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Volumn 66, Issue 6, 2012, Pages 429-434

The therapeutic potential of human umbilical cord blood transplantation for neonatal hypoxic-ischemic brain injury and ischemic stroke

Author keywords

Cell transplantation; Ischemic stroke; Neonatal hypoxic ischemic brain injury; Stem cells; Umbilical cord blood

Indexed keywords

ANIMAL; CEREBROVASCULAR ACCIDENT; CORD BLOOD STEM CELL TRANSPLANTATION; DISEASE MODEL; HUMAN; HYPOXIC ISCHEMIC ENCEPHALOPATHY; METHODOLOGY; NEWBORN; REVIEW;

EID: 84873723840     PISSN: 0386300X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (15)

References (50)
  • 3
    • 34748833133 scopus 로고    scopus 로고
    • The potential of cord blood stem cells for use in regenerative medicine
    • Harris DT, Badowski M, Ahmad N and Gaballa MA: The potential of cord blood stem cells for use in regenerative medicine. Expert Opin Biol Ther (2007) 7: 1311-1322.
    • (2007) Expert Opin Biol Ther , vol.7 , pp. 1311-1322
    • Harris, D.T.1    Badowski, M.2    Ahmad, N.3    Gaballa, M.A.4
  • 6
    • 3543003475 scopus 로고    scopus 로고
    • Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood
    • Bieback K, Kern S, Kluter H and Eichler H: Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood. Stem Cells (2004) 22: 625-634.
    • (2004) Stem Cells , vol.22 , pp. 625-634
    • Bieback, K.1    Kern, S.2    Kluter, H.3    Eichler, H.4
  • 7
    • 84862838061 scopus 로고    scopus 로고
    • New approach to isolate mesenchymal stem cell (MSC) from human umbilical cord blood
    • Hussain I, Magd SA, Eremin O and El-Sheemy M: New approach to isolate mesenchymal stem cell (MSC) from human umbilical cord blood. Cell Biol Int (2012) 36: 595-600.
    • (2012) Cell Biol Int , vol.36 , pp. 595-600
    • Hussain, I.1    Magd, S.A.2    Eremin, O.3    El-Sheemy, M.4
  • 9
    • 84862195758 scopus 로고    scopus 로고
    • Human umbilical cord blood-derived stromal cells are superior to human umbilical cord blood-derived mesenchymal stem cells in inducing myeloid lineage differentiation in vitro
    • Sun HP, Zhang X, Chen XH, Zhang C, Gao L, Feng YM, Peng XG and Gao L: Human umbilical cord blood-derived stromal cells are superior to human umbilical cord blood-derived mesenchymal stem cells in inducing myeloid lineage differentiation in vitro. Stem Cells Dev (2012) 21: 1429-1440.
    • (2012) Stem Cells Dev , vol.21 , pp. 1429-1440
    • Sun, H.P.1    Zhang, X.2    Chen, X.H.3    Zhang, C.4    Gao, L.5    Feng, Y.M.6    Peng, X.G.7    Gao, L.8
  • 10
    • 0035199276 scopus 로고    scopus 로고
    • Multilineage differentiation activity by cells isolated from umbilical cord blood: expression of bone, fat, and neural markers
    • Goodwin HS, Bicknese AR, Chien SN, Bogucki BD, Quinn CO and Wall DA: Multilineage differentiation activity by cells isolated from umbilical cord blood: expression of bone, fat, and neural markers. Biol Blood Marrow Transplant (2001) 7: 581-588.
    • (2001) Biol Blood Marrow Transplant , vol.7 , pp. 581-588
    • Goodwin, H.S.1    Bicknese, A.R.2    Chien, S.N.3    Bogucki, B.D.4    Quinn, C.O.5    Wall, D.A.6
  • 13
    • 79251563456 scopus 로고    scopus 로고
    • Perinatal hypoxic-ischemic encephalopathy
    • Epub2011Dec13
    • Lai MC, YangSN: Perinatal hypoxic-ischemic encephalopathy. J Biomed Biotechnol (2011) Epub2011Dec13.
