Cyclovirobuxine D induces autophagy-associated cell death via the Akt/mTOR pathway in MCF-7 human breast cancer cells

Journal of Pharmacological Sciences

Volumn 125, Issue 1, 2014, Pages 74-82

  Lu, Jing ^a   Sun, Duanping ^a   Gao, Si ^a   Gao, Ying ^a   Ye, Jiantao ^a   Liu, Peiqing ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Akt; Autophagy; Breast cancer; Cyclovirobuxine D; mTOR

Indexed keywords

3 METHYLADENINE; AUTOPHAGY PROTEIN 5; CYCLOVIROBUXINE D; MAMMALIAN TARGET OF RAPAMYCIN; PARAPROTEIN; PROTEIN KINASE B; PROTEIN LC3; UNCLASSIFIED DRUG;

ARTICLE; AUTOLYSOSOME; AUTOPHAGY; BREAST CANCER CELL LINE; CELL ACTIVATION; CELL DEATH; CELL MIGRATION; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MCF 7 CELL LINE; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

ADENINE; AUTOPHAGY; BREAST NEOPLASMS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; FEMALE; HUMANS; MCF-7 CELLS; MICROTUBULE-ASSOCIATED PROTEINS; MOLECULAR TARGETED THERAPY; PHOSPHORYLATION; PHYTOTHERAPY; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84902134638     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.14013FP     Document Type: Article

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