-
1
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander, E.S.; Linton, L.M.; Birren, B.; Nusbaum, C.; Zody, M.C.; Baldwin, J.; Devon, K.; Dewar, K.; Doyle, M.; FitzHugh, W.; et al. Initial sequencing and analysis of the human genome. Nature 2001, 409, 860-921.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
Devon, K.7
Dewar, K.8
Doyle, M.9
Fitzhugh, W.10
-
2
-
-
0002150481
-
Moderne probleme der humangenetik
-
Vogel, F. Moderne probleme der humangenetik. Ergeb. Inn. Med. Kinderheilkd 1959, 12, 52-125.
-
(1959)
Ergeb. Inn. Med. Kinderheilkd
, vol.12
, pp. 52-125
-
-
Vogel, F.1
-
3
-
-
0038497542
-
Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid
-
Watson, J.D.; Crick, F.H. Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid. Nature 1953, 171, 737-738.
-
(1953)
Nature
, vol.171
, pp. 737-738
-
-
Watson, J.D.1
Crick, F.H.2
-
4
-
-
79959503826
-
The international hapmap project
-
International HapMap Consortium
-
International HapMap Consortium. The international hapmap project. Nature 2003, 426, 789-796.
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
-
5
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff, L.A.; Sethupathy, P.; Junkins, H.A.; Ramos, E.M.; Mehta, J.P.; Collins, F.S.; Manolio, T.A. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc. Natl. Acad. Sci. USA 2009, 106, 9362-9367.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
Collins, F.S.6
Manolio, T.A.7
-
6
-
-
49949104757
-
Slco1b1 variants and statin-induced myopathy-A genomewide study
-
Link, E.; Parish, S.; Armitage, J.; Bowman, L.; Heath, S.; Matsuda, F.; Gut, I.; Lathrop, M.; Collins, R. Slco1b1 variants and statin-induced myopathy-A genomewide study. New Engl. J. Med. 2008, 359, 789-799.
-
(2008)
New Engl. J. Med
, vol.359
, pp. 789-799
-
-
Link, E.1
Parish, S.2
Armitage, J.3
Bowman, L.4
Heath, S.5
Matsuda, F.6
Gut, I.7
Lathrop, M.8
Collins, R.9
-
7
-
-
53449093633
-
Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome p450 cyp2c8 in multiple myeloma: A genome-wide single nucleotide polymorphism analysis
-
Sarasquete, M.E.; Garcia-Sanz, R.; Marin, L.; Alcoceba, M.; Chillon, M.C.; Balanzategui, A.; Santamaria, C.; Rosinol, L.; de la Rubia, J.; Hernandez, M.T.; et al. Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome p450 cyp2c8 in multiple myeloma: A genome-wide single nucleotide polymorphism analysis. Blood 2008, 112, 2709-2712.
-
(2008)
Blood
, vol.112
, pp. 2709-2712
-
-
Sarasquete, M.E.1
Garcia-Sanz, R.2
Marin, L.3
Alcoceba, M.4
Chillon, M.C.5
Balanzategui, A.6
Santamaria, C.7
Rosinol, L.8
de la Rubia, J.9
Hernandez, M.T.10
-
8
-
-
44049102035
-
Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis
-
Kindmark, A.; Jawaid, A.; Harbron, C.G.; Barratt, B.J.; Bengtsson, O.F.; Andersson, T.B.; Carlsson, S.; Cederbrant, K.E.; Gibson, N.J.; Armstrong, M.; et al. Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis. Pharmacogenomics J. 2008, 8, 186-195.
-
(2008)
Pharmacogenomics J
, vol.8
, pp. 186-195
-
-
Kindmark, A.1
Jawaid, A.2
Harbron, C.G.3
Barratt, B.J.4
Bengtsson, O.F.5
Andersson, T.B.6
Carlsson, S.7
Cederbrant, K.E.8
Gibson, N.J.9
Armstrong, M.10
-
9
-
-
67649859295
-
Hla-b*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin
-
Daly, A.K.; Donaldson, P.T.; Bhatnagar, P.; Shen, Y.; Pe'er, I.; Floratos, A.; Daly, M.J.; Goldstein, D.B.; John, S.; Nelson, M.R.;. Hla-b*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. Nat. Genet. 2009, 41, 816-819.
