Visualization of DC-SIGN-Mediated Entry Pathway of Engineered Lentiviral Vectors in Target Cells

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Liu, Yarong ^a   Tai, April ^a   Joo, Kye Il ^a   Wang, Pin ^a,b  

^a University of Southern California ^*  (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD209 ANTIGEN; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; VPR PROTEIN;

ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DENDRITIC CELL; ENDOCYTOSIS; ENDOSOME; INTRACELLULAR TRANSPORT; MICROTUBULE; MUTANT; NONHUMAN; PH; TARGET CELL; VIRAL GENE DELIVERY SYSTEM; VIRUS ENTRY; VIRUS INFECTIVITY; VIRUS PARTICLE;

AUTOPHAGY; CELL ADHESION MOLECULES; CLATHRIN; DENDRITIC CELLS; ENDOCYTOSIS; ENDOSOMES; GENETIC ENGINEERING; GENETIC VECTORS; HEK293 CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; HYDROGEN-ION CONCENTRATION; LECTINS, C-TYPE; LENTIVIRUS; LYSOSOMES; MICROSCOPY, CONFOCAL; MICROTUBULES; RECEPTORS, CELL SURFACE; SINGLE-CELL ANALYSIS; TRANSDUCTION, GENETIC; VIRUS INTERNALIZATION;

SINDBIS VIRUS;

EID: 84879538190     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067400     Document Type: Article

References (63)

