Bromodeoxyuridine (BrdU) treatment to measure hepatocellular proliferation does not mask furan-induced gene expression changes in mouse liver

Toxicology

Volumn 323, Issue , 2014, Pages 26-31

  Webster, Anna Francina ^a,b   Williams, Andrew ^a   Recio, Leslie ^c   Yauk, Carole L ^a  

^a HEALTH CANADA   (Canada)

^b CARLETON UNIVERSITY   (Canada)

^c ILS Inc   (United States)

Author keywords

Bromodeoxyuridine (BrdU); Furan; Gene expression; Toxicogenomics

Indexed keywords

BROXURIDINE; CARCINOGEN; DNA; DRINKING WATER; FURAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL COUNT; CELL PROLIFERATION; CONTROLLED STUDY; DNA MICROARRAY; DRUG EXPOSURE; DRUG MEGADOSE; FEMALE; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; LIVER; LIVER CELL; LIVER TOXICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RODENT; TOXICITY TESTING; TOXICOGENETICS;

BROMODEOXYURIDINE (BRDU); FURAN; GENE EXPRESSION; TOXICOGENOMICS;

ANIMALS; BROMODEOXYURIDINE; CARCINOGENS; CELL PROLIFERATION; FEMALE; FURANS; GENE EXPRESSION PROFILING; LIVER; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA;

EID: 84902435998     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2014.06.002     Document Type: Article

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