-
1
-
-
0022886091
-
Identification of the protein encoded by the human diffuse B-cell lymphoma (dbl) oncogene
-
Srivastava, S. K., Wheelock, R. H., Aaronson, S. A., and Eva, A. (1986) Identification of the protein encoded by the human diffuse B-cell lymphoma (dbl) oncogene. Proc. Natl. Acad. Sci. U.S.A. 83, 8868-8872 (Pubitemid 17223502)
-
(1986)
Proceedings of the National Academy of Sciences of the United States of America
, vol.83
, Issue.23
, pp. 8868-8872
-
-
Srivastava, S.K.1
Wheelock, R.H.P.2
Aaronson, S.A.3
Eva, A.4
-
2
-
-
0026044409
-
Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product
-
Hart, M. J., Eva, A., Evans, T., Aaronson, S. A., and Cerione, R. A. (1991) Catalysis of guanine nucleotide exchange on the Cdc42Hs protein by the dbl oncogene product. Nature 354, 311-314 (Pubitemid 21896884)
-
(1991)
Nature
, vol.354
, Issue.6351
, pp. 311-314
-
-
Hart, M.J.1
Eva, A.2
Evans, T.3
Aaronson, S.A.4
Cerione, R.A.5
-
3
-
-
0027276925
-
Pleckstrin domain homology
-
Haslam, R. J., Koide, H. B., and Hemmings, B. A. (1993) Pleckstrin domain homology. Nature 363, 309-310
-
(1993)
Nature
, vol.363
, pp. 309-310
-
-
Haslam, R.J.1
Koide, H.B.2
Hemmings, B.A.3
-
4
-
-
0035375109
-
Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain
-
Russo, C., Gao, Y., Mancini, P., Vanni, C., Porotto, M., Falasca, M., Torrisi, M. R., Zheng, Y., and Eva, A. (2001) Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain. J. Biol. Chem. 276, 19524-19531
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19524-19531
-
-
Russo, C.1
Gao, Y.2
Mancini, P.3
Vanni, C.4
Porotto, M.5
Falasca, M.6
Torrisi, M.R.7
Zheng, Y.8
Eva, A.9
-
5
-
-
0029783037
-
The pleckstrin homology domain mediates transformation by oncogenic Dbl through specific intracellular targeting
-
DOI 10.1074/jbc.271.32.19017
-
Zheng, Y., Zangrilli, D., Cerione, R. A., and Eva, A. (1996) The pleckstrin homology domain mediates transformation by oncogenic Dbl through specific membrane targeting. J. Biol. Chem. 271, 19017-19020 (Pubitemid 26271555)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.32
, pp. 19017-19020
-
-
Zheng, Y.1
Zangrilli, D.2
Cerione, R.A.3
Eva, A.4
-
6
-
-
0030010092
-
The Dbl family of oncogenes
-
DOI 10.1016/S0955-0674(96)80068-8
-
Cerione, R. A., and Zheng, Y. (1996) The Dbl family of oncogenes. Curr. Opin. Cell Biol. 8, 216-222 (Pubitemid 26109095)
-
(1996)
Current Opinion in Cell Biology
, vol.8
, Issue.2
, pp. 216-222
-
-
Cerione, R.A.1
Zheng, Y.2
-
7
-
-
0035668525
-
Dbl family guanine nucleotide exchange factors
-
Zheng, Y. (2001) Dbl family guanine nucleotide exchange factors. Trends Biochem. Sci. 26, 724-732
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 724-732
-
-
Zheng, Y.1
-
8
-
-
13444252631
-
GEF means go: Turning on Rho GTPases with guanine nucleotide-exchange factors
-
DOI 10.1038/nrm1587
-
Rossman, K. L., Der, C. J., and Sondek, J. (2005) GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat. Rev. Mol. Cell Biol. 6, 167-180 (Pubitemid 40215811)
-
(2005)
Nature Reviews Molecular Cell Biology
, vol.6
, Issue.2
, pp. 167-180
-
-
Rossman, K.L.1
Der, C.J.2
Sondek, J.3
-
9
-
-
0031041282
-
Dbl family proteins
-
DOI 10.1016/S0304-419X(96)00040-6, PII S0304419X96000406
-
Whitehead, I. P., Campbell, S., Rossman, K. L., and Der, C. J. (1997) Dbl family proteins. Biochim. Biophys. Acta 1332, F1-F23 (Pubitemid 27112552)
