메뉴 건너뛰기




Volumn 182, Issue 4, 2013, Pages 1379-1390

VEGF-A is necessary and sufficient for retinal neuroprotection in models of experimental glaucoma

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAUROSPORINE; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2;

EID: 84875185167     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.12.032     Document Type: Article
Times cited : (158)

References (55)
  • 2
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
    • S. Soker, S. Takashima, H.Q. Miao, G. Neufeld, and M. Klagsbrun Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor Cell 92 1998 735 745
    • (1998) Cell , vol.92 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3    Neufeld, G.4    Klagsbrun, M.5
  • 3
    • 0000481740 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Direct neuroprotective effect in in vitro ischemia
    • K.L. Jin, X.O. Mao, and D.A. Greenberg Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia Proc Natl Acad Sci U S A 97 2000 10242 10247
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 10242-10247
    • Jin, K.L.1    Mao, X.O.2    Greenberg, D.A.3
  • 4
    • 34948837854 scopus 로고    scopus 로고
    • The VEGFR2 and PKA pathways converge at MEK/ERK1/2 to promote survival in serum deprived neuronal cells
    • E. Gomes, L. Papa, T. Hao, and P. Rockwell The VEGFR2 and PKA pathways converge at MEK/ERK1/2 to promote survival in serum deprived neuronal cells Mol Cell Biochem 305 2007 179 190
    • (2007) Mol Cell Biochem , vol.305 , pp. 179-190
    • Gomes, E.1    Papa, L.2    Hao, T.3    Rockwell, P.4
  • 5
    • 42549127816 scopus 로고    scopus 로고
    • Vascular endothelial growth factor protects spinal cord motoneurons against glutamate-induced excitotoxicity via phosphatidylinositol 3-kinase
    • L. Tolosa, M. Mir, V.J. Asensio, G. Olmos, and J. Llado Vascular endothelial growth factor protects spinal cord motoneurons against glutamate-induced excitotoxicity via phosphatidylinositol 3-kinase J Neurochem 105 2008 1080 1090
    • (2008) J Neurochem , vol.105 , pp. 1080-1090
    • Tolosa, L.1    Mir, M.2    Asensio, V.J.3    Olmos, G.4    Llado, J.5
  • 6
    • 0033565417 scopus 로고    scopus 로고
    • Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system
    • M. Sondell, G. Lundborg, and M. Kanje Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system J Neurosci 19 1999 5731 5740
    • (1999) J Neurosci , vol.19 , pp. 5731-5740
    • Sondell, M.1    Lundborg, G.2    Kanje, M.3
  • 8
    • 33845242529 scopus 로고    scopus 로고
    • Human vascular endothelial growth factor protects axotomized retinal ganglion cells in vivo by activating ERK-1/2 and Akt pathways
    • U. Kilic, E. Kilic, A. Jarve, Z. Guo, A. Spudich, K. Bieber, U. Barzena, C.L. Bassetti, H.H. Marti, and D.M. Hermann Human vascular endothelial growth factor protects axotomized retinal ganglion cells in vivo by activating ERK-1/2 and Akt pathways J Neurosci 26 2006 12439 12446
    • (2006) J Neurosci , vol.26 , pp. 12439-12446
    • Kilic, U.1    Kilic, E.2    Jarve, A.3    Guo, Z.4    Spudich, A.5    Bieber, K.6    Barzena, U.7    Bassetti, C.L.8    Marti, H.H.9    Hermann, D.M.10
  • 11
    • 0041743159 scopus 로고    scopus 로고
    • VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia
    • Y. Sun, K. Jin, L. Xie, J. Childs, X.O. Mao, A. Logvinova, and D.A. Greenberg VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia J Clin Invest 111 2003 1843 1851
    • (2003) J Clin Invest , vol.111 , pp. 1843-1851
    • Sun, Y.1    Jin, K.2    Xie, L.3    Childs, J.4    Mao, X.O.5    Logvinova, A.6    Greenberg, D.A.7
  • 13
    • 77952296959 scopus 로고    scopus 로고
    • Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis
    • A. Brockington, P.R. Heath, H. Holden, P. Kasher, F.L. Bender, F. Claes, D. Lambrechts, M. Sendtner, P. Carmeliet, and P.J. Shaw Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis BMC Genomics 11 2010 203
    • (2010) BMC Genomics , vol.11 , pp. 203
    • Brockington, A.1    Heath, P.R.2    Holden, H.3    Kasher, P.4    Bender, F.L.5    Claes, F.6    Lambrechts, D.7    Sendtner, M.8    Carmeliet, P.9    Shaw, P.J.10
  • 14
    • 84860156429 scopus 로고    scopus 로고
    • Biological, preclinical and clinical characteristics of inhibitors of vascular endothelial growth factors
    • V. Chong Biological, preclinical and clinical characteristics of inhibitors of vascular endothelial growth factors Ophthalmologica 227 Suppl 1 2012 2 10
    • (2012) Ophthalmologica , vol.227 , Issue.SUPPL. 1 , pp. 2-10
    • Chong, V.1
  • 15
    • 20544455330 scopus 로고    scopus 로고
    • Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy
    • N. Ferrara, K.J. Hillan, and W. Novotny Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy Biochem Biophys Res Commun 333 2005 328 335
    • (2005) Biochem Biophys Res Commun , vol.333 , pp. 328-335
    • Ferrara, N.1    Hillan, K.J.2    Novotny, W.3
  • 17
