Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling

International Journal of Cancer

Volumn 135, Issue 5, 2014, Pages 1110-1118

  Nones, Katia ^a   Waddell, Nic ^a   Song, Sarah ^a   Patch, Ann Marie ^a   Miller, David ^a   Johns, Amber ^b   Wu, Jianmin ^b   Kassahn, Karin S ^a   Wood, David ^a   Bailey, Peter ^a   Fink, Lynn ^a   Manning, Suzanne ^a   Christ, Angelika N ^a   Nourse, Craig ^a   Kazakoff, Stephen ^a   Taylor, Darrin ^a   Leonard, Conrad ^a   Chang, David K ^b,c,d,e   Jones, Marc D ^b   Thomas, Michelle ^b   Watson, Clare ^b   Pinese, Mark ^b   Cowley, Mark ^b   Rooman, Ilse ^b   Pajic, Marina ^b   Butturini, Giovanni ^f   Malpaga, Anna ^f   Corbo, Vincenzo ^g   Crippa, Stefano ^h   Falconi, Massimo ⁱ   Zamboni, Giuseppe ⁱ   Castelli, Paola ^h   Lawlor, Rita T ^g,i   Gill, Anthony J ^b,j   Scarpa, Aldo ^g,i   Pearson, John V ^a   Biankin, Andrew V ^b,c,d,e   Grimmond, Sean M ^a,e   more..

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c BANKSTOWN LIDCOMBE HOSPITAL   (Australia)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

^e UNIVERSITY OF GLASGOW   (United Kingdom)

^f UNIVERSITY OF VERONA   (Italy)

^g University and Hospital Trust of Verona   (Italy)

^h SACRO CUORE DON CALABRIA HOSPITAL   (Italy)

ⁱ UNIVERSITY HOSPITAL OF VERONA   (Italy)

^j UNIVERSITY OF SYDNEY   (Australia)

more..

Author keywords

axon guidance; methylation; pancreatic cancer; SLIT ROBO pathway; stellate cell activation

Indexed keywords

MESSENGER RNA;

5' UNTRANSLATED REGION; ARTICLE; CANCER SURVIVAL; CARCINOGENESIS; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EPIGENETICS; GENE; GENE EXPRESSION; GENETIC IDENTIFICATION; GENETIC REGULATION; GENOME; HUMAN; HUMAN TISSUE; ITGA2 GENE; MET GENE; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; PROMOTER REGION; ROBO GENE; SIGNAL TRANSDUCTION; SLIT GENE;

AXON-GUIDANCE; METHYLATION; PANCREATIC CANCER; SLIT-ROBO PATHWAY; STELLATE CELL ACTIVATION;

ADULT; AGED; AGED, 80 AND OVER; BASE SEQUENCE; CARCINOMA, PANCREATIC DUCTAL; CELL ADHESION; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTEGRIN ALPHA2; INTEGRINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; NERVE TISSUE PROTEINS; PANCREATIC DUCTS; PANCREATIC NEOPLASMS; PANCREATIC STELLATE CELLS; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-MET; RECEPTORS, IMMUNOLOGIC; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEINS;

EID: 84902438252     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28765     Document Type: Article

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