    • (2011) J Biomed Biotechnol
    • Lai, M.C.1    Yang, S.N.2
  • 14
    • 0002445427 scopus 로고
    • Anoxic-ischemic encephalopathy in rats
    • LEVINE S: Anoxic-ischemic encephalopathy in rats. Am J Pathol (1960)36: 1-17.
    • (1960) Am J Pathol , vol.36 , pp. 1-17
    • Levine, S.1
  • 15
    • 0019366919 scopus 로고
    • The influence of mmaturity on hypoxic-ischemic brain damage in the rat
    • Rice JE 3rd, Vannucci RC and Brierley JB: The influence of mmaturity on hypoxic-ischemic brain damage in the rat. Ann Neural (1981)9: 131-141.
    • (1981) Ann Neural , vol.9 , pp. 131-141
    • Rice, J.E.1    Vannucci, R.C.2    Brierley, J.B.3
  • 17
    • 77949617579 scopus 로고    scopus 로고
    • Human cord blood transplan-tation in a neonatal rat model of hypoxic-ischemic brain damage functional outcome related to neuroprotection in the striatum
    • Pimentel-Coelho PM, Magalhaes ES, Lopes LM, deAzevedo LC Santiago MF and Mendez-Otero R: Human cord blood transplan-tation in a neonatal rat model of hypoxic-ischemic brain damage functional outcome related to neuroprotection in the striatum Stem Cells Dev (2010) 19: 351-358.
    • (2010) Stem Cells Dev , vol.19 , pp. 351-358
    • Pimentel-Coelho, P.M.1    Magalhaes, E.S.2    Lopes, L.M.3    deAzevedo, L.C.4    Santiago, M.F.5    Mendez-Otero, R.6
  • 19
    • 79957818809 scopus 로고    scopus 로고
    • Human umbilical cord blood cells restore brain damage induced changes in rat somatosensory cortex
    • Geissler M, Dinse HR, Neuhoff S, Kreikemeier K and Meier C Human umbilical cord blood cells restore brain damage induced changes in rat somatosensory cortex. PLoS One (2011) 6: e20194.
    • (2011) PLoS One , vol.6
    • Geissler, M.1    Dinse, H.R.2    Neuhoff, S.3    Kreikemeier, K.4    Meier, C.5
  • 20
    • 67049155611 scopus 로고    scopus 로고
    • Hemispheric brain injury and behavioral deficits induced by severe neonatal hypoxia-ischemia in rats are not attenuated by intravenous admin-istration of human umbilical cord blood cells
    • de Paula S, Vitola AS, Greggio S, de Paula D, Mello PB Lubianca JM, Xavier LL, Fiori HH and Dacosta JC: Hemispheric brain injury and behavioral deficits induced by severe neonatal hypoxia-ischemia in rats are not attenuated by intravenous admin-istration of human umbilical cord blood cells. Pediatr Res (2009) 65: 631-635.
    • (2009) Pediatr Res , vol.65 , pp. 631-635
    • de Paula, S.1    Vitola, A.S.2    Greggio, S.3    de Paula, D.4    Mello, P.B.5    Lubianca, J.M.6    Xavier, L.L.7    Fiori, H.H.8    Dacosta, J.C.9
  • 21
    • 0035167706 scopus 로고    scopus 로고
    • Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats
    • Chen J, Sanberg PR, Li Y, Wang L, Lu M, Willing AE, Sanchez-Ramos J and Chopp M: Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats. Stroke (2001) 32: 2682-2688.
