Bio-derived poly(γ-Glutamic acid) nanogels as controlled anticancer drug delivery carriers

Journal of Microbiology and Biotechnology

Volumn 22, Issue 12, 2012, Pages 1782-1789

  Bae, Hee Ho ^a   Cho, Mi Young ^a   Hong, Ji Hyeon ^a   Poo, Haryoung ^b   Sung, Moon Hee ^c   Lim, Yong Taik ^a  

^a Chungnam National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Kookmin University   (South Korea)

Author keywords

Anticancer drugs; Drug delivery; Poly( glutamic acid); Polymer nanogel

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTINEOPLASTIC AGENT; DOXORUBICIN; GLUTATHIONE; MACROGOL; MERCAPTAMINE; POLY(GAMMA GLUTAMIC ACID); POLYMER; THIOL; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; BREAST CANCER; CANCER CELL; CONCENTRATION RESPONSE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; COVALENT BOND; CROSS LINKING; DISULFIDE BOND; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG DETERMINATION; DRUG EFFECT; DRUG SCREENING; DRUG SYNTHESIS; DRUG UPTAKE; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR TRANSPORT; NANOFABRICATION; PARTICLE SIZE; PROCESS DEVELOPMENT; SURFACE CHARGE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DISULFIDES; DOXORUBICIN; DRUG CARRIERS; GLUTATHIONE; HUMANS; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; POLYGLUTAMIC ACID;

BACILLI (CLASS);

EID: 84871123890     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.1208.08031     Document Type: Article

References (43)

