Eckol protects V79-4 lung fibroblast cells against γ-ray radiation-induced apoptosis via the scavenging of reactive oxygen species and inhibiting of the c-Jun NH2-terminal kinase pathway

European Journal of Pharmacology

Volumn 591, Issue 1-3, 2008, Pages 114-123

  Zhang, Rui ^a   Kang, Kyoung Ah ^a   Piao, Mei Jing ^a   Ko, Dong Ok ^a   Wang, Zhi Hong ^a   Lee, In Kyung ^b   Kim, Bum Joon ^b   Jeong, Il Yun ^c   Shin, Taekyun ^d   Park, Jae Woo ^d   Lee, Nam Ho ^d   Hyun, Jin Won ^a  

^a Applied Radiological Science Research Institute   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c Korea Atomic Energy Research Institute   (South Korea)

^d Jeju National University   (South Korea)

Author keywords

Apoptosis; Eckol; JNK pathway; Oxidative stress; Radiation; Reactive oxygen species

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; DNA; ECKOL; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PHLOROGLUCINOL DERIVATIVE; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TANNIN DERIVATIVE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATTENUATION; BROWN ALGA; CELL PROTECTION; CELL VIABILITY; CHO CELL; CONTROLLED STUDY; DNA DAMAGE; ECKLONIA CAVA; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; GAMMA RADIATION; INTRACELLULAR TRANSPORT; LIPID PEROXIDATION; LUNG FIBROBLAST; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION INJURY; RADIATION PROTECTION;

ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; CRICETINAE; CRICETULUS; DIOXINS; DNA DAMAGE; FIBROBLASTS; FREE RADICAL SCAVENGERS; GAMMA RAYS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LUNG; MAP KINASE KINASE 4; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TRANSCRIPTION FACTOR AP-1;

EID: 48749131954     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.06.086     Document Type: Article

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