    • (2001) Stroke , vol.32 , pp. 2682-2688
    • Chen, J.1    Sanberg, P.R.2    Li, Y.3    Wang, L.4    Lu, M.5    Willing, A.E.6    Sanchez-Ramos, J.7    Chopp, M.8
  • 22
    • 4744341332 scopus 로고    scopus 로고
    • Infusion of human umbilical cord blood cells in a rat model of stroke dose-dependently rescues behavioral deficits and reduces infarct volume
    • Vendrame M, Cassady J, NewcombJ, Butler T, Pennypacker KR Zigova T, Sanberg CD, Sanberg PR and Willing AE: Infusion of human umbilical cord blood cells in a rat model of stroke dose-dependently rescues behavioral deficits and reduces infarct volume. Stroke (2004) 35: 2390-2395.
    • (2004) Stroke , vol.35 , pp. 2390-2395
    • Vendrame, M.1    Cassady, J.2    Newcomb, J.3    Butler, T.4    Pennypacker, K.R.5    Zigova, T.6    Sanberg, C.D.7    Sanberg, P.R.8    Willing, A.E.9
  • 25
    • 4744358048 scopus 로고    scopus 로고
    • Central Nervous System Entry of Peripherally Injected Umbilical Cord Blood Cells Is Not Required for Neuroprotection
    • Borlongan CV, Hadman M, Sanberg CD and Sanberg PR: Central Nervous System Entry of Peripherally Injected Umbilical Cord Blood Cells Is Not Required for Neuroprotection. Stroke (2004) 35: 2385-2389.
    • (2004) Stroke , vol.35 , pp. 2385-2389
    • Borlongan, C.V.1    Hadman, M.2    Sanberg, C.D.3    Sanberg, P.R.4
  • 26
    • 84863012210 scopus 로고    scopus 로고
    • Therapeutic effects of human umbilical cord blood-derived mesenchymal stem cells after intrathecal administration by lumbar puncture in a rat model of cerebral isch-emia
    • Lim JY, Jeong CH, Jun JA, Kim SM, Ryu CH, Hou Y, Oh W. Chang JW and Jeun SS: Therapeutic effects of human umbilical cord blood-derived mesenchymal stem cells after intrathecal administration by lumbar puncture in a rat model of cerebral isch-emia. Stem Cell Res Ther (2011) 2: 38.
    • (2011) Stem Cell Res Ther , vol.2 , pp. 38
    • Lim, J.Y.1    Jeong, C.H.2    Jun, J.A.3    Kim, S.M.4    Ryu, C.H.5    Hou, Y.6    Oh, W.7    Chang, J.W.8    Jeun, S.S.9
  • 28
    • 34250307233 scopus 로고    scopus 로고
    • Proliferation, differentiation, and cytokine secretion of human umbilical cord blood-derived mononuclear cells in vitro
    • Neuhoff S, Moers J, Rieks M, Grunwald T, Jensen A, Dermietzel R and Meier C: Proliferation, differentiation, and cytokine secretion of human umbilical cord blood-derived mononuclear cells in vitro. Exp Hematol (2007) 35: 1119-1131.
    • (2007) Exp Hematol , vol.35 , pp. 1119-1131
    • Neuhoff, S.1    Moers, J.2    Rieks, M.3    Grunwald, T.4    Jensen, A.5    Dermietzel, R.6    Meier, C.7
  • 30
    • 33745198969 scopus 로고    scopus 로고
    • Cytokines produced by cultured human umbilical cord blood (HUCB) cells: implications for brain repair
    • Newman MB, Willing AE, Manresa JJ, Sanberg CD and Sanberg PR: Cytokines produced by cultured human umbilical cord blood (HUCB) cells: implications for brain repair. Exp Neural (2006) 199: 201-208.
    • (2006) Exp Neural , vol.199 , pp. 201-208
    • Newman, M.B.1    Willing, A.E.2    Manresa, J.J.3    Sanberg, C.D.4    Sanberg, P.R.5
  • 31
    • 0034255042 scopus 로고    scopus 로고
    • BDNF protects the neonatal brain from hypoxic-ischamic injury in vivo via the ERK pathway
    • Han BH and Holtzman DM: BDNF protects the neonatal brain from hypoxic-ischamic injury in vivo via the ERK pathway. J Neurosci (2000) 20: 5775-5781.
