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Volumn 462-463, Issue 1, 2014, Pages 14-24

Mapping of HPV transcripts in four human cervical lesions using RNAseq suggests quantitative rearrangements during carcinogenic progression

Author keywords

Carcinogenesis; HPV; Patient samples; Promoter usage; Quantification; RNAseq; Transcripts

Indexed keywords

APOLIPOPROTEIN E4; APOLIPOPROTEIN E5; GLYCOPROTEIN E1; GLYCOPROTEIN E2; PROTEIN E7; TRANSCRIPTOME;

EID: 84902289406     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2014.05.026     Document Type: Article
Times cited : (43)

References (51)
  • 1
    • 79960297210 scopus 로고    scopus 로고
    • Transcriptome sequencing demonstrates that human papillomavirus is not active in cutaneous squamous cell carcinoma
    • Arron S.T., Ruby J.G., Dybbro E., Ganem D., Derisi J.L. Transcriptome sequencing demonstrates that human papillomavirus is not active in cutaneous squamous cell carcinoma. J. Invest. Dermatol. 2011, 131:1745-1753.
    • (2011) J. Invest. Dermatol. , vol.131 , pp. 1745-1753
    • Arron, S.T.1    Ruby, J.G.2    Dybbro, E.3    Ganem, D.4    Derisi, J.L.5
  • 2
    • 80053557332 scopus 로고    scopus 로고
    • The human papillomavirus E6 oncogene represses a cell adhesion pathway and disrupts focal adhesion through degradation of TAp63beta upon transformation
    • Ben Khalifa Y., Teissier S., Tan M.K., Phan Q.T., Daynac M., et al. The human papillomavirus E6 oncogene represses a cell adhesion pathway and disrupts focal adhesion through degradation of TAp63beta upon transformation. PLoS Pathog. 2011, 7:e1002256.
    • (2011) PLoS Pathog. , vol.7
    • Ben Khalifa, Y.1    Teissier, S.2    Tan, M.K.3    Phan, Q.T.4    Daynac, M.5
  • 3
    • 0023144684 scopus 로고
    • Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines
    • Baker C.C., Phelps W.C., Lindgren V., Braun M.J., Gonda M.A., et al. Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines. J. Virol. 1987, 61:962-971.
    • (1987) J. Virol. , vol.61 , pp. 962-971
    • Baker, C.C.1    Phelps, W.C.2    Lindgren, V.3    Braun, M.J.4    Gonda, M.A.5
  • 4
    • 0025820471 scopus 로고
    • Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation
    • Bedell M.A., Hudson J.B., Golub T.R., Turyk M.E., Hosken M., et al. Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation. J. Virol. 1991, 65:2254-2260.
    • (1991) J. Virol. , vol.65 , pp. 2254-2260
    • Bedell, M.A.1    Hudson, J.B.2    Golub, T.R.3    Turyk, M.E.4    Hosken, M.5
  • 5
    • 84902279585 scopus 로고    scopus 로고
    • Maps of Papillomavirus mRNA Transcripts; Laboratory LAN. Los Alamos National Laboratory, NM.
    • Baker, C.C., Calef, C., 1996. Maps of Papillomavirus mRNA Transcripts; Laboratory LAN. Los Alamos National Laboratory, NM.
    • (1996)
    • Baker, C.C.1    Calef, C.2
  • 6
    • 77950938389 scopus 로고    scopus 로고
    • Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments
    • Bernard H.U., Burk R.D., Chen Z., van Doorslaer K., zur Hausen H., et al. Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments. Virology 2010, 401:70-79.
    • (2010) Virology , vol.401 , pp. 70-79
    • Bernard, H.U.1    Burk, R.D.2    Chen, Z.3    van Doorslaer, K.4    zur Hausen, H.5
  • 7
    • 0027358683 scopus 로고
    • The predominant mRNA class in HPV16-infected genital neoplasias does not encode the E6 or the E7 protein
    • Bohm S., Wilczynski S.P., Pfister H., Iftner T. The predominant mRNA class in HPV16-infected genital neoplasias does not encode the E6 or the E7 protein. Int. J. Cancer 1993, 55:791-798.
    • (1993) Int. J. Cancer , vol.55 , pp. 791-798
    • Bohm, S.1    Wilczynski, S.P.2    Pfister, H.3    Iftner, T.4
  • 8
    • 64749099749 scopus 로고    scopus 로고
    • Role of 5'- and 3'-untranslated regions of mRNAs in human diseases
    • Chatterjee S., Pal J.K. Role of 5'- and 3'-untranslated regions of mRNAs in human diseases. Biol. Cell 2009, 101:251-262.
