Quercetin-3-O- Glucoside induces human DNA topoisomerase II inhibition, cell cycle arrest and apoptosis in hepatocellular carcinoma cells

Anticancer Research

Volumn 34, Issue 4, 2014, Pages 1691-1700

  Sudan, Sudhanshu ^a   Rupasinghe, H P Vasantha ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Apoptosis; Cancer; Caspase 3; Cell cycle; HepG2 cells; Quercetin 3 O glucoside; Topoisomerase II

Indexed keywords

CASPASE 3; DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); ETOPOSIDE; ISOQUERCITRIN; LACTATE DEHYDROGENASE; SORAFENIB; ANTINEOPLASTIC AGENT; FLAVONOID; GYRASE INHIBITOR; QUERCETIN 3' O GLUCOSIDE; QUERCETIN 3'-O-GLUCOSIDE;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CAIMAN; CARCINOMA CELL; CELL CYCLE ARREST; CELL DEATH; CONTROLLED STUDY; DNA FRAGMENTATION ASSAY; DNA SUPERCOILING; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG SCREENING; ENZYME ASSAY; ENZYME INDUCTION; ENZYME INHIBITION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HEPG2 CELL LINE; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MALE; MTS ASSAY; NONHUMAN; PRIMARY CELL; PRIMARY CELL LINE; RAT; CELL CYCLE; CELL CYCLE CHECKPOINT; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECT; ENZYME ACTIVATION; HEPG2 CELLS; LIVER TUMOR; METABOLISM; NEOPLASM; QUERCETIN-3-O-GLUCOSIDE; TUMOR CELL LINE;

APOPTOSIS; CANCER; CASPASE-3; CELL CYCLE; HEPG2 CELLS; QUERCETIN-3-O-GLUCOSIDE; TOPOISOMERASE II;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DNA TOPOISOMERASES, TYPE II; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FLAVONOIDS; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; TOPOISOMERASE II INHIBITORS;

EID: 84902271842     PISSN: 02507005     EISSN: 17917530     Source Type: Journal    
DOI: None     Document Type: Article

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