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Volumn 9, Issue 1, 2014, Pages 2879-2889

TAT-LHRH conjugated low molecular weight chitosan as a gene carrier specific for hepatocellular carcinoma cells

Author keywords

Cancer treatment; Gene therapy; Hepatoma; Nanoparticles; Targeted gene delivery

Indexed keywords

CHITOSAN; GONADORELIN; TRANSACTIVATOR PROTEIN; DNA; NANOCAPSULE; NANOCONJUGATE;

EID: 84902361992     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S61392     Document Type: Article
Times cited : (31)

References (44)
  • 1
    • 0036829856 scopus 로고    scopus 로고
    • Hepatocellular carcinoma and hepatitis C in the United States
    • El-Serag HB. Hepatocellular carcinoma and hepatitis C in the United States. Hepatology. 2002; 36(5 Suppl 1): S74-S83.
    • (2002) Hepatology , vol.36 , Issue.5 SUPPL. 1
    • El-Serag, H.B.1
  • 2
    • 84866656258 scopus 로고    scopus 로고
    • The prospects of HPV vaccination in cervical cancer prevention: Results of a new independent trial
    • Bosch FX, de Sanjose S, Castellsague X. The prospects of HPV vaccination in cervical cancer prevention: results of a new independent trial. Cancer Discov. 2011;1(5):377-380.
    • (2011) Cancer Discov , vol.1 , Issue.5 , pp. 377-380
    • Bosch, F.X.1    de Sanjose, S.2    Castellsague, X.3
  • 3
    • 54449083925 scopus 로고    scopus 로고
    • Molecular targeted therapies in hepatocellular carcinoma
    • Llovet JM, Bruix J. Molecular targeted therapies in hepatocellular carcinoma. Hepatology. 2008;48(4):1312-1327.
    • (2008) Hepatology , vol.48 , Issue.4 , pp. 1312-1327
    • Llovet, J.M.1    Bruix, J.2
  • 4
    • 49649083138 scopus 로고    scopus 로고
    • Adenovirus-delivered CIAPIN1 small interfering RNA inhibits HCC growth in vitro and in vivo
    • Li X, Pan Y, Fan R, et al. Adenovirus-delivered CIAPIN1 small interfering RNA inhibits HCC growth in vitro and in vivo. Carcinogenesis. 2008;29(8):1587-1593.
    • (2008) Carcinogenesis , vol.29 , Issue.8 , pp. 1587-1593
    • Li, X.1    Pan, Y.2    Fan, R.3
  • 5
    • 44349142671 scopus 로고    scopus 로고
    • Trends in local therapy for hepatocellular carcinoma and survival outcomes in the US population
    • Schwarz RE, Smith DD. Trends in local therapy for hepatocellular carcinoma and survival outcomes in the US population. Am J Surg. 2008;195(6):829-836.
    • (2008) Am J Surg , vol.195 , Issue.6 , pp. 829-836
    • Schwarz, R.E.1    Smith, D.D.2
  • 6
    • 84874491856 scopus 로고    scopus 로고
    • Improving outcomes with surgical resection and other ablative therapies in HCC
    • Deshpande R, O'Reilly D, Sherlock D. Improving outcomes with surgical resection and other ablative therapies in HCC. Int J Hepatol. 2011;2011:686074.
    • (2011) Int J Hepatol , vol.2011 , pp. 686074
    • Deshpande, R.1    O'Reilly, D.2    Sherlock, D.3
  • 7
    • 0141491273 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • Llovet JM, Burroughs A, Bruix J. Hepatocellular carcinoma. Lancet. 2003;362(9399):1907-1917.
    • (2003) Lancet , vol.362 , Issue.9399 , pp. 1907-1917
    • Llovet, J.M.1    Burroughs, A.2    Bruix, J.3
  • 8
    • 0029364399 scopus 로고
    • Cancer prevention: New challenges and opportunities
    • Levin B. Cancer prevention: new challenges and opportunities. Curr Opin Oncol. 1995;7(5):397.
    • (1995) Curr Opin Oncol , vol.7 , Issue.5 , pp. 397
    • Levin, B.1
  • 9
    • 0034090264 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • Okuda K. Hepatocellular carcinoma. J Hepatol. 2000;32(1 Suppl):225-237.