    • (2009) Biol. Cell , vol.101 , pp. 251-262
    • Chatterjee, S.1    Pal, J.K.2
  • 9
    • 0023224637 scopus 로고
    • Human papillomavirus types 6 and 11 mRNAs from genital condylomata acuminata
    • Chow L.T., Nasseri M., Wolinsky S.M., Broker T.R. Human papillomavirus types 6 and 11 mRNAs from genital condylomata acuminata. J. Virol. 1987, 61:2581-2588.
    • (1987) J. Virol. , vol.61 , pp. 2581-2588
    • Chow, L.T.1    Nasseri, M.2    Wolinsky, S.M.3    Broker, T.R.4
  • 10
    • 0025148460 scopus 로고
    • Detection of novel splicing patterns in a HPV16-containing keratinocyte cell line
    • Doorbar J., Parton A., Hartley K., Banks L., Crook T., et al. Detection of novel splicing patterns in a HPV16-containing keratinocyte cell line. Virology 1990, 178:254-262.
    • (1990) Virology , vol.178 , pp. 254-262
    • Doorbar, J.1    Parton, A.2    Hartley, K.3    Banks, L.4    Crook, T.5
  • 11
    • 84866060807 scopus 로고    scopus 로고
    • Some novel insights on HPV16 related cervical cancer pathogenesis based on analyses of LCR methylation, viral load, E7 and E2/E4 expressions
    • Das Ghosh D., Bhattacharjee B., Sen S., Premi L., Mukhopadhyay I., et al. Some novel insights on HPV16 related cervical cancer pathogenesis based on analyses of LCR methylation, viral load, E7 and E2/E4 expressions. PLoS One 2012, 7:e44678.
    • (2012) PLoS One , vol.7
    • Das Ghosh, D.1    Bhattacharjee, B.2    Sen, S.3    Premi, L.4    Mukhopadhyay, I.5
  • 12
    • 14744285753 scopus 로고    scopus 로고
    • The papillomavirus life cycle
    • Doorbar J. The papillomavirus life cycle. J. Clin. Virol. 2005, 32(Suppl. 1):S7-S15.
    • (2005) J. Clin. Virol. , vol.32 , Issue.SUPPL. 1
    • Doorbar, J.1
  • 13
    • 0022671522 scopus 로고
    • Identification of the human papilloma virus-1a E4 gene products
    • Doorbar J., Campbell D., Grand R.J., Gallimore P.H. Identification of the human papilloma virus-1a E4 gene products. EMBO J. 1986, 5:355-362.
    • (1986) EMBO J. , vol.5 , pp. 355-362
    • Doorbar, J.1    Campbell, D.2    Grand, R.J.3    Gallimore, P.H.4
  • 14
    • 0033623193 scopus 로고    scopus 로고
    • The E1E4 protein of human papillomavirus type 16 associates with a putative RNA helicase through sequences in its C terminus
    • Doorbar J., Elston R.C., Napthine S., Raj K., Medcalf E., et al. The E1E4 protein of human papillomavirus type 16 associates with a putative RNA helicase through sequences in its C terminus. J. Virol. 2000, 74:10081-10095.
    • (2000) J. Virol. , vol.74 , pp. 10081-10095
    • Doorbar, J.1    Elston, R.C.2    Napthine, S.3    Raj, K.4    Medcalf, E.5
  • 15
    • 0028039853 scopus 로고
    • Human papillomavirus type 11 E2 proteins repress the homologous E6 promoter by interfering with the binding of host transcription factors to adjacent elements
    • Dong G., Broker T.R., Chow L.T. Human papillomavirus type 11 E2 proteins repress the homologous E6 promoter by interfering with the binding of host transcription factors to adjacent elements. J. Virol. 1994, 68:1115-1127.
    • (1994) J. Virol. , vol.68 , pp. 1115-1127
    • Dong, G.1    Broker, T.R.2    Chow, L.T.3
  • 16
    • 77952821748 scopus 로고    scopus 로고
    • In vitro progression of human papillomavirus 16 episome-associated cervical neoplasia displays fundamental similarities to integrant-associated carcinogenesis
    • Gray E., Pett M.R., Ward D., Winder D.M., Stanley M.A., et al. in vitro progression of human papillomavirus 16 episome-associated cervical neoplasia displays fundamental similarities to integrant-associated carcinogenesis. Cancer Res. 2010, 70:4081-4091.