1. Anderson, M. E. 1998. Glutathione: An overview of biosynthesis and modulation. Chem. Biol. Interact. 112: 1-14.
2. Bae, K. H., H. Mok, and T. G. Park. 2008. Synthesis, characterization, and intracellular delivery of reducible heparin nanogels for apoptotic cell death. Biomaterials 29: 3376-3383.
3. Bae, S. R., C. Park, J. C. Choi, H. Poo, C. J. Kim, and M. H. Sung. 2010. Effects of ultra high molecular weight polygamma- glutamic acid from Bacillus subtilis (Chungkookjang) on corneal wound healing. J. Microbiol. Biotechnol. 20: 803-808.
4. Bernkop-Schnurch, A. 2005. Thiomers: A new generation of mucoadhesive polymers. Adv. Drug Deliver. Rev. 57: 1569-1582.
5. Bravo-Osuna, I., D. Teutonico, S. Arpicco, C. Vauthier, and G. Ponchel. 2007. Characterization of chitosan thiolation and application to thiol quantification onto nanoparticle surface. Int. J. Pharm. 340: 173-181.
6. Cai, X. J., C. Y. Dong, H. Q. Dong, G. M. Wang, G. M. Pauletti, X. J. Pan, et al. 2012. Effective gene delivery using stimulus-responsive catiomer designed with redox-sensitive disulfide and acid-labile imine linkers. Biomacromolecules 13: 1024-1034.
7. Chang, D., J. Lei, H. R. Cui, N. Lu, Y. J. Sun, X. H. Zhang, C. Gao, H. Zheng, and Y. H. Yin. 2012. Disulfide cross-linked nanospheres from sodium alginate derivative for inflammatory bowel disease: Preparation, characterization, and in vitro drug release behavior. Carbohyd. Polym. 88: 663-669.
8. Chung, K. H., M. Y. Cho, M. H. Sung, H. Poo, and Y. T. Lim. 2011. Electrostatically assembled biocompatible polymer nanoparticles for MR/optical dual-modality imaging nanoprobes. Chem. Commun. 47: 8889-8891.
9. Chung, S. W., T. A. Hil-lal, and Y. Byun. 2012. Strategies for non-invasive delivery of biologics. J. Drug Target. 20: 481-501.
10. Ferrari, M. 2005. Cancer nanotechnology: Opportunities and challenges. Nat. Rev. Cancer 5: 161-171.
11. Hombach, J., T. F. Palmberger, and A. Bernkop-Schnurch. 2009. Development and in vitro evaluation of a mucoadhesive vaginal delivery system for nystatin. J. Pharm. Sci. 98: 555-564.
12. Kim, E., Y. Jung, H. Choi, J. Yang, J. S. Suh, Y. M. Huh, K. Kim, and S. Haam. 2010. Prostate cancer cell death produced by the co-delivery of Bcl-xL shRNA and doxorubicin using an aptamer-conjugated polyplex. Biomaterials 31: 4592-4599.
13. Kim, H. M., H. Lee, K. S. Hong, M. Y. Cho, M. H. Sung, H. Poo, and Y. T. Lim. 2011. Synthesis and high performance of magnetofluorescent polyelectrolyte nanocomposites as mr/nearinfrared multimodal cellular imaging nanoprobes. ACS Nano 5: 8230-8240.
14. Kommareddy, S. and M. Amiji. 2005. Preparation and evaluation of thiol-modified gelatin nanoparticles for intracellular DNA delivery in response to glutathione. Bioconjug. Chem. 16: 1423-1432.
15. Lee, D. E., H. Koo, I. C. Sun, J. H. Ryu, K. Kim, and I. C. Kwon. 2012. Multifunctional nanoparticles for multimodal imaging and theragnosis. Chem. Soc. Rev. 41: 2656-2672.
16. Lee, E. H., Y. Kamigaito, T. Tsujimoto, S. Seki, H. Uyama, S. Tagawa, and M. H. Sung. 2010. Preparation of poly(gammaglutamic acid) hydrogel/apatite composites and their application for scaffold of cell proliferation. Sen-I Gakkaishi 66: 104-111.
17. Lee, E. H., Y. Kamigaito, T. Tsujimoto, H. Uyama, and M. H. Sung. 2010. Synthesis of an amphiphilic poly(gamma-glutamic acid)-cholesterol conjugate and its application as an artificial chaperone. J. Microbiol. Biotechnol. 20: 1424-1429.
18. Lee, E. H., T. Tsujimoto, H. Uyama, M. H. Sung, K. Kim, and S. Kuramitsu. 2010. Enhancement of enzyme activity and stability by poly(gamma-glutamic acid). Polym. J. 42: 818-822.
19. Lee, E. H., H. Uyama, O. H. Kwon, and M. H. Sung. 2009. Fabrication of ultrafine fibers of poly(gamma-glutamic acid) and its derivative by electrospinning. Polym. Bull. 63: 735-742.
20. Lim, Y. T., Y. W. Noh, J. N. Kwon, and B. H. Chung. 2009. Multifunctional perfluorocarbon nanoemulsions for F-19-based magnetic resonance and near-infrared optical imaging of dendritic cells. Chem. Commun. 45: 6952-6954.
21. Lim, Y. T., S. M. Shim, Y. W. Noh, K. S. Lee, D. Y. Choi, H. Uyama, et al. 2011. Bioderived polyelectrolyte nanogels for robust antigen loading and vaccine adjuvant effects. Small 7: 3281-3286.
