A putative role of p53 pathway against impulse noise induced damage as demonstrated by protection with pifithrin-alpha and a Src inhibitor

Neuroscience Research

Volumn 81-82, Issue , 2014, Pages 30-37

  Fetoni, Anna R ^a   Bielefeld, Eric C ^b   Paludetti, Gaetano ^a   Nicotera, Thomas ^c   Henderson, Donald ^d  

^a CATHOLIC UNIVERSITY   (Italy)

^b OHIO STATE UNIVERSITY   (United States)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

^d UNIVERSITY AT BUFFALO   (United States)

Author keywords

Apoptosis; Noise; P53; Pifithrin alpha; Src inhibitor; Tyrosine kinase proteins

Indexed keywords

KX 1 004; KX1 004; PIFITHRIN ALPHA; PROTEIN P53; PROTEIN TYROSINE KINASE INHIBITOR; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; BENZOTHIAZOLE DERIVATIVE; INDOLE DERIVATIVE; KX1-004; PIFITHRIN; PROTEIN TYROSINE KINASE; TOLUENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CHINCHILLA; COCHLEA; COCHLEA INJURY; CONTROLLED STUDY; CORTI ORGAN; EAR PROTECTION; HAIR CELL; HEARING IMPAIRMENT; IMPULSE NOISE; INHIBITION KINETICS; NOISE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; AUDITORY THRESHOLD; DRUG EFFECTS; METABOLISM; NOISE INJURY;

ANIMALS; APOPTOSIS; AUDITORY THRESHOLD; BENZOTHIAZOLES; CHINCHILLA; COCHLEA; HEARING LOSS, NOISE-INDUCED; INDOLES; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TOLUENE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84902293478     PISSN: 01680102     EISSN: 18728111     Source Type: Journal    
DOI: 10.1016/j.neures.2014.01.006     Document Type: Article

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