-
(2009)
Nat. Genet
, vol.41
, pp. 816-819
-
-
Daly, A.K.1
Donaldson, P.T.2
Bhatnagar, P.3
Shen, Y.4
Pe'er, I.5
Floratos, A.6
Daly, M.J.7
Goldstein, D.B.8
John, S.9
Nelson, M.R.10
-
10
-
-
79953197983
-
Hla-a*3101 and carbamazepine-induced hypersensitivity reactions in europeans
-
McCormack, M.; Alfirevic, A.; Bourgeois, S.; Farrell, J.J.; Kasperaviciute, D.; Carrington, M.; Sills, G.J.; Marson, T.; Jia, X.; de Bakker, P.I.; et al. Hla-a*3101 and carbamazepine-induced hypersensitivity reactions in europeans. New Engl. J. Med. 2011, 364, 1134-1143.
-
(2011)
New Engl. J. Med
, vol.364
, pp. 1134-1143
-
-
McCormack, M.1
Alfirevic, A.2
Bourgeois, S.3
Farrell, J.J.4
Kasperaviciute, D.5
Carrington, M.6
Sills, G.J.7
Marson, T.8
Jia, X.9
de Bakker, P.I.10
-
11
-
-
79551600984
-
Genome-wide association study identifies hla-a*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in japanese population
-
Ozeki, T.; Mushiroda, T.; Yowang, A.; Takahashi, A.; Kubo, M.; Shirakata, Y.; Ikezawa, Z.; Iijima, M.; Shiohara, T.; Hashimoto, K.; et al. Genome-wide association study identifies hla-a*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in japanese population. Hum. Mol. Gen. 2011, 20, 1034-1041.
-
(2011)
Hum. Mol. Gen
, vol.20
, pp. 1034-1041
-
-
Ozeki, T.1
Mushiroda, T.2
Yowang, A.3
Takahashi, A.4
Kubo, M.5
Shirakata, Y.6
Ikezawa, Z.7
Iijima, M.8
Shiohara, T.9
Hashimoto, K.10
-
12
-
-
84872905876
-
A whole-genome association study of major determinants for allopurinol-related stevens-johnson syndrome and toxic epidermal necrolysis in japanese patients
-
Tohkin, M.; Kaniwa, N.; Saito, Y.; Sugiyama, E.; Kurose, K.; Nishikawa, J.; Hasegawa, R.; Aihara, M.; Matsunaga, K.;Abe, M.; et al. A whole-genome association study of major determinants for allopurinol-related stevens-johnson syndrome and toxic epidermal necrolysis in japanese patients. Pharmacogenomics J. 2013, 13, 60-69.
-
(2013)
Pharmacogenomics J
, vol.13
, pp. 60-69
-
-
Tohkin, M.1
Kaniwa, N.2
Saito, Y.3
Sugiyama, E.4
Kurose, K.5
Nishikawa, J.6
Hasegawa, R.7
Aihara, M.8
Matsunaga, K.9
Abe, M.10
-
13
-
-
69249219296
-
Association of cytochrome p450 2c19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
-
Shuldiner, A.R.; O'Connell, J.R.; Bliden, K.P.; Gandhi, A.; Ryan, K.; Horenstein, R.B.; Damcott, C.M.; Pakyz, R.; Tantry, U.S.; Gibson Q.; et al. Association of cytochrome p450 2c19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. JAMA 2009, 302, 849-857.
-
(2009)
JAMA
, vol.302
, pp. 849-857
-
-
Shuldiner, A.R.1
O'Connell, J.R.2
Bliden, K.P.3
Gandhi, A.4
Ryan, K.5
Horenstein, R.B.6
Damcott, C.M.7
Pakyz, R.8
Tantry, U.S.9
Gibson, Q.10
-
14
-
-
70349292099
-
Genetic variation in il28b predicts hepatitis c treatment-induced viral clearance
-
Ge, D.; Fellay, J.; Thompson, A.J.; Simon, J.S.; Shianna, K.V.; Urban, T.J.; Heinzen, E.L.; Qiu, P.; Bertelsen, A.H.; Muir, A.J.; et al. Genetic variation in il28b predicts hepatitis c treatment-induced viral clearance. Nature 2009, 461, 399-401.
-
(2009)
Nature
, vol.461
, pp. 399-401
-
-
Ge, D.1
Fellay, J.2
Thompson, A.J.3
Simon, J.S.4
Shianna, K.V.5
Urban, T.J.6
Heinzen, E.L.7
Qiu, P.8
Bertelsen, A.H.9
Muir, A.J.10
-
15
-
-
63449117825
-
A genome-wide association study confirms vkorc1, cyp2c9, and cyp4f2 as principal genetic determinants of warfarin dose
-
Takeuchi, F.; McGinnis, R.; Bourgeois, S.; Barnes, C.; Eriksson, N.; Soranzo, N.; Whittaker, P.; Ranganath, V.; Kumanduri, V.; McLaren, W.; et al. A genome-wide association study confirms vkorc1, cyp2c9, and cyp4f2 as principal genetic determinants of warfarin dose. PLoS Genet. 2009, 5, e1000433.
