HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels

Oncotarget

Volumn 5, Issue 10, 2014, Pages 3234-3245

  Puca, Francesca ^a   Colamaio, Marianna ^a   Federico, Antonella ^a   Gemei, Marica ^b   Tosti, Nadia ^a   Bastos, André Uchimura ^a   Del Vecchio, Luigi ^b   Pece, Salvatore ^c   Battista, Sabrina ^a   Fusco, Alfredo ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

^c EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

Author keywords

Cancer stem cells; Colon carcinoma; HMGA1; NUMB; P53

Indexed keywords

HIGH MOBILITY GROUP A1 PROTEIN; NUCLEAR PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG; HIGH MOBILITY GROUP A1A PROTEIN; SMALL INTERFERING RNA; TP53 PROTEIN, HUMAN;

ARTICLE; CANCER STEM CELL; CELL ACTIVITY; CELL DIVISION; CELL RENEWAL; COLON CANCER; CONTROLLED STUDY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; TRANSCRIPTION REGULATION; UPREGULATION; BIOSYNTHESIS; CHROMATIN IMMUNOPRECIPITATION; COLON TUMOR; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; NICK END LABELING; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; COLONIC NEOPLASMS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE KNOCKDOWN TECHNIQUES; HMGA1A PROTEIN; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; NEOPLASTIC STEM CELLS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84902121345     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1914     Document Type: Article

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