Cord blood CD4+CD25+ regulatory T cells fail to inhibit cord blood NK cell functions due to insufficient production and expression of TGF-beta1

Cellular Immunology

Volumn 290, Issue 1, 2014, Pages 89-95

  Xu, Liqing ^a,b,c   Tanaka, Shigeki ^a,b   Bonno, Motoki ^a,b   Ido, Masaru ^a,b   Kawai, Masatoshi ^d   Yamamoto, Hatsumi ^a,b   Komada, Yoshihiro ^b  

^a National Hospital Organization Mie Chuo Medical Center   (Japan)

^b MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c SHANGHAI CHILDREN S MEDICAL CENTER   (China)

^d MUKOGAWA WOMEN'S UNIVERSITY   (Japan)

Author keywords

NK cells; TGF beta1; Umbilical cord blood

Indexed keywords

CD69 ANTIGEN; RECOMBINANT HUMAN INTERLEUKIN 2; RECOMBINANT PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ADULT; ANTIGEN EXPRESSION; ARTICLE; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTOXICITY; CYTOTOXICITY ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LYMPHOCYTE FUNCTION; MIXED LYMPHOCYTE CULTURE; NATURAL KILLER CELL; NEWBORN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; T CELL DEPLETION; UMBILICAL CORD BLOOD;

CD4(+)CD25(+) T REGULATORY CELLS; NK CELLS; TGF-BETA1; UMBILICAL CORD BLOOD;

ADULT; ANTIGENS, CD; ANTIGENS, CD4; ANTIGENS, CD56; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOKINES; FETAL BLOOD; HUMANS; INFANT, NEWBORN; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; KILLER CELLS, NATURAL; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA1; YOUNG ADULT;

EID: 84902469777     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2014.05.007     Document Type: Article

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