-
(2009)
PLoS Genet
, vol.5
-
-
Takeuchi, F.1
McGinnis, R.2
Bourgeois, S.3
Barnes, C.4
Eriksson, N.5
Soranzo, N.6
Whittaker, P.7
Ranganath, V.8
Kumanduri, V.9
McLaren, W.10
-
16
-
-
84975742565
-
A map of human genome variation from population-scale sequencing
-
The 1000 Genomes Project Consortium
-
The 1000 Genomes Project Consortium. A map of human genome variation from population-scale sequencing. Nature 2010, 467, 1061-1073.
-
(2010)
Nature
, vol.467
, pp. 1061-1073
-
-
-
17
-
-
84897848726
-
Quantifying rare, deleterious variation in 12 human cytochrome p450 drug-metabolism genes in a large-scale exome dataset
-
Gordon, A.S.; Tabor, H.K.; Johnson, A.D.; Snively, B.M.; Assimes, T.L.; Auer, P.L.; Ioannidis, J.P.; Peters, U.; Robinson, J.G.; Sucheston, L.E.; et al. Quantifying rare, deleterious variation in 12 human cytochrome p450 drug-metabolism genes in a large-scale exome dataset. Hum. Mol. Gen. 2014. 23, 1957-1963.
-
(2014)
Hum. Mol. Gen
, vol.23
, pp. 1957-1963
-
-
Gordon, A.S.1
Tabor, H.K.2
Johnson, A.D.3
Snively, B.M.4
Assimes, T.L.5
Auer, P.L.6
Ioannidis, J.P.7
Peters, U.8
Robinson, J.G.9
Sucheston, L.E.10
-
18
-
-
59649117935
-
The largest prospective warfarin-treated cohort supports genetic forecasting
-
Wadelius, M.; Chen, L.Y.; Lindh, J.D.; Eriksson, N.; Ghori, M.J.; Bumpstead, S.; Holm, L.; McGinnis, R.; Rane, A.; Deloukas, P. The largest prospective warfarin-treated cohort supports genetic forecasting. Blood 2009, 113, 784-792.
-
(2009)
Blood
, vol.113
, pp. 784-792
-
-
Wadelius, M.1
Chen, L.Y.2
Lindh, J.D.3
Eriksson, N.4
Ghori, M.J.5
Bumpstead, S.6
Holm, L.7
McGinnis, R.8
Rane, A.9
Deloukas, P.10
-
19
-
-
43749083295
-
A vitamin k epoxide reductase complex subunit 1 mutation in an irish patient with warfarin resistance
-
Ainle, F.N.; Mumford, A.; Tallon, E.; McCarthy, D.; Murphy, K. A vitamin k epoxide reductase complex subunit 1 mutation in an irish patient with warfarin resistance. Irish J. Med. Sci. 2008, 177, 159-161.
-
(2008)
Irish J. Med. Sci
, vol.177
, pp. 159-161
-
-
Ainle, F.N.1
Mumford, A.2
Tallon, E.3
McCarthy, D.4
Murphy, K.5
-
20
-
-
52449098058
-
Pharmacodynamic resistance to warfarin is associated with nucleotide substitutions in vkorc1
-
Harrington, D.J.; Gorska, R.; Wheeler, R.; Davidson, S.; Murden, S.; Morse, C.; Shearer, M.J.; Mumford, A.D. Pharmacodynamic resistance to warfarin is associated with nucleotide substitutions in vkorc1. J. Thrombosis Haemost. 2008, 6, 1663-1670.
-
(2008)
J. Thrombosis Haemost
, vol.6
, pp. 1663-1670
-
-
Harrington, D.J.1
Gorska, R.2
Wheeler, R.3
Davidson, S.4
Murden, S.5
Morse, C.6
Shearer, M.J.7
Mumford, A.D.8
-
21
-
-
12344331747
-
Pharmacodynamic resistance to warfarin associated with a val66met substitution in vitamin k epoxide reductase complex subunit 1
-
Harrington, D.J.; Underwood, S.; Morse, C.; Shearer, M.J.; Tuddenham, E.G.; Mumford, A.D. Pharmacodynamic resistance to warfarin associated with a val66met substitution in vitamin k epoxide reductase complex subunit 1. Thromb. Haemost. 2005, 93, 23-26.
