The histone acetylranseferase hMOF acetylates Nrf2 and regulates anti-drug responses in human non-small cell lung cancer

British Journal of Pharmacology

Volumn 171, Issue 13, 2014, Pages 3196-3211

  Chen, Zhiwei ^a   Ye, Xiangyun ^a   Tang, Naiwang ^a   Shen, Shengping ^a   Li, Ziming ^a   Niu, Xiaomin ^a   Lu, Shun ^a   Xu, Ling ^b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b LONGHUA HOSPITAL AFFILIATED TO SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

acetylation; drug resistance; hMOF; Nrf2; NSCLC; oxidative stress

Indexed keywords

CISPLATIN; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE HMOF; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; KAT8 PROTEIN, HUMAN;

ADVANCED CANCER; AGED; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER PROGNOSIS; CANCER RESISTANCE; CANCER STAGING; CANCER SURVIVAL; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORRELATIONAL STUDY; DOWN REGULATION; DRUG TARGETING; ENZYME ACTIVITY; ENZYME SUBSTRATE; FEMALE; FIBROBLAST; GENE INTERACTION; GENE LOCATION; GENE OVEREXPRESSION; HISTONE ACETYLATION; HMOF GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LUNG NON SMALL CELL CANCER; MALE; METASTASIS POTENTIAL; MOUSE; NONHUMAN; NRF2 GENE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION; TUMOR VOLUME; ACETYLATION; ANIMAL; CARCINOMA, NON-SMALL-CELL LUNG; CELL CULTURE; DRUG RESISTANCE; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; LUNG NEOPLASMS; METABOLISM; MIDDLE AGED; NUDE MOUSE; PATHOLOGY; SURVIVAL RATE; TUMOR CELL LINE;

ACETYLATION; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELLS, CULTURED; DRUG RESISTANCE, NEOPLASM; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HISTONE ACETYLTRANSFERASES; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; MIDDLE AGED; NEOPLASM STAGING; NF-E2-RELATED FACTOR 2; SURVIVAL RATE;

EID: 84902121544     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12661     Document Type: Article

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