Transcriptional upregulation of Cav3.2 mediates epileptogenesis in the pilocarpine model of epilepsy

Journal of Neuroscience

Volumn 28, Issue 49, 2008, Pages 13341-13353

  Becker, Albert J ^a   Pitsch, Julika ^a   Sochivko, Dmitry ^a   Opitz, Thoralf ^a   Staniek, Matthäus ^a,b   Chen, Chien Chang ^c   Campbell, Kevin P ^c   Schoch, Susanne ^a   Yaari, Yoel ^d   Beck, Heinz ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Burst discharge; Channelopathy; Epileptogenesis; Plasticity; Reorganization; Temporal lobe epilepsy

Indexed keywords

CALCIUM CHANNEL T TYPE; MESSENGER RNA; PILOCARPINE; VOLTAGE GATED CALCIUM CHANNEL; CA(V)3.2 PROTEIN, MOUSE; MUSCARINIC AGENT; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN NERVE CELL; CELL LOSS; CHRONIC DISEASE; CONTROLLED STUDY; DENDRITE; ELECTROENCEPHALOGRAPHY; EPILEPSY; EPILEPTIC STATE; EPILEPTOGENESIS; HIPPOCAMPUS; HUMAN; HUMAN CELL; MOSSY FIBER; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SEIZURE; UPREGULATION; ANIMAL; CALCIUM SIGNALING; CHANNELOPATHY; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; MALE; METABOLISM; MOUSE MUTANT; NERVE CELL; NERVE DEGENERATION; PATHOPHYSIOLOGY; TEMPORAL LOBE EPILEPSY; TRANSCRIPTION INITIATION; WISTAR RAT;

ANIMALS; CALCIUM CHANNELS, T-TYPE; CALCIUM SIGNALING; CHANNELOPATHIES; DISEASE MODELS, ANIMAL; EPILEPSY, TEMPORAL LOBE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HIPPOCAMPUS; MALE; MICE; MICE, KNOCKOUT; MOSSY FIBERS, HIPPOCAMPAL; MUSCARINIC AGONISTS; NERVE DEGENERATION; NEURONS; PILOCARPINE; PROTEIN SUBUNITS; RATS; RATS, WISTAR; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 58149395078     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1421-08.2008     Document Type: Article

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