    • (2000) J Neurosci , vol.20 , pp. 5775-5781
    • Han, B.H.1    Holtzman, D.M.2
  • 32
    • 79960109924 scopus 로고    scopus 로고
    • Therapeutic time window for the neuroprotective effects of NGF when administered after focal cerebral ischemia
    • Yang JP, Liu HJ, Yang H and Feng PY: Therapeutic time window for the neuroprotective effects of NGF when administered after focal cerebral ischemia. Neural Sci (2011) 32: 433-441.
    • (2011) Neural Sci , vol.32 , pp. 433-441
    • Yang, J.P.1    Liu, H.J.2    Yang, H.3    Feng, P.Y.4
  • 33
    • 84856726620 scopus 로고    scopus 로고
    • Human umbilical cord blood cells protect oligo-dendrocytes from brain ischemia through Akt signal transduction
    • Rowe DD, Leonardo CC, Recio JA, Collier LA, Willing AE and Pennypacker KR: Human umbilical cord blood cells protect oligo-dendrocytes from brain ischemia through Akt signal transduction. J Biol Chem (2012) 287: 4177-4187.
    • (2012) J Biol Chem , vol.287 , pp. 4177-4187
    • Rowe, D.D.1    Leonardo, C.C.2    Recio, J.A.3    Collier, L.A.4    Willing, A.E.5    Pennypacker, K.R.6
  • 34
    • 66749173431 scopus 로고    scopus 로고
    • Mechanisms and targets for angiogenic therapy after stroke
    • Navaratna D, Guo S, Arai K and Lo EH: Mechanisms and targets for angiogenic therapy after stroke. Cell Adh Migr (2009) 3: 216-223.
    • (2009) Cell Adh Migr , vol.3 , pp. 216-223
    • Navaratna, D.1    Guo, S.2    Arai, K.3    Lo, E.H.4
  • 37
    • 0035874498 scopus 로고    scopus 로고
    • Numerous growth factors, cytokines, and chemok-ines are secreted by human CD34(+) cells, myeloblasts, erythro-blasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner
    • Majka M, Janowska-Wieczorek A, Ratajczak J, Ehrenman K. Pietrzkowski Z, Kowalska MA, Gewirtz AM, Emerson SG and Ratajczak MZ: Numerous growth factors, cytokines, and chemok-ines are secreted by human CD34(+) cells, myeloblasts, erythro-blasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner. Blood (2001) 97: 3075-3085.
    • (2001) Blood , vol.97 , pp. 3075-3085
    • Majka, M.1    Janowska-Wieczorek, A.2    Ratajczak, J.3    Ehrenman, K.4    Pietrzkowski, Z.5    Kowalska, M.A.6    Gewirtz, A.M.7    Emerson, S.G.8    Ratajczak, M.Z.9
  • 38
    • 34548324336 scopus 로고    scopus 로고
    • Enhancement of neuroplasticity through upregu-lation of betal-integrin in human umbilical cord-derived stromal cell implanted stroke model
    • Ding DC, Shyu WC, Chiang MF, Lin SZ, Chang YC, Wang HJ Su CY and Li H: Enhancement of neuroplasticity through upregu-lation of betal-integrin in human umbilical cord-derived stromal cell implanted stroke model. Neurobiol Dis (2007) 27: 339-353.
    • (2007) Neurobiol Dis , vol.27 , pp. 339-353
    • Ding, D.C.1    Shyu, W.C.2    Chiang, M.F.3    Lin, S.Z.4    Chang, Y.C.5    Wang, H.J.6    Su, C.Y.7    Li, H.8
  • 40
    • 84866317789 scopus 로고    scopus 로고
    • Transplantation of human umbilical cord blood cells mediated beneficial effects on apoptosis, angiogenesis and neuronal survival after hypoxic-ischemic brain injury in rats
    • Rosenkranz K, Kumbruch S, Tenbusch M, Marcus K, Marschner K. Dermietzel R and Meier C: Transplantation of human umbilical cord blood cells mediated beneficial effects on apoptosis, angiogenesis and neuronal survival after hypoxic-ischemic brain injury in rats. Cell Tissue Res (2012) 348: 429-438.
