The use of induced pluripotent stem cells to reveal pathogenic gene mutations and explore treatments for retinitis pigmentosa

Molecular Brain

Volumn 7, Issue 1, 2014, Pages

  Yoshida, Tetsu ^a,b   Ozawa, Yoko ^a,b   Suzuki, Keiichiro ^c   Yuki, Kenya ^a,b   Ohyama, Manabu ^a   Akamatsu, Wado ^b   Matsuzaki, Yumi ^b   Shimmura, Shigeto ^a   Mitani, Kohnosuke ^c   Tsubota, Kazuo ^a   Okano, Hideyuki ^b  

^a KEIO UNIVERSITY   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Drug screening; ER stress; Gene delivery; iPS cells; Neurodegeneration; Retina

Indexed keywords

2 (4 AMINO 1 ISOPROPYL 1H PYRAZOLO[3,4 D]PYRIMIDIN 3 YL) 1H INDOL 5 OL; 5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; AMINO ACID; ENHANCED GREEN FLUORESCENT PROTEIN; GLUTAMIC ACID; RAPAMYCIN; RECOVERIN; RHODOPSIN; SALUBRINAL;

ADULT; ALLELE; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG SCREENING; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; FEMALE; FLOW CYTOMETRY; GENE MUTATION; GENE TARGETING; GENE TRANSFER; GENOME; GERM LAYER; HELPER DEPENDENT ADENOVIRUS; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; MUTAGENESIS; PHOTORECEPTOR CELL; PLURIPOTENT STEM CELL; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; RETINA CELL; RETINITIS PIGMENTOSA; TERATOMA;

APOPTOSIS; AUTOPHAGY; BASE SEQUENCE; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL LINE; DRUG EVALUATION, PRECLINICAL; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE TARGETING; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION; RETINAL ROD PHOTORECEPTOR CELLS; RETINITIS PIGMENTOSA; RHODOPSIN;

EID: 84902476568     PISSN: None     EISSN: 17566606     Source Type: Journal    
DOI: 10.1186/1756-6606-7-45     Document Type: Article

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