1. Banchereau J, Steinman RM, (1998) Dendritic cells and the control of immunity. Nature 392: 245-252.
2. Geijtenbeek TB, Kwon DS, Torensma R, van Vliet SJ, van Duijnhoven GC, et al. (2000) DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell 100: 587-597.
3. Geijtenbeek TB, Torensma R, van Vliet SJ, van Duijnhoven GC, Adema GJ, et al. (2000) Identification of DC-SIGN, a novel dendritic cell- specific ICAM-3 receptor that supports primary immune responses. Cell 100: 575-585.
4. Mellman I, Steinman RM, (2001) Dendritic cells: specialized and regulated antigen processing machines. Cell 106: 255-258.
5. Berzofsky JA, Ahlers JD, Belyakov IM, (2001) Strategies for designing and optimizing new generation vaccines. Nature Reviews Immunology 1: 209-219.
6. Timmerman JM, Levy R, (1999) Dendritic cell vaccines for cancer immunotherapy. Annu Rev Med 50: 507-529.
7. Breckpot K, Heirman C, Neyns B, Thielemans K, (2004) Exploiting dendritic cells for cancer immunotherapy: genetic modification of dendritic cells. J Gene Med 6: 1175-1188.
8. Kirk CJ, Mulé JJ, (2000) Gene-modified dendritic cells for use in tumor vaccines Human Gene Ther. 11: 797-806.
9. Bukrinsky MI, Sharova N, Dempsey MP, Stanwick TL, Bukrinskaya AG, et al. (1992) Active nuclear import of human immunodeficiency virus type 1 preintegration complexes. Proc Natl Acad Sci U S A 89: 6580-6584.
10. Lewis P, Hensel M, Emerman M, (1992) Human immunodeficiency virus infection of cells arrested in the cell cycle. EMBO J 11: 3053-3058.
11. Weinberg JB, Matthews TJ, Cullen BR, Malim MH, (1991) Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes. J Exp Med 174: 1477-1482.
12. Cronin J, Zhang XY, Reiser J, (2005) Altering the tropism of lentiviral vectors through pseudotyping. Curr Gene Ther 5: 387-398.
13. Waehler R, Russell SJ, Curiel D, (2007) Engineering targeted viral vectors for gene therapy. Nat Rev Genet 8: 573-587.
14. Yang L, Yang H, Rideout K, Cho T, Joo KI, et al. (2008) Engineered lentivector targeting of dendritic cells for in vivo immunization. Nat Biotechnol 26: 326-334.
15. Anderson JL, Hope TJ, (2005) Intracellular trafficking of retroviral vectors: obstacles and advances. Gene Ther 12: 1667-1678.
16. Gruenberg J, (2001) The endocytic pathway: a mosaic of domains. Nat Rev Mol Cell Biol 2: 721-730.
17. Klasse PJ, Bron R, Marsh M, (1988) Mechanisms of enveloped virus entry into animal cells. Adv Drug Deliv Rev 34: 65-91.
18. Martin K, Helenius A, (1991) Transport of incoming influenza virus nucleocapsids into the nucleus. J Virol 65: 232-244.
19. Joo KI, Wang P, (2008) Visualization of targeted transduction by engineered lentiviral vectors. Gene Ther 15: 1384-1396.
20. Mountain A, (2000) Gene therapy: the first decade. Trends Biotechnol 18: 119-128.
21. Rink J, Ghigo E, Kalaidzidis Y, Zerial M, (2005) Rab conversion as a mechanism of progression from early to late endosomes. Cell 122: 735-749.
22. Stoorvogel W, Strous GJ, Geuze HJ, Oorschot V, Schwartz AL, (1991) Late endosomes derive from early endosomes by maturation. Cell 65: 417-427.
23. Van der Bliek AM, Redelmeier T, Damke H, Schmid SL, Meyerowitz EM, et al. (1993) Mutations in human dynamin block an intermediate stage in coated vesicle formation. J Cell Biol 122: 553-563.
24. Joo KI, Tai A, Lee CL, Wong C, Wang P, (2010) Imaging multiple intermediates of single-virus membrane fusion mediated by distinct fusion proteins. Microsc Res Tech 73: 886-900.
25. Sodeik B, Ebersold MW, Helenius A, (1997) Microtubule-mediated transport of incoming herpes simplex virus 1 capsids to the nucleus. J Cell Biol 136: 1007-1021.
26. Valencia SM, Hutt-Fletcher LM, (2011) Important but differential roles for actin in trafficking of EBV in B cells and epithelial cells. J Virol 86: 2-10.
27. Lakadamyali M, Rust MJ, Zhuang X, (2006) Ligands for clathrin-mediated endocytosis are differentially sorted into distinct populations of early endosomes. Cell 124: 997-1009.
28. Sakai T, Ohuchi M, Imai M, Mizuno T, Kawasaki K, et al. (2006) Dual wavelength imaging allows analysis of membrane fusion of influenza virus inside cells. J Virol 80: 2013-2018.
29. McDonald D, Vodicka MA, Lucero G, Svitkina TM, Borisy GG, et al. (2002) Visualization of the intracellular behavior of HIV in living cells. J Cell Biol 159: 441-452.
30. Bowman EJ, Siebers A, Altendorf K, (1988) Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells. Proc Natl Acad Sci U S A 85: 7972-7976.
