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Volumn 92, Issue 3, 2014, Pages 226-234

Myostatin inhibits proliferation and insulin-stimulated glucose uptake in mouse liver cells

Author keywords

Cell cycle; Glucose metabolism; Hepatogenesis; Malat1 siRNA; Myostatin

Indexed keywords

AMINO ACIDS; CELL PROLIFERATION; ENZYMES; GLUCOSE; INSULIN; MAMMALS; MUSCLE; PHOSPHORYLATION; POLYMERASE CHAIN REACTION;

EID: 84901982944     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/bcb-2014-0004     Document Type: Article
Times cited : (22)

References (49)
  • 1
    • 84877588756 scopus 로고    scopus 로고
    • Myostatin inhibits proliferation of human urethral rhabdosphincter satellite cells
    • 10.1111/j.1442-2042.2012.03186.x. 23050675.
    • Akita Y. Sumino Y. Mori K. Nomura T. Sato F. Mimata H. 2013. Myostatin inhibits proliferation of human urethral rhabdosphincter satellite cells. Int. J. Urol. 20 (5): 522-529. 10.1111/j.1442-2042.2012.03186.x. 23050675.
    • (2013) Int. J. Urol. , vol.20 , Issue.5 , pp. 522-529
    • Akita, Y.1    Sumino, Y.2    Mori, K.3    Nomura, T.4    Sato, F.5    Mimata, H.6
  • 2
    • 80052969358 scopus 로고    scopus 로고
    • Expression and function of myostatin in obesity, diabetes, and exercise adaptation
    • 10.1249/MSS.0b013e3182178bb4. 21364474.
    • Allen D.L. Hittel D.S. McPherron A.C. 2011. Expression and function of myostatin in obesity, diabetes, and exercise adaptation. Med. Sci. Sports Exerc. 43 (10): 1828-1835. 10.1249/MSS.0b013e3182178bb4. 21364474.
    • (2011) Med. Sci. Sports Exerc. , vol.43 , Issue.10 , pp. 1828-1835
    • Allen, D.L.1    Hittel, D.S.2    McPherron, A.C.3
  • 3
    • 36148969660 scopus 로고    scopus 로고
    • Myostatin regulates glucose uptake in BeWo cells
    • 10.1152/ajpendo.00331.2007. 17711997.
    • Antony N. Bass J.J. McMahon C.D. Mitchell M.D. 2007. Myostatin regulates glucose uptake in BeWo cells. Am. J. Physiol. Endocrinol. Metab. 293 (5): E1296-E1302. 10.1152/ajpendo.00331.2007. 17711997.
    • (2007) Am. J. Physiol. Endocrinol. Metab. , vol.293 , Issue.5
    • Antony, N.1    Bass, J.J.2    McMahon, C.D.3    Mitchell, M.D.4
  • 4
    • 84896292655 scopus 로고    scopus 로고
    • Myostatin induces insulin resistance via Cblb-mediated degradation of IRS1 in response to high calorie diet intake
    • 10.1074/jbc.M113.529925. 24451368.
    • Bonala S. Lokireddy S. McFarlane C. Patnam S. Sharma M. Kambadur R. 2014. Myostatin induces insulin resistance via Cblb-mediated degradation of IRS1 in response to high calorie diet intake. J. Biol. Chem. 289: 7654-7670. 10.1074/jbc.M113.529925. 24451368.
    • (2014) J. Biol. Chem. , vol.289 , pp. 7654-7670
    • Bonala, S.1    Lokireddy, S.2    McFarlane, C.3    Patnam, S.4    Sharma, M.5    Kambadur, R.6
  • 5
    • 84865709927 scopus 로고    scopus 로고
    • Activin B regulates islet composition and islet mass but not whole body glucose homeostasis or insulin sensitivity
    • 10.1152/ajpendo.00177.2012. 22739106.
