메뉴 건너뛰기




Volumn 34, Issue 4, 2013, Pages 1364-1371

Biomineralization inspired surface engineering of nanocarriers for pH-responsive, targeted drug delivery

Author keywords

Biomineralization; Cancer therapy; Hyaluronic acid; Mesoporous nanomaterials; PH responsive; Targeted drug delivery

Indexed keywords

CANCER THERAPY; HYALURONIC ACIDS; MESOPOROUS; PH-RESPONSIVE; TARGETED DRUG DELIVERY;

EID: 84870353198     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.10.060     Document Type: Article
Times cited : (108)

References (52)
  • 1
    • 57349116196 scopus 로고    scopus 로고
    • Biomimetic systems for hydroxyapatite mineralization inspired by bone and enamel
    • Palmer L.C., Newcomb C.J., Kaltz S.R., Spoerke E.D., Stupp S.I. Biomimetic systems for hydroxyapatite mineralization inspired by bone and enamel. Chem Rev 2008, 108:4754-4783.
    • (2008) Chem Rev , vol.108 , pp. 4754-4783
    • Palmer, L.C.1    Newcomb, C.J.2    Kaltz, S.R.3    Spoerke, E.D.4    Stupp, S.I.5
  • 2
    • 49149091743 scopus 로고    scopus 로고
    • Calcium phosphate nanoparticles in biomineralization and biomaterials
    • Cai Y., Tang R. Calcium phosphate nanoparticles in biomineralization and biomaterials. J Mater Chem 2008, 18:3775-3787.
    • (2008) J Mater Chem , vol.18 , pp. 3775-3787
    • Cai, Y.1    Tang, R.2
  • 3
    • 54949132581 scopus 로고    scopus 로고
    • Bio-inspired, smart, multiscale interfacial materials
    • Xia F., Jiang L. Bio-inspired, smart, multiscale interfacial materials. Adv Mater 2008, 20:2842-2858.
    • (2008) Adv Mater , vol.20 , pp. 2842-2858
    • Xia, F.1    Jiang, L.2
  • 4
    • 81555195352 scopus 로고    scopus 로고
    • Biocatalytic nanoscale coatings through biomimetic layer-by-layer mineralization
    • Haase N.R., Shian S., Sandhage K.H., Kröger N. Biocatalytic nanoscale coatings through biomimetic layer-by-layer mineralization. Adv Funct Mater 2011, 21:4243-4251.
    • (2011) Adv Funct Mater , vol.21 , pp. 4243-4251
    • Haase, N.R.1    Shian, S.2    Sandhage, K.H.3    Kröger, N.4
  • 5
    • 0037028985 scopus 로고    scopus 로고
    • Bioinspired growth of crystalline carbonate apatite on biodegradable polymer substrata
    • Murphy W.L., Mooney D.J. Bioinspired growth of crystalline carbonate apatite on biodegradable polymer substrata. J Am Chem Soc 2002, 124:1910-1917.
    • (2002) J Am Chem Soc , vol.124 , pp. 1910-1917
    • Murphy, W.L.1    Mooney, D.J.2
  • 6
    • 80053308360 scopus 로고    scopus 로고
    • Multifunctional integration: from biological to bio-inspired materials
    • Liu K., Jiang L. Multifunctional integration: from biological to bio-inspired materials. ACS Nano 2011, 5:6786-6790.
    • (2011) ACS Nano , vol.5 , pp. 6786-6790
    • Liu, K.1    Jiang, L.2
  • 7
    • 84858198807 scopus 로고    scopus 로고
    • Preparation and characterization of 3D composite scaffolds based on rapid-prototyped PCL/β-TCP struts and electrospun PCL coated with collagen and ha for bone regeneration
    • Yeo M.G., Kim G.H. Preparation and characterization of 3D composite scaffolds based on rapid-prototyped PCL/β-TCP struts and electrospun PCL coated with collagen and ha for bone regeneration. Chem Mater 2011, 24:903-913.
    • (2011) Chem Mater , vol.24 , pp. 903-913
    • Yeo, M.G.1    Kim, G.H.2
  • 8
    • 0037018425 scopus 로고    scopus 로고
    • Liposome directed growth of calcium phosphate nanoshells
    • Schmidt H.T., Ostafin A.E. Liposome directed growth of calcium phosphate nanoshells. Adv Mater 2002, 14:532-535.
