A short term quality control tool for biodegradable microspheres

AAPS PharmSciTech

Volumn 15, Issue 3, 2014, Pages 530-541

  D'Souza, Susan ^a,b   Faraj, Jabar A ^a,c   Dorati, Rossella ^a,d   DeLuca, Patrick P ^a  

^a University of Kentucky   (United States)

^b DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^c Fresenius Kabi USA ^*  (United States)

^d UNIVERSITY OF PAVIA   (Italy)

Author keywords

accelerated in vitro release; biodegradable microspheres; modified Weibull equation (MWE); QC tool

Indexed keywords

LEUPRORELIN; MICROSPHERE; PEPTIDE; POLYGLACTIN; POLYMER; DRUG CARRIER; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; WATER;

ARTICLE; BIODEGRADABILITY; DATA ANALYSIS; DEGRADATION; DRUG FORMULATION; DRUG RELEASE; EVAPORATION; HYDRATION; IN VITRO STUDY; MATHEMATICAL MODEL; MODIFIED WEIBULL EQUATION; PARTICLE SIZE; PRIORITY JOURNAL; QUALITY CONTROL; REPRODUCIBILITY; SOLVENT EXTRACTION; SURFACE PROPERTY; CHEMICAL MODEL; CHEMISTRY; COMPARATIVE STUDY; KINETICS; MEDICINAL CHEMISTRY; PHARMACEUTICS; POROSITY; PROCEDURES; SOLUBILITY; STANDARDS; STATISTICAL MODEL;

CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; KINETICS; LACTIC ACID; LEUPROLIDE; MICROSPHERES; MODELS, CHEMICAL; MODELS, STATISTICAL; PARTICLE SIZE; POLYGLYCOLIC ACID; POROSITY; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; SOLUBILITY; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL; WATER;

EID: 84901978844     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-013-0052-0     Document Type: Article

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