    • Bonomi L. Brown M. Ungerleider N. Muse M. Matzuk M.M. Schneyer A. 2012. Activin B regulates islet composition and islet mass but not whole body glucose homeostasis or insulin sensitivity. Am. J. Physiol. Endocrinol. Metab. 303 (5): E587-E596. 10.1152/ajpendo.00177.2012. 22739106.
    • (2012) Am. J. Physiol. Endocrinol. Metab. , vol.303 , Issue.5
    • Bonomi, L.1    Brown, M.2    Ungerleider, N.3    Muse, M.4    Matzuk, M.M.5    Schneyer, A.6
  • 6
    • 0026644057 scopus 로고
    • Glucose-induced phosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) in isolated rat pancreatic islets
    • 1527003.
    • Calle R. Ganesan S. Smallwood J.I. Rasmussen H. 1992. Glucose-induced phosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) in isolated rat pancreatic islets. J. Biol. Chem. 267 (26): 18723-18727. 1527003.
    • (1992) J. Biol. Chem. , vol.267 , Issue.26 , pp. 18723-18727
    • Calle, R.1    Ganesan, S.2    Smallwood, J.I.3    Rasmussen, H.4
  • 7
    • 64149111913 scopus 로고    scopus 로고
    • Functional involvement of protein kinase C-betaII and its substrate, myristoylated alanine-rich C-kinase substrate (MARCKS), in insulin-stimulated glucose transport in L6 rat skeletal muscle cells
    • 10.1007/s00125-009-1298-7. 19252893.
    • Chappell D.S. Patel N.A. Jiang K. Li P. Watson J.E. Byers D.M. Cooper D.R. 2009. Functional involvement of protein kinase C-betaII and its substrate, myristoylated alanine-rich C-kinase substrate (MARCKS), in insulin-stimulated glucose transport in L6 rat skeletal muscle cells. Diabetologia, 52 (5): 901-911. 10.1007/s00125-009-1298-7. 19252893.
    • (2009) Diabetologia , vol.52 , Issue.5 , pp. 901-911
    • Chappell, D.S.1    Patel, N.A.2    Jiang, K.3    Li, P.4    Watson, J.E.5    Byers, D.M.6    Cooper, D.R.7
  • 8
    • 79958176329 scopus 로고    scopus 로고
    • Regulation of mammalian cell cycle progression in the regenerating liver
    • 10.1016/j.jtbi.2011.05.026. 21635899.
    • Chauhan A. Lorenzen S. Herzel H. Bernard S. 2011. Regulation of mammalian cell cycle progression in the regenerating liver. J. Theor. Biol. 283 (1): 103-112. 10.1016/j.jtbi.2011.05.026. 21635899.
    • (2011) J. Theor. Biol. , vol.283 , Issue.1 , pp. 103-112
    • Chauhan, A.1    Lorenzen, S.2    Herzel, H.3    Bernard, S.4
  • 9
    • 84904250528 scopus 로고    scopus 로고
    • A peptide that inhibits function of Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) reduces lung cancer metastasis
    • Chen, C.H. Thai, P. Yoneda, K. Adler, K.B. Yang, P.C. and Wu, R. 2013. In press. 10.1038/onc.2013.336. 23955080.
    • Chen, C.H., Thai, P., Yoneda, K., Adler, K.B., Yang, P.C., and Wu, R. 2013. A peptide that inhibits function of Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) reduces lung cancer metastasis. Oncogene. In press. 10.1038/onc.2013.336. 23955080.
    • Oncogene
  • 10
    • 0034465813 scopus 로고    scopus 로고
    • Activin A-induced HepG2 liver cell apoptosis: Involvement of activin receptors and Smad proteins
    • DOI 10.1210/en.141.3.1263
    • Chen W. Woodruff T.K. Mayo K.E. 2000. Activin A-induced HepG2 liver cell apoptosis: involvement of activin receptors and smad proteins. Endocrinology, 141 (3): 1263-1272. 10.1210/endo.141.3.7361. 10698204. (Pubitemid 32260471)
    • (2000) Endocrinology , vol.141 , Issue.3 , pp. 1263-1272
    • Chen, W.1    Woodruff, T.K.2    Mayo, K.E.3
  • 11
    • 78149282298 scopus 로고    scopus 로고
    • Myostatin regulates glucose metabolism via the AMP-activated protein kinase pathway in skeletal muscle cells
    • 10.1016/j.biocel.2010.09.017. 20887798.