    • (2002) Adv Mater , vol.14 , pp. 532-535
    • Schmidt, H.T.1    Ostafin, A.E.2
  • 9
    • 9344236047 scopus 로고    scopus 로고
    • Assembly of aqueous-cored calcium phosphate nanoparticles for drug delivery
    • Schmidt H.T., Gray B.L., Wingert P.A., Ostafin A.E. Assembly of aqueous-cored calcium phosphate nanoparticles for drug delivery. Chem Mater 2004, 16:4942-4947.
    • (2004) Chem Mater , vol.16 , pp. 4942-4947
    • Schmidt, H.T.1    Gray, B.L.2    Wingert, P.A.3    Ostafin, A.E.4
  • 10
    • 78649390387 scopus 로고    scopus 로고
    • The role of collagen in bone apatite formation in the presence of hydroxyapatite nucleation inhibitors
    • Nudelman F., Pieterse K., George A., Bomans P.H.H., Friedrich H., Brylka L.J., et al. The role of collagen in bone apatite formation in the presence of hydroxyapatite nucleation inhibitors. Nat Mater 2010, 9:1004-1009.
    • (2010) Nat Mater , vol.9 , pp. 1004-1009
    • Nudelman, F.1    Pieterse, K.2    George, A.3    Bomans, P.H.H.4    Friedrich, H.5    Brylka, L.J.6
  • 12
    • 84863115632 scopus 로고    scopus 로고
    • Simultaneous reduction and surface functionalization of graphene oxide for hydroxyapatite mineralization
    • Liu H., Xi P., Xie G., Shi Y., Hou F., Huang L., et al. Simultaneous reduction and surface functionalization of graphene oxide for hydroxyapatite mineralization. J Phys Chem C 2012, 116:3334-3341.
    • (2012) J Phys Chem C , vol.116 , pp. 3334-3341
    • Liu, H.1    Xi, P.2    Xie, G.3    Shi, Y.4    Hou, F.5    Huang, L.6
  • 13
    • 57349168055 scopus 로고    scopus 로고
    • Calcium phosphate-based osteoinductive materials
    • LeGeros R.Z. Calcium phosphate-based osteoinductive materials. Chem Rev 2008, 108:4742-4753.
    • (2008) Chem Rev , vol.108 , pp. 4742-4753
    • LeGeros, R.Z.1
  • 14
    • 80051694467 scopus 로고    scopus 로고
    • Solid free-form fabrication of tissue-engineering scaffolds with a poly(lactic-co-glycolic acid) grafted hyaluronic acid conjugate encapsulating an intact bone morphogenetic protein-2/poly(ethylene glycol) complex
    • Park J.K., Shim J.-H., Kang K.S., Yeom J., Jung H.S., Kim J.Y., et al. Solid free-form fabrication of tissue-engineering scaffolds with a poly(lactic-co-glycolic acid) grafted hyaluronic acid conjugate encapsulating an intact bone morphogenetic protein-2/poly(ethylene glycol) complex. Adv Funct Mater 2011, 21:2906-2912.
    • (2011) Adv Funct Mater , vol.21 , pp. 2906-2912
    • Park, J.K.1    Shim, J.-H.2    Kang, K.S.3    Yeom, J.4    Jung, H.S.5    Kim, J.Y.6
  • 15
    • 61549092484 scopus 로고    scopus 로고
    • Mesenchymal stem cell proliferation and differentiation on an injectable calcium phosphate-chitosan composite scaffold
    • Moreau J.L., Xu H.H.K. Mesenchymal stem cell proliferation and differentiation on an injectable calcium phosphate-chitosan composite scaffold. Biomaterials 2009, 30:2675-2682.
    • (2009) Biomaterials , vol.30 , pp. 2675-2682
    • Moreau, J.L.1    Xu, H.H.K.2
  • 17
    • 79957438080 scopus 로고    scopus 로고
    • Mineralized hyaluronic acid nanoparticles as a robust drug carrier
    • Han S.-Y., Han H.S., Lee S.C., Kang Y.M., Kim I.-S., Park J.H. Mineralized hyaluronic acid nanoparticles as a robust drug carrier. J Mater Chem 2011, 21:7996-8001.
