
25. Deguchi Y., Okutsu H., Okura T., Yamada S., Kimura R., Yuge T., Furukawa A., Morimoto K., Tachikawa M., Ohtsuki S., Hosoya K., Terasaki T. Internalization of basic fibroblast growth factor at the mouse blood-brain barrier involves perlecan, a heparan sulfate proteoglycan. J. Neurochem. 2002, 83:381-389.
26. Macmillan C.S., Grant I.S., Andrews P.J. Pulmonary and cardiac sequelae of subarachnoid haemorrhage: time for active management?. Intensive Care Med. 2002, 28:1012-1023.
27. Parizel P.M., Makkat S., Jorens P.G., Ozsarlak O., Cras P., Van Goethem J.W., van den Hauwe L., Verlooy J., De Schepper A.M. Brainstem hemorrhage in descending transtentorial herniation (Duret hemorrhage). Intensive Care Med. 2002, 28:85-88.
28. Graham D.I., Lawrence A.E., Adams J.H., Doyle D., McLellan D.R. Brain damage in non-missile head injury secondary to high intracranial pressure. Neuropathol. Appl. Neurobiol. 1987, 13:209-217.
29. Tamatani M., Ogawa S., Nunez G., Tohyama M. Growth factors prevent changes in Bcl-2 and Bax expression and neuronal apoptosis induced by nitric oxide. Cell Death Differ. 1998, 5:911-919.
30. Ay I., Sugimori H., Finklestein S.P. Intravenous basic fibroblast growth factor (bFGF) decreases DNA fragmentation and prevents downregulation of Bcl-2 expression in the ischemic brain following middle cerebral artery occlusion in rats. Brain Res. Mol. Brain Res. 2001, 87:71-80.
31. Stoica B.A., Faden A.I. Cell death mechanisms and modulation in traumatic brain injury. Neurotherapeutics 2010, 7:3-12.
32. Castejon O.J., Arismendi G.J. Nerve cell death types in the edematous human cerebral cortex. J. Submicrosc. Cytol. Pathol. 2006, 38:21-36.
33. Klatzo I. Evolution of brain edema concepts. Acta Neurochir. Suppl. (Wien) 1994, 60:3-6.
34. Unterberg A.W., Stover J., Kress B., Kiening K.L. Edema and brain trauma. Neuroscience 2004, 129:1021-1029.
35. Barzo P., Marmarou A., Fatouros P., Hayasaki K., Corwin F. Contribution of vasogenic and cellular edema to traumatic brain swelling measured by diffusion-weighted imaging. J. Neurosurg. 1997, 87:900-907.
36. Hellal F., Bonnefont-Rousselot D., Croci N., Palmier B., Plotkine M., Marchand-Verrecchia C. Pattern of cerebral edema and hemorrhage in a mice model of diffuse brain injury. Neurosci. Lett. 2004, 357:21-24.
37. Marmarou A., Fatouros P.P., Barzo P., Portella G., Yoshihara M., Tsuji O., Yamamoto T., Laine F., Signoretti S., Ward J.D., Bullock M.R., Young H.F. Contribution of edema and cerebral blood volume to traumatic brain swelling in head-injured patients. J. Neurosurg. 2000, 93:183-193.
38. Kimelberg H.K. Current concepts of brain edema. Review of laboratory investigations. J. Neurosurg. 1995, 83:1051-1059.
39. Matute C., Domercq M., Sanchez-Gomez M.V. Glutamate-mediated glial injury: mechanisms and clinical importance. Glia 2006, 53:212-224.
40. Barbeito L.H., Pehar M., Cassina P., Vargas M.R., Peluffo H., Viera L., Estevez A.G., Beckman J.S. A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis. Brain Res. Brain Res. Rev. 2004, 47:263-274.
41. Zador Z., Bloch O., Yao X., Manley G.T. Aquaporins: role in cerebral edema and brain water balance. Prog. Brain Res. 2007, 161:185-194.
42. Maleszewski J., Lu J., Fox-Talbot K., Halushka M.K. Robust immunohistochemical staining of several classes of proteins in tissues subjected to autolysis. J. Histochem. Cytochem. 2007, 55:597-606.