-
(1997)
Biochimica et Biophysica Acta - Reviews on Cancer
, vol.1332
, Issue.1
-
-
Whitehead, I.P.1
Campbell, S.2
Rossman, K.L.3
Der, C.J.4
-
10
-
-
0035313804
-
Multiple roles for Cdc42 in cell regulation
-
DOI 10.1016/S0955-0674(00)00192-7
-
Erickson, J. W., and Cerione, R. A. (2001) Multiple roles for Cdc42 in cell regulation. Curr. Opin. Cell Biol. 13, 153-157 (Pubitemid 32209215)
-
(2001)
Current Opinion in Cell Biology
, vol.13
, Issue.2
, pp. 153-157
-
-
Erickson, J.W.1
Cerione, R.A.2
-
11
-
-
0028126564
-
Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: A putative Rho/Rac guanine nucleotide exchange factor
-
Pasteris, N. G., Cadle, A., Logie, L. J., Porteous, M. E., Schwartz, C. E., Stevenson, R. E., Glover, T. W., Wilroy, R. S., and Gorski, J. L. (1994) Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor. Cell 79, 669-678
-
(1994)
Cell
, vol.79
, pp. 669-678
-
-
Pasteris, N.G.1
Cadle, A.2
Logie, L.J.3
Porteous, M.E.4
Schwartz, C.E.5
Stevenson, R.E.6
Glover, T.W.7
Wilroy, R.S.8
Gorski, J.L.9
-
12
-
-
0021346853
-
Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22
-
Groffen, J., Stephenson, J. R., Heisterkamp, N., de Klein, A., Bartram, C. R., and Grosveld, G. (1984) Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22. Cell 36, 93-99 (Pubitemid 14155374)
-
(1984)
Cell
, vol.36
, Issue.1
, pp. 93-99
-
-
Groffen, J.1
Stephenson, J.R.2
Heisterkamp, N.3
-
13
-
-
33746171665
-
On autosomal dominant cerebellar ataxia (ADCA) other than polyglutamine diseases, with special reference to chromosome 16q22.1-linked ADCA
-
DOI 10.1111/j.1440-1789.2006.00719.x
-
Ishikawa, K., and Mizusawa, H. (2006) On autosomal dominant cerebellar ataxia (ADCA) other than polyglutamine diseases, with special reference to chromosome 16q22.1-linked ADCA. Neuropathology 26, 352-360 (Pubitemid 44086840)
-
(2006)
Neuropathology
, vol.26
, Issue.4
, pp. 352-360
-
-
Ishikawa, K.1
Mizusawa, H.2
-
14
-
-
22544448383
-
An autosomal dominant cerebellar ataxia linked to chromosome 16q22.1 is associated with a single-nucleotide substitution in the 5′ untranslated region of the gene encoding a protein with spectrin repeat and Rho guanine-nucleotide exchange-factor domains
-
DOI 10.1086/432518
-
Ishikawa, K., Toru, S., Tsunemi, T., Li, M., Kobayashi, K., Yokota, T., Amino, T., Owada, K., Fujigasaki, H., Sakamoto, M., Tomimitsu, H., Takashima, M., Kumagai, J., Noguchi, Y., Kawashima, Y., Ohkoshi, N., Ishida, G., Gomyoda, M., Yoshida, M., Hashizume, Y., Saito, Y., Murayama, S., Yamanouchi, H., Mizutani, T., Kondo, I., Toda, T., and Mizusawa, H. (2005) An autosomal dominant cerebellar ataxia linked to chromosome 16q22.1 is associated with a single-nucleotide substitution in the 5′ untranslated region of the gene encoding a protein with spectrin repeat and rho guanine-nucleotide exchange-factor domains. Am. J. Hum. Genet. 77, 280-296 (Pubitemid 41022710)
-
(2005)
American Journal of Human Genetics
, vol.77
, Issue.2
, pp. 280-296
-
-
Ishikawa, K.1
Toru, S.2
Tsunemi, T.3
Li, M.4
Kobayashi, K.5
Yokota, T.6
Amino, T.7
Owada, K.8
Fujigasaki, H.9
Sakamoto, M.10
Tomimitsu, H.11
Takashima, M.12
Kumagai, J.13
Noguchi, Y.14
Kawashima, Y.15
Ohkoshi, N.16
Ishida, G.17
Gomyoda, M.18
Yoshida, M.19
Hashizume, Y.20
Saito, Y.21
Murayama, S.22
Yamanouchi, H.23
Mizutani, T.24
Kondo, I.25
Toda, T.26
Mizusawa, H.27
more..
