Total alkaloids of Tripterygium hypoglaucum (levl.) Hutch inhibits tumor growth both in vitro and in vivo

Journal of Ethnopharmacology

Volumn 151, Issue 1, 2014, Pages 292-298

  Jiang, Xiao ^a   Huang, Xiao Chun ^a   Ao, Lin ^a   Liu, Wen Bin ^a   Han, Fei ^a   Cao, Jia ^a   Zhang, Dong Yun ^b   Huang, Chuan Shu ^b   Liu, Jin Yi ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alkaloid; Apoptosis; Traditional Chinese medicine; Tripterygium hypoglaucum (levl.) Hutch

Indexed keywords

ALKALOID; ANTINEOPLASTIC AGENT; CASPASE 3; PLANT EXTRACT; PROTEIN BCL 2; PROTEIN BCL XL; TRIPTERYGIUM HYPOGLAUCUM EXTRACT; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER MODEL; CELL STRAIN HCT116; CELL TRANSFORMATION; COLON CANCER; COLONY FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MALIGNANT TRANSFORMATION; MOUSE; MOUSE MODEL; MTT ASSAY; NONHUMAN; PILOT STUDY; PLANT ROOT; TRIPTERYGIUM HYPOGLAUCUM; TUMOR GROWTH; TUMOR XENOGRAFT; WESTERN BLOTTING; XENOGRAFT;

CELASTRACEAE; MUS; TRIPTERYGIUM HYPOGLAUCUM;

12-O-TETRADECANOG 1 PHORBOL-13-ACETATE; ALKALOID; APOPTOSIS; B-CELL LYMPHOMA 2; B-CELL LYMPHOMA-EXTRA LARGE; BCL-2; BCL-XL; DEATH-INDUCING SIGNALING COMPLEX; DIMETHYL SULFOXIDE; DISC; DMSO; FADD; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FBS; FETAL BOVINE SERUM; HE; HEMATOXYLIN AND EOSIN; PARP; POLY ADP-RIBOSE POLYMERASE; TBST; THH; THHTA; TNF RECEPTOR ASSOCIATED DEATH DOMAIN; TOTAL ALKALOIDS OF TRIPTERYGIUM HYPOGLAUCUM (LEVL.) HUTCH (CELASTRACEAE); TPA; TRADD; TRADITIONAL CHINESE MEDICINE; TRIPTERYGIUM HYPOGLAUCUM (LEVL.) HUTCH; TRIPTERYGIUM HYPOGLAUCUM (LEVL.) HUTCH (CELASTRACEAE); TRIS BUFFERED SALINE TWEEN; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN; XIAP;

ALKALOIDS; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HCT116 CELLS; HUMANS; MALE; MICE; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; PLANT ROOTS; TRIPTERYGIUM;

EID: 84891486884     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.10.045     Document Type: Article

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