메뉴 건너뛰기




Volumn 2014, Issue , 2014, Pages

Abdominal fat and sarcopenia in women significantly alter osteoblasts homeostasis in vitro by a WNT/ β -catenin dependent mechanism

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BETA CATENIN; BONE MORPHOGENETIC PROTEIN 4; GLYCOGEN SYNTHASE KINASE 3BETA; MESSENGER RNA; OSTEOPONTIN; WNT PROTEIN;

EID: 84902156360     PISSN: 16878337     EISSN: 16878345     Source Type: Journal    
DOI: 10.1155/2014/278316     Document Type: Article
Times cited : (13)

References (50)
  • 1
    • 0036945834 scopus 로고    scopus 로고
    • Obesity: The disease of the twenty-first century
    • Rossner S., Obesity: the disease of the twenty-first century. International Journal of Obesity and Related Metabolic Disorders 2002 26, supplement 4 S2 S4 (Pubitemid 36071962)
    • (2002) International Journal of Obesity , vol.26 , Issue.SUPPL. 4
    • Rossner, S.1
  • 2
    • 0035857351 scopus 로고    scopus 로고
    • Osteoporosis prevention, diagnosis, and therapy
    • Consensus Development Panel On Osteoporosis Prevention Diagnosis And Therapy
    • NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy, Osteoporosis prevention, diagnosis, and therapy. The Journal of the American Medical Association 2001 285 6 785 795
    • (2001) The Journal of the American Medical Association , vol.285 , Issue.6 , pp. 785-795
  • 3
    • 0027310187 scopus 로고
    • Effects of weight and body mass index on bone mineral density in men and women: The Framingham study
    • Felson D. T., Zhang Y., Hannan M. T., Anderson J. J., Effects of weight and body mass index on bone mineral density in men and women: the Framingham study. Journal of Bone and Mineral Research 1993 8 5 567 573 2-s2.0-0027310187 (Pubitemid 23127916)
    • (1993) Journal of Bone and Mineral Research , vol.8 , Issue.5 , pp. 567-573
    • Felson, D.T.1    Zhang, Y.2    Hannan, M.T.3    Anderson, J.J.4
  • 5
    • 0036712047 scopus 로고    scopus 로고
    • Mechanical strain and bone cell function: A review
    • DOI 10.1007/s001980200095
    • Ehrlich P. J., Lanyon L. E., Mechanical strain and bone cell function: a review. Osteoporosis International 2002 13 9 688 700 2-s2.0-0036712047 10.1007/s001980200095 (Pubitemid 35000996)
    • (2002) Osteoporosis International , vol.13 , Issue.9 , pp. 688-700
    • Ehrlich, P.J.1    Lanyon, L.E.2
  • 8
    • 77957941579 scopus 로고    scopus 로고
    • Relation between obesity and bone mineral density and vertebral fractures in Korean postmenopausal women
    • 2-s2.0-77957941579 10.3349/ymj.2010.51.6.857
    • Kim K.-C., Shin D.-H., Lee S.-Y., Im J.-A., Lee D.-C., Relation between obesity and bone mineral density and vertebral fractures in Korean postmenopausal women. Yonsei Medical Journal 2010 51 6 857 863 2-s2.0-77957941579 10.3349/ymj.2010.51.6.857
    • (2010) Yonsei Medical Journal , vol.51 , Issue.6 , pp. 857-863
    • Kim, K.-C.1    Shin, D.-H.2    Lee, S.-Y.3    Im, J.-A.4    Lee, D.-C.5
  • 9
    • 0035464415 scopus 로고    scopus 로고
    • The adipose organ: Endocrine aspects and insights from transgenic models
    • 2-s2.0-0035464415
    • Cinti S., The adipose organ: endocrine aspects and insights from transgenic models. Eating and Weight Disorders 2001 6, supplement 3 4 8 2-s2.0-0035464415