    • Chen Y. Ye J. Cao L. Zhang Y. Xia W. Zhu D. 2010. Myostatin regulates glucose metabolism via the AMP-activated protein kinase pathway in skeletal muscle cells. Int. J. Biochem. Cell Biol. 42 (12): 2072-2081. 10.1016/j.biocel.2010.09.017. 20887798.
    • (2010) Int. J. Biochem. Cell Biol. , vol.42 , Issue.12 , pp. 2072-2081
    • Chen, Y.1    Ye, J.2    Cao, L.3    Zhang, Y.4    Xia, W.5    Zhu, D.6
  • 12
    • 84870866075 scopus 로고    scopus 로고
    • Consilience in sarcopenia of cirrhosis
    • 10.1007/s13539-012-0069-3. 22648736.
    • Dasarathy S. 2012. Consilience in sarcopenia of cirrhosis. J. Cachexia Sarcopenia Muscle, 3 (4): 225-237. 10.1007/s13539-012-0069-3. 22648736.
    • (2012) J. Cachexia Sarcopenia Muscle , vol.3 , Issue.4 , pp. 225-237
    • Dasarathy, S.1
  • 13
    • 79954640568 scopus 로고    scopus 로고
    • Sarcopenia associated with portosystemic shunting is reversed by follistatin
    • 10.1016/j.jhep.2010.08.032. 21145817.
    • Dasarathy S. McCullough A.J. Muc S. Schneyer A. Bennett C.D. Dodig M. Kalhan S.C. 2011. Sarcopenia associated with portosystemic shunting is reversed by follistatin. J. Hepatol. 54 (5): 915-921. 10.1016/j.jhep.2010.08.032. 21145817.
    • (2011) J. Hepatol. , vol.54 , Issue.5 , pp. 915-921
    • Dasarathy, S.1    McCullough, A.J.2    Muc, S.3    Schneyer, A.4    Bennett, C.D.5    Dodig, M.6    Kalhan, S.C.7
  • 15
    • 77956401570 scopus 로고    scopus 로고
    • Brief-reports: Elevated myostatin levels in patients with liver disease: A potential contributor to skeletal muscle wasting
    • 10.1213/ANE.0b013e3181eac1c9. 20686014.
    • Garcia P.S. Cabbabe A. Kambadur R. Nicholas G. Csete M. 2010. Brief-reports: elevated myostatin levels in patients with liver disease: a potential contributor to skeletal muscle wasting. Anesth. Analg. 111 (3): 707-709. 10.1213/ANE.0b013e3181eac1c9. 20686014.
    • (2010) Anesth. Analg. , vol.111 , Issue.3 , pp. 707-709
    • Garcia, P.S.1    Cabbabe, A.2    Kambadur, R.3    Nicholas, G.4    Csete, M.5
  • 16
    • 84880994574 scopus 로고    scopus 로고
    • AAV-Mediated Administration of Myostatin Pro-Peptide Mutant in Adult Ldlr Null Mice Reduces Diet-Induced Hepatosteatosis and Arteriosclerosis
    • 10.1371/journal.pone.0071017. 23936482.
    • Guo W. Wong S. Bhasin S. 2013. AAV-Mediated Administration of Myostatin Pro-Peptide Mutant in Adult Ldlr Null Mice Reduces Diet-Induced Hepatosteatosis and Arteriosclerosis. PloS One 8 (8): e71017. 10.1371/journal.pone.0071017. 23936482.