    • (2011) J Mater Chem , vol.21 , pp. 7996-8001
    • Han, S.-Y.1    Han, H.S.2    Lee, S.C.3    Kang, Y.M.4    Kim, I.-S.5    Park, J.H.6
  • 18
    • 32644483914 scopus 로고    scopus 로고
    • Effective transfection of cells with multi-shell calcium phosphate-DNA nanoparticles
    • Sokolova V.V., Radtke I., Heumann R., Epple M. Effective transfection of cells with multi-shell calcium phosphate-DNA nanoparticles. Biomaterials 2006, 27:3147-3153.
    • (2006) Biomaterials , vol.27 , pp. 3147-3153
    • Sokolova, V.V.1    Radtke, I.2    Heumann, R.3    Epple, M.4
  • 19
    • 82955164034 scopus 로고    scopus 로고
    • Freeze-dried cationic calcium phosphate nanorods as versatile carriers of nucleic acids (DNA, siRNA)
    • Klesing J., Chernousova S., Epple M. Freeze-dried cationic calcium phosphate nanorods as versatile carriers of nucleic acids (DNA, siRNA). J Mater Chem 2012, 22:199-204.
    • (2012) J Mater Chem , vol.22 , pp. 199-204
    • Klesing, J.1    Chernousova, S.2    Epple, M.3
  • 21
    • 61649093021 scopus 로고    scopus 로고
    • Calcium phosphate nanocomposite particles for in vitro imaging and encapsulated chemotherapeutic drug delivery to cancer cells
    • Kester M., Heakal Y., Fox T., Sharma A., Robertson G.P., Morgan T.T., et al. Calcium phosphate nanocomposite particles for in vitro imaging and encapsulated chemotherapeutic drug delivery to cancer cells. Nano Lett 2008, 8:4116-4121.
    • (2008) Nano Lett , vol.8 , pp. 4116-4121
    • Kester, M.1    Heakal, Y.2    Fox, T.3    Sharma, A.4    Robertson, G.P.5    Morgan, T.T.6
  • 22
    • 61649104326 scopus 로고    scopus 로고
    • Encapsulation of organic molecules in calcium phosphate nanocomposite particles for intracellular imaging and drug delivery
    • Morgan T.T., Muddana H.S., Altinoǧlu E.I., Rouse S.M., Tabaković A., Tabouillot T., et al. Encapsulation of organic molecules in calcium phosphate nanocomposite particles for intracellular imaging and drug delivery. Nano Lett 2008, 8:4108-4115.
    • (2008) Nano Lett , vol.8 , pp. 4108-4115
    • Morgan, T.T.1    Muddana, H.S.2    Altinoǧlu, E.I.3    Rouse, S.M.4    Tabaković, A.5    Tabouillot, T.6
  • 23
    • 79955096108 scopus 로고    scopus 로고
    • Ordered mesoporous polymer-silica hybrid nanoparticles as vehicles for the intracellular controlled release of macromolecules
    • Kim T.-W., Slowing I.I., Chung P.-W., Lin V.S.-Y. Ordered mesoporous polymer-silica hybrid nanoparticles as vehicles for the intracellular controlled release of macromolecules. ACS Nano 2010, 5:360-366.
    • (2010) ACS Nano , vol.5 , pp. 360-366
    • Kim, T.-W.1    Slowing, I.I.2    Chung, P.-W.3    Lin, V.S.-Y.4
  • 25
    • 78751529870 scopus 로고    scopus 로고
    • Polyvalent nucleic acid/mesoporous silica nanoparticle conjugates: dual stimuli-responsive vehicles for intracellular drug delivery
    • Chen C., Geng J., Pu F., Yang X., Ren J., Qu X. Polyvalent nucleic acid/mesoporous silica nanoparticle conjugates: dual stimuli-responsive vehicles for intracellular drug delivery. Angew Chem Int Ed 2011, 50:882-886.
    • (2011) Angew Chem Int Ed , vol.50 , pp. 882-886
    • Chen, C.1    Geng, J.2    Pu, F.3    Yang, X.4    Ren, J.5    Qu, X.6
  • 26
    • 70450177494 scopus 로고    scopus 로고
    • Enzyme responsive nanocontainers with cyclodextrin gatekeepers and synergistic effects in release of guests
    • Park C., Kim H., Kim S., Kim C. Enzyme responsive nanocontainers with cyclodextrin gatekeepers and synergistic effects in release of guests. J Am Chem Soc 2009, 131:16614-16615.