    • (2001) Eating and Weight Disorders , vol.6 , Issue.3 , pp. 4-8
    • Cinti, S.1
  • 10
    • 66349115342 scopus 로고    scopus 로고
    • Adipocyte metabolism and obesity
    • 2-s2.0-66349115342 10.1194/jlr.R800057-JLR200
    • Attie A. D., Scherer P. E., Adipocyte metabolism and obesity. Journal of Lipid Research 2009 50, supplement S395 S399 2-s2.0-66349115342 10.1194/jlr.R800057-JLR200
    • (2009) Journal of Lipid Research , vol.50
    • Attie, A.D.1    Scherer, P.E.2
  • 11
    • 29744458790 scopus 로고    scopus 로고
    • Adipose tissue as source and target for novel therapies
    • DOI 10.1016/j.tem.2005.11.008, PII S1043276005002626
    • Klein J., Perwitz N., Kraus D., Fasshauer M., Adipose tissue as source and target for novel therapies. Trends in Endocrinology and Metabolism 2006 17 1 26 32 2-s2.0-29744458790 10.1016/j.tem.2005.11.008 (Pubitemid 43031381)
    • (2006) Trends in Endocrinology and Metabolism , vol.17 , Issue.1 , pp. 26-32
    • Klein, J.1    Perwitz, N.2    Kraus, D.3    Fasshauer, M.4
  • 12
    • 49649118727 scopus 로고    scopus 로고
    • The bone-adipose axis in obesity and weight loss
    • 10.1007/s11695-008-9548-1
    • Gómez-Ambrosi J., Rodríguez A., Catalán V., Frühbeck G., The bone-adipose axis in obesity and weight loss. Obesity Surgery 2008 18 9 1134 1143 10.1007/s11695-008-9548-1
    • (2008) Obesity Surgery , vol.18 , Issue.9 , pp. 1134-1143
    • Gómez-Ambrosi, J.1    Rodríguez, A.2    Catalán, V.3    Frühbeck, G.4
  • 14
    • 2942650969 scopus 로고    scopus 로고
    • Adipose tissue as an endocrine organ
    • DOI 10.1210/jc.2004-0395
    • Kershaw E. E., Flier J. S., Adipose tissue as an endocrine organ. Journal of Clinical Endocrinology and Metabolism 2004 89 6 2548 2556 2-s2.0-2942650969 10.1210/jc.2004-0395 (Pubitemid 38766330)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.6 , pp. 2548-2556
    • Kershaw, E.E.1    Flier, J.S.2
  • 19
    • 84860340478 scopus 로고    scopus 로고
    • Minireview: The link between fat and bone: Does mass beget mass?
    • 2-s2.0-84860340478 10.1210/en.2012-1022
    • Zaidi M., Buettner C., Sun L., Iqbal J., Minireview: the link between fat and bone: does mass beget mass? Endocrinology 2012 153 5 2070 2075 2-s2.0-84860340478 10.1210/en.2012-1022
    • (2012) Endocrinology , vol.153 , Issue.5 , pp. 2070-2075
    • Zaidi, M.1    Buettner, C.2    Sun, L.3    Iqbal, J.4
  • 20
    • 84862744882 scopus 로고    scopus 로고
    • The endocrine role of the skeleton: Background and clinical evidence
    • 10.1530/EJE-12-0030
    • Schwetz V., Pieber T., Obermayer-Pietsch B., The endocrine role of the skeleton: background and clinical evidence. European Journal of Endocrinology 2012 166 6 959 967 10.1530/EJE-12-0030
    • (2012) European Journal of Endocrinology , vol.166 , Issue.6 , pp. 959-967
    • Schwetz, V.1    Pieber, T.2    Obermayer-Pietsch, B.3
  • 21
    • 34848902631 scopus 로고    scopus 로고
    • Associations of plasma fibrinogen levels with established cardiovascular disease risk factors, inflammatory markers, and other characteristics: Individual participant meta-analysis of 154,211 adults in 31 prospective studies
    • DOI 10.1093/aje/kwm191
