Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1- dependent ABL1 activation in endothelial cells

Journal of Experimental Medicine

Volumn 211, Issue 6, 2014, Pages 1167-1183

  Raimondi, Claudio ^a   Fantin, Alessandro ^a   Lampropoulou, Anastasia ^a   Denti, Laura ^a   Chikh, Anissa ^b   Ruhrberg, Christiana ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABELSON KINASE; ABL 1 PROTEIN; ACTIN; BCR ABL PROTEIN; FIBRONECTIN; IMATINIB; INTEGRIN; NEUROPILIN 1; PAXILLIN; UNCLASSIFIED DRUG; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC THERAPY; ARTICLE; CELL ADHESION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; ENDOTHELIUM CELL; FOCAL ADHESION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RETINA; SIGNAL TRANSDUCTION;

ANIMALS; BENZAMIDES; CELL ADHESION; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; FIBRONECTINS; HUMANS; IMMUNOBLOTTING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; NEOVASCULARIZATION, PHYSIOLOGIC; NEUROPILIN-1; PAXILLIN; PHOSPHORYLATION; PIPERAZINES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-ABL; PYRIMIDINES; RETINAL NEOVASCULARIZATION; RNA INTERFERENCE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84901760004     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20132330     Document Type: Article

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