-
15
-
-
78650755927
-
P-Rex1, a guanine exchange factor that is overexpressed in breast cancer, is a convergence node for ErbB and CXCR4 signaling
-
Hynes, N. E., and Gattelli, A. (2011) P-Rex1, a guanine exchange factor that is overexpressed in breast cancer, is a convergence node for ErbB and CXCR4 signaling. Mol. Cell 41, 5-7
-
(2011)
Mol. Cell
, vol.41
, pp. 5-7
-
-
Hynes, N.E.1
Gattelli, A.2
-
16
-
-
79953154962
-
Oncogenic activity of Ect2 is regulated through protein kinase C ι-mediated phosphorylation
-
Justilien, V., Jameison, L., Der, C. J., Rossman, K. L., and Fields, A. P. Oncogenic activity of Ect2 is regulated through protein kinase C ι-mediated phosphorylation. J. Biol. Chem. 286, 8149-8157
-
J. Biol. Chem.
, vol.286
, pp. 8149-8157
-
-
Justilien, V.1
Jameison, L.2
Der, C.J.3
Rossman, K.L.4
Fields, A.P.5
-
17
-
-
77955299128
-
The guanine nucleotide exchange factor (GEF) Ect2 is an oncogene in human cancer
-
Fields, A. P., and Justilien, V. The guanine nucleotide exchange factor (GEF) Ect2 is an oncogene in human cancer. Adv. Enzyme Regul. 50, 190-200
-
Adv. Enzyme Regul.
, vol.50
, pp. 190-200
-
-
Fields, A.P.1
Justilien, V.2
-
18
-
-
78149234118
-
miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells
-
Cottonham, C. L., Kaneko, S., and Xu, L. miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells. J. Biol. Chem. 285, 35293-35302
-
J. Biol. Chem.
, vol.285
, pp. 35293-35302
-
-
Cottonham, C.L.1
Kaneko, S.2
Xu, L.3
-
19
-
-
33751198483
-
Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells
-
Minard, M. E., Ellis, L. M., and Gallick, G. E. (2006) Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells. Clin. Exp. Metastasis 23, 301-313
-
(2006)
Clin. Exp. Metastasis
, vol.23
, pp. 301-313
-
-
Minard, M.E.1
Ellis, L.M.2
Gallick, G.E.3
-
20
-
-
17844400108
-
The guanine nucleotide exchange factor Tiam1 increases colon carcinoma growth at metastatic sites in an orthotopic nude mouse model
-
DOI 10.1038/sj.onc.1208503
-
Minard, M. E., Herynk, M. H., Collard, J. G., and Gallick, G. E. (2005) The guanine nucleotide exchange factor Tiam1 increases colon carcinoma growth at metastatic sites in an orthotopic nude mouse model. Oncogene 24, 2568-2573 (Pubitemid 40593047)
-
(2005)
Oncogene
, vol.24
, Issue.15
, pp. 2568-2573
-
-
Minard, M.E.1
Herynk, M.H.2
Collard, J.G.3
Gallick, G.E.4
-
21
-
-
0024307925
-
Expression of the dbl proto-oncogene in Ewing's sarcomas
-
Vecchio, G., Cavazzana, A. O., Triche, T. J., Ron, D., Reynolds, C. P., and Eva, A. (1989) Expression of the dbl proto-oncogene in Ewing's sarcomas. Oncogene 4, 897-900 (Pubitemid 19176978)
-
(1989)
Oncogene
, vol.4
, Issue.7
, pp. 897-900
-
-
Vecchio, G.1
Cavazzana, A.O.2
Triche, T.J.3
Ron, D.4
Reynolds, C.P.5
Eva, A.6
-
22
-
-
0025560919
-
Preferential expression of the dbl proto-oncogene in some neuroectodermal tumors
-
Colucci-D'Amato, G. L., De Franciscis, V., Rosati, R., Mauro, A., Bulfone, A., Eva, A., and Vecchio, G. (1990) Preferential expression of the dbl proto-oncogene in some neuroectodermal tumors. J. Neurosurg. Sci. 34, 187-188
-
(1990)
