Enhancement of phagocytosis and cytotoxicity in macrophages by tumor-derived IL-18 stimulation

BMB Reports

Volumn 47, Issue 5, 2014, Pages 286-291

  Henan, Xu ^a   Toyota, Naoka ^a   Yanjiang, Xing ^a   Fujita, Yuuki ^a   Zhijun, Huang ^b   Touma, Maki ^a   Qiong, Wu ^b   Sugimoto, Kenkichi ^a  

^a NIIGATA UNIVERSITY   (Japan)

^b HARBIN INSTITUTE OF TECHNOLOGY   (China)

Author keywords

Angiogenesis; IL 18; Macrophages; Nos2; Phagocytosis

Indexed keywords

CD11B ANTIGEN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 18; INTERLEUKIN 6; NOS2 PROTEIN, MOUSE; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; C3H MOUSE; CELL LINE; CYTOTOXICITY; ENDOTHELIUM CELL; EXPERIMENTAL NEOPLASM; GENE EXPRESSION; GENETICS; IMMUNOLOGY; MACROPHAGE; MACROPHAGE ACTIVATION; METABOLISM; MOUSE; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; TUMOR CELL LINE; VASCULARIZATION;

ANIMALS; ANTIGENS, CD11B; CELL LINE; CELL LINE, TUMOR; CYTOTOXICITY, IMMUNOLOGIC; ENDOTHELIAL CELLS; GENE EXPRESSION; INTERLEUKIN-18; INTERLEUKIN-6; MACROPHAGE ACTIVATION; MACROPHAGES; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C3H; NEOPLASMS, EXPERIMENTAL; NITRIC OXIDE SYNTHASE TYPE II; PHAGOCYTOSIS; RECOMBINANT PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84901986948     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2014.47.5.152     Document Type: Article

References (34)