    • Kaptoge S., Kaptoge S., White I. R., Thompson S. G., Wood A. M., Lewington S., Lowe G. D. O., Danesh J., Associations of plasma fibrinogen levels with established cardiovascular disease risk factors, inflammatory markers, and other characteristics: individual participant meta-analysis of 154,211 adults in 31 prospective studies. The American Journal of Epidemiology 2007 166 8 867 879 2-s2.0-34848902631 10.1093/aje/kwm191 (Pubitemid 47511690)
    • (2007) American Journal of Epidemiology , vol.166 , Issue.8 , pp. 867-879
    • Kaptoge, S.1    Kaptoge, S.2    White, I.R.3    Thompson, S.G.4    Wood, A.M.5    Lewington, S.6    Lowe, G.D.O.7    Danesh, J.8
  • 22
    • 40849097785 scopus 로고    scopus 로고
    • Osteopontin expression in human and murine obesity: Extensive local up-regulation in adipose tissue but minimal systemic alterations
    • DOI 10.1210/en.2007-1312
    • Kiefer F. W., Zeyda M., Todoric J., Huber J., Geyeregger R., Weichhart T., Aszmann O., Ludvik B., Silberhumer G. R., Prager G., Stulnig T. M., Osteopontin expression in human and murine obesity: extensive local up-regulation in adipose tissue but minimal systemic alterations. Endocrinology 2008 149 3 1350 1357 2-s2.0-40849097785 10.1210/en.2007-1312 (Pubitemid 351397930)
    • (2008) Endocrinology , vol.149 , Issue.3 , pp. 1350-1357
    • Kiefer, F.W.1    Zeyda, M.2    Todoric, J.3    Huber, J.4    Geyeregger, R.5    Weichhart, T.6    Aszmann, O.7    Ludvik, B.8    Silberhumer, G.R.9    Prager, G.10    Stulnig, T.M.11
  • 24
    • 84860273372 scopus 로고    scopus 로고
    • Relations between obesity, insulin resistance, and 25-hydroxyvitamin D
    • 2-s2.0-84860273372 10.3945/ajcn.111.032060
    • Lamendola C. A., Ariel D., Feldman D., Reaven G. M., Relations between obesity, insulin resistance, and 25-hydroxyvitamin D. The American Journal of Clinical Nutrition 2012 95 5 1055 1059 2-s2.0-84860273372 10.3945/ajcn.111. 032060
    • (2012) The American Journal of Clinical Nutrition , vol.95 , Issue.5 , pp. 1055-1059
    • Lamendola, C.A.1    Ariel, D.2    Feldman, D.3    Reaven, G.M.4
  • 26
    • 0019304735 scopus 로고
    • The effect of 6 weeks of overfeeding on the body weight, body composition, and energy metabolism of young men
    • Norgan N. G., Durnin J. V. G. A., The effect of 6 weeks of overfeeding on the body weight, body composition, and energy metabolism of young men. The American Journal of Clinical Nutrition 1980 33 5 978 988 2-s2.0-0019304735 (Pubitemid 10040629)
    • (1980) American Journal of Clinical Nutrition , vol.33 , Issue.5 , pp. 978-988
    • Norgan, N.G.1    Durnin, J.V.G.A.2
  • 27
    • 84883174365 scopus 로고    scopus 로고
    • Negative association between trunk fat, insuline resistance and skeleton in obese women
    • 10.4239/wjd.v4.i2.31
    • Greco E. A., Francomano D., Fornari R., Marocco C., Lubrano C., Papa V., Negative association between trunk fat, insuline resistance and skeleton in obese women. World Journal of Diabetes 2013 4 2 31 39 10.4239/wjd.v4.i2.31
    • (2013) World Journal of Diabetes , vol.4 , Issue.2 , pp. 31-39
    • Greco, E.A.1    Francomano, D.2    Fornari, R.3    Marocco, C.4    Lubrano, C.5    Papa, V.6
  • 28
    • 84890058193 scopus 로고    scopus 로고