    • (2010) Cancer Res. , vol.70 , pp. 4081-4091
    • Gray, E.1    Pett, M.R.2    Ward, D.3    Winder, D.M.4    Stanley, M.A.5
  • 17
    • 79960126958 scopus 로고    scopus 로고
    • FusionMap: detecting fusion genes from next-generation sequencing data at base-pair resolution
    • Ge H., Liu K., Juan T., Fang F., Newman M., et al. FusionMap: detecting fusion genes from next-generation sequencing data at base-pair resolution. Bioinformatics 2011, 27:1922-1928.
    • (2011) Bioinformatics , vol.27 , pp. 1922-1928
    • Ge, H.1    Liu, K.2    Juan, T.3    Fang, F.4    Newman, M.5
  • 18
    • 0029869006 scopus 로고    scopus 로고
    • Identification of a differenciation-inducible promoter in the E7 open reading frame of human papillomavirus type 16 (HPV16) in raft cultures of a new cell line containing high copy numbers of episomal HPV-16 DNA
    • Grassmann K., Rapp B., Maschek H., Petry K.U., Iftner T. Identification of a differenciation-inducible promoter in the E7 open reading frame of human papillomavirus type 16 (HPV16) in raft cultures of a new cell line containing high copy numbers of episomal HPV-16 DNA. J. Virol. 1996, 70:2339-2349.
    • (1996) J. Virol. , vol.70 , pp. 2339-2349
    • Grassmann, K.1    Rapp, B.2    Maschek, H.3    Petry, K.U.4    Iftner, T.5
  • 20
    • 84887373787 scopus 로고    scopus 로고
    • Methylation of human papillomavirus 16, 18, 31, and 45 L2 and L1 genes and the cellular DAPK gene: considerations for use as biomarkers of the progression of cervical neoplasia
    • Kalantari M., Osann K., Calleja-Macias I.E., Kim S., Yan B., et al. Methylation of human papillomavirus 16, 18, 31, and 45 L2 and L1 genes and the cellular DAPK gene: considerations for use as biomarkers of the progression of cervical neoplasia. Virology 2014, 448:314-321.
    • (2014) Virology , vol.448 , pp. 314-321
    • Kalantari, M.1    Osann, K.2    Calleja-Macias, I.E.3    Kim, S.4    Yan, B.5
  • 21
    • 84881229283 scopus 로고    scopus 로고
    • Landscape of DNA virus associations across human malignant cancers: analysis of 3,775 cases using RNA-Seq
    • Khoury J.D., Tannir N.M., Williams M.D., Chen Y., Yao H., et al. Landscape of DNA virus associations across human malignant cancers: analysis of 3,775 cases using RNA-Seq. J. Virol. 2013, 87:8916-8926.
    • (2013) J. Virol. , vol.87 , pp. 8916-8926
    • Khoury, J.D.1    Tannir, N.M.2    Williams, M.D.3    Chen, Y.4    Yao, H.5
  • 22
    • 84859210032 scopus 로고    scopus 로고
    • Fast gapped-read alignment with Bowtie 2
    • Langmead B., Salzberg S.L. Fast gapped-read alignment with Bowtie 2. Nat. Methods 2012, 9:357-359.
    • (2012) Nat. Methods , vol.9 , pp. 357-359
    • Langmead, B.1    Salzberg, S.L.2
  • 23
    • 84884574915 scopus 로고    scopus 로고
    • Localization of HPV-18 E2 at mitochondrial membranes induces ROS release and modulates host cell metabolism
    • Lai D., Tan C.L., Gunaratne J., Quek L.S., Nei W., et al. Localization of HPV-18 E2 at mitochondrial membranes induces ROS release and modulates host cell metabolism. PLoS One 2013, 8:e75625.
    • (2013) PLoS One , vol.8
    • Lai, D.1    Tan, C.L.2    Gunaratne, J.3    Quek, L.S.4    Nei, W.5
  • 24
    • 84881262448 scopus 로고    scopus 로고
    • Human papillomavirus type 58 genome variations and RNA expression in cervical lesions
    • Li Y., Wang X., Ni T., Wang F., Lu W., et al. Human papillomavirus type 58 genome variations and RNA expression in cervical lesions. J. Virol. 2013, 87:9313-9322.
