Prevention of organophosphate-induced chronic epilepsy by early benzodiazepine treatment

Toxicology

Volumn 323, Issue , 2014, Pages 19-25

  Shrot, Shai ^a,b   Ramaty, Erez ^a,b   Biala, Yoav ^c   Bar Klein, Guy ^d   Daninos, Moshe ^c   Kamintsky, Lyn ^d   Makarovsky, Igor ^a   Statlender, Liran ^a   Rosman, Yossi ^a,b   Krivoy, Amir ^a,e   Lavon, Ophir ^a   Kassirer, Michael ^a   Friedman, Alon ^d   Yaari, Yoel ^c  

^a Medical Corps   (Israel)

^b SHEBA MEDICAL CENTER   (Israel)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^d BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^e TEL AVIV UNIVERSITY   (Israel)

Author keywords

Epileptogenesis; Midazolam; Neurotoxicity; Paraoxon; Pesticide; Poisoning

Indexed keywords

ACETYLCHOLINESTERASE; ATROPINE; MIDAZOLAM; OBIDOXIME; PARAOXON;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN SLICE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ELECTROCORTICOGRAPHY; ELECTROENCEPHALOGRAM; ENZYME INHIBITION; EPILEPSY; EPILEPTIC STATE; EPILEPTOGENESIS; HIPPOCAMPUS; IN VIVO STUDY; MORTALITY; NERVE CELL EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SEIZURE; SPONTANEOUS RECURRENT SEIZURE; TELEMETRY;

EPILEPTOGENESIS; MIDAZOLAM; NEUROTOXICITY; PARAOXON; PESTICIDE; POISONING;

ANIMALS; ANTIDOTES; ATROPINE; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; CHRONIC DISEASE; EPILEPSY; MIDAZOLAM; MUSCARINIC AGONISTS; OBIDOXIME CHLORIDE; PARAOXON; PESTICIDES; PILOCARPINE; RATS; RATS, SPRAGUE-DAWLEY; STATUS EPILEPTICUS;

EID: 84902358173     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2014.05.010     Document Type: Article

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