메뉴 건너뛰기




Volumn 24, Issue 6, 2014, Pages 742-761

CKIP-1 regulates macrophage proliferation by inhibiting TRAF6-mediated Akt activation

Author keywords

Akt signaling; CKIP 1; GSK3 ; macrophage proliferation; TRAF6

Indexed keywords

CARRIER PROTEIN; CKIP-1 PROTEIN, MOUSE; COLONY STIMULATING FACTOR 1; CYCLIN D; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

EID: 84901845351     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2014.53     Document Type: Article
Times cited : (65)

References (54)
  • 1
    • 67650485985 scopus 로고    scopus 로고
    • Alternative activation of macrophages: An immunologic functional perspective
    • Martinez FO, Helming L, Gordon S. Alternative activation of macrophages: an immunologic functional perspective. Annu Rev Immunol 2009; 27:451-483.
    • (2009) Annu Rev Immunol , vol.27 , pp. 451-483
    • Martinez, F.O.1    Helming, L.2    Gordon, S.3
  • 2
    • 46249090513 scopus 로고    scopus 로고
    • Colony-stimulating factors in inflammation and autoimmunity
    • DOI 10.1038/nri2356, PII NRI2356
    • Hamilton JA. Colony-stimulating factors in inflammation and autoimmunity. Nat Rev Immunol 2008; 8:533-544. (Pubitemid 351913679)
    • (2008) Nature Reviews Immunology , vol.8 , Issue.7 , pp. 533-544
    • Hamilton, J.A.1
  • 3
    • 30044448462 scopus 로고    scopus 로고
    • Colony-stimulating factor-1 in immunity and inflammation
    • DOI 10.1016/j.coi.2005.11.006, PII S0952791505001974, Innate Immunity/Antigen Processing and Recognition
    • Chitu V, Stanley ER. Colony-stimulating factor-1 in immunity and inflammation. Curr Opin Immunol 2006; 18:39-48. (Pubitemid 43049646)
    • (2006) Current Opinion in Immunology , vol.18 , Issue.1 , pp. 39-48
    • Chitu, V.1    Stanley, E.R.2
  • 5
    • 0026640616 scopus 로고
    • CSF-1 deficiency in the op/op mouse has differential effects on macrophage populations and differentiation stages
    • Wiktor-Jedrzejczak W, Ratajczak MZ, Ptasznik A, Sell KW, Ahmed-Ansari A, Ostertag W. CSF-1 deficiency in the op/op mouse has differential effects on macrophage populations and differentiation stages. Exp Hematol 1992; 20:1004-1010.
    • (1992) Exp Hematol , vol.20 , pp. 1004-1010
    • Wiktor-Jedrzejczak, W.1    Ratajczak, M.Z.2    Ptasznik, A.3    Sell, K.W.4    Ahmed-Ansari, A.5    Ostertag, W.6
  • 7
    • 7444254061 scopus 로고    scopus 로고
    • CSF-1 regulation of the wandering macrophage: Complexity in action
    • DOI 10.1016/j.tcb.2004.09.016, PII S0962892404002673
    • Pixley FJ, Stanley ER. CSF-1 regulation of the wandering macrophage: complexity in action. Trends Cell Biol 2004; 14:628-638. (Pubitemid 39440612)
    • (2004) Trends in Cell Biology , vol.14 , Issue.11 , pp. 628-638
    • Pixley, F.J.1    Stanley, E.R.2
  • 8
    • 33749611445 scopus 로고    scopus 로고
    • Colony-stimulating factor-1 requires PI3-kinase-mediated metabolism for proliferation and survival in myeloid cells
    • DOI 10.1038/sj.cdd.4401884, PII 4401884
    • Lee AW, States DJ. Colony-stimulating factor-1 requires PI3- kinase-mediated metabolism for proliferation and survival in myeloid cells. Cell Death Differ 2006; 13:1900-1914. (Pubitemid 44542403)
    • (2006) Cell Death and Differentiation , vol.13 , Issue.11 , pp. 1900-1914
    • Lee, A.W.-M.1    States, D.J.2
  • 9
    • 0033782189 scopus 로고    scopus 로고
    • Ets-2 is a target for an akt (protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice
    • Smith JL, Schaffner AE, Hofmeister JK, et al. ets-2 is a target for an akt (protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice. Mol Cell Biol 2000; 20:8026-8034.