    • (2009) J Am Chem Soc , vol.131 , pp. 16614-16615
    • Park, C.1    Kim, H.2    Kim, S.3    Kim, C.4
  • 28
    • 84861809558 scopus 로고    scopus 로고
    • Near-infrared light-triggered, targeted drug delivery to cancer cells by aptamer gated nanovehicles
    • Yang X., Liu X., Liu Z., Pu F., Ren J., Qu X. Near-infrared light-triggered, targeted drug delivery to cancer cells by aptamer gated nanovehicles. Adv Mater 2012, 24:2890-2895.
    • (2012) Adv Mater , vol.24 , pp. 2890-2895
    • Yang, X.1    Liu, X.2    Liu, Z.3    Pu, F.4    Ren, J.5    Qu, X.6
  • 29
    • 0037461746 scopus 로고    scopus 로고
    • Photocontrolled reversible release of guest molecules from coumarin-modified mesoporous silica
    • Mal N.K., Fujiwara M., Tanaka Y. Photocontrolled reversible release of guest molecules from coumarin-modified mesoporous silica. Nature 2003, 421:350-353.
    • (2003) Nature , vol.421 , pp. 350-353
    • Mal, N.K.1    Fujiwara, M.2    Tanaka, Y.3
  • 30
    • 55549106158 scopus 로고    scopus 로고
    • Tunable redox-responsive hybrid nanogated ensembles
    • Liu R., Zhao X., Wu T., Feng P. Tunable redox-responsive hybrid nanogated ensembles. J Am Chem Soc 2008, 130:14418-14419.
    • (2008) J Am Chem Soc , vol.130 , pp. 14418-14419
    • Liu, R.1    Zhao, X.2    Wu, T.3    Feng, P.4
  • 31
    • 78651409823 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles end-capped with collagen: redox-responsive nanoreservoirs for targeted drug delivery
    • Luo Z., Cai K., Hu Y., Zhao L., Liu P., Duan L., et al. Mesoporous silica nanoparticles end-capped with collagen: redox-responsive nanoreservoirs for targeted drug delivery. Angew Chem Int Ed 2011, 50:640-643.
    • (2011) Angew Chem Int Ed , vol.50 , pp. 640-643
    • Luo, Z.1    Cai, K.2    Hu, Y.3    Zhao, L.4    Liu, P.5    Duan, L.6
  • 32
    • 79952342651 scopus 로고    scopus 로고
    • Stimuli-responsive controlled-release system using quadruplex DNA-capped silica nanocontainers
    • Chen C., Pu F., Huang Z., Liu Z., Ren J., Qu X. Stimuli-responsive controlled-release system using quadruplex DNA-capped silica nanocontainers. Nucleic Acids Res 2011, 39:1638-1644.
    • (2011) Nucleic Acids Res , vol.39 , pp. 1638-1644
    • Chen, C.1    Pu, F.2    Huang, Z.3    Liu, Z.4    Ren, J.5    Qu, X.6
  • 33
    • 84870347453 scopus 로고    scopus 로고
    • Cell-specific intracellular anticancer drug delivery from mesoporous silica nanoparticles with pH sensitivity
    • Luo Z., Cai K., Hu Y., Zhang B., Xu D. Cell-specific intracellular anticancer drug delivery from mesoporous silica nanoparticles with pH sensitivity. Adv Healthcare Mater 2012, 1:321-325.
    • (2012) Adv Healthcare Mater , vol.1 , pp. 321-325
    • Luo, Z.1    Cai, K.2    Hu, Y.3    Zhang, B.4    Xu, D.5
  • 34
    • 0041382648 scopus 로고    scopus 로고
    • Control of molecular transport through stimuli-responsive ordered mesoporous materials
    • Fu Q., Rao G.V.R., Ista L.K., Wu Y., Andrzejewski B.P., Sklar L.A., et al. Control of molecular transport through stimuli-responsive ordered mesoporous materials. Adv Mater 2003, 15:1262-1266.
