Sirt1 deletion leads to enhanced inflammation and aggravates endotoxin-induced acute kidney injury

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Gao, Rong ^a,b   Chen, Jiao ^b   Hu, Yuxin ^a,b   Li, Zhenyu ^b   Wang, Shuxia ^b   Shetty, Sreerama ^c   Fu, Jian ^b  

^a JILIN UNIVERSITY   (China)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SIRTUIN 1; STAT3 PROTEIN; VASCULAR CELL ADHESION MOLECULE 1; LIPOPOLYSACCHARIDE;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DISEASE EXACERBATION; DISEASE SEVERITY; DOWN REGULATION; ENDOTOXEMIA; ENZYME ACTIVATION; INFLAMMATION; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL; CHEMICALLY INDUCED; DISEASE COURSE; DISEASE MODEL; GENE DELETION; GENE EXPRESSION; GENETICS; KIDNEY TUBULE; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

ACUTE KIDNEY INJURY; ANIMALS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENDOTOXINS; GENE DELETION; GENE EXPRESSION; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; KIDNEY TUBULES; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, KNOCKOUT; NEUTROPHIL INFILTRATION; SIGNAL TRANSDUCTION; SIRTUIN 1; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84902523833     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0098909     Document Type: Article

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