    • (2000) Mol Cell Biol , vol.20 , pp. 8026-8034
    • Smith, J.L.1    Schaffner, A.E.2    Hofmeister, J.K.3
  • 10
    • 0033556255 scopus 로고    scopus 로고
    • Synergistic activation of mitogen-activated protein kinase by cyclic AMP and myeloid growth factors opposes cyclic AMP's growth-inhibitory effects
    • Lee AW. Synergistic activation of mitogen-activated protein kinase by cyclic AMP and myeloid growth factors opposes cyclic AMP's growth-inhibitory effects. Blood 1999; 93:537-553. (Pubitemid 29035735)
    • (1999) Blood , vol.93 , Issue.2 , pp. 537-553
    • Lee, A.W.-M.1
  • 11
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB Signaling: Navigating Downstream
    • DOI 10.1016/j.cell.2007.06.009, PII S0092867407007751
    • Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream. Cell 2007; 129:1261-1274. (Pubitemid 46962095)
    • (2007) Cell , vol.129 , Issue.7 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 12
    • 0024372679 scopus 로고
    • The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase
    • DOI 10.1038/342699a0
    • Varticovski L, Druker B, Morrison D, Cantley L, Roberts T. The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase. Nature 1989; 342:699-702. (Pubitemid 20001589)
    • (1989) Nature , vol.342 , Issue.6250 , pp. 699-702
    • Varticovski, L.1    Druker, B.2    Morrison, D.3    Cantley, L.4    Roberts, T.5
  • 13
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta SR, Brunet A, Greenberg ME. Cellular survival: a play in three Akts. Genes Dev 1999; 13:2905-2927.
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 14
    • 79958099799 scopus 로고    scopus 로고
    • Phosphorylation of CSF-1R Y721 mediates its association with PI3K to regulate macrophage motility and enhancement of tumor cell invasion
    • Sampaio NG, Yu W, Cox D, et al. Phosphorylation of CSF-1R Y721 mediates its association with PI3K to regulate macrophage motility and enhancement of tumor cell invasion. J Cell Sci 2011; 124:2021-2031.
    • (2011) J Cell Sci , vol.124 , pp. 2021-2031
    • Sampaio, N.G.1    Yu, W.2    Cox, D.3
  • 15
    • 67649205726 scopus 로고    scopus 로고
    • Macrophage colonystimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and betacatenin
    • Otero K, Turnbull IR, Poliani PL, et al. Macrophage colonystimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and betacatenin. Nat Immunol 2009; 10:734-743.
    • (2009) Nat Immunol , vol.10 , pp. 734-743
    • Otero, K.1    Turnbull, I.R.2    Poliani, P.L.3
  • 16
    • 20144367088 scopus 로고    scopus 로고
    • Role for the pleckstrin homology domain-containing protein CKIP-1 in AP-1 regulation and apoptosis
    • DOI 10.1038/sj.emboj.7600532
    • Zhang L, Xing G, Tie Y, et al. Role for the pleckstrin homology domain-containing protein CKIP-1 in AP-1 regulation and apoptosis. EMBO J 2005; 24:766-778. (Pubitemid 40396106)
    • (2005) EMBO Journal , vol.24 , Issue.4 , pp. 766-778
    • Zhang, L.1    Xing, G.2    Tie, Y.3    Tang, Y.4    Tian, C.5    Li, L.6    Sun, L.7    Wei, H.8    Zhu, Y.9    He, F.10
  • 17
    • 0034640476 scopus 로고    scopus 로고
    • Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2
    • DOI 10.1074/jbc.275.19.14295
    • Bosc DG, Graham KC, Saulnier RB, et al. Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2. J Biol Chem 2000; 275:14295-14306. (Pubitemid 30339711)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.19 , pp. 14295-14306
    • Bosc, D.G.1    Graham, K.C.2    Saulnier, R.B.3    Zhang, C.4    Prober, D.5    Gietz, R.D.6    Litchfield, D.W.7
  • 19
    • 17644371009 scopus 로고    scopus 로고
    • The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein
    • DOI 10.1128/MCB.25.9.3519-3534.2005
    • Canton DA, Olsten ME, Kim K, et al. The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein. Mol Cell Biol 2005; 25:3519-3534. (Pubitemid 40559559)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.9 , pp. 3519-3534
    • Canton, D.A.1    Olsten, M.E.K.2    Kim, K.3    Doherty-Kirby, A.4    Lajoie, G.5    Cooper, J.A.6    Litchfield, D.W.7
  • 20
    • 84867474747 scopus 로고    scopus 로고
    • CKIP-1: A scaffold protein and potential therapeutic target integrating multiple signaling pathways and physiological functions
    • Nie J, Liu L, He F, Fu X, Han W, Zhang L. CKIP-1: a scaffold protein and potential therapeutic target integrating multiple signaling pathways and physiological functions. Ageing Res Rev 2013; 12:276-281.