    • (2013) PloS One , vol.8 , Issue.8 , pp. 71017
    • Guo, W.1    Wong, S.2    Bhasin, S.3
  • 17
    • 84871973062 scopus 로고    scopus 로고
    • Inducing cell proliferation inhibition, apoptosis, and motility reduction by silencing long noncoding ribonucleic acid metastasis-associated lung adenocarcinoma transcript 1 in urothelial carcinoma of the bladder
    • 209. 10.1016/j.urology.2012.08.044. 23153939.
    • Han Y. Liu Y. Nie L. Gui Y. Cai Z. 2013. Inducing cell proliferation inhibition, apoptosis, and motility reduction by silencing long noncoding ribonucleic acid metastasis-associated lung adenocarcinoma transcript 1 in urothelial carcinoma of the bladder. Urology, 81 (1): 209 e201-e207. 10.1016/j.urology.2012.08.044. 23153939.
    • (2013) Urology, 81 (1)
    • Han, Y.1    Liu, Y.2    Nie, L.3    Gui, Y.4    Cai, Z.5
  • 18
    • 78649677085 scopus 로고    scopus 로고
    • Transcriptional regulation of energy metabolism in the liver
    • 10.3109/10799893.2010.509730. 20735177.
    • Hirota K. Fukamizu A. 2010. Transcriptional regulation of energy metabolism in the liver. J. Recept. Signal Transduct. Res. 30 (6): 403-409. 10.3109/10799893.2010.509730. 20735177.
    • (2010) J. Recept. Signal Transduct. Res. , vol.30 , Issue.6 , pp. 403-409
    • Hirota, K.1    Fukamizu, A.2
  • 19
    • 63249100559 scopus 로고    scopus 로고
    • Increased secretion and expression of myostatin in skeletal muscle from extremely obese women
    • 10.2337/db08-0943. 18835929.
    • Hittel D.S. Berggren J.R. Shearer J. Boyle K. Houmard J.A. 2009. Increased secretion and expression of myostatin in skeletal muscle from extremely obese women. Diabetes, 58 (1): 30-38. 10.2337/db08-0943. 18835929.
    • (2009) Diabetes , vol.58 , Issue.1 , pp. 30-38
    • Hittel, D.S.1    Berggren, J.R.2    Shearer, J.3    Boyle, K.4    Houmard, J.A.5
  • 20
    • 78049527383 scopus 로고    scopus 로고
    • Myostatin decreases with aerobic exercise and associates with insulin resistance
    • 10.1249/MSS.0b013e3181e0b9a8. 20386333.
    • Hittel D.S. Axelson M. Sarna N. Shearer J. Huffman K.M. Kraus W.E. 2010. Myostatin decreases with aerobic exercise and associates with insulin resistance. Med. Sci. Sports Exerc. 42 (11): 2023-2029. 10.1249/MSS. 0b013e3181e0b9a8. 20386333.
    • (2010) Med. Sci. Sports Exerc. , vol.42 , Issue.11 , pp. 2023-2029
    • Hittel, D.S.1    Axelson, M.2    Sarna, N.3    Shearer, J.4    Huffman, K.M.5    Kraus, W.E.6
  • 21
    • 80052973749 scopus 로고    scopus 로고
    • Analysis of myostatin and its related factors in various porcine tissues
    • 10.2527/jas.2010-3827. 21571901.
    • Jiao J. Yuan T. Zhou Y. Xie W. Zhao Y. Zhao J. et al 2011. Analysis of myostatin and its related factors in various porcine tissues. J. Anim. Sci. 89 (10): 3099-3106. 10.2527/jas.2010-3827. 21571901.