    • Trunk fat negatively influences skeletal and testicular functions in obese men: Clinical implications for the aging male
    • 182753 10.1155/2013/182753
    • Migliaccio S., Francomano D., Bruzziches R., Trunk fat negatively influences skeletal and testicular functions in obese men: clinical implications for the aging male. International Journal of Endocrinology 2013 2013 6 182753 10.1155/2013/182753
    • (2013) International Journal of Endocrinology , vol.2013 , pp. 6
    • Migliaccio, S.1    Francomano, D.2    Bruzziches, R.3
  • 29
    • 49349110946 scopus 로고    scopus 로고
    • Androgen receptor expression during C2C12 skeletal muscle cell line differentiation
    • 2-s2.0-49349110946 10.1016/j.mce.2008.05.018
    • Wannenes F., Caprio M., Gatta L., Fabbri A., Bonini S., Moretti C., Androgen receptor expression during C2C12 skeletal muscle cell line differentiation. Molecular and Cellular Endocrinology 2008 292 1-2 11 19 2-s2.0-49349110946 10.1016/j.mce.2008.05.018
    • (2008) Molecular and Cellular Endocrinology , vol.292 , Issue.1-2 , pp. 11-19
    • Wannenes, F.1    Caprio, M.2    Gatta, L.3    Fabbri, A.4    Bonini, S.5    Moretti, C.6
  • 30
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak K. J., Schmittgen T. D., Analysis of relative gene expression data using real-time quantitative PCR and the 2-Δ Δ C t method. Methods 2001 25 4 402 408 2-s2.0-0035710746 10.1006/meth.2001.1262 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 31
    • 0027131418 scopus 로고
    • Osteopontin: A protein with diverse functions
    • Denhardt D. T., Guo X., Osteopontin: a protein with diverse functions. The FESAB Journal 1993 7 15 1475 1482 2-s2.0-0027131418 (Pubitemid 24003267)
    • (1993) FASEB Journal , vol.7 , Issue.15 , pp. 1475-1482
    • Denhardt, D.T.1    Guo, X.2
  • 34
    • 84873688688 scopus 로고    scopus 로고
    • The value of osteopontin in the assessment of bone mineral density status in postmenopausal women
    • 10.231/JIM.0b013e3182761264
    • Fodor D., Bondor C., Albu A., Simon S. P., Craciun A., Muntean L., The value of osteopontin in the assessment of bone mineral density status in postmenopausal women. Journal of Investigative Medicine 2013 61 1 15 21 10.231/JIM.0b013e3182761264
    • (2013) Journal of Investigative Medicine , vol.61 , Issue.1 , pp. 15-21
    • Fodor, D.1    Bondor, C.2    Albu, A.3    Simon, S.P.4    Craciun, A.5    Muntean, L.6
  • 36
    • 5044228112 scopus 로고    scopus 로고
    • Wnt signaling in osteoblasts and bone diseases
    • DOI 10.1016/j.gene.2004.06.044, PII S0378111904003853
    • Westendorf J. J., Kahler R. A., Schroeder T. M., Wnt signaling in osteoblasts and bone diseases. Gene 2004 341 1-2 19 39 2-s2.0-5044228112 10.1016/j.gene.2004.06.044 (Pubitemid 39335880)
    • (2004) Gene , vol.341 , Issue.1-2 , pp. 19-39
    • Westendorf, J.J.1    Kahler, R.A.2    Schroeder, T.M.3
  • 37
    • 77954210220 scopus 로고    scopus 로고
    • An updated overview on wnt signaling pathways: A prelude for more
    • 2-s2.0-77954210220 10.1161/CIRCRESAHA.110.219840
    • Rao T. P., Kühl M., An updated overview on wnt signaling pathways: a prelude for more. Circulation Research 2010 106 12 1798 1806 2-s2.0-77954210220 10.1161/CIRCRESAHA.110.219840