-
(2005)
Thromb. Haemost
, vol.93
, pp. 23-26
-
-
Harrington, D.J.1
Underwood, S.2
Morse, C.3
Shearer, M.J.4
Tuddenham, E.G.5
Mumford, A.D.6
-
22
-
-
10744228888
-
Mutations in vkorc1 cause warfarin resistance and multiple coagulation factor deficiency type 2
-
Rost, S.; Fregin, A.; Ivaskevicius, V.; Conzelmann, E.; Hortnagel, K.; Pelz, H.J.; Lappegard, K.; Seifried, E.; Scharrer, I.; Tuddenham, E.G.; Mutations in vkorc1 cause warfarin resistance and multiple coagulation factor deficiency type 2. Nature 2004, 427, 537-541.
-
(2004)
Nature
, vol.427
, pp. 537-541
-
-
Rost, S.1
Fregin, A.2
Ivaskevicius, V.3
Conzelmann, E.4
Hortnagel, K.5
Pelz, H.J.6
Lappegard, K.7
Seifried, E.8
Scharrer, I.9
Tuddenham, E.G.10
-
23
-
-
84872259284
-
Drug-induced arrhythmia: Pharmacogenomic prescribing
-
Behr, E.R.; Roden, D. Drug-induced arrhythmia: Pharmacogenomic prescribing? Eur. Heart J. 2013, 34, 89-95.
-
(2013)
Eur. Heart J
, vol.34
, pp. 89-95
-
-
Behr, E.R.1
Roden, D.2
-
24
-
-
84881170186
-
Novel rare variants in congenital cardiac arrhythmia genes are frequent in drug-induced torsades de pointes
-
Ramirez, A.H.; Shaffer, C.M.; Delaney, J.T.; Sexton, D.P.; Levy, S.E.; Rieder, M.J.; Nickerson, D.A.; George, A.L., Jr.; Roden, D.M. Novel rare variants in congenital cardiac arrhythmia genes are frequent in drug-induced torsades de pointes. Pharmacogenomics J. 2013, 13, 325-329.
-
(2013)
Pharmacogenomics J
, vol.13
, pp. 325-329
-
-
Ramirez, A.H.1
Shaffer, C.M.2
Delaney, J.T.3
Sexton, D.P.4
Levy, S.E.5
Rieder, M.J.6
Nickerson, D.A.7
George Jr., A.L.8
Roden, D.M.9
-
25
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
Consortium, E.P.; Bernstein, B.E.; Birney, E.; Dunham, I.; Green, E.D.; Gunter, C.; Snyder, M. An integrated encyclopedia of DNA elements in the human genome. Nature 2012, 489, 57-74.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Consortium, E.P.1
Bernstein, B.E.2
Birney, E.3
Dunham, I.4
Green, E.D.5
Gunter, C.6
Snyder, M.7
-
26
-
-
80055038826
-
Circulating micrornas as potential markers of human drug-induced liver injury
-
Starkey Lewis, P.J.; Dear, J.; Platt, V.; Simpson, K.J.; Craig, D.G.; Antoine, D.J.; French, N.S.; Dhaun, N.; Webb, D.J.; Costello, E.M.; et al. Circulating micrornas as potential markers of human drug-induced liver injury. Hepatology 2011, 54, 1767-1776.
-
(2011)
Hepatology
, vol.54
, pp. 1767-1776
-
-
Starkey Lewis, P.J.1
Dear, J.2
Platt, V.3
Simpson, K.J.4
Craig, D.G.5
Antoine, D.J.6
French, N.S.7
Dhaun, N.8
Webb, D.J.9
-
27
-
-
84895924095
-
Upregulation of mir-18a-5p contributes to epidermal necrolysis in severe drug eruptions
-
Ichihara, A.; Wang, Z.; Jinnin, M.; Izuno, Y.; Shimozono, N.; Yamane, K.; Fujisawa, A.; Moriya, C.; Fukushima, S.; Inoue, Y.; et al. Upregulation of mir-18a-5p contributes to epidermal necrolysis in severe drug eruptions. J. Allergy Clin. Immunol. 2013, 133, 1065-1074.
-
(2013)
J. Allergy Clin. Immunol
, vol.133
, pp. 1065-1074
-
-
Ichihara, A.1
Wang, Z.2
Jinnin, M.3
Izuno, Y.4
Shimozono, N.5
Yamane, K.6
Fujisawa, A.7
Moriya, C.8
Fukushima, S.9
-
28
-
-
78651394465
-
Bring on the biomarkers
-
Poste, G. Bring on the biomarkers. Nature 2011, 469, 156-157.
-
(2011)
Nature
, vol.469
, pp. 156-157
-
-
Poste, G.1
-
29
-
-
77954632352
-
-
Table of Pharmacogenomic Biomarkers in Drug Labeling. Available online, 6 November
-
US Food and Drug Administration. Table of Pharmacogenomic Biomarkers in Drug Labeling. Available online: http://www.fda.gov/drugs/scienceresearch/researchareas/pharmacogenetics/ ucm083378.htm/ (6 November 2013).