    • (2011) J. Anim. Sci. , vol.89 , Issue.10 , pp. 3099-3106
    • Jiao, J.1    Yuan, T.2    Zhou, Y.3    Xie, W.4    Zhao, Y.5    Zhao, J.6
  • 22
    • 0038636430 scopus 로고    scopus 로고
    • Mechanisms involved in the inhibition of myoblast proliferation and differentiation by myostatin
    • DOI 10.1016/S0014-4827(03)00074-0
    • Joulia D. Bernardi H. Garandel V. Rabenoelina F. Vernus B. Cabello G. 2003. Mechanisms involved in the inhibition of myoblast proliferation and differentiation by myostatin. Exp. Cell Res. 286 (2): 263-275. 10.1016/S0014-4827(03)00074-0. 12749855. (Pubitemid 36566439)
    • (2003) Experimental Cell Research , vol.286 , Issue.2 , pp. 263-275
    • Joulia, D.1    Bernardi, H.2    Garandel, V.3    Rabenoelina, F.4    Vernus, B.5    Cabello, G.6
  • 23
    • 2442658168 scopus 로고    scopus 로고
    • IGF-I/IGFBP-3 ameliorates alterations in protein synthesis, eIF4E availability, and myostatin in alcohol-fed rats
    • 10.1152/ajpendo.00554.2003. 14749210.
    • Lang C.H. Frost R.A. Svanberg E. Vary T.C. 2004. IGF-I/IGFBP-3 ameliorates alterations in protein synthesis, eIF4E availability, and myostatin in alcohol-fed rats. Am. J. Physiol. Endocrinol. Metab. 286 (6): E916-E926. 10.1152/ajpendo.00554.2003. 14749210.
    • (2004) Am. J. Physiol. Endocrinol. Metab. , vol.286 , Issue.6
    • Lang, C.H.1    Frost, R.A.2    Svanberg, E.3    Vary, T.C.4
  • 24
    • 38849112545 scopus 로고    scopus 로고
    • The E1 ubiquitin-activating enzyme Uba1 in Drosophila controls apoptosis autonomously and tissue growth non-autonomously
    • DOI 10.1242/dev.011288
    • Lee T.V. Ding T. Chen Z. Rajendran V. Scherr H. Lackey M. et al 2008. The E1 ubiquitin-activating enzyme Uba1 in Drosophila controls apoptosis autonomously and tissue growth non-autonomously. Development, 135 (1): 43-52. 10.1242/dev.011288. 18045837. (Pubitemid 351201480)
    • (2008) Development , vol.135 , Issue.1 , pp. 43-52
    • Lee, T.V.1    Ding, T.2    Chen, Z.3    Rajendran, V.4    Scherr, H.5    Lackey, M.6    Bolduc, C.7    Bergmann, A.8
  • 25
    • 0032015044 scopus 로고    scopus 로고
    • Abnormalities of Liver Regeneration: A Review
    • Leevy C.B. 1998. Abnormalities of liver regeneration: a review. Dig. Dis. 16 (2): 88-98. 10.1159/000016852. 9571374. (Pubitemid 128530657)
    • (1998) Digestive Diseases , vol.16 , Issue.2 , pp. 88-98
    • Leevy, C.B.1
  • 26
    • 79951580425 scopus 로고    scopus 로고
    • Control of RNA processing by a large non-coding RNA over-expressed in carcinomas
    • 10.1016/j.febslet.2011.01.030. 21266177.
    • Lin R. Roychowdhury-Saha M. Black C. Watt A.T. Marcusson E.G. Freier S.M. Edgington T.S. 2011. Control of RNA processing by a large non-coding RNA over-expressed in carcinomas. FEBS Lett. 585 (4): 671-676. 10.1016/j.febslet. 2011.01.030. 21266177.