J. Neurosurg. Sci.
, vol.34
, pp. 187-188
-
-
Colucci-D'Amato, G.L.1
De Franciscis, V.2
Rosati, R.3
Mauro, A.4
Bulfone, A.5
Eva, A.6
Vecchio, G.7
-
23
-
-
0027295954
-
dbl Oncogene expression in childhood tumors and tumor cell lines
-
Navarro, S., Pellín, A., Noguera, R., Díaz, M. P., Tsokos, M., Triche, T. J., and Llombart-Bosch, A. (1993) dbl oncogene expression in childhood tumors and tumor cell lines. Diagn. Mol. Pathol. 2, 158-162 (Pubitemid 23252433)
-
(1993)
Diagnostic Molecular Pathology
, vol.2
, Issue.3
, pp. 158-162
-
-
Navarro, S.1
Pellin, A.2
Noguera, R.3
Diaz, M.P.4
Tsokos, M.5
Triche, T.J.6
Llombart-, B.A.7
-
24
-
-
0029002525
-
Co-regulated expression of dbl and poly(ADP-ribose) polymerase in Ewing's sarcoma cells and dbl-transformed NIH3T3 fibroblasts
-
Velasco, J. A., Ramsamooj, P., Thraves, P. J., Eva, A., Dritschilo, A., and Notario, V. (1995) Co-regulated expression of dbl and poly(ADP-ribose) polymerase in Ewing's sarcoma cells and dbl-transformed NIH3T3 fibroblasts. Oncogene 10, 2253-2258
-
(1995)
Oncogene
, vol.10
, pp. 2253-2258
-
-
Velasco, J.A.1
Ramsamooj, P.2
Thraves, P.J.3
Eva, A.4
Dritschilo, A.5
Notario, V.6
-
25
-
-
0035138272
-
Autoinhibition mechanism of proto-Dbl
-
DOI 10.1128/MCB.21.5.1463-1474.2001
-
Bi, F., Debreceni, B., Zhu, K., Salani, B., Eva, A., and Zheng, Y. (2001) Autoinhibition mechanism of proto-Dbl. Mol. Cell Biol. 21, 1463-1474 (Pubitemid 32156366)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.5
, pp. 1463-1474
-
-
Bi, F.1
Debreceni, B.2
Zhu, K.3
Salani, B.4
Eva, A.5
Zheng, Y.6
-
26
-
-
33847222687
-
Regulation of proto-oncogenic dbl by chaperone-controlled, ubiquitin-mediated degradation
-
PMC1820456
-
Kamynina, E., Kauppinen, K., Duan, F., Muakkassa, N., and Manor, D. (2007) Regulation of proto-oncogenic dbl by chaperone-controlled, ubiquitin-mediated degradation. Mol. Cell Biol. 27, 1809-1822; PMC1820456
-
(2007)
Mol. Cell Biol.