    • (2000) J Hepatol , vol.32 , Issue.1 SUPPL. , pp. 225-237
    • Okuda, K.1
  • 10
    • 40849124295 scopus 로고    scopus 로고
    • Novel advancements in the management of hepatocellular carcinoma in
    • Llovet JM, Bruix J. Novel advancements in the management of hepatocellular carcinoma in 2008. J Hepatol. 2008;48 Suppl 1:S20-S37.
    • (2008) J Hepatol , vol.48 , Issue.SUPPL. 1
    • Llovet, J.M.1    Bruix, J.2
  • 11
    • 41849137252 scopus 로고    scopus 로고
    • Harnessing the RNA interference pathway to advance treatment and prevention of hepatocellular carcinoma
    • Arbuthnot P, Thompson LJ. Harnessing the RNA interference pathway to advance treatment and prevention of hepatocellular carcinoma. World J Gastroenterol. 2008;14(11):1670-1681.
    • (2008) World J Gastroenterol , vol.14 , Issue.11 , pp. 1670-1681
    • Arbuthnot, P.1    Thompson, L.J.2
  • 12
    • 84879093945 scopus 로고    scopus 로고
    • Self-assembled nanoparticles based on modified cationic dipeptides and DNA: Novel systems for gene delivery
    • Panda JJ, Varshney A, Chauhan VS. Self-assembled nanoparticles based on modified cationic dipeptides and DNA: novel systems for gene delivery. J Nanobiotechnology. 2013;11:18.
    • (2013) J Nanobiotechnology , vol.11 , pp. 18
    • Panda, J.J.1    Varshney, A.2    Chauhan, V.S.3
  • 13
    • 79953325093 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-targeted (131)I-therapy of liver cancer following systemic delivery of the sodium iodide symporter gene
    • Klutz K, Schaffert D, Willhauck MJ, et al. Epidermal growth factor receptor-targeted (131)I-therapy of liver cancer following systemic delivery of the sodium iodide symporter gene. Mol Ther. 2011;19(4):676-685.
    • (2011) Mol Ther , vol.19 , Issue.4 , pp. 676-685
    • Klutz, K.1    Schaffert, D.2    Willhauck, M.J.3
  • 14
    • 84869816494 scopus 로고    scopus 로고
    • Galactosylated chitosan/5-fluorouracil nanoparticles inhibit mouse hepatic cancer growth and its side effects
    • Cheng MR, Li Q, Wan T, et al. Galactosylated chitosan/5-fluorouracil nanoparticles inhibit mouse hepatic cancer growth and its side effects. World J Gastroenterol. 2012;18(42):6076-6087.
    • (2012) World J Gastroenterol , vol.18 , Issue.42 , pp. 6076-6087
    • Cheng, M.R.1    Li, Q.2    Wan, T.3
  • 15
    • 84865416584 scopus 로고    scopus 로고
    • Targeted delivery of chemotherapy agents using a liver cancer-specific aptamer
    • Meng L, Yang L, Zhao X, et al. Targeted delivery of chemotherapy agents using a liver cancer-specific aptamer. PLoS One. 2012;7(4):e33434.
    • (2012) PLoS One , vol.7 , Issue.4
    • Meng, L.1    Yang, L.2    Zhao, X.3
  • 16
    • 0038377441 scopus 로고    scopus 로고
    • Enhancing the efficacy of chemotherapeutic drugs by the suppression of antiapoptotic cellular defense
    • Minko T, Dharap SS, Fabbricatore AT. Enhancing the efficacy of chemotherapeutic drugs by the suppression of antiapoptotic cellular defense. Cancer Detect Prev. 2003;27(3):193-202.
    • (2003) Cancer Detect Prev , vol.27 , Issue.3 , pp. 193-202
    • Minko, T.1    Dharap, S.S.2    Fabbricatore, A.T.3
  • 17
    • 0141886989 scopus 로고    scopus 로고
    • Molecular targeting of drug delivery systems to ovarian cancer by BH3 and LHRH peptides
    • Dharap SS, Qiu B, Williams GC, Sinko P, Stein S, Minko T. Molecular targeting of drug delivery systems to ovarian cancer by BH3 and LHRH peptides. J Control Release. 2003;91(1-2):61-73.
    • (2003) J Control Release , vol.91 , Issue.1-2 , pp. 61-73
    • Dharap, S.S.1    Qiu, B.2    Williams, G.C.3    Sinko, P.4    Stein, S.5    Minko, T.6
  • 18
    • 2342417841 scopus 로고    scopus 로고
    • Molecular targeting of drug delivery systems to cancer
    • Minko T, Dharap SS, Pakunlu RI, Wang Y. Molecular targeting of drug delivery systems to cancer. Curr Drug Targets. 2004;5(4):389-406.
