메뉴 건너뛰기




Volumn 87, Issue 2, 2014, Pages 127-133

A dangerous duo in adipose tissue: High-mobility group box 1 protein and macrophages

Author keywords

Adipocyte; Adipose tissue; Apoptosis; Cell death; Crown like structure; Damage associated molecular patterns; Danger signals; Diabetes mellitus type 2; Free fatty acids; High mobility group box 1 protein; Inflammation; Insulin resistance; Interleukin 6; Lipid droplets; Lipolysis; Macrophage; Necrosis; Obesity; Pattern recognition receptors; Phagocytosis; Tumor necrosis factor a

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN;

EID: 84902087184     PISSN: 00440086     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (20)

References (41)
  • 1
    • 84902075180 scopus 로고    scopus 로고
    • Obesity World Health Organization. [Internet]. [cited 2014 Jan. Available from3]
    • Health topics. Obesity World Health Organization. [Internet]. [cited 2014 Jan 3]. Available from: http://www.who.int/topics/obesity/en/.
    • Health topics.
  • 2
    • 3543072186 scopus 로고    scopus 로고
    • Overweight, obesity and cancer: Epidemiological evidence and proposed mechanisms
    • Calle EE, Kaaks R. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer. 2004;4(8):579-91.
    • (2004) Nat Rev Cancer. , vol.4 , Issue.8 , pp. 579-591
    • Calle, E.E.1    Kaaks, R.2
  • 4
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest. 2007;117(1):175-84.
    • (2007) J Clin Invest. , vol.117 , Issue.1 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 5
    • 84875143778 scopus 로고    scopus 로고
    • High-mobility group protein B1: A new biomarker of metabolic syndrome in obese children
    • Arrigo T, Chirico V, Salpietro V, Munafo C, Ferrau V, Gitto E, et al. High-mobility group protein B1: a new biomarker of metabolic syndrome in obese children. Eur J Endocrinol. 2013;168(4):631-8.
    • (2013) Eur J Endocrinol. , vol.168 , Issue.4 , pp. 631-638
    • Arrigo, T.1    Chirico, V.2    Salpietro, V.3    Munafo, C.4    Ferrau, V.5    Gitto, E.6
  • 7
    • 0034698830 scopus 로고    scopus 로고
    • High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes
    • Andersson U, Wang H, Palmblad K, Aveberger AC, Bloom O, Erlandsson-Harris H, et al. High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med. 2000;192(4):565-70.
    • (2000) J Exp Med. , vol.192 , Issue.4 , pp. 565-570
    • Andersson, U.1    Wang, H.2    Palmblad, K.3    Aveberger, A.C.4    Bloom, O.5    Erlandsson-Harris, H.6
  • 8
    • 79953066407 scopus 로고    scopus 로고
    • HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection
    • Andersson U, Tracey KJ. HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection. Annu Rev Immunol. 2011;29:139-62.
    • (2011) Annu Rev Immunol. , vol.29 , pp. 139-162
    • Andersson, U.1    Tracey, K.J.2
  • 9
    • 84876800337 scopus 로고    scopus 로고
    • Macrophage biology in development, homeostasis and disease
    • Wynn TA, Chawla A, Pollard JW. Macrophage biology in development, homeostasis and disease. Nature. 2013;496(7446):445-55.
    • (2013) Nature. , vol.496 , Issue.7446 , pp. 445-455
    • Wynn, T.A.1    Chawla, A.2    Pollard, J.W.3
  • 10
    • 33847073149 scopus 로고    scopus 로고
    • Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity
    • Lumeng CN, Deyoung SM, Bodzin JL, Saltiel AR. Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity. Diabetes. 2007;56(1):16-23.
    • (2007) Diabetes. , vol.56 , Issue.1 , pp. 16-23
    • Lumeng, C.N.1    Deyoung, S.M.2    Bodzin, J.L.3    Saltiel, A.R.4
  • 11
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 2004;25(12):677-86.
    • (2004) Trends Immunol. , vol.25 , Issue.12 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5    Locati, M.6
  • 12
    • 27444437321 scopus 로고    scopus 로고
    • Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
    • Cinti S, Mitchell G, Barbatelli G, Murano I, Ceresi E, Faloia E, et al. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res. 2005;46(11):2347-55.
    • (2005) J Lipid Res. , vol.46 , Issue.11 , pp. 2347-2355