-
(2013)
US Food and Drug Administration
-
-
-
30
-
-
79951809825
-
Cpic: Clinical pharmacogenetics implementation consortium of the pharmacogenomics research network
-
Relling, M.V.; Klein, T.E. Cpic: Clinical pharmacogenetics implementation consortium of the pharmacogenomics research network. Clin. Pharmacol. Ther. 2011, 89, 464-467.
-
(2011)
Clin. Pharmacol. Ther
, vol.89
, pp. 464-467
-
-
Relling, M.V.1
Klein, T.E.2
-
31
-
-
79956306301
-
Phenotype standardization for immune-mediated drug-induced skin injury
-
Pirmohamed, M.; Friedmann, P.S.; Molokhia, M.; Loke, Y.K.; Smith, C.; Phillips, E.; La Grenade, L.; Carleton, B.; Papaluca-Amati, M.; Demoly, P.; et al. Phenotype standardization for immune-mediated drug-induced skin injury. Clin. Pharmacol. Ther. 2011, 89, 896-901.
-
(2011)
Clin. Pharmacol. Ther
, vol.89
, pp. 896-901
-
-
Pirmohamed, M.1
Friedmann, P.S.2
Molokhia, M.3
Loke, Y.K.4
Smith, C.5
Phillips, E.6
la Grenade, L.7
Carleton, B.8
Papaluca-Amati, M.9
-
32
-
-
79956333428
-
The phenotype standardization project: Improving pharmacogenetic studies of serious adverse drug reactions
-
Pirmohamed, M.; Aithal, G.P.; Behr, E.; Daly, A.; Roden, D. The phenotype standardization project: Improving pharmacogenetic studies of serious adverse drug reactions. Clin. Pharmacol. Ther. 2011, 89, 784-785.
-
(2011)
Clin. Pharmacol. Ther
, vol.89
, pp. 784-785
-
-
Pirmohamed, M.1
Aithal, G.P.2
Behr, E.3
Daly, A.4
Roden, D.5
-
33
-
-
84893484013
-
The international serious adverse events consortium (isaec) phenotype standardization project for drug-induced torsades de pointes
-
Behr, E.R.; January, C.; Schulze-Bahr, E.; Grace, A.A.; Kaab, S.; Fiszman, M.; Gathers, S.; Buckman, S.; Youssef, A.; Pirmohamed, M.;. The international serious adverse events consortium (isaec) phenotype standardization project for drug-induced torsades de pointes. Eur. Heart J. 2012. 34, 1958-1963
-
(2012)
Eur. Heart J
, vol.34
, pp. 1958-1963
-
-
Behr, E.R.1
January, C.2
Schulze-Bahr, E.3
Grace, A.A.4
Kaab, S.5
Fiszman, M.6
Gathers, S.7
Buckman, S.8
Youssef, A.9
Pirmohamed, M.10
-
34
-
-
0023850178
-
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase
-
Saiki, R.K.; Gelfand, D.H.; Stoffel, S.; Scharf, S.J.; Higuchi, R.; Horn, G.T.; Mullis, K.B.; Erlich, H.A. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 1988, 239, 487-491.
-
(1988)
Science
, vol.239
, pp. 487-491
-
-
Saiki, R.K.1
Gelfand, D.H.2
Stoffel, S.3
Scharf, S.J.4
Higuchi, R.5
Horn, G.T.6
Mullis, K.B.7
Erlich, H.A.8
-
35
-
-
84889873119
-
A randomized trial of genotype-guided dosing of warfarin
-
Pirmohamed, M.; Burnside, G.; Eriksson, N.; Jorgensen, A.L.; Toh, C.H.; Nicholson, T.; Kesteven, P.; Christersson, C.; Wahlstrom, B.; Stafberg, C.; et al. A randomized trial of genotype-guided dosing of warfarin. New Engl. J. Med. 2013, 369, 2294-2303.
-
(2013)
New Engl. J. Med
, vol.369
, pp. 2294-2303
-
-
Pirmohamed, M.1
Burnside, G.2
Eriksson, N.3
Jorgensen, A.L.4
Toh, C.H.5
Nicholson, T.6
Kesteven, P.7
Christersson, C.8
Wahlstrom, B.9
-
36
-
-
84860538806
-
Point-of-care genetic testing for personalisation of antiplatelet treatment (rapid gene): A prospective, randomised, proof-of-concept trial
-
Roberts, J.D.; Wells, G.A.; Le May, M.R.; Labinaz, M.; Glover, C.; Froeschl, M.; Dick, A.; Marquis, J.F.; O'Brien, E.; Goncalves, S.; et al. Point-of-care genetic testing for personalisation of antiplatelet treatment (rapid gene): A prospective, randomised, proof-of-concept trial. Lancet 2012, 379, 1705-1711.