    • (2013) Ageing Res Rev , vol.12 , pp. 276-281
    • Nie, J.1    Liu, L.2    He, F.3    Fu, X.4    Han, W.5    Zhang, L.6
  • 21
    • 48649104139 scopus 로고    scopus 로고
    • Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1
    • Lu K, Yin X, Weng T, et al. Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1. Nat Cell Biol 2008; 10:994-1002.
    • (2008) Nat Cell Biol , vol.10 , pp. 994-1002
    • Lu, K.1    Yin, X.2    Weng, T.3
  • 22
    • 84871334776 scopus 로고    scopus 로고
    • CKIP-1 inhibits cardiac hypertrophy by regulating class II histone deacetylase phosphorylation through recruiting PP2A
    • Ling S, Sun Q, Li Y, et al. CKIP-1 inhibits cardiac hypertrophy by regulating class II histone deacetylase phosphorylation through recruiting PP2A. Circulation 2012; 126:3028-3040.
    • (2012) Circulation , vol.126 , pp. 3028-3040
    • Ling, S.1    Sun, Q.2    Li, Y.3
  • 23
    • 33947259324 scopus 로고    scopus 로고
    • The PH domain containing protein CKIP-1 binds to IFP35 and Nmi and is involved in cytokine signaling
    • DOI 10.1016/j.cellsig.2006.11.002, PII S0898656806002968
    • Zhang L, Tang Y, Tie Y, et al. The PH domain containing protein CKIP-1 binds to IFP35 and Nmi and is involved in cytokine signaling. Cell Signal 2007; 19:932-944. (Pubitemid 46436434)
    • (2007) Cellular Signalling , vol.19 , Issue.5 , pp. 932-944
    • Zhang, L.1    Tang, Y.2    Tie, Y.3    Tian, C.4    Wang, J.5    Dong, Y.6    Sun, Z.7    He, F.8
  • 24
    • 84877804872 scopus 로고    scopus 로고
    • Casein kinase 2-interacting protein-1, an inflammatory signaling molecule interferes with TNF reverse signaling in human model cells
    • Juhasz K, Zvara A, Lipp AM, et al. Casein kinase 2-interacting protein-1, an inflammatory signaling molecule interferes with TNF reverse signaling in human model cells. Immunol Lett 2013; 152:55-64.
    • (2013) Immunol Lett , vol.152 , pp. 55-64
    • Juhasz, K.1    Zvara, A.2    Lipp, A.M.3
  • 26
    • 69549116880 scopus 로고    scopus 로고
    • The E3 ligase TRAF6 regulates Akt ubiquitination and activation
    • Yang WL, Wang J, Chan CH, et al. The E3 ligase TRAF6 regulates Akt ubiquitination and activation. Science 2009; 325:1134-1138.
    • (2009) Science , vol.325 , pp. 1134-1138
    • Yang, W.L.1    Wang, J.2    Chan, C.H.3
  • 29
    • 35448935143 scopus 로고    scopus 로고
    • Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo
    • DOI 10.1158/0008-5472.CAN-07-1050
    • Tokuda E, Fujita N, Oh-hara T, et al. Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domaininteracting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo. Cancer Res 2007; 67:9666-9676. (Pubitemid 47621213)
    • (2007) Cancer Research , vol.67 , Issue.20 , pp. 9666-9676
    • Tokuda, E.1    Fujita, N.2    Oh-hara, T.3    Sato, S.4    Kurata, A.5    Katayama, R.6    Itoh, T.7    Takenawa, T.8    Miyazono, K.9    Tsuruo, T.10
  • 30
    • 31344463886 scopus 로고    scopus 로고
    • Association of β-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling
    • DOI 10.1038/ni1294, PII N1294
    • Wang Y, Tang Y, Teng L, Wu Y, Zhao X, Pei G. Association of beta-arrestin and TRAF6 negatively regulates toll-like receptor-interleukin 1 receptor signaling. Nat Immunol 2006; 7:139-147. (Pubitemid 43135879)
    • (2006) Nature Immunology , vol.7 , Issue.2 , pp. 139-147
    • Wang, Y.1    Tang, Y.2    Teng, L.3    Wu, Y.4    Zhao, X.5    Pei, G.6
  • 31
    • 67650724069 scopus 로고    scopus 로고
    • Regulation and function of NFkappaB transcription factors in the immune system
    • Vallabhapurapu S, Karin M. Regulation and function of NFkappaB transcription factors in the immune system. Annu Rev Immunol 2009; 27:693-733.