    • (2013) J. Virol. , vol.87 , pp. 9313-9322
    • Li, Y.1    Wang, X.2    Ni, T.3    Wang, F.4    Lu, W.5
  • 25
    • 0036849734 scopus 로고    scopus 로고
    • Human papillomavirus immortalization and transformation functions
    • Munger K., Howley P.M. Human papillomavirus immortalization and transformation functions. Virus Res. 2002, 89:213-228.
    • (2002) Virus Res. , vol.89 , pp. 213-228
    • Munger, K.1    Howley, P.M.2
  • 26
    • 59549098296 scopus 로고    scopus 로고
    • The human papillomavirus E7 oncoprotein
    • McLaughlin-Drubin M.E., Munger K. The human papillomavirus E7 oncoprotein. Virology 2009, 384:335-344.
    • (2009) Virology , vol.384 , pp. 335-344
    • McLaughlin-Drubin, M.E.1    Munger, K.2
  • 27
    • 33847350903 scopus 로고    scopus 로고
    • Analysis of novel human papillomavirus type 16 late mRNAs in differentiated W12 cervical epithelial cells
    • Milligan S.G., Veerapraditsin T., Ahamet B., Mole S., Graham S.V. Analysis of novel human papillomavirus type 16 late mRNAs in differentiated W12 cervical epithelial cells. Virology 2007, 360:172-181.
    • (2007) Virology , vol.360 , pp. 172-181
    • Milligan, S.G.1    Veerapraditsin, T.2    Ahamet, B.3    Mole, S.4    Graham, S.V.5
  • 28
    • 70349739736 scopus 로고    scopus 로고
    • The Integrated Genome Browser: free software for distribution and exploration of genome-scale datasets
    • Nicol J.W., Helt G.A., Blanchard S.G., Raja A., Loraine A.E. The Integrated Genome Browser: free software for distribution and exploration of genome-scale datasets. Bioinformatics 2009, 25:2730-2731.
    • (2009) Bioinformatics , vol.25 , pp. 2730-2731
    • Nicol, J.W.1    Helt, G.A.2    Blanchard, S.G.3    Raja, A.4    Loraine, A.E.5
  • 29
    • 9044235579 scopus 로고    scopus 로고
    • Promoter usage in the E7 ORF of HPV16 correlates with epithelial differentiation and is largely confined to low-grade genital neoplasia
    • Nilsson C.H., Bakos E., Petry K.U., Schneider A., Durst M. Promoter usage in the E7 ORF of HPV16 correlates with epithelial differentiation and is largely confined to low-grade genital neoplasia. Int. J. Cancer 1996, 65:6-12.
    • (1996) Int. J. Cancer , vol.65 , pp. 6-12
    • Nilsson, C.H.1    Bakos, E.2    Petry, K.U.3    Schneider, A.4    Durst, M.5
  • 30
    • 0025311444 scopus 로고
    • Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters
    • Romanczuk H., Thierry F., Howley P.M. Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters. J. Virol. 1990, 64:2849-2859.
    • (1990) J. Virol. , vol.64 , pp. 2849-2859
    • Romanczuk, H.1    Thierry, F.2    Howley, P.M.3
  • 31
    • 0029939628 scopus 로고    scopus 로고
    • Characterization of human papillomavirus-11 mRNAs expressed in the context of autonomously replicating viral genomes
    • Renaud K.J., Cowsert L.M. Characterization of human papillomavirus-11 mRNAs expressed in the context of autonomously replicating viral genomes. Virology 1996, 220:177-185.
    • (1996) Virology , vol.220 , pp. 177-185
    • Renaud, K.J.1    Cowsert, L.M.2
  • 33
    • 0021986880 scopus 로고
    • Structure and transcription of human papillomavirus sequences in cervical carcinoma cells
    • Schwarz E., Freese U.K., Gissmann L., Mayer W., Roggenbuck B., et al. Structure and transcription of human papillomavirus sequences in cervical carcinoma cells. Nature 1985, 314:111-114.
    • (1985) Nature , vol.314 , pp. 111-114
    • Schwarz, E.1    Freese, U.K.2    Gissmann, L.3    Mayer, W.4    Roggenbuck, B.5
  • 34
    • 0023082241 scopus 로고
    • Identification of early proteins of the human papillomavirus type 16 (HPV16) and type 18 (HPV18) in cervical carcinoma cells
    • Seedorf K., Oltersdorf T., Krämmer G., Röwenkamp W. Identification of early proteins of the human papillomavirus type 16 (HPV16) and type 18 (HPV18) in cervical carcinoma cells. EMBO J. 1987, 6:139-144.
