Multifunctional and degradable zwitterionic nanogels for targeted delivery, enhanced MR imaging, reduction-sensitive drug release, and renal clearance

Biomaterials

Volumn 32, Issue 20, 2011, Pages 4604-4608

  Zhang, Lei ^a   Xue, Hong ^a   Cao, Zhiqiang ^a   Keefe, Andrew ^a   Wang, Jinnan ^b   Jiang, Shaoyi ^a  

^a University of Washington   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Degradable; MRI (magnetic resonance imaging); Reduction sensitive; Renal clearance; Targeting; Zwitterionic

Indexed keywords

DEGRADABLE; MRI (MAGNETIC RESONANCE IMAGING); RENAL CLEARANCE; TARGETING; ZWITTERIONIC;

COVALENT BONDS; DEGRADATION; ENCAPSULATION; ENDOTHELIAL CELLS; GLUCOSE; NANOPARTICLES; NANOSTRUCTURED MATERIALS; RESONANCE;

MAGNETIC RESONANCE IMAGING;

AMPHOLYTE; DEXTRAN; FERRIC OXIDE; NANOPARTICLE; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT;

ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG RELEASE; DRUG UPTAKE; GEL; HUMAN; HUMAN CELL; KIDNEY CLEARANCE; MACROPHAGE; NANOPHARMACEUTICS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELL LINE; DEXTRANS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENDOTHELIAL CELLS; GELS; HUMANS; KIDNEY; KIDNEY FUNCTION TESTS; MACROPHAGES; MAGNETIC RESONANCE IMAGING; MATERIALS TESTING; MICE; NANOPARTICLES;

EID: 79955524150     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.02.064     Document Type: Article

References (26)

1. McCarthy J.R., Kelly K.A., Sun E.Y., Weissleder R. Targeted delivery of multifunctional magnetic nanoparticles. Nanomedicine 2007, 2(2):153-167.
2. Sun C., Lee J.S.H., Zhang M.Q. Magnetic nanoparticles in MR imaging and drug delivery. Adv Drug Deliver Rev 2008, 60(11):1252-1265.
3. McCarthy J.R., Weissleder R. Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv Drug Deliver Rev 2008, 60(11):1241-1251.
4. Zhang L., Yu F.Q., Cole A.J., Chertok B., David A.E., Wang J.K., et al. Gum arabic-coated magnetic nanoparticles for potential application in simultaneous magnetic targeting and tumor imaging. AAPS J 2009, 11(4):693-699.
5. Horcajada P., Chalati T., Serre C., Gillet B., Sebrie C., Baati T., et al. Porous metal-organic-framework nanoscale carriers as a potential platform for drug delivery and imaging. Nat Mater 2010, 9(2):172-178.
6. Meng F.H., Hennink W.E., Zhong Z. Reduction-sensitive polymers and bioconjugates for biomedical applications. Biomaterials 2009, 30(12):2180-2198.
7. Oh J.K., Tang C.B., Gao H.F., Tsarevsky N.V., Matyjaszewski K. Inverse miniemulsion ATRP: a new method for synthesis and functionalization of well-defined water-soluble/cross-linked polymeric particles. J Am Chem Soc 2006, 128(16):5578-5584.
8. Jiang S.Y., Cao Z.Q. Ultralow-fouling, functionalizable, and hydrolyzable zwitterionic materials and their derivatives for biological applications. Adv Mater 2010, 22(9):920-932.
9. Jia G.W., Cao Z.Q., Xue H., Xu Y.S., Jiang S.Y. Novel zwitterionic-polymer-coated silica nanoparticles. Langmuir 2009, 25(5):3196-3199.
10. Yang W., Zhang L., Wang S.L., White A.D., Jiang S.Y. Functionalizable and ultra stable nanoparticles coated with zwitterionic poly(carboxybetaine) in undiluted blood serum. Biomaterials 2009, 30(29):5617-5621.
11. Zhang L., Xue H., Gao C.L., Carr L., Wang J.N., Chu B.C., et al. Imaging and cell targeting characteristics of magnetic nanoparticles modified by a functionalizable zwitterionic polymer with adhesive 3,4-dihydroxyphenyl-l-alanine linkages. Biomaterials 2010, 31(25):6582-6588.
12. Cao Z.Q., Yu Q.M., Xue H., Cheng G., Jiang S.Y. Nanoparticles for drug delivery prepared from amphiphilic plga zwitterionic block copolymers with sharp contrast in polarity between two blocks. Angew Chem Int Edit 2010, 49(22):3771-3776.
13. Cheng G., Mi L., Cao Z.Q., Xue H., Yu Q.M., Carr L., et al. Functionalizable and ultrastable zwitterionic nanogels. Langmuir 2010, 26(10):6883-6886.
14. Tanaka J., Stansbury J.W., Antonucci J.M., Suzuki K. Surface treatment with N, N'-Dimethacryloylcystine for enhanced bonding of resin to dental alloys. Dent Mater J 2007, 26(4):514-518.
15. Andrew B.G., Alexander Y.G., Toyoichi T. Shape imprinting due to variable disulfi{ligature}de bonds in polyacrylamide gels. J Chem Phys 2001, 114(23):10551-10556.
16. Emilitri E., Ranucci E., Ferruti P. New poly(amidoamine)s containing disulfide linkages in their main chain. J Polym Sci Pol Chem 2005, 43(7):1404-1416.
17. Park J., An K.J., Hwang Y.S., Park J.G., Noh H.J., Kim J.Y., et al. Ultra-large-scale syntheses of monodisperse nanocrystals. Nat Mater 2004, 3(12):891-895.
18. Liong M., Lu J., Kovochich M., Xia T., Ruehm S.G., Nel A.E., et al. Multifunctional inorganic nanoparticles for imaging, targeting, and drug delivery. ACS Nano 2008, 2(5):889-896.
19. Choi H.S., Liu W., Misra P., Tanaka E., Zimmer J.P., Ipe B.I., et al. Renal clearance of quantum dots. Nat Biotechnol 2007, 25(10):1165-1170.
20. Veiseh O., Gunn J.W., Zhang M.Q. Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging. Adv Drug Deliver Rev 2010, 62(3):284-304.
21. Xie J., Xu C., Kohler N., Hou Y., Sun S. Controlled PEGylation of monodisperse Fe3O4 nanoparticles for reduced non-specific uptake by macrophage cells. Adv Mater 2007, 19(20):3163-3166.
22. Fang C., Bhattarai N., Sun C., Zhang M.Q. Functionalized nanoparticles with long-term stability in biological media. Small 2009, 5(14):1637-1641.
23. Jun Y.W., Lee J.H., Cheon J. Chemical design of nanoparticle probes for high-performance magnetic resonance imaging. Angew Chem Int Ed 2008, 47(28):5122-5135.
24. Lee J.H., Jun Y.W., Yeon S.I., Shin J.S., Cheon J. Dual-mode nanoparticle probes for high-performance magnetic resonance and fluorescence imaging of neuroblastoma. Angew Chem Int Edit 2006, 45(48):8160-8162.
25. Reddy G.R., Bhojani M.S., McConville P., Moody J., Moffat B.A., Hall D.E., et al. Vascular targeted nanoparticles for imaging and treatment of brain tumors. Clin Cancer Res 2006, 12(22):6677-6686.
26. Moffat B.A., Reddy G.R., McConville P., Hall D.E., Chenevert T.L., Kopelman R.R., et al. A novel polyacrylamide magnetic nanoparticle contrast agent for molecular imaging using MRI. Mol Imaging 2003, 2(4):324-332.