1. Folkman, J. (1971) Tumor angiogenesis: therapeuticimplications. N. Engl. J. Med. pp 1182-1186.
2. Ding, Y. T., S. Kumar and D. C. Yu (2008) The Role of Endothelial Progenitor Cells in Tumour Vasculogenesis. Pathobiology. 75, 265-273.
3. Murdoch, C., M. Muthana, S. B. Coffelt and C. E. Lewis (2008) The role of myeloid cells in the promotion of tumourangiogenesis. Nature Reviews Cancer. 8, 618-631.
4. Solinas, G., G. Germano, A. Mantovani and P. Allavena (2009) Tumor-associated macrophages (TAM) as major playersof the cancer-related inflammation. J. Leukocyte. Biol. 86, 1065-1073.
5. Sica, A., P. Larghi, A. Mancino, L. Rubino, C. Porta, M. G. Totaro, M. Rimoldi, S. K. Biswas, P. Allavena and A. Mantovani (2008) Macrophage polarization in tumourprogression. Semin. Cancer Biol. 18, 349-355.
6. Micallef, M. J., T. Ohtsuki, K. Kohno, F. Tanabe, S. Ushio, M. Namba, T. Tanimoto, K. Torigoe, M. Fuji, M. Ikeda, S. Fukudaand M. Kurimoto (1996) Interferon-gamma-inducing factorenhances T helper 1 cytokine production by stimulated human T cells: Synergism with interleukin-12 for interferon-gamma production. Eur. J. Immunol. 26, 1647-1651.
7. Ushio, S., M. Namba, T. Okura, K. Hattori, Y. Nukada, K. Akita, F. Tanabe, K. Konishi, M. Micallef, M. Fujii, K. Torigoe, T. Tanimoto, S. Fukuda, M. Ikeda, H. Okamura and M. Kurimoto (1996) Cloning of the cDNA for human IFN-gamma-lnducing factor, expression in Escherichia coli, and studieson the biologic activities of the protein. J. Immunol. 156, 4274-4279.
8. Gu, Y., Kuida, K., Tsutsui, H. and H. K. Ku G (1997) Activationof interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme. Science. 275(5297), 206-209.
9. Tse, B. W. C., P. J. Russell, M. Lochner, I. Forster and C. A. Power (2011) IL-18 Inhibits Growth of Murine Orthotopic Prostate Carcinomas via Both Adaptive and Innate Immune Mechanisms. Plos One. 6, e24241-24212.
10. Zheng, J. N., D. S. Pei, L. J. Mao, X. Y. Liu, F. H. Sun, B. F. Zhang, Y. Q. Liu, J. J. Liu, W. Li and D. Han (2010) Oncolytic adenovirusexpressing interleukin-18 induces significant antitumoreffects against melanoma in mice through inhibitionof angiogenesis. Cancer Gene Ther. 17, 28-36.
11. Stuyt, R. J., M. G. Netea, T. B. Geijtenbeek, B. J. Kullberg, C. A. Dinarello and J. W. van der Meer (2003) Selective regulationof intercellular adhesion molecule-1 expression by interleukin-18 and interleukin-12 on human monocytes. Immunology. 110, 329-334.
12. Morel, J. C., C. C. Park, J. M. Woods and A. E. Koch (2001) A novel role for interleukin-18 in adhesion molecule inductionthrough NF kappa B and phosphatidylinositol (PI) 3-kinase-dependent signal transduction pathways. J. Biol. Chem. 276, 37069-37075.
13. Netea, M. G., B. J. Kullberg, I. Verschueren and J. W. M. Vander Meer (2000) Interleukin-18 induces production of proinflammatorycytokines in mice: no intermediate role for the cytokinesof the tumor necrosis factor family and interleukin-1 beta. Eur. J. Immunol. 30, 3057-3060.
14. Hikosaka, S., I. Hara, H. Miyake, S. Hara and S. Kamidono (2004) Antitumor effect of simultaneous transfer of interleukin-12 and interleukin-18 genes and its mechanism in amouse bladder cancer model. Int. J. Urol. 11, 647-652.
15. Coma, G., R. Pena, J. Blanco, A. Rosell, F. E. Borras, J. A. Este, B. Clotet, L. Ruiz, R. M. E. Parkhouse and M. Bofill (2006) Treatment of monocytes with interleukin (IL)-12 plus IL-18 stimulates survival, differentiation and the production of CXCchemokine ligands (CXCL)8, CXCL9 and CXCL10. Clin. Exp. Immunol. 145, 535-544.
16. Schindler, H., M. B. Lutz, M. Rollinghoff and C. Bogdan (2001) The production of IFN-gamma by IL-12/IL-18-activated macrophagesrequires STAT4 signaling and is inhibited by IL-4. J. Immunol. 166, 3075-3082.