    • (1987) EMBO J. , vol.6 , pp. 139-144
    • Seedorf, K.1    Oltersdorf, T.2    Krämmer, G.3    Röwenkamp, W.4
  • 35
    • 0042552760 scopus 로고
    • Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein
    • Smotkin D., Wettstein F.O. Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein. Proc. Natl. Acad. Sci. USA 1986, 83:4680-4684.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 4680-4684
    • Smotkin, D.1    Wettstein, F.O.2
  • 37
    • 0024573764 scopus 로고
    • Oncogenic and nononcogenic human genital papillomaviruses generate the E7 mRNA by different mechanisms
    • Smotkin D., Prokoph H., Wettstein F.O. Oncogenic and nononcogenic human genital papillomaviruses generate the E7 mRNA by different mechanisms. J. Virol. 1989, 63:1441-1447.
    • (1989) J. Virol. , vol.63 , pp. 1441-1447
    • Smotkin, D.1    Prokoph, H.2    Wettstein, F.O.3
  • 38
    • 84866144195 scopus 로고    scopus 로고
    • Quantitative measurement of human papillomavirus type 16 e5 oncoprotein levels in epithelial cell lines by mass spectrometry
    • Sahab Z., Sudarshan S.R., Liu X., Zhang Y., Kirilyuk A., et al. Quantitative measurement of human papillomavirus type 16 e5 oncoprotein levels in epithelial cell lines by mass spectrometry. J. Virol. 2012, 86:9465-9473.
    • (2012) J. Virol. , vol.86 , pp. 9465-9473
    • Sahab, Z.1    Sudarshan, S.R.2    Liu, X.3    Zhang, Y.4    Kirilyuk, A.5
  • 39
    • 0026527588 scopus 로고
    • Expression and splicing patterns of human papillomavirus type-16 mRNAs in pre-cancerous lesions and carcinomas of the cervix, in human keratinocytes immortalized by HPV 16, and in cell lines established from cervical cancers
    • Sherman L., Alloul N., Golan I., Durst M., Baram A. Expression and splicing patterns of human papillomavirus type-16 mRNAs in pre-cancerous lesions and carcinomas of the cervix, in human keratinocytes immortalized by HPV 16, and in cell lines established from cervical cancers. Int. J. Cancer 1992, 50:356-364.
    • (1992) Int. J. Cancer , vol.50 , pp. 356-364
    • Sherman, L.1    Alloul, N.2    Golan, I.3    Durst, M.4    Baram, A.5
  • 40
    • 0026514428 scopus 로고
    • Human papillomavirus type 16 and 18 gene expression in cervical neoplasias
    • Stoler M.H., Rhodes C.R., Whitbeck A., Wolinsky S.M., Chow L.T., et al. Human papillomavirus type 16 and 18 gene expression in cervical neoplasias. Hum. Pathol. 1992, 23:117-128.
    • (1992) Hum. Pathol. , vol.23 , pp. 117-128
    • Stoler, M.H.1    Rhodes, C.R.2    Whitbeck, A.3    Wolinsky, S.M.4    Chow, L.T.5
  • 41
    • 0024422238 scopus 로고
    • Differentiation-linked human papillomavirus types 6 and 11 transcription in genital condylomata revealed by in situ hybridization with message-specific RNA probes
    • Stoler M.H., Wolinsky S.M., Whitbeck A., Broker T.R., Chow L.T. Differentiation-linked human papillomavirus types 6 and 11 transcription in genital condylomata revealed by in situ hybridization with message-specific RNA probes. Virology 1989, 172:331-340.
    • (1989) Virology , vol.172 , pp. 331-340
    • Stoler, M.H.1    Wolinsky, S.M.2    Whitbeck, A.3    Broker, T.R.4    Chow, L.T.5
  • 42
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: discovering splice junctions with RNA-Seq
    • Trapnell C., Pachter L., Salzberg S.L. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 2009, 25:1105-1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 43
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
    • Trapnell C., Williams B.A., Pertea G., Mortazavi A., Kwan G., et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat. Biotechnol. 2010, 28:511-515.