-
(2012)
Lancet
, vol.379
, pp. 1705-1711
-
-
Roberts, J.D.1
Wells, G.A.2
Le May, M.R.3
Labinaz, M.4
Glover, C.5
Froeschl, M.6
Dick, A.7
Marquis, J.F.8
O'Brien, E.9
-
37
-
-
75149139045
-
Exciton primer-mediated snp detection in smartamp2 reactions
-
Lezhava, A.; Ishidao, T.; Ishizu, Y.; Naito, K.; Hanami, T.; Katayama, A.; Kogo, Y.; Soma, T.; Ikeda, S.; Murakami, K.; et al. Exciton primer-mediated snp detection in smartamp2 reactions. Hum. Mut. 2010, 31, 208-217.
-
(2010)
Hum. Mut
, vol.31
, pp. 208-217
-
-
Lezhava, A.1
Ishidao, T.2
Ishizu, Y.3
Naito, K.4
Hanami, T.5
Katayama, A.6
Kogo, Y.7
Soma, T.8
Ikeda, S.9
-
38
-
-
64149111606
-
Rapid single-nucleotide polymorphism detection of cytochrome p450 (cyp2c9) and vitamin k epoxide reductase (vkorc1) genes for the warfarin dose adjustment by the smart-amplification process version 2
-
Aomori, T.; Yamamoto, K.; Oguchi-Katayama, A.; Kawai, Y.; Ishidao, T.; Mitani, Y.; Kogo, Y.; Lezhava, A.; Fujita, Y.; Obayashi, K.; et al. Rapid single-nucleotide polymorphism detection of cytochrome p450 (cyp2c9) and vitamin k epoxide reductase (vkorc1) genes for the warfarin dose adjustment by the smart-amplification process version 2. Clin. Chem. 2009, 55, 804-812.
-
(2009)
Clin. Chem
, vol.55
, pp. 804-812
-
-
Aomori, T.1
Yamamoto, K.2
Oguchi-Katayama, A.3
Kawai, Y.4
Ishidao, T.5
Mitani, Y.6
Kogo, Y.7
Lezhava, A.8
Fujita, Y.9
-
39
-
-
84894355217
-
Company profile: Quantumdx group limited
-
Burn, J. Company profile: Quantumdx group limited. Pharmacogenomics 2013, 14, 1011-1015.
-
(2013)
Pharmacogenomics
, vol.14
, pp. 1011-1015
-
-
Burn, J.1
-
40
-
-
84858988492
-
Gene-z: A device for point of care genetic testing using a smartphone
-
Stedtfeld, R.D.; Tourlousse, D.M.; Seyrig, G.; Stedtfeld, T.M.; Kronlein, M.; Price, S.; Ahmad, F.; Gulari, E.; Tiedje, J.M.; Hashsham, S.A. Gene-z: A device for point of care genetic testing using a smartphone. Lab. Chip 2012, 12, 1454-1462.
-
(2012)
Lab. Chip
, vol.12
, pp. 1454-1462
-
-
Stedtfeld, R.D.1
Tourlousse, D.M.2
Seyrig, G.3
Stedtfeld, T.M.4
Kronlein, M.5
Price, S.6
Ahmad, F.7
Gulari, E.8
Tiedje, J.M.9
Hashsham, S.A.10
-
42
-
-
84888859773
-
Cyp2c19 genotype-based phase i studies of a c-met inhibitor tivantinib in combination with erlotinib, in advanced/metastatic non-small cell lung cancer
-
Yamamoto, N.; Murakami, H.; Hayashi, H.; Fujisaka, Y.; Hirashima, T.; Takeda, K.; Satouchi, M.; Miyoshi, K.; Akinaga, S.; Takahashi, T.; et al. Cyp2c19 genotype-based phase i studies of a c-met inhibitor tivantinib in combination with erlotinib, in advanced/metastatic non-small cell lung cancer. Br. J. Cancer 2013, 109, 2803-2809.