    • (2010) Circulation Research , vol.106 , Issue.12 , pp. 1798-1806
    • Rao, T.P.1    Kühl, M.2
  • 38
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/ β -catenin signaling: Components, mechanisms, and diseases
    • 2-s2.0-67650230896 10.1016/j.devcel.2009.06.016
    • MacDonald B. T., Tamai K., He X., Wnt/ β -catenin signaling: components, mechanisms, and diseases. Developmental Cell 2009 17 1 9 26 2-s2.0-67650230896 10.1016/j.devcel.2009.06.016
    • (2009) Developmental Cell , vol.17 , Issue.1 , pp. 9-26
    • Macdonald, B.T.1    Tamai, K.2    He, X.3
  • 39
    • 84882636723 scopus 로고    scopus 로고
    • Analysing the impact of nucleo-cytoplasmic shuttling of β -catenin and its antagonists APC, Axin and GSK3 on Wnt/ β -catenin signalling
    • 10.1016/j.cellsig.2013.07.005
    • Schmitz Y., Rateitschak K., Wolkenhauer O., Analysing the impact of nucleo-cytoplasmic shuttling of β -catenin and its antagonists APC, Axin and GSK3 on Wnt/ β -catenin signalling. Cell Signal 2013 25 11 2210 2221 10.1016/j.cellsig.2013.07.005
    • (2013) Cell Signal , vol.25 , Issue.11 , pp. 2210-2221
    • Schmitz, Y.1    Rateitschak, K.2    Wolkenhauer, O.3
  • 40
    • 0031741171 scopus 로고    scopus 로고
    • Effect of obesity on estradiol level, and its relationship to leptin, bone maturation, and bone mineral density in children
    • DOI 10.1210/jc.83.10.3469
    • Klein K. O., Larmore K. A., de Lancey E., Brown J. M., Considine R. V., Hassink S. G., Effect of obesity on estradiol level, and its relationship to leptin, bone maturation, and bone mineral density in children. Journal of Clinical Endocrinology and Metabolism 1998 83 10 3469 3475 2-s2.0-0031741171 10.1210/jc.83.10.3469 (Pubitemid 28500873)
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , Issue.10 , pp. 3469-3475
    • Klein, K.O.1    Larmore, K.A.2    De Lancey, E.3    Brown, J.M.4    Considine, R.V.5    Hassink, S.G.6
  • 41
    • 84878495700 scopus 로고    scopus 로고
    • Abdominal fat is associated with lower bone formation and inferior bone quality in healthy premenopausal women: A transiliac bone biopsy study
    • 10.1210/jc.2013-1047
    • Cohen A., Dempster D. W., Recker R. R., Lappe J. M., Zhou H., Zwahlen A., Abdominal fat is associated with lower bone formation and inferior bone quality in healthy premenopausal women: a transiliac bone biopsy study. Journal of Clinical Endocrinology and Metabolism 2013 98 6 2562 2572 10.1210/jc.2013-1047
    • (2013) Journal of Clinical Endocrinology and Metabolism , vol.98 , Issue.6 , pp. 2562-2572
    • Cohen, A.1    Dempster, D.W.2    Recker, R.R.3    Lappe, J.M.4    Zhou, H.5    Zwahlen, A.6
  • 44
    • 79958772684 scopus 로고    scopus 로고
    • Effects of obesity on bone metabolism
    • 10.1186/1749-799X-6-30
    • Cao J. J., Effects of obesity on bone metabolism. Journal of Orthopaedic Surgery and Research 2011 15 6 30 10.1186/1749-799X-6-30
    • (2011) Journal of Orthopaedic Surgery and Research , vol.15 , pp. 6-30
    • Cao, J.J.1
  • 45
    • 79951792447 scopus 로고    scopus 로고
    • Signaling networks in RUNX2-dependent bone development
    • 2-s2.0-79951792447 10.1002/jcb.22994