    • (2010) Nat. Biotechnol. , vol.28 , pp. 511-515
    • Trapnell, C.1    Williams, B.A.2    Pertea, G.3    Mortazavi, A.4    Kwan, G.5
  • 44
    • 59549085974 scopus 로고    scopus 로고
    • Transcriptional regulation of the papillomavirus oncogenes by cellular and viral transcription factors in cervical carcinoma
    • Thierry F. Transcriptional regulation of the papillomavirus oncogenes by cellular and viral transcription factors in cervical carcinoma. Virology 2009, 384:375-379.
    • (2009) Virology , vol.384 , pp. 375-379
    • Thierry, F.1
  • 45
    • 81055131727 scopus 로고    scopus 로고
    • Papillomavirus E5: the smallest oncoprotein with many functions
    • Venuti A., Paolini F., Nasir L., Corteggio A., Roperto S., et al. Papillomavirus E5: the smallest oncoprotein with many functions. Mol. Cancer 2011, 10:140.
    • (2011) Mol. Cancer , vol.10 , pp. 140
    • Venuti, A.1    Paolini, F.2    Nasir, L.3    Corteggio, A.4    Roperto, S.5
  • 46
    • 80052531865 scopus 로고    scopus 로고
    • Differential methylation of the HPV 16 upstream regulatory region during epithelial differentiation and neoplastic transformation
    • Vinokurova S., von Knebel Doeberitz M. Differential methylation of the HPV 16 upstream regulatory region during epithelial differentiation and neoplastic transformation. PLoS One 2011, 6:e24451.
    • (2011) PLoS One , vol.6
    • Vinokurova, S.1    von Knebel Doeberitz, M.2
  • 47
    • 0032840918 scopus 로고    scopus 로고
    • Human papillomavirus is a necessary cause of invasive cervical cancer worldwide
    • Walboomers J.M., Jacobs M.V., Manos M.M., Bosch F.X., Kummer J.A., et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J. Pathol. 1999, 189:12-19.
    • (1999) J. Pathol. , vol.189 , pp. 12-19
    • Walboomers, J.M.1    Jacobs, M.V.2    Manos, M.M.3    Bosch, F.X.4    Kummer, J.A.5
  • 48
    • 79961198210 scopus 로고    scopus 로고
    • Construction of a full transcription map of human papillomavirus type 18 during productive viral infection
    • Wang X., Meyers C., Wang H.K., Chow L.T., Zheng Z.M. Construction of a full transcription map of human papillomavirus type 18 during productive viral infection. J. Virol. 2011, 85:8080-8092.
    • (2011) J. Virol. , vol.85 , pp. 8080-8092
    • Wang, X.1    Meyers, C.2    Wang, H.K.3    Chow, L.T.4    Zheng, Z.M.5
  • 49
    • 77954365636 scopus 로고    scopus 로고
    • HPV16 E2 is an immediate early marker of viral infection, preceding E7 expression in precursor structures of cervical carcinoma
    • Xue Y., Bellanger S., Zhang W., Lim D., Low J., et al. HPV16 E2 is an immediate early marker of viral infection, preceding E7 expression in precursor structures of cervical carcinoma. Cancer Res. 2010, 70:5316-5325.
    • (2010) Cancer Res. , vol.70 , pp. 5316-5325
    • Xue, Y.1    Bellanger, S.2    Zhang, W.3    Lim, D.4    Low, J.5
  • 50
    • 85056027425 scopus 로고    scopus 로고
    • Loss of HPV16 E2 protein expression without disruption of the E2 ORF correlates with carcinogenic progression
    • Xue Y., Lim D., Zhi L., He P., Abastado J.P., et al. Loss of HPV16 E2 protein expression without disruption of the E2 ORF correlates with carcinogenic progression. Open Virol. J. 2012, 6:163-172.
    • (2012) Open Virol. J. , vol.6 , pp. 163-172
    • Xue, Y.1    Lim, D.2    Zhi, L.3    He, P.4    Abastado, J.P.5
  • 51
    • 33744756020 scopus 로고    scopus 로고
    • Papillomavirus genome structure, expression, and post-transcriptional regulation
    • Zheng Z.M., Baker C.C. Papillomavirus genome structure, expression, and post-transcriptional regulation. Front. Biosci. 2006, 11:2286-2302.
    • (2006) Front. Biosci. , vol.11 , pp. 2286-2302
    • Zheng, Z.M.1    Baker, C.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.