22. McClements, D. J. 2012. Crystals and crystallization in oil-inwater emulsions: Implications for emulsion-based delivery systems. Adv. Colloid. Interfac. 174: 1-30.
23. Mok, H., H. J. Kim, and T. G. Park. 2008. Dissolution of biomacromolecules in organic solvents by nano-complexing with poly(ethylene glycol). Int. J. Pharm. 356: 306-313.
24. Mok, H. and T. G. Park. 2006. PEG-assisted DNA solubilization in organic solvents for preparing cytosol specifically degradable PEG/DNA nanogels. Bioconjug. Chem. 17: 1369-1372.
25. Noh, Y. W., H. S. Park, M. H. Sung, and Y. T. Lim. 2011. Enhancement of the photostability and retention time of indocyanine green in sentinel lymph node mapping by anionic polyelectrolytes. Biomaterials 32: 6551-6557.
26. Oh, J. K., R. Drumright, D. J. Siegwart, and K. Matyjaszewski. 2008. The development of microgels/nanogels for drug delivery applications. Prog. Polym. Sci. 33: 448-477.
27. Park, H., J. Yang, J. Lee, S. Haam, I. H. Choi, and K. H. Yoo. 2009. Multifunctional nanoparticles for combined doxorubicin and photothermal treatments. ACS Nano 3: 2919-2926.
28. Park, H. S., J. E. Lee, M. Y. Cho, Y. W. Noh, M. H. Sung, H. Poo, K. S. Hong, and Y. T. Lim. 2011. pH-stimuli-responsive near-infrared optical imaging nanoprobe based on poly(gammaglutamic acid)/poly(beta-amino ester) nanoparticles. Nanotechnology 22: 465603.
29. Park, J. H., J. C. Choi, M. H. Sung, J. H. Kang, and M. J. Chang. 2011. High molecular weight poly-gamma-glutamic acid regulates lipid metabolism in rats fed a high-fat diet and humans. J. Microbiol. Biotechnol. 21: 766-775.
30. Park, K., S. Lee, E. Kang, K. Kim, K. Choi, and I. C. Kwon. 2009. New generation of multifunctional nanoparticles for cancer imaging and therapy. Adv. Funct. Mater. 19: 1553-1566.
31. Peppas, N. A., J. Z. Hilt, A. Khademhosseini, and R. Langer. 2006. Hydrogels in biology and medicine: From molecular principles to bionanotechnology. Adv. Mater. 18: 1345-1360.
32. Poo, H., H. M. Pyo, T. Y. Lee, S. W. Yoon, J. S. Lee, C. J. Kim, et al. 2006. Oral administration of human papillomavirus type 16 E7 displayed on Lactobacillus casei induces E7-specific antitumor effects in C57/BL6 mice. Int. J. Cancer 119: 1702-1709.
33. Sasaki, Y. and K. Akiyoshi. 2010. Nanogel engineering for new nanobiomaterials: from chaperoning engineering to biomedical applications. Chem. Rec. 10: 366-376.
34. Sasaki, Y. and K. Akiyoshi. 2012. Self-assembled nanogel engineering for advanced biomedical technology. Chem. Lett. 41: 202-208.
35. Seo, S. B., J. Yang, W. Hyung, E. J. Cho, T. I. Lee, Y. J. Song, et al. 2007. Novel multifunctional PHDCA/PEI nano-drug carriers for simultaneous magnetically targeted cancer therapy and diagnosis via magnetic resonance imaging. Nanotechnology 18: 475105.
36. Sweat, F. W. and W. W. Epstein. 1967. Dimethyl sulfoxide oxidations. J. Organic Chem. 32: 835-838.
37. Tsujimoto, T., J. Kimura, Y. Takeuchi, H. Uyama, C. Park, and M. H. Sung. 2010. Chelation of calcium ions by poly(gammaglutamic acid) from Bacillus subtilis (Chungkookjang). J. Microbiol. Biotechnol. 20: 1436-1439.
38. Verheul, R. J., S. van der Wal, and W. E. Hennink. 2010. Tailorable thiolated trimethyl chitosans for covalently stabilized nanoparticles. Biomacromolecules 11: 1965-1971.
39. Yang, J., J. Lee, J. Kang, K. Lee, J. S. Suh, H. G. Yoon, Y. M. Huh, and S. Haam. 2008. Hollow silica nanocontainers as drug delivery vehicles. Langmuir 24: 3417-3421.
40. Yoo, H. S. and T. G. Park. 2001. Biodegradable polymeric micelles composed of doxorubicin conjugated PLGA-PEG block copolymer. J. Control. Release 70: 63-70.
41. Yoo, H. S. and T. G. Park. 2004. Folate receptor targeted biodegradable polymeric doxorubicin micelles. J. Control. Release 96: 273-283.
42. Zhao, M. X., A. Biswas, B. L. Hu, K. I. Joo, P. Wang, Z. Gu, and Y. Tang. 2011. Redox-responsive nanocapsules for intracellular protein delivery. Biomaterials 32: 5223-5230.
43. Zhao, P. X. and D. Astruc. 2012. Docetaxel nanotechnology in anticancer therapy. Chem. Med. Chem. 7: 952-972.