    • (2004) Curr Drug Targets , vol.5 , Issue.4 , pp. 389-406
    • Minko, T.1    Dharap, S.S.2    Pakunlu, R.I.3    Wang, Y.4
  • 19
    • 84869387296 scopus 로고    scopus 로고
    • Selective gene delivery to cancer cells using an integrated cationic amphiphilic peptide
    • Tang Q, Cao B, Wu H, Cheng G. Selective gene delivery to cancer cells using an integrated cationic amphiphilic peptide. Langmuir. 2012;28(46):16126-16132.
    • (2012) Langmuir , vol.28 , Issue.46 , pp. 16126-16132
    • Tang, Q.1    Cao, B.2    Wu, H.3    Cheng, G.4
  • 20
    • 24644496584 scopus 로고    scopus 로고
    • Tumor-specific targeting of ananticancer drug delivery system by LHRH peptide
    • Dharap SS, Wang Y, Chandna P, et al. Tumor-specific targeting of ananticancer drug delivery system by LHRH peptide. Proc Natl Acad Sci U S A. 2005;102(36):12962-12967.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.36 , pp. 12962-12967
    • Dharap, S.S.1    Wang, Y.2    Chandna, P.3
  • 21
    • 0032562410 scopus 로고    scopus 로고
    • Expression of the messenger RNA for gonadotropin-releasing hormone and its receptor in human cancer cell lines
    • Yin H, Cheng KW, Hwa HL, Peng C, Auersperg N, Leung PC. Expression of the messenger RNA for gonadotropin-releasing hormone and its receptor in human cancer cell lines. Life Sci. 1998;62(22):2015-2023.
    • (1998) Life Sci , vol.62 , Issue.22 , pp. 2015-2023
    • Yin, H.1    Cheng, K.W.2    Hwa, H.L.3    Peng, C.4    Auersperg, N.5    Leung, P.C.6
  • 22
    • 47949125820 scopus 로고    scopus 로고
    • Therapy of experimental hepatic cancers with cytotoxic peptide analogs targeted to receptors for luteinizing hormone-releasing hormone, somatostatin or bombesin
    • Szepeshazi K, Schally AV, Treszl A, Seitz S, Halmos G. Therapy of experimental hepatic cancers with cytotoxic peptide analogs targeted to receptors for luteinizing hormone-releasing hormone, somatostatin or bombesin. Anticancer Drugs. 2008;19(4):349-358.
    • (2008) Anticancer Drugs , vol.19 , Issue.4 , pp. 349-358
    • Szepeshazi, K.1    Schally, A.V.2    Treszl, A.3    Seitz, S.4    Halmos, G.5
  • 23
    • 0032484162 scopus 로고    scopus 로고
    • Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery
    • MacLaughlin FC, Mumper RJ, Wang J, et al. Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery. J Control Release. 1998;56(1-3):259-272.
    • (1998) J Control Release , vol.56 , Issue.1-3 , pp. 259-272
    • Maclaughlin, F.C.1    Mumper, R.J.2    Wang, J.3
  • 24
    • 0032990267 scopus 로고    scopus 로고
    • Potential of low molecular mass chitosan as a DNA delivery system: Biocompatibility, body distribution and ability to complex and protect DNA
    • Richardson SC, Kolbe HV, Duncan R. Potential of low molecular mass chitosan as a DNA delivery system: biocompatibility, body distribution and ability to complex and protect DNA. Int J Pharm. 1999; 178(2):231-243.
    • (1999) Int J Pharm , vol.178 , Issue.2 , pp. 231-243
    • Richardson, S.C.1    Kolbe, H.V.2    Duncan, R.3
  • 25
    • 0035936972 scopus 로고    scopus 로고
    • Chitosan-DNA nanoparticles as gene carriers: Synthesis, characterization and transfection efficiency
    • Mao HQ, Roy K, Troung-Le VL, et al. Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency. J Control Release. 2001;70(3):399-421.
    • (2001) J Control Release , vol.70 , Issue.3 , pp. 399-421
    • Mao, H.Q.1    Roy, K.2    Troung-Le, V.L.3
  • 27
    • 84878170578 scopus 로고    scopus 로고
    • Development and characterization of chitosan-PEG-TAT nanoparticles for the intracellular delivery of siRNA
    • Malhotra M, Tomaro-Duchesneau C, Saha S, Kahouli I, Prakash S. Development and characterization of chitosan-PEG-TAT nanoparticles for the intracellular delivery of siRNA. Int J Nanomedicine. 2013;8: 2041-2052.