, vol.27
, pp. 1809-1822
-
-
Kamynina, E.1
Kauppinen, K.2
Duan, F.3
Muakkassa, N.4
Manor, D.5
-
27
-
-
20444426841
-
Regulation of the Dbl proto-oncogene by heat shock cognate protein 70 (Hsc70)
-
DOI 10.1074/jbc.M413984200
-
Kauppinen, K. P., Duan, F., Wels, J. I., and Manor, D. (2005) Regulation of the Dbl proto-oncogene by heat shock cognate protein 70 (Hsc70). J. Biol. Chem. 280, 21638-21644 (Pubitemid 40805733)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.22
, pp. 21638-21644
-
-
Kauppinen, K.P.1
Duan, F.2
Wels, J.I.3
Manor, D.4
-
28
-
-
0027944055
-
Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using fluorescence spectroscopy
-
DOI 10.1021/bi00206a040
-
Leonard, D. A., Evans, T., Hart, M., Cerione, R. A., and Manor, D. (1994) Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using fluorescence spectroscopy. Biochemistry 33, 12323-12328 (Pubitemid 24328053)
-
(1994)
Biochemistry
, vol.33
, Issue.40
, pp. 12323-12328
-
-
Leonard, D.A.1
Evans, T.2
Hart, M.3
Cerione, R.A.4
Manor, D.5
-
29
-
-
0027958423
-
Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product
-
Hart, M. J., Eva, A., Zangrilli, D., Aaronson, S. A., Evans, T., Cerione, R. A., and Zheng, Y. (1994) Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product. J. Biol. Chem. 269, 62-65 (Pubitemid 24026623)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.1
, pp. 62-65
-
-
Hart, M.J.1
Eva, A.2
Zangrilli, D.3
Aaronson, S.A.4
Evans, T.5
Cerione, R.A.6
Zheng, Y.7
-
30
-
-
0025010979
-
The GTPase superfamily: A conserved switch for diverse cell functions
-
Bourne, H. R., Sanders, D. A., and McCormick, F. (1990) The GTPase superfamily: a conserved switch for diverse cell functions. Nature 348, 125-132
-
(1990)
Nature
, vol.348
, pp. 125-132
-
-
Bourne, H.R.1
Sanders, D.A.2
McCormick, F.3
-
31
-
-
0026026818
-
The GTPase superfamily: Conserved structure and molecular mechanism
-
Bourne, H. R., Sanders, D. A., and McCormick, F. (1991) The GTPase superfamily: conserved structure and molecular mechanism. Nature 349, 117-127 (Pubitemid 21912023)
-
(1991)
Nature
, vol.349
, Issue.6305
, pp. 117-127
-
-
Bourne, H.R.1
Sanders, D.A.2
McCormick, F.3
-
32
-
-
0030711709
-
Interaction between Cdc42Hs and RhoGDI is mediated through the Rho insert region
-
Wu, W. J., Leonard, D. A., A-Cerione, R., and Manor, D. (1997) Interaction between Cdc42Hs and RhoGDI is mediated through the Rho insert region. J. Biol. Chem. 272, 26153-26158
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26153-26158
-
-
Wu, W.J.1
Leonard, D.A.2
A-Cerione, R.3
Manor, D.4
-
33
-
-
0028875683
-
Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation
-
Bagrodia, S., Dérijard, B., Davis, R. J., and Cerione, R. A. (1995) Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation. J. Biol. Chem. 270, 27995-27998
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27995-27998
-
-
Bagrodia, S.1
Dérijard, B.2
Davis, R.J.3
Cerione, R.A.4
-
34
-
-
0033777071
-
Determination of GTP loading on Rho
-
Ren, X. D., and Schwartz, M. A. (2000) Determination of GTP loading on Rho. Methods Enzymol. 325, 264-272
-
(2000)
Methods Enzymol.
, vol.325
, pp. 264-272
-
-
Ren, X.D.1
Schwartz, M.A.2
-
35
-
-
0030461098
-
Cell cycle-dependent activation of Ras
-
Taylor, S. J., and Shalloway, D. (1996) Cell cycle-dependent activation of Ras. Curr. Biol. 6, 1621-1627 (Pubitemid 27050229)
-
(1996)
Current Biology
, vol.6
, Issue.12
, pp. 1621-1627
-
-
Taylor, S.J.1
Shalloway, D.2
-
36
-
-
2942564430
-
Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence
-
DOI 10.1002/pmic.200300771
-
Blom, N., Sicheritz-Pontén, T., Gupta, R., Gammeltoft, S., and Brunak, S. (2004) Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence. Proteomics 4, 1633-1649 (Pubitemid 38738322)
-
(2004)
Proteomics
, vol.4
, Issue.6
, pp. 1633-1649
-
-
Blom, N.1
Sicheritz-Ponten, T.2
Gupta, R.3
Gammeltoft, S.4
Brunak, S..5
-
37
-
-
0027957728
-
The GRB2/Sem-5 adaptor protein
-
Downward, J. (1994) The GRB2/Sem-5 adaptor protein. FEBS Lett. 338, 113-117
-
(1994)
FEBS Lett.