    • (2009) Annu Rev Immunol , vol.27 , pp. 693-733
    • Vallabhapurapu, S.1    Karin, M.2
  • 32
    • 0034459567 scopus 로고    scopus 로고
    • Macrophages require constitutive NF-κB activation to maintain A1 expression and mitochondrial homeostasis
    • DOI 10.1128/MCB.20.23.8855-8865.2000
    • Pagliari LJ, Perlman H, Liu H, Pope RM. Macrophages require constitutive NF-kappaB activation to maintain A1 expression and mitochondrial homeostasis. Mol Cell Biol 2000; 20:8855-8865. (Pubitemid 32245918)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.23 , pp. 8855-8865
    • Pagliari, L.J.1    Perlman, H.2    Liu, H.3    Pope, R.M.4
  • 33
    • 84055207488 scopus 로고    scopus 로고
    • M-CSF induces monocyte survival by activating NF-kappaB p65 phosphorylation at Ser276 via protein kinase C
    • Wang Y, Mo X, Piper MG, et al. M-CSF induces monocyte survival by activating NF-kappaB p65 phosphorylation at Ser276 via protein kinase C. PLoS One 2011; 6:e28081.
    • (2011) PLoS One , vol.6
    • Wang, Y.1    Mo, X.2    Piper, M.G.3
  • 34
    • 80054716826 scopus 로고    scopus 로고
    • The role of atypical protein kinase C in CSF-1-dependent Erk activation and proliferation in myeloid progenitors and macrophages
    • Lee AW. The role of atypical protein kinase C in CSF-1-dependent Erk activation and proliferation in myeloid progenitors and macrophages. PLoS One 2011; 6:e25580.
    • (2011) PLoS One , vol.6
    • Lee, A.W.1
  • 36
    • 33846948594 scopus 로고    scopus 로고
    • Recruitment of insulin receptor substrate-1 and activation of NF-kappaB essential for midkine growth signaling through anaplastic lymphoma kinase
    • Kuo AH, Stoica GE, Riegel AT, Wellstein A. Recruitment of insulin receptor substrate-1 and activation of NF-kappaB essential for midkine growth signaling through anaplastic lymphoma kinase. Oncogene 2007; 26:859-869.
    • (2007) Oncogene , vol.26 , pp. 859-869
    • Kuo, A.H.1    Stoica, G.E.2    Riegel, A.T.3    Wellstein, A.4
  • 38
    • 84876800337 scopus 로고    scopus 로고
    • Macrophage biology in development, homeostasis and disease
    • Wynn TA, Chawla A, Pollard JW. Macrophage biology in development, homeostasis and disease. Nature 2013; 496:445-455.
    • (2013) Nature , vol.496 , pp. 445-455
    • Wynn, T.A.1    Chawla, A.2    Pollard, J.W.3
  • 39
    • 0043267732 scopus 로고    scopus 로고
    • Genetic regulation of osteoclast development and function
    • DOI 10.1038/nrg1122
    • Teitelbaum SL, Ross FP. Genetic regulation of osteoclast development and function. Nat Rev Genet 2003; 4:638-649. (Pubitemid 36917505)
    • (2003) Nature Reviews Genetics , vol.4 , Issue.8 , pp. 638-649
    • Teitelbaum, S.L.1    Ross, F.P.2
  • 41
    • 0035412388 scopus 로고    scopus 로고
    • Rescue of the colony-stimulating factor 1 (CSF-1)-nullizygous mouse (Csf1(op)/Csf1(op)) phenotype with a CSF-1 transgene and identification of sites of local CSF-1 synthesis
    • Ryan GR, Dai XM, Dominguez MG, et al. Rescue of the colony-stimulating factor 1 (CSF-1)-nullizygous mouse (Csf1(op)/Csf1(op)) phenotype with a CSF-1 transgene and identification of sites of local CSF-1 synthesis. Blood 2001; 98:74-84.
