Fluorescence anisotropy uncovers changes in protein packing with inclusion growth in a cellular model of polyglutamine aggregation

Biochemistry

Volumn 53, Issue 22, 2014, Pages 3621-3636

  Bhardwaj, Vishal ^a   Panicker, Mitradas M ^a   Udgaonkar, Jayant B ^a  

^a TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AGGREGATES; ANISOTROPY; ENERGY TRANSFER; FLUORESCENCE; MOLECULES;

ENHANCED GREEN FLUORESCENT PROTEIN; FLUORESCENCE ANISOTROPY; INVERSE CORRELATION; NEURODEGENERATIVE DISORDERS; POSSIBLE MECHANISMS; RESONANCE ENERGY TRANSFER; STEADY-STATE ANISOTROPY; TIME RESOLVED FLUORESCENCE ANISOTROPY;

PROTEINS;

ENHANCED GREEN FLUORESCENT PROTEIN; POLYGLUTAMINE;

ANISOTROPY; ARTICLE; BRIGHTNESS; CELL GROWTH; CELL INCLUSION; CELL SIZE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENSITY; DEPOLARIZATION; EMBRYO; EMISSION ANISOTROPY; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEK293 CELL LINE; HUMAN; HUMAN CELL; INCLUSION GROWTH; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PACKING; PROTEIN STRUCTURE; STEADY STATE; TRANSIENT EXPRESSION;

FLUORESCENCE POLARIZATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; INCLUSION BODIES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; PEPTIDES; PROTEIN FOLDING;

EID: 84902192912     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500383h     Document Type: Article

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