-
(2013)
Br. J. Cancer
, vol.109
, pp. 2803-2809
-
-
Yamamoto, N.1
Murakami, H.2
Hayashi, H.3
Fujisaka, Y.4
Hirashima, T.5
Takeda, K.6
Satouchi, M.7
Miyoshi, K.8
Akinaga, S.9
-
44
-
-
84862620703
-
Operational implementation of prospective genotyping for personalized medicine: The design of the vanderbilt predict project
-
Pulley, J.M.; Denny, J.C.; Peterson, J.F.; Bernard, G.R.; Vnencak-Jones, C.L.; Ramirez, A.H.; Delaney, J.T.; Bowton, E.; Brothers, K.; Johnson, K.; et al. Operational implementation of prospective genotyping for personalized medicine: The design of the vanderbilt predict project. Clin. Pharmacol. Ther. 2012, 92, 87-95.
-
(2012)
Clin. Pharmacol. Ther
, vol.92
, pp. 87-95
-
-
Pulley, J.M.1
Denny, J.C.2
Peterson, J.F.3
Bernard, G.R.4
Vnencak-Jones, C.L.5
Ramirez, A.H.6
Delaney, J.T.7
Bowton, E.8
Brothers, K.9
-
45
-
-
80053959309
-
Pharmacogenetics: Past, present and future
-
Pirmohamed, M. Pharmacogenetics: Past, present and future. Drug Discov. Today 2011, 16, 852-861.
-
(2011)
Drug Discov. Today
, vol.16
, pp. 852-861
-
-
Pirmohamed, M.1
-
46
-
-
0000793139
-
Cramming more components onto integrated circuits
-
Moore, G.E. Cramming more components onto integrated circuits. Electronics 1965, 38, 114-117.
-
(1965)
Electronics
, vol.38
, pp. 114-117
-
-
Moore, G.E.1
-
47
-
-
66249091930
-
The her-2 receptor and breast cancer: Ten years of targeted anti-her-2 therapy and personalized medicine
-
Ross, J.S.; Slodkowska, E.A.; Symmans, W.F.; Pusztai, L.; Ravdin, P.M.; Hortobagyi, G.N. The her-2 receptor and breast cancer: Ten years of targeted anti-her-2 therapy and personalized medicine. Oncologist 2009, 14, 320-368.
-
(2009)
Oncologist
, vol.14
, pp. 320-368
-
-
Ross, J.S.1
Slodkowska, E.A.2
Symmans, W.F.3
Pusztai, L.4
Ravdin, P.M.5
Hortobagyi, G.N.6
-
48
-
-
0035447953
-
Epidermal growth factor receptor immunohistochemical reactivity in patients with american joint committee on cancer stage iv colon adenocarcinoma: Implications for a standardized scoring system
-
Goldstein, N.S.; Armin, M. Epidermal growth factor receptor immunohistochemical reactivity in patients with american joint committee on cancer stage iv colon adenocarcinoma: Implications for a standardized scoring system. Cancer 2001, 92, 1331-1346.
-
(2001)
Cancer
, vol.92
, pp. 1331-1346
-
-
Goldstein, N.S.1
Armin, M.2
-
49
-
-
16544371910
-
Prevalence of kit expression in human tumors
-
Went, P.T.; Dirnhofer, S.; Bundi, M.; Mirlacher, M.; Schraml, P.; Mangialaio, S.; Dimitrijevic, S.; Kononen, J.; Lugli, A.; Simon, R.; et al. Prevalence of kit expression in human tumors. J. Clin. Oncol. 2004, 22, 4514-4522.
-
(2004)
J. Clin. Oncol
, vol.22
, pp. 4514-4522
-
-
Went, P.T.1
Dirnhofer, S.2
Bundi, M.3
Mirlacher, M.4
Schraml, P.5
Mangialaio, S.6
Dimitrijevic, S.7
Kononen, J.8
Lugli, A.9
-
50
-
-
59649127007
-
Eml4-alk rearrangement in non-small cell lung cancer and non-tumor lung tissues
-
Martelli, M.P.; Sozzi, G.; Hernandez, L.; Pettirossi, V.; Navarro, A.; Conte, D.; Gasparini, P.; Perrone, F.; Modena, P.; Pastorino, U.; et al. Eml4-alk rearrangement in non-small cell lung cancer and non-tumor lung tissues. Am. J. Pathol. 2009, 174, 661-670.
-
(2009)
Am. J. Pathol
, vol.174
, pp. 661-670
-
-
Martelli, M.P.1
Sozzi, G.2
Hernandez, L.3
Pettirossi, V.4
Navarro, A.5
Conte, D.6
Gasparini, P.7
Perrone, F.8
Modena, P.9
-
51
-
-
84874518093
-
Frequency and spectrum of braf mutations in a retrospective, single-institution study of 1112 cases of melanoma
-
Greaves, W.O.; Verma, S.; Patel, K.P.; Davies, M.A.; Barkoh, B.A.; Galbincea, J.M.; Yao, H.; Lazar, A.; Aldape, K.D.; Medeiros, L.J., et al. Frequency and spectrum of braf mutations in a retrospective, single-institution study of 1112 cases of melanoma. J. Mol. Diagn. 2012, 15, 220-226.