    • (2011) FEBS Lett. , vol.585 , Issue.4 , pp. 671-676
    • Lin, R.1    Roychowdhury-Saha, M.2    Black, C.3    Watt, A.T.4    Marcusson, E.G.5    Freier, S.M.6    Edgington, T.S.7
  • 28
    • 0141768237 scopus 로고    scopus 로고
    • Myostatin negatively regulates satellite cell activation and self-renewal
    • DOI 10.1083/jcb.200207056
    • McCroskery S. Thomas M. Maxwell L. Sharma M. Kambadur R. 2003. Myostatin negatively regulates satellite cell activation and self-renewal. J. Cell Biol. 162 (6): 1135-1147. 10.1083/jcb.200207056. 12963705. (Pubitemid 37174195)
    • (2003) Journal of Cell Biology , vol.162 , Issue.6 , pp. 1135-1147
    • McCroskery, S.1    Thomas, M.2    Maxwell, L.3    Sharma, M.4    Kambadur, R.5
  • 31
    • 0036200822 scopus 로고    scopus 로고
    • Suppression of body fat accumulation in myostatin-deficient mice
    • DOI 10.1172/JCI200213562
    • McPherron A.C. Lee S.J. 2002. Suppression of body fat accumulation in myostatin-deficient mice. J. Clin. Invest. 109 (5): 595-601. 10.1172/JCI13562. 11877467. (Pubitemid 34204838)
    • (2002) Journal of Clinical Investigation , vol.109 , Issue.5 , pp. 595-601
    • McPherron, A.C.1    Lee, S.-J.2
  • 32
    • 84902005289 scopus 로고    scopus 로고
    • Establishing Genomic/Transcriptomic Links between Alzheimers Disease and Type II Diabetes Mellitus by Meta-Analysis Approach. CNS Neurol
    • Mirza, Z. Kamal, M.A. Abuzenadah, A.M. Al-Qahtani, M.H. and Karim, S. 2013. 24059308.
    • Mirza, Z., Kamal, M.A., Abuzenadah, A.M., Al-Qahtani, M.H., and Karim, S. 2013. Establishing Genomic/Transcriptomic Links between Alzheimers Disease and Type II Diabetes Mellitus by Meta-Analysis Approach. CNS Neurol. Disord. Drug Targets. 24059308.
    • Disord. Drug Targets
  • 33
    • 33646074341 scopus 로고    scopus 로고
    • Myostatin is a human placental product that regulates glucose uptake
    • 10.1210/jc.2005-2361. 16464946.
    • Mitchell M.D. Osepchook C.C. Leung K.C. McMahon C.D. Bass J.J. 2006. Myostatin is a human placental product that regulates glucose uptake. J. Clin. Endocrinol. Metab. 91 (4): 1434-1437. 10.1210/jc.2005-2361. 16464946.
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , Issue.4 , pp. 1434-1437
    • Mitchell, M.D.1    Osepchook, C.C.2    Leung, K.C.3    McMahon, C.D.4    Bass, J.J.5
  • 34
    • 70450193472 scopus 로고    scopus 로고
    • Human genetics illuminates the paths to metabolic disease
    • 10.1038/nature08532. 19924209.
    • ORahilly S. 2009. Human genetics illuminates the paths to metabolic disease. Nature, 462 (7271): 307-314. 10.1038/nature08532. 19924209.
    • (2009) Nature , vol.462 , Issue.7271 , pp. 307-314
    • Orahilly, S.1
  • 35
    • 84864283300 scopus 로고    scopus 로고
    • Muscles, exercise and obesity: Skeletal muscle as a secretory organ
    • 10.1038/nrendo.2012.49. 22473333.
    • Pedersen B.K. Febbraio M.A. 2012. Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat. Rev. Endocrinol. 8 (8): 457-465. 10.1038/nrendo.2012.49. 22473333.
    • (2012) Nat. Rev. Endocrinol. , vol.8 , Issue.8 , pp. 457-465
    • Pedersen, B.K.1    Febbraio, M.A.2
  • 36
    • 84881016307 scopus 로고    scopus 로고
    • Muscle-to-organ cross talk mediated by myokines
    • 10.4161/adip.20344. 23700527.
    • Pedersen L. Hojman P. 2012. Muscle-to-organ cross talk mediated by myokines. Adipocyte, 1 (3): 164-167. 10.4161/adip.20344. 23700527.