, vol.338
, pp. 113-117
-
-
Downward, J.1
-
38
-
-
0027304731
-
Human Sos1: A guanine nucleotide exchange factor for Ras that binds to GRB2
-
Chardin, P., Camonis, J. H., Gale, N. W., van Aelst, L., Schlessinger, J., Wigler, M. H., and Bar-Sagi, D. (1993) Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. Science 260, 1338-1343 (Pubitemid 23231980)
-
(1993)
Science
, vol.260
, Issue.5112
, pp. 1338-1343
-
-
Chardin, P.1
Camonis, J.H.2
Gale, N.W.3
Van Aelst, L.4
Schlessinger, J.5
Wigler, M.H.6
Bar-Sagi, D.7
-
39
-
-
0027229556
-
Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras
-
Gale, N. W., Kaplan, S., Lowenstein, E. J., Schlessinger, J., and Bar-Sagi, D. (1993) Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras. Nature 363, 88-92 (Pubitemid 23144969)
-
(1993)
Nature
, vol.362
, Issue.6424
, pp. 88-92
-
-
Gale, N.W.1
Kaplan, S.2
Lowenstein, E.J.3
Schlessinger, J.4
Bar-Sagi, D.5
-
40
-
-
84866321464
-
Phosphoinositide 3-kinase C2β regulates RhoA and the actin cytoskeleton through an interaction with Dbl
-
Blajecka, K., Marinov, M., Leitner, L., Uth, K., Posern, G., and Arcaro, A. Phosphoinositide 3-kinase C2β regulates RhoA and the actin cytoskeleton through an interaction with Dbl. PLoS One 7, e44945
-
PLoS One
, vol.7
-
-
Blajecka, K.1
Marinov, M.2
Leitner, L.3
Uth, K.4
Posern, G.5
Arcaro, A.6
-
41
-
-
1442290184
-
Epidermal growth factor-dependent regulation of Cdc42 is mediated by the Src tyrosine kinase
-
Tu, S., Wu, W. J., Wang, J., and Cerione, R. A. (2003) Epidermal growth factor-dependent regulation of Cdc42 is mediated by the Src tyrosine kinase. J. Biol. Chem. 278, 49293-49300
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 49293-49300
-
-
Tu, S.1
Wu, W.J.2
Wang, J.3
Cerione, R.A.4
-
42
-
-
0035854826
-
Dbl and the Rho GTPases activate NF κB by I κB kinase (IKK)-dependent and IKK-independent pathways
-
Cammarano, M. S., and Minden, A. (2001) Dbl and the Rho GTPases activate NF κB by I κB kinase (IKK)-dependent and IKK-independent pathways. J. Biol. Chem. 276, 25876-25882
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25876-25882
-
-
Cammarano, M.S.1
Minden, A.2
-
43
-
-
0032557526
-
Multiple signalling pathways lead to the activation of the nuclear factor κB by the Rho family of GTPases
-
DOI 10.1074/jbc.273.21.12779
-
Montaner, S., Perona, R., Saniger, L., and Lacal, J. C. (1998) Multiple signalling pathways lead to the activation of the nuclear factor κB by the Rho family of GTPases. J. Biol. Chem. 273, 12779-12785 (Pubitemid 28246832)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.21
, pp. 12779-12785
-
-
Montaner, S.1
Perona, R.2
Saniger, L.3
Lacal, J.C.4
-
44
-
-
0032695889
-
Dependence of Dbl and Dbs transformation on MEK and NF-κB activation
-
Whitehead, I. P., Lambert, Q. T., Glaven, J. A., Abe, K., Rossman, K. L., Mahon, G. M., Trzaskos, J. M., Kay, R., Campbell, S. L., and Der, C. J. (1999) Dependence of Dbl and Dbs transformation on MEK and NF-κB activation. Mol. Cell Biol. 19, 7759-7770 (Pubitemid 29493440)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.11
, pp. 7759-7770
-
-
Whitehead, I.P.1
Lambert, Q.T.2
Glaven, J.A.3
Abe, K.4
Rossman, K.L.5
Mahon, G.M.6
Trzaskos, J.M.7
Kay, R.8
Campbell, S.L.9
Der, C.J.10
-
45
-
-
0024062724
-
Molecular cloning and characterization of the human Dbl proto-oncogene: Evidence that its overexpression is sufficient to transform NIH/3T3 cells
-
Ron, D., Tronick, S. R., Aaronson, S. A., and Eva, A. (1988) Molecular cloning and characterization of the human Dbl proto-oncogene: evidence that its overexpression is sufficient to transform NIH/3T3 cells. EMBO J. 7, 2465-2473
-
(1988)
EMBO J.
