Biophysical characterization of sites of host adaptive mutation in the influenza A virus RNA polymerase PB2 RNA-binding domain

International Journal of Biochemistry and Cell Biology

Volumn 53, Issue , 2014, Pages 237-245

  Lim, Kyungeun ^a   Kim, Meehyein ^b   Lee, Mi Kyung ^a   Ko, Junsang ^a   Hong, Sungwoo ^a   Choi, Byong Seok ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

Host adaptive mutation; Influenza RNA polymerase; Nuclear magnetic resonance; PB2 subunit; RNA binding activity

Indexed keywords

LUCIFERASE; RNA POLYMERASE; RNA POLYMERASE PB2; UNCLASSIFIED DRUG; VIRUS ENZYME; PB2 PROTEIN, INFLUENZAVIRUS A; RNA; RNA BINDING PROTEIN; RNA DIRECTED RNA POLYMERASE; VIRUS PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE MUTATION; HOST PATHOGEN INTERACTION; INFLUENZA VIRUS A; LUCIFERASE ASSAY; MUTAGENESIS; NONHUMAN; PROTEIN DOMAIN; PROTEIN RNA BINDING; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BIOPHYSICS; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MUTATION; PATHOGENICITY; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BIOPHYSICAL PHENOMENA; HUMANS; INFLUENZA A VIRUS; MUTAGENESIS; MUTATION; PROTEIN STRUCTURE, TERTIARY; RNA; RNA REPLICASE; RNA-BINDING PROTEINS; VIRAL PROTEINS;

EID: 84902212080     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2014.05.022     Document Type: Article

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