    • (2012) Adipocyte , vol.1 , Issue.3 , pp. 164-167
    • Pedersen, L.1    Hojman, P.2
  • 38
    • 2542422838 scopus 로고    scopus 로고
    • Differential response to exogenous and endogenous myostatin in myoblasts suggest that myostatin acts as an autocrine factor in vivo
    • DOI 10.1210/en.2003-1166
    • Rios R. Fernandez-Nocelos S. Carneiro I. Arce V.M. Devesa J. 2004. Differential response to exogenous and endogenous myostatin in myoblasts suggests that myostatin acts as an autocrine factor in vivo. Endocrinology, 145 (6): 2795-2803. 10.1210/en.2003-1166. 14976141. (Pubitemid 38686229)
    • (2004) Endocrinology , vol.145 , Issue.6 , pp. 2795-2803
    • Rios, R.1    Fernandez-Nocelos, S.2    Carneiro, I.3    Arce, V.M.4    Devesa, J.5
  • 39
    • 81755161347 scopus 로고    scopus 로고
    • The long noncoding MALAT-1 RNA indicates a poor prognosis in non-small cell lung cancer and induces migration and tumor growth
    • 10.1097/JTO.0b013e3182307eac. 22088988.
    • Schmidt L.H. Spieker T. Koschmieder S. Schaffers S. Humberg J. Jungen D. et al 2011. The long noncoding MALAT-1 RNA indicates a poor prognosis in non-small cell lung cancer and induces migration and tumor growth. J. Thorac. Oncol. 6 (12): 1984-1992. 10.1097/JTO.0b013e3182307eac. 22088988.
    • (2011) J. Thorac. Oncol. , vol.6 , Issue.12 , pp. 1984-1992
    • Schmidt, L.H.1    Spieker, T.2    Koschmieder, S.3    Schaffers, S.4    Humberg, J.5    Jungen, D.6
  • 40
    • 34547092153 scopus 로고    scopus 로고
    • Antagonism of myostatin enhances muscle regeneration during sarcopenia
    • DOI 10.1038/sj.mt.6300182, PII 6300182
    • Siriett V. Salerno M.S. Berry C. Nicholas G. Bower R. Kambadur R. Sharma M. 2007. Antagonism of myostatin enhances muscle regeneration during sarcopenia. Mol. Ther. 15 (8): 1463-1470. 10.1038/sj.mt.6300182. 17551508. (Pubitemid 47099303)
    • (2007) Molecular Therapy , vol.15 , Issue.8 , pp. 1463-1470
    • Siriett, V.1    Salerno, M.S.2    Berry, C.3    Nicholas, G.4    Bower, R.5    Kambadur, R.6    Sharma, M.7
  • 42
    • 0034704106 scopus 로고    scopus 로고
    • Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation
    • DOI 10.1074/jbc.M004356200
    • Thomas M. Langley B. Berry C. Sharma M. Kirk S. Bass J. Kambadur R. 2000. Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation. J. Biol. Chem. 275 (51): 40235-40243. 10.1074/jbc.M004356200. 10976104. (Pubitemid 32064654)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.51 , pp. 40235-40243
    • Thomas, M.1    Langley, B.2    Berry, C.3    Sharma, M.4    Kirk, S.5    Bass, J.6    Kambadur, R.7
  • 43
    • 84865634036 scopus 로고    scopus 로고
    • Increased circulating myostatin in patients with type 2 diabetes mellitus
    • 10.1007/s11596-012-0092-9. 22886966.
    • Wang F. Liao Y. Li X. Ren C. Cheng C. Ren Y. 2012. Increased circulating myostatin in patients with type 2 diabetes mellitus. J. Huazhong Univ. Sci. Technol. Med. Sci. 32 (4): 534-539. 10.1007/s11596-012-0092-9. 22886966.