, vol.7
, pp. 2465-2473
-
-
Ron, D.1
Tronick, S.R.2
Aaronson, S.A.3
Eva, A.4
-
46
-
-
0025758833
-
A region of proto-dbl essential for its transforming activity shows sequence similarity to a yeast cell cycle gene, CDC24, and the human breakpoint cluster gene, bcr
-
Ron, D., Zannini, M., Lewis, M., Wickner, R. B., Hunt, L. T., Graziani, G., Tronick, S. R., Aaronson, S. A., and Eva, A. (1991) A region of proto-dbl essential for its transforming activity shows sequence similarity to a yeast cell cycle gene, CDC24, and the human breakpoint cluster gene, bcr. New Biol. 3, 372-379
-
(1991)
New Biol.
, vol.3
, pp. 372-379
-
-
Ron, D.1
Zannini, M.2
Lewis, M.3
Wickner, R.B.4
Hunt, L.T.5
Graziani, G.6
Tronick, S.R.7
Aaronson, S.A.8
Eva, A.9
-
47
-
-
0028075246
-
Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic ras
-
Khosravi-Far, R., Chrzanowska-Wodnicka, M., Solski, P. A., Eva, A., Burridge, K., and Der, C. J. (1994) Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras. Mol. Cell Biol. 14, 6848-6857 (Pubitemid 24299754)
-
(1994)
Molecular and Cellular Biology
, vol.14
, Issue.10
, pp. 6848-6857
-
-
Khosravi-Far, R.1
Chrzanowska-Wodnicka, M.2
Solski, P.A.3
Eva, A.4
Burridge, K.5
Der, C.J.6
-
48
-
-
0027052132
-
Ras-related GTPases and the cytoskeleton
-
Hall, A. (1992) Ras-related GTPases and the cytoskeleton. Mol. Biol. Cell 3, 475-479
-
(1992)
Mol. Biol. Cell
, vol.3
, pp. 475-479
-
-
Hall, A.1
-
49
-
-
0026995829
-
Distinct patterns of actin organization regulated by the small GTP-binding proteins Rac and Rho
-
Ridley, A. J., and Hall, A. (1992) Distinct patterns of actin organization regulated by the small GTP-binding proteins Rac and Rho. Cold Spring Harb. Symp. Quant Biol. 57, 661-671
-
(1992)
Cold Spring Harb. Symp. Quant Biol.
, vol.57
, pp. 661-671
-
-
Ridley, A.J.1
Hall, A.2
-
50
-
-
0028961293
-
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
-
Nobes, C. D., and Hall, A. (1995) Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81, 53-62
-
(1995)
Cell
, vol.81
, pp. 53-62
-
-
Nobes, C.D.1
Hall, A.2
-
51
-
-
0033551698
-
Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation
-
Lin, R., Cerione, R. A., and Manor, D. (1999) Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation. J. Biol. Chem. 274, 23633-23641
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 23633-23641
-
-
Lin, R.1
Cerione, R.A.2
Manor, D.3
-
52
-
-
16244413928
-
Larger than Dbl: New structural insights into RhoA activation
-
DOI 10.1016/j.tibs.2005.02.002
-
Rossman, K. L., Sondek J. (2005) Larger than Dbl: new structural insights into RhoA activation. Trends Biochem. Sci. 30, 163-165 (Pubitemid 40463302)
-
(2005)
Trends in Biochemical Sciences
, vol.30
, Issue.4
, pp. 163-165
-
-
Rossman, K.L.1
Sondek, J.2
-
53
-
-
1442274703
-
Cdc42: New roads to travel
-
Cerione, R. A. (2004) Cdc42: new roads to travel. Trends Cell Biol. 14, 127-132
-
(2004)
Trends Cell Biol.