    • (2012) Cell Tissue Res , vol.348 , pp. 429-438
    • Rosenkranz, K.1    Kumbruch, S.2    Tenbusch, M.3    Marcus, K.4    Marschner, K.5    Dermietzel, R.6    Meier, C.7
  • 41
    • 34648839855 scopus 로고    scopus 로고
    • Angiopoietin1/Tie2 and VEGF/Flk1 induced by MSC treatment amplifies angiogenesis and vascular stabilization after stroke
    • Zacharek A, Chen J, Cui X, Li A, Li Y, Roberts C, Feng Y, Gao Q and Chopp M: Angiopoietin1/Tie2 and VEGF/Flk1 induced by MSC treatment amplifies angiogenesis and vascular stabilization after stroke. J Cereb Blood Flow Metab (2007) 27: 1684-1691.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 1684-1691
    • Zacharek, A.1    Chen, J.2    Cui, X.3    Li, A.4    Li, Y.5    Roberts, C.6    Feng, Y.7    Gao, Q.8    Chopp, M.9
  • 42
    • 71049180369 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: therapeutic approaches
    • Lakhan SE, Kirchgessner A and Hofer M: Inflammatory mechanisms in ischemic stroke: therapeutic approaches. J Transl Med (2009) 7: 97.
    • (2009) J Transl Med , vol.7 , pp. 97
    • Lakhan, S.E.1    Kirchgessner, A.2    Hofer, M.3
  • 45
    • 84871538038 scopus 로고    scopus 로고
    • Long-lasting paracrine effects of human cord blood cells (hUCBCs) on damaged neocortex in an animal model of cerebral palsy
    • Bae SH, KongTH, Lee HS, Kim KS, Hong KS, Chopp M, Kang MS and Moon J: Long-lasting paracrine effects of human cord blood cells (hUCBCs) on damaged neocortex in an animal model of cerebral palsy. Cell Transplant (2012).
    • (2012) Cell Transplant
    • Bae, S.H.1    Kong, T.H.2    Lee, H.S.3    Kim, K.S.4    Hong, K.S.5    Chopp, M.6    Kang, M.S.7    Moon, J.8
  • 46
    • 84860222551 scopus 로고    scopus 로고
    • Inflammation during fetal and neonatal life: implications for neurologic and neuropsychiatric disease in children and adults
    • Hagberg H, Gressens P and Mallard C: Inflammation during fetal and neonatal life: implications for neurologic and neuropsychiatric disease in children and adults. Ann Neural (2012) 71: 444-457.
    • (2012) Ann Neural , vol.71 , pp. 444-457
    • Hagberg, H.1    Gressens, P.2    Mallard, C.3
  • 47
    • 81755173570 scopus 로고    scopus 로고
    • Role of microglia in CNS inflammation
    • Graeber MB, Li W and Rodriguez ML: Role of microglia in CNS inflammation. FEBS Lett (2011) 585: 3798-3805.
    • (2011) FEBS Lett , vol.585 , pp. 3798-3805
    • Graeber, M.B.1    Li, W.2    Rodriguez, M.L.3
  • 48
    • 84864278895 scopus 로고    scopus 로고
    • Intestinal ischemia/reperfusion enhances microglial activation and induces cerebral injury and memory dysfunction in rats
    • Zhou J, Huang WQ, Li C, Wu GY, Li YS, Wen SH, Lei WL and Liu KX: Intestinal ischemia/reperfusion enhances microglial activation and induces cerebral injury and memory dysfunction in rats. Crit Care Med (2012) 40: 2438-2448.
    • (2012) Crit Care Med , vol.40 , pp. 2438-2448
    • Zhou, J.1    Huang, W.Q.2    Li, C.3    Wu, G.Y.4    Li, Y.S.5    Wen, S.H.6    Lei, W.L.7    Liu, K.X.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.