    • (2003) Adv Mater , vol.15 , pp. 1262-1266
    • Fu, Q.1    Rao, G.V.R.2    Ista, L.K.3    Wu, Y.4    Andrzejewski, B.P.5    Sklar, L.A.6
  • 36
    • 80052590095 scopus 로고    scopus 로고
    • PH-tunable calcium phosphate covered mesoporous silica nanocontainers for intracellular controlled release of guest drugs
    • Rim H.P., Min K.H., Lee H.J., Jeong S.Y., Lee S.C. pH-tunable calcium phosphate covered mesoporous silica nanocontainers for intracellular controlled release of guest drugs. Angew Chem Int Ed 2011, 50:8853-8857.
    • (2011) Angew Chem Int Ed , vol.50 , pp. 8853-8857
    • Rim, H.P.1    Min, K.H.2    Lee, H.J.3    Jeong, S.Y.4    Lee, S.C.5
  • 37
    • 0037227965 scopus 로고    scopus 로고
    • CD44: from adhesion molecules to signalling regulators
    • Ponta H., Sherman L., Herrlich P.A. CD44: from adhesion molecules to signalling regulators. Nat Rev Mol Cell Biol 2003, 4:33-45.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 33-45
    • Ponta, H.1    Sherman, L.2    Herrlich, P.A.3
  • 38
    • 3042697038 scopus 로고    scopus 로고
    • Hyaluronan: from extracellular glue to pericellular cue
    • Toole B.P. Hyaluronan: from extracellular glue to pericellular cue. Nat Rev Cancer 2004, 4:528-539.
    • (2004) Nat Rev Cancer , vol.4 , pp. 528-539
    • Toole, B.P.1
  • 39
    • 79961097211 scopus 로고    scopus 로고
    • Characterization of CD44-mediated cancer cell uptake and intracellular distribution of hyaluronan-grafted liposomes
    • Qhattal H.S.S., Liu X. Characterization of CD44-mediated cancer cell uptake and intracellular distribution of hyaluronan-grafted liposomes. Mol Pharm 2011, 8:1233-1246.
    • (2011) Mol Pharm , vol.8 , pp. 1233-1246
    • Qhattal, H.S.S.1    Liu, X.2
  • 40
    • 0026446637 scopus 로고
    • CD44: the hyaluronan receptor
    • Underhill C. CD44: the hyaluronan receptor. J Cell Sci 1992, 103(Pt 2):293-298.
    • (1992) J Cell Sci , vol.103 , Issue.PART 2 , pp. 293-298
    • Underhill, C.1
  • 41
    • 0025282411 scopus 로고
    • CD44 is the principal cell surface receptor for hyaluronate
    • Aruffo A., Stamenkovic I., Melnick M., Underhill C.B., Seed B. CD44 is the principal cell surface receptor for hyaluronate. Cell 1990, 61:1303-1313.
    • (1990) Cell , vol.61 , pp. 1303-1313
    • Aruffo, A.1    Stamenkovic, I.2    Melnick, M.3    Underhill, C.B.4    Seed, B.5
  • 42
    • 51049098968 scopus 로고    scopus 로고
    • Anticancer therapeutics: targeting macromolecules and nanocarriers to hyaluronan or CD44, a hyaluronan receptor
    • Platt V.M., Szoka F.C. Anticancer therapeutics: targeting macromolecules and nanocarriers to hyaluronan or CD44, a hyaluronan receptor. Mol Pharm 2008, 5:474-486.
    • (2008) Mol Pharm , vol.5 , pp. 474-486
    • Platt, V.M.1    Szoka, F.C.2
  • 43
    • 0034208501 scopus 로고    scopus 로고
    • A hyaluronic acid-taxol antitumor bioconjugate targeted to cancer cells
    • Luo Y., Ziebell M.R., Prestwich G.D. A hyaluronic acid-taxol antitumor bioconjugate targeted to cancer cells. Biomacromolecules 2000, 1:208-218.
    • (2000) Biomacromolecules , vol.1 , pp. 208-218
    • Luo, Y.1    Ziebell, M.R.2    Prestwich, G.D.3
  • 44
    • 0028472794 scopus 로고
    • Functionalized derivatives of hyaluronic acid oligosaccharides: drug carriers and novel biomaterials
    • Pouyani T., Prestwich G.D. Functionalized derivatives of hyaluronic acid oligosaccharides: drug carriers and novel biomaterials. Bioconjug Chem 1994, 5:339-347.
