SSP-002392, a new 5-HT4 receptor agonist, dose-dependently reverses scopolamine-induced learning and memory impairments in C57Bl/6 mice

Neuropharmacology

Volumn 85, Issue , 2014, Pages 178-189

  Lo, Adrian C ^a,b   De Maeyer, Joris H ^c   Vermaercke, Ben ^a,b   Callaerts Vegh, Zsuzsanna ^a,b   Schuurkes, Jan A J ^c   D'Hooge, Rudi ^a,b  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b Leuven Research Institute for Neuroscience and Disease O and N4   (Belgium)

^c Movetis NV   (Belgium)

Author keywords

Cognition; Morris water maze; Passive avoidance; Search strategies; SSP 002392

Indexed keywords

GALANTAMINE; SEROTONIN 4 AGONIST; SSP 002392; UNCLASSIFIED DRUG; 4-AMINO-5-CHLORO-2,3-DIHYDROBENZOFURAN-7-CARBOXYLIC ACID (3-HYDROXY-1-(3-METHOXYPROPYL)PIPERIDIN-4YLMETHYL)AMIDE; BENZOFURAN DERIVATIVE; NOOTROPIC AGENT; PIPERIDINE DERIVATIVE; SCOPOLAMINE BROMIDE; SEROTONIN 4 RECEPTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; LEARNING DISORDER; LONG TERM MEMORY; MALE; MAZE TEST; MEMORY CONSOLIDATION; MEMORY DISORDER; MORRIS WATER MAZE; MOUSE; NEUROPROTECTION; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; SPATIAL LEARNING; TASK PERFORMANCE; ANIMAL; ANXIETY; AVOIDANCE BEHAVIOR; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; FEAR; MEMORY DISORDERS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZATION;

ANIMALS; ANXIETY; AVOIDANCE LEARNING; BENZOFURANS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEAR; GALANTAMINE; MALE; MAZE LEARNING; MEMORY DISORDERS; MICE, INBRED C57BL; NOOTROPIC AGENTS; PIPERIDINES; RANDOM ALLOCATION; RECEPTORS, SEROTONIN, 5-HT4; SCOPOLAMINE HYDROBROMIDE; SEROTONIN 5-HT4 RECEPTOR AGONISTS;

EID: 84902263151     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.05.013     Document Type: Article

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