, vol.14
, pp. 127-132
-
-
Cerione, R.A.1
-
54
-
-
0001264854
-
The γ-subunit of the coatomer complex binds Cdc42 to mediate transformation
-
DOI 10.1038/35015585
-
Wu, W. J., Erickson, J. W., Lin, R., and Cerione, R. A. (2000) The γ-subunit of the coatomer complex binds Cdc42 to mediate transformation. Nature 405, 800-804 (Pubitemid 30407853)
-
(2000)
Nature
, vol.405
, Issue.6788
, pp. 800-804
-
-
Wu, W.J.1
Erickson, J.W.2
Lin, R.3
Cerione, R.A.4
-
55
-
-
60349115007
-
Vav1: A hematopoietic signal transduction molecule involved in human malignancies
-
Katzav, S. (2009) Vav1: a hematopoietic signal transduction molecule involved in human malignancies. Int. J. Biochem. Cell Biol. 41, 1245-1248
-
(2009)
Int. J. Biochem. Cell Biol.
, vol.41
, pp. 1245-1248
-
-
Katzav, S.1
-
56
-
-
18844449626
-
Vav-family proteins in T-cell signalling
-
Tybulewicz, V. L. (2005) Vav-family proteins in T-cell signalling. Curr. Opin. Immunol. 17, 267-274
-
(2005)
Curr. Opin. Immunol.
, vol.17
, pp. 267-274
-
-
Tybulewicz, V.L.1
-
57
-
-
46049103579
-
Role of the C-terminal SH3 domain and N-terminal tyrosine phosphorylation in regulation of Tim and related Dbl-family proteins
-
DOI 10.1021/bi702543p
-
Yohe, M. E., Rossman, K., and Sondek, J. (2008) Role of the C-terminal SH3 domain and N-terminal tyrosine phosphorylation in regulation of Tim and related Dbl-family proteins. Biochemistry 47, 6827-6839 (Pubitemid 351898938)
-
(2008)
Biochemistry
, vol.47
, Issue.26
, pp. 6827-6839
-
-
Yohe, M.E.1
Rossman, K.2
Sondek, J.3
-
58
-
-
67649523534
-
On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF
-
Zheng, M., Cierpicki, T., Momotani, K., Artamonov, M. V., Derewenda, U., Bushweller, J. H., Somlyo, A. V., and Derewenda, Z. S. (2009) On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF. BMC Struct. Biol. 9, 36
-
(2009)
BMC Struct. Biol.
, vol.9
, pp. 36
-
-
Zheng, M.1
Cierpicki, T.2
Momotani, K.3
Artamonov, M.V.4
Derewenda, U.5
Bushweller, J.H.6
Somlyo, A.V.7
Derewenda, Z.S.8
-
59
-
-
78650777435
-
Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF
-
Chen, Z., Guo, L., Sprang, S. R., and Sternweis, P. C. (2011) Modulation of a GEF switch: autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF. Protein Sci. 20, 107-117
-
(2011)
Protein Sci.
, vol.20
, pp. 107-117
-
-
Chen, Z.1
Guo, L.2
Sprang, S.R.3
Sternweis, P.C.4
-
60
-
-
64149093844
-
Activation of leukemia-associated RhoGEF by Gα13 with significant conformational rearrangements in the interface
-
Suzuki, N., Tsumoto, K., Hajicek, N., Daigo, K., Tokita, R., Minami, S., Kodama, T., Hamakubo, T., and Kozasa, T. (2009) Activation of leukemia-associated RhoGEF by Gα13 with significant conformational rearrangements in the interface. J. Biol. Chem. 284, 5000-5009
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 5000-5009
-
-
Suzuki, N.1
Tsumoto, K.2
Hajicek, N.3
Daigo, K.4
Tokita, R.5
Minami, S.6
Kodama, T.7
Hamakubo, T.8
Kozasa, T.9
-
61
-
-
2942535830
-
Phosphorylation-independent membrane relocalization of ezrin following association with Dbl in vivo
-
Vanni, C., Parodi, A., Mancini, P., Visco, V., Ottaviano, C., Torrisi, M. R., and Eva, A. (2004) Phosphorylation-independent membrane relocalization of ezrin following association with Dbl in vivo. Oncogene 23, 4098-4106
-
(2004)
Oncogene
, vol.23
, pp. 4098-4106
-
-
Vanni, C.1
Parodi, A.2
Mancini, P.3
Visco, V.4
Ottaviano, C.5
Torrisi, M.R.6
Eva, A.7
|