    • (2013) Int J Nanomedicine , vol.8 , pp. 2041-2052
    • Malhotra, M.1    Tomaro-Duchesneau, C.2    Saha, S.3    Kahouli, I.4    Prakash, S.5
  • 28
    • 84878622079 scopus 로고    scopus 로고
    • Transfection efficiency of chitosan and thiolated chitosan in retinal pigment epithelium cells: A comparative study
    • Oliveira AV, Silva AP, Bitoque DB, Silva GA, Rosa da Costa AM. Transfection efficiency of chitosan and thiolated chitosan in retinal pigment epithelium cells: A comparative study. J Pharm Bioallied Sci. 2013;5(2):111-118.
    • (2013) J Pharm Bioallied Sci , vol.5 , Issue.2 , pp. 111-118
    • Oliveira, A.V.1    Silva, A.P.2    Bitoque, D.B.3    Silva, G.A.4    da Costa, A.M.R.5
  • 29
    • 0031722107 scopus 로고    scopus 로고
    • Chitosan-based vector/DNA complexes for gene delivery: Biophysical characteristics and transfection ability
    • Erbacher P, Zou S, Bettinger T, Steffan AM, Remy JS. Chitosan-based vector/DNA complexes for gene delivery: biophysical characteristics and transfection ability. Pharm Res. 1998;15(9):1332-1339.
    • (1998) Pharm Res , vol.15 , Issue.9 , pp. 1332-1339
    • Erbacher, P.1    Zou, S.2    Bettinger, T.3    Steffan, A.M.4    Remy, J.S.5
  • 30
    • 0037340617 scopus 로고    scopus 로고
    • Mesenchymal stem cells, MG63 and HEK293 transfection using chitosan-DNA nanoparticles
    • Corsi K, Chellat F, Yahia L, Fernandes JC. Mesenchymal stem cells, MG63 and HEK293 transfection using chitosan-DNA nanoparticles. Biomaterials. 2003;24(7):1255-1264.
    • (2003) Biomaterials , vol.24 , Issue.7 , pp. 1255-1264
    • Corsi, K.1    Chellat, F.2    Yahia, L.3    Fernandes, J.C.4
  • 32
    • 84879902991 scopus 로고    scopus 로고
    • Hydrophobin: Fluorosurfactant-like properties without fluorine
    • Milani R, Monogioudi E, Baldrighi M, et al. Hydrophobin: fluorosurfactant-like properties without fluorine. Soft Matter. 2013;9:6505-6514.
    • (2013) Soft Matter , vol.9 , pp. 6505-6514
    • Milani, R.1    Monogioudi, E.2    Baldrighi, M.3
  • 33
    • 84856149567 scopus 로고    scopus 로고
    • Zwitterionic chitosan derivative, a new biocompatible pharmaceutical excipient, prevents endotoxin-mediated cytokine release
    • Bajaj G, Van Alstine WG, Yeo Y. Zwitterionic chitosan derivative, a new biocompatible pharmaceutical excipient, prevents endotoxin-mediated cytokine release. PLoS One. 2012;7(1):e30899.
    • (2012) PLoS One , vol.7 , Issue.1
    • Bajaj, G.1    van Alstine, W.G.2    Yeo, Y.3
  • 34
    • 51049092308 scopus 로고    scopus 로고
    • Factors affecting the clearance and biodistribution of polymeric nanoparticles
    • Alexis F, Pridgen E, Molnar LK, Farokhzad OC. Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol Pharm. 2008;5(4):505-515.
    • (2008) Mol Pharm , vol.5 , Issue.4 , pp. 505-515
    • Alexis, F.1    Pridgen, E.2    Molnar, L.K.3    Farokhzad, O.C.4
  • 35
    • 84878286392 scopus 로고    scopus 로고
    • A dual-functionally modified chitosan derivative for efficient liver-targeted gene delivery
    • Xiao B, Wang X, Qiu Z, et al. A dual-functionally modified chitosan derivative for efficient liver-targeted gene delivery. J Biomed Mater Res A. 2013;101(7):1888-1897.
