Rabies virus envelope glycoprotein targets lentiviral vectors to the axonal retrograde pathway in motor neurons

Journal of Biological Chemistry

Volumn 289, Issue 23, 2014, Pages 16148-16163

  Hislop, James N ^a,d   Islam, Tarin A ^a   Eleftheriadou, Ioanna ^a   Carpentier, David C J ^a,e   Trabalza, Antonio ^a   Parkinson, Michael ^b   Schiavo, Giampietro ^b,c   Mazarakis, Nicholas D ^a  

^a Gene Therapy Centre for Neuroinflammation and Neurodegeneration Division of Brain Sciences Department of Medicine   (United Kingdom)

^b THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF ABERDEEN   (United Kingdom)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOPHAGES; BIOLOGICAL MEMBRANES; BRAIN; GENE THERAPY; MOLECULAR BIOLOGY; PROTEINS; VECTORS;

ENVELOPE GLYCOPROTEINS; LABELING TECHNIQUES; LENTIVIRAL VECTOR; MOLECULAR PROCESS; NEURAL CELL ADHESION MOLECULES; NICOTINIC ACETYLCHOLINE RECEPTORS; P75 NEUROTROPHIN RECEPTOR; TRANSDUCTION EFFICIENCY;

NEURONS;

LENTIVIRUS VECTOR; NERVE CELL ADHESION MOLECULE; NEUROTOXIN; NEUROTROPHIN RECEPTOR P75; NICOTINIC RECEPTOR; RABIES VIRUS ENVELOPE GLYCOPROTEIN; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CELL COMPARTMENTALIZATION; CHEMICAL LABELING; EMBRYO; ENDOCYTOSIS; ENDOSOME; FEMALE; FLUORESCENCE; INTERNALIZATION; MOTONEURON; MOUSE; NERVE CELL CULTURE; NONHUMAN; PH; PRIORITY JOURNAL; PSEUDOTYPING; RABIES VIRUS; RAT; RETROGRADE NERVE FIBER TRANSPORT; TETANUS; VIRAL GENE DELIVERY SYSTEM;

AXON; ENDOSOME; GLYCOPROTEIN; LENTIVIRUS; RAB PROTEINS; TRAFFICKING;

ANIMALS; AXONAL TRANSPORT; ENDOCYTOSIS; GENETIC VECTORS; HEK293 CELLS; HUMANS; LENTIVIRUS; MOTOR NEURONS; RABIES VIRUS; RATS; VIRAL ENVELOPE PROTEINS;

EID: 84902197218     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.549980     Document Type: Article

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