    • (2012) J. Huazhong Univ. Sci. Technol. Med. Sci. , vol.32 , Issue.4 , pp. 534-539
    • Wang, F.1    Liao, Y.2    Li, X.3    Ren, C.4    Cheng, C.5    Ren, Y.6
  • 44
    • 84878667238 scopus 로고    scopus 로고
    • Myostatin-induced inhibition of the long noncoding RNA Malat1 is associated with decreased myogenesis
    • 10.1152/ajpcell.00392.2012. 23485710.
    • Watts R. Johnsen V.L. Shearer J. Hittel D.S. 2013. Myostatin-induced inhibition of the long noncoding RNA Malat1 is associated with decreased myogenesis. Am. J. Physiol. Cell Physiol. 304 (10): C995-C1001. 10.1152/ajpcell.00392.2012. 23485710.
    • (2013) Am. J. Physiol. Cell Physiol. , vol.304 , Issue.10
    • Watts, R.1    Johnsen, V.L.2    Shearer, J.3    Hittel, D.S.4
  • 45
    • 65549149871 scopus 로고    scopus 로고
    • Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance
    • 10.2337/db08-0245. 19208906.
    • Wilkes J.J. Lloyd D.J. Gekakis N. 2009. Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance. Diabetes, 58 (5): 1133-1143. 10.2337/db08-0245. 19208906.
    • (2009) Diabetes , vol.58 , Issue.5 , pp. 1133-1143
    • Wilkes, J.J.1    Lloyd, D.J.2    Gekakis, N.3
  • 46
    • 33947538814 scopus 로고    scopus 로고
    • Myostatin induces cyclin D1 degradation to cause cell cycle arrest through a phosphatidylinositol 3-kinase/AKT/GSK-3β pathway and is antagonized by insulin-like growth factor
    • DOI 10.1074/jbc.M610185200
    • Yang W. Zhang Y. Li Y. Wu Z. Zhu D. 2007. Myostatin induces cyclin D1 degradation to cause cell cycle arrest through a phosphatidylinositol 3-kinase/AKT/GSK-3 beta pathway and is antagonized by insulin-like growth factor 1. J. Biol. Chem. 282 (6): 3799-3808. 10.1074/jbc.M610185200. 17130121. (Pubitemid 47084479)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.6 , pp. 3799-3808
    • Yang, W.1    Zhang, Y.2    Li, Y.3    Wu, Z.4    Zhu, D.5
  • 47
    • 80052536289 scopus 로고    scopus 로고
    • Myostatin-deficient mice exhibit reduced insulin resistance through activating the AMP-activated protein kinase signalling pathway
    • 10.1007/s00125-011-2079-7. 21347623.
    • Zhang C. McFarlane C. Lokireddy S. Bonala S. Ge X. Masuda S. et al 2011. Myostatin-deficient mice exhibit reduced insulin resistance through activating the AMP-activated protein kinase signalling pathway. Diabetologia, 54 (6): 1491-1501. 10.1007/s00125-011-2079-7. 21347623.
    • (2011) Diabetologia , vol.54 , Issue.6 , pp. 1491-1501
    • Zhang, C.1    McFarlane, C.2    Lokireddy, S.3    Bonala, S.4    Ge, X.5    Masuda, S.6
  • 48
    • 84856725443 scopus 로고    scopus 로고
    • Inhibition of myostatin protects against diet-induced obesity by enhancing fatty acid oxidation and promoting a brown adipose phenotype in mice
    • 10.1007/s00125-011-2304-4. 21927895.
    • Zhang C. McFarlane C. Lokireddy S. Masuda S. Ge X. Gluckman P.D. et al 2012. Inhibition of myostatin protects against diet-induced obesity by enhancing fatty acid oxidation and promoting a brown adipose phenotype in mice. Diabetologia, 55 (1): 183-193. 10.1007/s00125-011-2304-4. 21927895.
    • (2012) Diabetologia , vol.55 , Issue.1 , pp. 183-193
    • Zhang, C.1    McFarlane, C.2    Lokireddy, S.3    Masuda, S.4    Ge, X.5    Gluckman, P.D.6


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