    • (1994) Bioconjug Chem , vol.5 , pp. 339-347
    • Pouyani, T.1    Prestwich, G.D.2
  • 45
    • 84855455777 scopus 로고    scopus 로고
    • Sticky nanoparticles: a platform for siRNA delivery by a bis(zinc(ii) dipicolylamine)-functionalized, self-assembled nanoconjugate
    • Liu G., Choi K.Y., Bhirde A., Swierczewska M., Yin J., Lee S.W., et al. Sticky nanoparticles: a platform for siRNA delivery by a bis(zinc(ii) dipicolylamine)-functionalized, self-assembled nanoconjugate. Angew Chem Int Ed 2012, 51:445-449.
    • (2012) Angew Chem Int Ed , vol.51 , pp. 445-449
    • Liu, G.1    Choi, K.Y.2    Bhirde, A.3    Swierczewska, M.4    Yin, J.5    Lee, S.W.6
  • 46
    • 55749086601 scopus 로고    scopus 로고
    • Bioinspired surface immobilization of hyaluronic acid on monodisperse magnetite nanocrystals for targeted cancer imaging
    • Lee Y., Lee H., Kim Y.B., Kim J., Hyeon T., Park H., et al. Bioinspired surface immobilization of hyaluronic acid on monodisperse magnetite nanocrystals for targeted cancer imaging. Adv Mater 2008, 20:4154-4157.
    • (2008) Adv Mater , vol.20 , pp. 4154-4157
    • Lee, Y.1    Lee, H.2    Kim, Y.B.3    Kim, J.4    Hyeon, T.5    Park, H.6
  • 47
    • 67149136446 scopus 로고    scopus 로고
    • Self-assembled hyaluronic acid nanoparticles as a potential drug carrier for cancer therapy: synthesis, characterization, and in vivo biodistribution
    • Choi K.Y., Min K.H., Na J.H., Choi K., Kim K., Park J.H., et al. Self-assembled hyaluronic acid nanoparticles as a potential drug carrier for cancer therapy: synthesis, characterization, and in vivo biodistribution. J Mater Chem 2009, 19:4102-4107.
    • (2009) J Mater Chem , vol.19 , pp. 4102-4107
    • Choi, K.Y.1    Min, K.H.2    Na, J.H.3    Choi, K.4    Kim, K.5    Park, J.H.6
  • 48
    • 53149106578 scopus 로고    scopus 로고
    • Synthesis, characterization, and in vivo diagnostic applications of hyaluronic acid immobilized gold nanoprobes
    • Lee H., Lee K., Kim I.K., Park T.G. Synthesis, characterization, and in vivo diagnostic applications of hyaluronic acid immobilized gold nanoprobes. Biomaterials 2008, 29:4709-4718.
    • (2008) Biomaterials , vol.29 , pp. 4709-4718
    • Lee, H.1    Lee, K.2    Kim, I.K.3    Park, T.G.4
  • 49
    • 81855226471 scopus 로고    scopus 로고
    • Smart nanocarrier based on PEGylated hyaluronic acid for cancer therapy
    • Choi K.Y., Yoon H.Y., Kim J.-H., Bae S.M., Park R.-W., Kang Y.M., et al. Smart nanocarrier based on PEGylated hyaluronic acid for cancer therapy. ACS Nano 2011, 5:8591-8599.
    • (2011) ACS Nano , vol.5 , pp. 8591-8599
    • Choi, K.Y.1    Yoon, H.Y.2    Kim, J.-H.3    Bae, S.M.4    Park, R.-W.5    Kang, Y.M.6
  • 50
    • 4744355223 scopus 로고    scopus 로고
    • Hyaluronan catabolism: a new metabolic pathway
    • Stern R. Hyaluronan catabolism: a new metabolic pathway. Eur J Cell Biol 2004, 83:317-325.
    • (2004) Eur J Cell Biol , vol.83 , pp. 317-325
    • Stern, R.1
  • 51
    • 44749085645 scopus 로고    scopus 로고
    • Hyaluronidases in cancer biology
    • Robert S. Hyaluronidases in cancer biology. Semin Cancer Biol 2008, 18:275-280.
    • (2008) Semin Cancer Biol , vol.18 , pp. 275-280
    • Robert, S.1
  • 52


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.