31. Sieczkarski SB, Whittaker GR, (2003) Differential requirements of Rab5 and Rab7 for endocytosis of influenza and other enveloped viruses. Traffic 4: 333-343.
32. Vonderheit A, Helenius A, (2005) Rab7 associates with early endosomes to mediate sorting and transport of Semliki forest virus to late endosomes. PLoS Biol 3: 1225-1238.
33. Urayama A, Grubb JH, Sly WS, Banks WA, (2004) Developmentally regulated mannose 6-phosphate receptor-mediated transport of a lysosomal enzyme across the blood-brain barrier. Proc Natl Acad Sci U S A 101: 12658-12663.
34. Levine B, Klionsky DJ, (2004) Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 6: 463-477.
35. Levine B, Kroemer G, (2008) Autophagy in the pathogenesis of disease. Cell 132: 27-42.
36. Shoji-Kawata S, Levine B, (2009) Autophagy, antiviral immunity, and viral countermeasures. Biochim Biophys Acta 1793: 1478-1484.
37. Orvedahl A, Levine B, (2008) Autophagy and viral neurovirulence. Cell Microbiol 10: 1747-1756.
38. Shelly S, Lukinova N, Bambina S, Berman A, Cherry S, (2009) Autophagy is an essential component of drosophila immunity against vesicular stomatitis virus. Immunity 30: 588-598.
39. Wong J, Zhang J, Si X, Gao G, Mao I, et al. (2008) Autophagosome supports coxsackievirus B3 replication in host cells. J Virol 82: 9143-9153.
40. Kyei GB, Dinkins C, Davis AS, Roberts E, Singh SB, et al. (2009) Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages. J Cell Biol 186: 255-268.
41. Gougeon ML, Piacentini M, (2009) New insights on the role of apoptosis and autophagy in HIV pathogenesis. Apoptosis 14: 501-508.
42. Espert L, Codogno P, Biard-Piechaczyk M, (2008) What is the role of autophagy in HIV-1 infection? Autophagy 4: 273-275.
43. Espert L, Denizot M, Grimaldi M, Robert-Hebmann V, Gay B, et al. (2006) Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4. J Clin Invest 116: 2161-2172.
44. Brabec-Zaruba M, Berka U, Blaas D, Fuchs R, (2007) Induction of autophagy does not affect human rhinovirus type 2 production. J Virol 81: 10815-10817.
45. Xie Z, Klionsky DJ, (2007) Autophagosome formation: core machinery and adaptations. Nat Cell Biol 9: 1102-1109.
46. DeTulleo L, Kirchhausen T, (1998) The clathrin endocytic pathway in viral infection. EMBO J 17: 4585-4593.
47. Mercer J, Schelhaas M, Helenius A, (2010) Virus entry by endocytosis. Annu Rev Biochem 79: 803-833.
48. Liu Y, Joo K, Wang P (2012) Endocytic processing of adeno-associated virus type 8 vectors for transduction of target cells. Gene Ther.
49. Marsh M, Helenius A, (1989) Virus entry into animal cells. Adv Virus Res 36: 107-151.
50. Cambi A, Lidke DS, Arndt-Jovin DJ, Figdor CG, Jovin TM, (2007) Ligand-Conjugated Quantum Dots Monitor Antigen Uptake and Processing by Dendritic Cells. Nano Lett 7: 970-977.
51. Lozach PY, Kühbacher A, Meier R, Mancini R, Bitto D, et al. (2011) DC-SIGN as a receptor for phleboviruses. Cell Host Microbe 10: 75-88.
52. Cambi A, Beeren I, Joosten B, Fransen JA, Figdor CG, (2009) The C-type lectin DC-SIGN internalizes soluble antigens and HIV-1 virions via a clathrin-dependent mechanism. Eur J Immunol 39: 1923-1928.
53. Maxfield FR, McGraw TE, (2004) Endocytic recycling. Nat Rev Mol Cell Biol 5: 121-132.
54. Sieczkarski SB, Whittaker GR, (2002) Dissecting virus entry via endocytosis. J Gen Virol 83: 1535-1545.
55. Marsh M, Helenius A (2006) Virus Entry: Open Sesame. Cell 124.
56. Vonderheit A, Helenius A (2005) Rab7 associates with early en- dosomes to mediate sorting and transport of Semliki forest virus to late endosomes. PLoS Biol 3.
57. Smit JM, Bittman R, Wilschut J, (1999) Low-pH-dependent fusion of Sindbis virus with receptor-free cholesterol- and sphingolipid-containing liposomes. J Virol 73: 8476-8484.
58. Chernomordik LV, Frolov VA, Leikina E, Bronk P, Zimmerberg J, (1998) The pathway of membrane fusion catalyzed by influenza hemagglutinin: restriction of lipids, hemifusion, and lipidic fusion pore formation. J Cell Biol 140: 1369-1382.
59. White J, Helenius A, (1980) pH-dependent fusion between the Semliki Forest virus membrane and liposomes. Proc Natl Acad Sci USA 77: 3273-3277.
60. Kyei GB, Dinkins C, Davis AS, Roberts E, Singh SB, et al. (2009) Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages. J Cell Biol 186: 255-268.
61. Kudchodkar SB, Levine B, (2009) Viruses and autophagy. Rev Med Virol 19: 359-378.
62. Tanida I, Waguri S, (2010) Measurement of autophagy in cells and tissues. Methods Mol Biol 648: 193-214.
63. Mizushima N, Yoshimori T, Levine B, (2010) Methods in mammalian autophagy research. Cell 140: 313-326.