    • Komori T., Signaling networks in RUNX2-dependent bone development. Journal of Cellular Biochemistry 2011 112 3 750 755 2-s2.0-79951792447 10.1002/jcb.22994
    • (2011) Journal of Cellular Biochemistry , vol.112 , Issue.3 , pp. 750-755
    • Komori, T.1
  • 46
    • 84884593334 scopus 로고    scopus 로고
    • Wnt signalling in osteoporosis: Mechanisms and novel therapeutic approaches
    • 10.1038/nrendo.2013.154
    • Canalis E., Wnt signalling in osteoporosis: mechanisms and novel therapeutic approaches. Nature Reviews Endocrinology 2013 9 10 575 583 10.1038/nrendo.2013.154
    • (2013) Nature Reviews Endocrinology , vol.9 , Issue.10 , pp. 575-583
    • Canalis, E.1
  • 47
    • 0038485600 scopus 로고    scopus 로고
    • Lymphoid enhancer factor-1 and β-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter
    • DOI 10.1074/jbc.M211443200
    • Kahler R. A., Westendorf J. J., Lymphoid enhancer factor-1 and β -catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter. The Journal of Biological Chemistry 2003 278 14 11937 11944 2-s2.0-0038485600 10.1074/jbc.M211443200 (Pubitemid 36800167)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.14 , pp. 11937-11944
    • Kahler, R.A.1    Westendorf, J.J.2
  • 48
    • 33645243606 scopus 로고    scopus 로고
    • Lymphocyte enhancer-binding factor 1 (Lef1) inhibits terminal differentiation of osteoblasts
    • 2-s2.0-33645243606 10.1002/jcb.20702
    • Kahler R. A., Galindo M., Lian J., Stein G. S., van Wijnen A. J., Westendorf J. J., Lymphocyte enhancer-binding factor 1 (Lef1) inhibits terminal differentiation of osteoblasts. Journal of Cellular Biochemistry 2006 97 5 969 983 2-s2.0-33645243606 10.1002/jcb.20702
    • (2006) Journal of Cellular Biochemistry , vol.97 , Issue.5 , pp. 969-983
    • Kahler, R.A.1    Galindo, M.2    Lian, J.3    Stein, G.S.4    Van Wijnen, A.J.5    Westendorf, J.J.6
  • 49
    • 70149125015 scopus 로고    scopus 로고
    • Runx2 and bone morphogenic protein 2 regulate the expression of an alternative lef1 transcript during osteoblast maturation
    • 2-s2.0-70149125015 10.1002/jcp.21879
    • Hoeppner L. H., Secreto F., Jensen E. D., Li X., Kahler R. A., Westendorf J. J., Runx2 and bone morphogenic protein 2 regulate the expression of an alternative lef1 transcript during osteoblast maturation. Journal of Cellular Physiology 2009 221 2 480 489 2-s2.0-70149125015 10.1002/jcp.21879
    • (2009) Journal of Cellular Physiology , vol.221 , Issue.2 , pp. 480-489
    • Hoeppner, L.H.1    Secreto, F.2    Jensen, E.D.3    Li, X.4    Kahler, R.A.5    Westendorf, J.J.6
  • 50
    • 79953231681 scopus 로고    scopus 로고
    • Lef1ΔN binds β -catenin and increases osteoblast activity and trabecular bone mass
    • 2-s2.0-79953231681 10.1074/jbc.M110.165100
    • Hoeppner L. H., Secreto F. J., Razidlo D. F., Whitney T. J., Westendorf J. J., Lef1ΔN binds β -catenin and increases osteoblast activity and trabecular bone mass. The Journal of Biological Chemistry 2011 286 13 10950 10959 2-s2.0-79953231681 10.1074/jbc.M110.165100
    • (2011) The Journal of Biological Chemistry , vol.286 , Issue.13 , pp. 10950-10959
    • Hoeppner, L.H.1    Secreto, F.J.2    Razidlo, D.F.3    Whitney, T.J.4    Westendorf, J.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.