    • Cinti, S.1    Mitchell, G.2    Barbatelli, G.3    Murano, I.4    Ceresi, E.5    Faloia, E.6
  • 14
    • 58149347227 scopus 로고    scopus 로고
    • Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes
    • Lumeng CN, DelProposto JB, Westcott DJ, Saltiel AR. Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes. Diabetes. 2008;57(12):3239-46.
    • (2008) Diabetes. , vol.57 , Issue.12 , pp. 3239-3246
    • Lumeng, C.N.1    DelProposto, J.B.2    Westcott, D.J.3    Saltiel, A.R.4
  • 15
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest. 2003;112(12):1821-30.
    • (2003) J Clin Invest. , vol.112 , Issue.12 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3    Tan, G.4    Yang, D.5    Chou, C.J.6
  • 16
    • 33846004396 scopus 로고    scopus 로고
    • Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins
    • Lumeng CN, Deyoung SM, Saltiel AR. Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins. Am J Physiol Endocrinol Metab. 2007;292(1):E166-74.
    • (2007) Am J Physiol Endocrinol Metab. , vol.292 , Issue.1
    • Lumeng, C.N.1    Deyoung, S.M.2    Saltiel, A.R.3
  • 17
    • 77957838795 scopus 로고    scopus 로고
    • Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue
    • Kosteli A, Sugaru E, Haemmerle G, Martin JF, Lei J, Zechner R, et al. Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue. J Clin Invest. 2010;120(10):3466-79.
    • (2010) J Clin Invest. , vol.120 , Issue.10 , pp. 3466-3479
    • Kosteli, A.1    Sugaru, E.2    Haemmerle, G.3    Martin, J.F.4    Lei, J.5    Zechner, R.6
  • 18
    • 77957828290 scopus 로고    scopus 로고
    • In obesity and weight loss, all roads lead to the mighty macrophage
    • Eagle AR, Chawla A. In obesity and weight loss, all roads lead to the mighty macrophage. J Clin Invest. 2010;120(10):3437-40.
    • (2010) J Clin Invest. , vol.120 , Issue.10 , pp. 3437-3440
    • Eagle, A.R.1    Chawla, A.2
  • 19
    • 41749104586 scopus 로고    scopus 로고
    • The inflammatory response to cell death
    • Rock KL, Kono H. The inflammatory response to cell death. Annu Rev Pathol. 2008;3:99-126.
    • (2008) Annu Rev Pathol. , vol.3 , pp. 99-126
    • Rock, K.L.1    Kono, H.2
  • 20
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF
    • Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest. 1998;101(4):890-8.
    • (1998) J Clin Invest. , vol.101 , Issue.4 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3    Freed, P.W.4    Westcott, J.Y.5    Henson, P.M.6
  • 22
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: A renewed sense of self
    • Matzinger P. The danger model: a renewed sense of self. Science. 2002;296(5566):301-5.
    • (2002) Science. , vol.296 , Issue.5566 , pp. 301-305
    • Matzinger, P.1
  • 23
    • 33846990935 scopus 로고    scopus 로고
    • Friendly and dangerous signals: Is the tissue in control?
    • Matzinger P. Friendly and dangerous signals: is the tissue in control? Nat Immunol. 2007;8(1):11-3.
    • (2007) Nat Immunol. , vol.8 , Issue.1 , pp. 11-13
    • Matzinger, P.1
  • 24
    • 33845951211 scopus 로고    scopus 로고
    • DAMPs, PAMPs and alarmins: All we need to know about danger
    • Bianchi ME. DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukocyte Biol. 2007;81(1):1-5.
    • (2007) J Leukocyte Biol. , vol.81 , Issue.1 , pp. 1-5
    • Bianchi, M.E.1
  • 25
    • 35748967851 scopus 로고    scopus 로고
    • High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity
    • Bianchi ME, Manfredi AA. High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity. Immunol Rev. 2007;220:35-46.
    • (2007) Immunol Rev. , vol.220 , pp. 35-46
    • Bianchi, M.E.1    Manfredi, A.A.2
  • 26
    • 63449101111 scopus 로고    scopus 로고
    • Immunology. Dangers in and out
    • Bianchi ME, Manfredi AA. Immunology. Dangers in and out. Science. 2009;323(5922):1683-4.
    • (2009) Science. , vol.323 , Issue.5922 , pp. 1683-1684
    • Bianchi, M.E.1    Manfredi, A.A.2
  • 27
    • 17144376810 scopus 로고    scopus 로고
    • High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
    • Lotze MT, Tracey KJ. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol. 2005;5(4):331-42.