17. Biswas, S. K., A. Sica and C. E. Lewis (2008) Plasticity of macrophagefunction during tumor progression: regulation by distinctmolecular mechanisms. J. Immunol. 180, 2011-2017.
18. Peng, J., J. Y. Tsang, D. Li, N. Niu, D. H. Ho, K. F. Lau, V. C. Lui, J. R. Lamb, Y. Chen and P. K. Tam (2013) Inhibition of TGF-beta signaling in combination with TLR7 ligation re-programsa tumoricidal phenotype in tumor-associatedmacrophages. Cancer Lett. 331, 239-249.
19. Takeda, Y., S. Costa, E. Delamarre, C. Roncal, R. L. de Oliveira, M. L. Squadrito, V. Finisguerra, S. Deschoemaeker, F. Bruyere, M. Wenes, A. Hamm, J. Serneels, J. Magat, T. Bhattacharyya, A. Anisimov, B. F. Jordan, K. Alitalo, P. Maxwell, B. Gallez, Z. W. Zhuang, Y. Saito, M. Simons, M. De Palma and M. Mazzone (2011) Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducingarteriogenesis. Nature. 479, 122-U153.
20. Spence, S., A. Fitzsimons, C. R. Boyd, J. Kessler, D. Fitzgerald, J. Elliott, J. N. Gabhann, S. Smith, A. Sica, E. Hams, S. P. Saunders, C. A. Jefferies, P. G. Fallon, D. F. McAuley, A. Kissenpfennig and J. A. Johnston (2013) Suppressors of cytokinesignaling 2 and 3 diametrically control macrophagepolarization. Immunity. 38, 66-78.
21. Kim, S. F., D. A. Huri and S. H. Snyder (2005) Inducible nitricoxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2. Science. 310, 1966-1970.
22. Saccani, A., T. Schioppa, C. Porta, S. K. Biswas, M. Nebuloni, L. Vago, B. Bottazzi, M. P. Colombo, A. Mantovani and A. Sica (2006) p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responsesand antitumor resistance. Cancer Res. 66, 11432-11440.
23. Hao, N. B., M. H. Lu, Y. H. Fan, Y. L. Cao, Z. R. Zhang and S. M. Yang (2012) Macrophages in tumor microenvironmentsand the progression of tumors. Clin. Dev. Immunol. 2012, 948098-948108.
24. Mantovani, A., S. Sozzani, M. Locati, P. Allavena and A. Sica (2002) Macrophage polarization: tumor-associated macrophagesas a paradigm for polarized M2 mononuclearphagocytes. Trends Immunol. 23, 549-555.
25. Suganuma, H., J. W. Fahey, K. E. Bryan, Z. R. Healy and P. Talalay (2011) Stimulation of phagocytosis by sulforaphane. Biochem. Bioph. Res. Co. 405, 146-151.
26. Keller, R., R. Keist, A. Wechsler, T. P. Leist and P. H. Vandermeide (1990) Mechanisms of Macrophage-Mediated Tumor-Cell Killing-a Comparative-Analysis of the Roles of Reactive Nitrogen Intermediates and Tumor-Necrosis-Factor. Int J Cancer. 46, 682-686.
27. Yamanishi, T., T. Hatakeyama, K. Yamaguchi and T. Oda (2009) CEL-I, an N-Acetylgalactosamine (GalNAc)-Specific C-Type Lectin, Induces Nitric Oxide Production in RAW264.7 Mouse Macrophage Cell Line. J. Biochem. 146, 209-217.
28. Engin, A. B. (2011) Dual Function of Nitric Oxide in Carcinogenesis, Reappraisal. Curr. Drug. Metab. 12, 891-899.
29. Bogdan, C. and U. Schleicher (2006) Production of interferon-gamma by myeloid cells-fact or fancy? Trends Immunol. 27, 282-290.
30. Raschke, W. C., S. Baird, P. Ralph and I. Nakoinz (1978) Functional Macrophage Cell Lines Transformed by Abelson Leukemia-Virus. Cell. 15, 261-267.
31. Ando, K., N. Hunter and L. J. Peters (1979) Immunologically Nonspecific Enhancement of Artificial Lung Metastases in Tumor-Bearing Mice. Cancer Immunol. Immun. 6, 151-156.
32. Shirata, K., T. Suzuki, N. Yanaihara, K. Sugimoto and K. J. Mori (1991) Establishment of a Sarcoma Cell-Line, Ms-K, Expressing Ki-Ras Protooncogene Product from Mouse Bone-Marrow Stromal Cells. Biomed. Pharmacother. 45, 1-8.
33. Toda, K. I., K. Tsujioka, Y. Maruguchi, K. Ishii, Y. Miyachi, K. Kuribayashi and S. Imamura (1990) Establishment and Characterization of a Tumorigenic Murine Vascular Endothelial-Cell Line (F2). Cancer Res. 50, 5526-5530.
34. Zhong, X. Y., A. Yoshioka, Y. Mashio, T. Ikeda, H. Jiang, M. Touma, Q. Wu, C. Wang and K. Sugimoto (2011) Effect of vegfgene knockdown on growth of the murine sarcoma cell line MS-K. Genes Cells. 16, 625-638.