    • (2001) Blood , vol.98 , pp. 74-84
    • Ryan, G.R.1    Dai, X.M.2    Dominguez, M.G.3
  • 43
    • 0036092801 scopus 로고    scopus 로고
    • Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects
    • Dai XM, Ryan GR, Hapel AJ, et al. Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects. Blood 2002; 99:111-120.
    • (2002) Blood , vol.99 , pp. 111-120
    • Dai, X.M.1    Ryan, G.R.2    Hapel, A.J.3
  • 46
    • 0037113931 scopus 로고    scopus 로고
    • A RANK/TRAF6-dependent signal transduction pathway is essential for osteoclast cytoskeletal organization and resorptive function
    • DOI 10.1074/jbc.M202009200
    • Armstrong AP, Tometsko ME, Glaccum M, Sutherland CL, Cosman D, Dougall WC. A RANK/TRAF6-dependent signal transduction pathway is essential for osteoclast cytoskeletal organization and resorptive function. J Biol Chem 2002; 277:44347-44356. (Pubitemid 36157870)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.46 , pp. 44347-44356
    • Armstrong, A.P.1    Tometsko, M.E.2    Glaccum, M.3    Sutherland, C.L.4    Cosman, D.5    Dougall, W.C.6
  • 48
    • 0031570952 scopus 로고    scopus 로고
    • Dendritic Cell Subtypes in Mouse Lymphoid Organs: Cross-Correlation of Surface Markers, Changes with Incubation, and Differences among Thymus, Spleen, and Lymph Nodes
    • Vremec D, Shortman K. Dendritic cell subtypes in mouse lymphoid organs: cross-correlation of surface markers, changes with incubation, and differences among thymus, spleen, and lymph nodes. J Immunol 1997; 159:565-573. (Pubitemid 127484204)
    • (1997) Journal of Immunology , vol.159 , Issue.2 , pp. 565-573
    • Vremec, D.1    Shortman, K.2
  • 49
    • 0030728480 scopus 로고    scopus 로고
    • Dendritic cell development: Multiple pathways to nature's adjuvants
    • Shortman K, Caux C. Dendritic cell development: multiple pathways to nature's adjuvants. Stem Cells 1997; 15:409-419. (Pubitemid 27513715)
    • (1997) Stem Cells , vol.15 , Issue.6 , pp. 409-419
    • Shortman, K.1    Caux, C.2
  • 50
    • 0034653434 scopus 로고    scopus 로고
    • CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleen
    • Vremec D, Pooley J, Hochrein H, Wu L, Shortman K. CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleen. J Immunol 2000; 164:2978-2986. (Pubitemid 30148956)
    • (2000) Journal of Immunology , vol.164 , Issue.6 , pp. 2978-2986
    • Vremec, D.1    Pooley, J.2    Hochrein, H.3    Wu, L.4    Shortman, K.5
  • 52
    • 22544455619 scopus 로고    scopus 로고
    • The colony-stimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion
    • MacDonald KP, Rowe V, Bofinger HM, et al. The colonystimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion. J Immunol 2005; 175:1399-1405. (Pubitemid 41023039)
    • (2005) Journal of Immunology , vol.175 , Issue.3 , pp. 1399-1405
    • MacDonald, K.P.A.1    Rowe, V.2    Bofinger, H.M.3    Thomas, R.4    Sasmono, T.5    Hume, D.A.6    Hill, G.R.7
  • 53
    • 80355136629 scopus 로고    scopus 로고
    • Studying the mononuclear phagocyte system in the molecular age
    • Chow A, Brown BD, Merad M. Studying the mononuclear phagocyte system in the molecular age. Nat Rev Immunol 2011; 11:788-798.
    • (2011) Nat Rev Immunol , vol.11 , pp. 788-798
    • Chow, A.1    Brown, B.D.2    Merad, M.3
  • 54
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • DOI 10.1038/378785a0
    • Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995; 378:785-789. (Pubitemid 26004411)
    • (1995) Nature , vol.378 , Issue.6559 , pp. 785-789
    • Cross, D.A.E.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.