    • (2013) J Biomed Mater Res A , vol.101 , Issue.7 , pp. 1888-1897
    • Xiao, B.1    Wang, X.2    Qiu, Z.3
  • 36
    • 78649586732 scopus 로고    scopus 로고
    • Evaluation of the impact of arginine-chitosan/DNA nanoparticles on human naive CD4+ T cells
    • Liu L, Bai Y, Zhu D, et al. Evaluation of the impact of arginine-chitosan/DNA nanoparticles on human naive CD4+ T cells. J Biomed Mater Res A. 2011;96(1):170-176.
    • (2011) J Biomed Mater Res A , vol.96 , Issue.1 , pp. 170-176
    • Liu, L.1    Bai, Y.2    Zhu, D.3
  • 38
    • 57149087295 scopus 로고    scopus 로고
    • Effects of molecular weight and concentration of chitosan on antifungal activity against Aspergillus niger
    • Li X-F, Feng X-Q, Yang S, Wang T-P, Su Z-X. Effects of molecular weight and concentration of chitosan on antifungal activity against Aspergillus niger. Iranian Polymer Journal. 2008;17(11):843-852.
    • (2008) Iranian Polymer Journal , vol.17 , Issue.11 , pp. 843-852
    • Li, X.-F.1    Feng, X.-Q.2    Yang, S.3    Wang, T.-P.4    Su, Z.-X.5
  • 39
    • 33645549194 scopus 로고    scopus 로고
    • A special report on the chitosan-based hemostatic dressing: Experience in current combat operations
    • Wedmore I, McManus JG, Pusateri AE, Holcomb JB. A special report on the chitosan-based hemostatic dressing: experience in current combat operations. J Trauma. 2006;60(3):655-658.
    • (2006) J Trauma , vol.60 , Issue.3 , pp. 655-658
    • Wedmore, I.1    McManus, J.G.2    Pusateri, A.E.3    Holcomb, J.B.4
  • 40
    • 84862646294 scopus 로고    scopus 로고
    • Chitosan-based drug nanocarriers: Where do we stand?
    • Garcia-Fuentes M, Alonso MJ. Chitosan-based drug nanocarriers: where do we stand? J Control Release. 2012;161(2):496-504.
    • (2012) J Control Release , vol.161 , Issue.2 , pp. 496-504
    • Garcia-Fuentes, M.1    Alonso, M.J.2
  • 41
    • 75149147526 scopus 로고    scopus 로고
    • Biodegradation, biodistribution and toxicity of chitosan
    • Kean T, Thanou M. Biodegradation, biodistribution and toxicity of chitosan. Adv Drug Deliv Rev. 2010;62(1):3-11.
    • (2010) Adv Drug Deliv Rev , vol.62 , Issue.1 , pp. 3-11
    • Kean, T.1    Thanou, M.2
  • 42
    • 1242314681 scopus 로고    scopus 로고
    • Uptake and cytotoxicity of chitosan molecules and nanoparticles: Effects of molecular weight and degree of deacetylation
    • Huang M, Khor E, Lim LY. Uptake and cytotoxicity of chitosan molecules and nanoparticles: effects of molecular weight and degree of deacetylation. Pharm Res. 2004;21(2):344-353.
    • (2004) Pharm Res , vol.21 , Issue.2 , pp. 344-353
    • Huang, M.1    Khor, E.2    Lim, L.Y.3
  • 43
    • 18744426403 scopus 로고    scopus 로고
    • Cationic liposomes for gene delivery: Novel cationic lipids and enhancement by proteins and peptides
    • Düzgünes N, De Ilarduya CT, Simões S, et al. Cationic liposomes for gene delivery: novel cationic lipids and enhancement by proteins and peptides. Curr Med Chem. 2003;10(14):1213-1220.
    • (2003) Curr Med Chem , vol.10 , Issue.14 , pp. 1213-1220
    • Düzgünes, N.1    de Ilarduya, C.T.2    Simões, S.3
  • 44
    • 0035424424 scopus 로고    scopus 로고
    • In vitro gene delivery mediated by chitosan, effect of pH, serum, and molecular mass of chitosan on the transfection efficiency
    • Sato T, Ishii T, Okahata Y. In vitro gene delivery mediated by chitosan, effect of pH, serum, and molecular mass of chitosan on the transfection efficiency. Biomaterials. 2001;22(15):2075-2080.
    • (2001) Biomaterials , vol.22 , Issue.15 , pp. 2075-2080
    • Sato, T.1    Ishii, T.2    Okahata, Y.3


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