    • (2005) Nat Rev Immunol. , vol.5 , Issue.4 , pp. 331-342
    • Lotze, M.T.1    Tracey, K.J.2
  • 28
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature. 2002;418(6894):191-5.
    • (2002) Nature. , vol.418 , Issue.6894 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 29
    • 1542380035 scopus 로고    scopus 로고
    • Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
    • Park JS, Svetkauskaite D, He QB, Kim JY, Strassheim D, Ishizaka A, et al. Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem. 2004;279(9):7370-7.
    • (2004) J Biol Chem. , vol.279 , Issue.9 , pp. 7370-7377
    • Park, J.S.1    Svetkauskaite, D.2    He, Q.B.3    Kim, J.Y.4    Strassheim, D.5    Ishizaka, A.6
  • 31
    • 79960735393 scopus 로고    scopus 로고
    • Targeted deletion of adipocytes by apoptosis leads to adipose tissue recruitment of alternatively activated M2 macrophages
    • Fischer-Posovszky P, Wang QA, Asterholm IW, Rutkowski JM, Scherer PE. Targeted deletion of adipocytes by apoptosis leads to adipose tissue recruitment of alternatively activated M2 macrophages. Endocrinology. 2011;152(8):3074-81.
    • (2011) Endocrinology. , vol.152 , Issue.8 , pp. 3074-3081
    • Fischer-Posovszky, P.1    Wang, Q.A.2    Asterholm, I.W.3    Rutkowski, J.M.4    Scherer, P.E.5
  • 34
    • 42949088997 scopus 로고    scopus 로고
    • The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance
    • Goossens GH. The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance. Physiol Behav. 2008;94(2):206-18.
    • (2008) Physiol Behav. , vol.94 , Issue.2 , pp. 206-218
    • Goossens, G.H.1
  • 35
    • 0030614893 scopus 로고    scopus 로고
    • Interstitial pH and pO2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation
    • Helmlinger G, Yuan F, Dellian M, Jain RK. Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. Nat Med. 1997;3(2):177-82.
    • (1997) Nat Med. , vol.3 , Issue.2 , pp. 177-182
    • Helmlinger, G.1    Yuan, F.2    Dellian, M.3    Jain, R.K.4
  • 36
    • 34047119110 scopus 로고    scopus 로고
    • Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation
    • Hosogai N, Fukuhara A, Oshima K, Miyata Y, Tanaka S, Segawa K, et al. Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation. Diabetes. 2007;56(4):901-11.
    • (2007) Diabetes. , vol.56 , Issue.4 , pp. 901-911
    • Hosogai, N.1    Fukuhara, A.2    Oshima, K.3    Miyata, Y.4    Tanaka, S.5    Segawa, K.6
  • 37
    • 4944246547 scopus 로고    scopus 로고
    • The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis
    • Greijer AE, van der Wall E. The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis. J Clin Pathol. 2004;57(10):1009-14.
    • (2004) J Clin Pathol. , vol.57 , Issue.10 , pp. 1009-1014
    • Greijer, A.E.1    van der Wall, E.2
  • 38
    • 12144291563 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse
    • Imai T, Takakuwa R, Marchand S, Dentz E, Bornert JM, Messaddeq N, et al. Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse. Proc Natl Acad Sci USA. 2004;101(13):4543-7.
    • (2004) Proc Natl Acad Sci USA. , vol.101 , Issue.13 , pp. 4543-4547
    • Imai, T.1    Takakuwa, R.2    Marchand, S.3    Dentz, E.4    Bornert, J.M.5    Messaddeq, N.6
  • 39
    • 10044265209 scopus 로고    scopus 로고
    • JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species
    • Ventura JJ, Cogswell P, Flavell RA, Baldwin AS, Jr., Davis RJ. JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species. Genes Dev. 2004;18(23):2905-15.
    • (2004) Genes Dev. , vol.18 , Issue.23 , pp. 2905-2915
    • Ventura, J.J.1    Cogswell, P.2    Flavell, R.A.3    Baldwin Jr., A.S.4    Davis, R.J.5
  • 40
    • 84872142459 scopus 로고    scopus 로고
    • JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation
    • Han MS, Jung DY, Morel C, Lakhani SA, Kim JK, Flavell RA, et al. JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation. Science. 2013;339(6116):218-22.
    • (2013) Science. , vol.339 , Issue.6116 , pp. 218-222
    • Han, M.S.1    Jung, D.Y.2    Morel, C.3    Lakhani, S.A.4    Kim, J.K.5    Flavell, R.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.