-
(2012)
J. Mol. Diagn
, vol.15
, pp. 220-226
-
-
Greaves, W.O.1
Verma, S.2
Patel, K.P.3
Davies, M.A.4
Barkoh, B.A.5
Galbincea, J.M.6
Yao, H.7
Lazar, A.8
Aldape, K.D.9
Medeiros, L.J.10
-
52
-
-
0038731306
-
K-ras oncogene mutations in sporadic colorectal cancer in the netherlands cohort study
-
Brink, M.; de Goeij, A.F.; Weijenberg, M.P.; Roemen, G.M.; Lentjes, M.H.; Pachen, M.M.; Smits, K.M.; de Bruine, A.P.; Goldbohm, R.A.; van den Brandt, P.A. K-ras oncogene mutations in sporadic colorectal cancer in the netherlands cohort study. Carcinogenesis 2003, 24, 703-710.
-
(2003)
Carcinogenesis
, vol.24
, pp. 703-710
-
-
Brink, M.1
de Goeij, A.F.2
Weijenberg, M.P.3
Roemen, G.M.4
Lentjes, M.H.5
Pachen, M.M.6
Smits, K.M.7
de Bruine, A.P.8
Goldbohm, R.A.9
van den Brandt, P.A.10
-
53
-
-
84885295208
-
Actionable, pathogenic incidental findings in 1,000 participants' exomes
-
Dorschner, M.O.; Amendola, L.M.; Turner, E.H.; Robertson, P.D.; Shirts, B.H.; Gallego, C.J.; Bennett, R.L.; Jones, K.L.; Tokita, M.J.; Bennett, J.T., et al. Actionable, pathogenic incidental findings in 1,000 participants' exomes. Am. J. Hum. Genet. 2013, 93, 631-640.
-
(2013)
Am. J. Hum. Genet
, vol.93
, pp. 631-640
-
-
Dorschner, M.O.1
Amendola, L.M.2
Turner, E.H.3
Robertson, P.D.4
Shirts, B.H.5
Gallego, C.J.6
Bennett, R.L.7
Jones, K.L.8
Tokita, M.J.9
Bennett, J.T.10
-
54
-
-
84880535720
-
Acmg recommendations for reporting of incidental findings in clinical exome and genome sequencing
-
Green, R.C.; Berg, J.S.; Grody, W.W.; Kalia, S.S.; Korf, B.R.; Martin, C.L.; McGuire, A.L.; Nussbaum, R.L.; O'Daniel, J.M.; Ormond, K.E., et al. Acmg recommendations for reporting of incidental findings in clinical exome and genome sequencing. Genet. Med. 2013, 15, 565-574.
-
(2013)
Genet. Med
, vol.15
, pp. 565-574
-
-
Green, R.C.1
Berg, J.S.2
Grody, W.W.3
Kalia, S.S.4
Korf, B.R.5
Martin, C.L.6
McGuire, A.L.7
Nussbaum, R.L.8
O'Daniel, J.M.9
Ormond, K.E.10
-
55
-
-
84896711144
-
Returning pleiotropic results from genetic testing to patients and research participants
-
Kocarnik, J.M.; Fullerton, S.M. Returning pleiotropic results from genetic testing to patients and research participants. JAMA 2014, 311, 795-796.
-
(2014)
JAMA
, vol.311
, pp. 795-796
-
-
Kocarnik, J.M.1
Fullerton, S.M.2
-
56
-
-
84898050496
-
Stakeholder views on pharmacogenomic testing
-
Patel, H.N.; Ursan, I.D.; Zueger, P.M.; Cavallari, L.H.; Pickard, A.S. Stakeholder views on pharmacogenomic testing. Pharmacotherapy 2014, 34, 151-165.
-
(2014)
Pharmacotherapy
, vol.34
, pp. 151-165
-
-
Patel, H.N.1
Ursan, I.D.2
Zueger, P.M.3
Cavallari, L.H.4
Pickard, A.S.5
-
57
-
-
84896525622
-
Similarities and differences in the oncology drug approval process between fda and european union with emphasis on in vitro companion diagnostics
-
Senderowicz, A.M.; Pfaff, O. Similarities and differences in the oncology drug approval process between fda and european union with emphasis on in vitro companion diagnostics. Clin. Cancer Res. 2014, 20, 1445-1452.
-
(2014)
Clin. Cancer Res
, vol.20
, pp. 1445-1452
-
-
Senderowicz, A.M.1
Pfaff, O.2
|