    • 33746690523 scopus 로고    scopus 로고
    • Interleukin-6 protects retinal ganglion cells from pressure-induced death
    • R.M. Sappington, M. Chan, and D.J. Calkins Interleukin-6 protects retinal ganglion cells from pressure-induced death Invest Ophthalmol Vis Sci 47 2006 2932 2942
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 2932-2942
    • Sappington, R.M.1    Chan, M.2    Calkins, D.J.3
  • 18
    • 70450224235 scopus 로고    scopus 로고
    • Cyan fluorescent protein (CFP) expressing cells in the retina of Thy1-CFP transgenic mice before and after optic nerve injury
    • X. Wang, M.L. Archibald, K. Stevens, W.H. Baldridge, and B.C. Chauhan Cyan fluorescent protein (CFP) expressing cells in the retina of Thy1-CFP transgenic mice before and after optic nerve injury Neurosci Lett 468 2010 110 114
    • (2010) Neurosci Lett , vol.468 , pp. 110-114
    • Wang, X.1    Archibald, M.L.2    Stevens, K.3    Baldridge, W.H.4    Chauhan, B.C.5
  • 19
    • 6944234914 scopus 로고    scopus 로고
    • Caspase-independent component of retinal ganglion cell death, in vitro
    • G. Tezel, and X. Yang Caspase-independent component of retinal ganglion cell death, in vitro Invest Ophthalmol Vis Sci 45 2004 4049 4059
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 4049-4059
    • Tezel, G.1    Yang, X.2
  • 22
    • 0035344017 scopus 로고    scopus 로고
    • Vascular endothelial growth factor rescues hippocampal neurons from glutamate-induced toxicity: Signal transduction cascades
    • H. Matsuzaki, M. Tamatani, A. Yamaguchi, K. Namikawa, H. Kiyama, M.P. Vitek, N. Mitsuda, and M. Tohyama Vascular endothelial growth factor rescues hippocampal neurons from glutamate-induced toxicity: signal transduction cascades FASEB J 15 2001 1218 1220
    • (2001) FASEB J , vol.15 , pp. 1218-1220
    • Matsuzaki, H.1    Tamatani, M.2    Yamaguchi, A.3    Namikawa, K.4    Kiyama, H.5    Vitek, M.P.6    Mitsuda, N.7    Tohyama, M.8
  • 23
    • 33644851946 scopus 로고    scopus 로고
    • Assessment of neuroprotective effects of glutamate modulation on glaucoma-related retinal ganglion cell apoptosis in vivo
    • L. Guo, T.E. Salt, A. Maass, V. Luong, S.E. Moss, F.W. Fitzke, and M.F. Cordeiro Assessment of neuroprotective effects of glutamate modulation on glaucoma-related retinal ganglion cell apoptosis in vivo Invest Ophthalmol Vis Sci 47 2006 626 633
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 626-633
    • Guo, L.1    Salt, T.E.2    Maass, A.3    Luong, V.4    Moss, S.E.5    Fitzke, F.W.6    Cordeiro, M.F.7
  • 24
    • 0033823857 scopus 로고    scopus 로고
    • Differential susceptibility of retinal ganglion cells to reactive oxygen species
    • K. Kortuem, L.K. Geiger, and L.A. Levin Differential susceptibility of retinal ganglion cells to reactive oxygen species Invest Ophthalmol Vis Sci 41 2000 3176 3182
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 3176-3182
    • Kortuem, K.1    Geiger, L.K.2    Levin, L.A.3
  • 25
    • 64549158079 scopus 로고    scopus 로고
    • Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress
    • X. Wang, A. Zaidi, R. Pal, A.S. Garrett, R. Braceras, X.W. Chen, M.L. Michaelis, and E.K. Michaelis Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress BMC Neurosci 10 2009 12
    • (2009) BMC Neurosci , vol.10 , pp. 12
    • Wang, X.1    Zaidi, A.2    Pal, R.3    Garrett, A.S.4    Braceras, R.5    Chen, X.W.6    Michaelis, M.L.7    Michaelis, E.K.8
  • 26
    • 24644438306 scopus 로고    scopus 로고
    • Retinal-cell-conditioned medium prevents TNF-alpha-induced apoptosis of purified ganglion cells
    • C. Fuchs, V. Forster, E. Balse, J.A. Sahel, S. Picaud, and L.H. Tessier Retinal-cell-conditioned medium prevents TNF-alpha-induced apoptosis of purified ganglion cells Invest Ophthalmol Vis Sci 46 2005 2983 2991
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 2983-2991
    • Fuchs, C.1    Forster, V.2    Balse, E.3    Sahel, J.A.4    Picaud, S.5    Tessier, L.H.6
  • 27
    • 33947285383 scopus 로고    scopus 로고
    • NMDA-induced interleukin-1beta expression is mediated by nuclear factor-kappa B p65 in the retina
    • Y. Kitaoka, Y. Munemasa, T. Nakazawa, and S. Ueno NMDA-induced interleukin-1beta expression is mediated by nuclear factor-kappa B p65 in the retina Brain Res 1142 2007 247 255
    • (2007) Brain Res , vol.1142 , pp. 247-255
    • Kitaoka, Y.1    Munemasa, Y.2    Nakazawa, T.3    Ueno, S.4
  • 28
    • 25144446151 scopus 로고    scopus 로고
    • Retinal ganglion cell death is delayed by activation of retinal intrinsic cell survival program
    • H.S. Kim, and C.K. Park Retinal ganglion cell death is delayed by activation of retinal intrinsic cell survival program Brain Res 1057 2005 17 28
    • (2005) Brain Res , vol.1057 , pp. 17-28
    • Kim, H.S.1    Park, C.K.2
  • 30
    • 0037308354 scopus 로고    scopus 로고
    • Caspase activation pathways induced by staurosporine and low potassium: Role of caspase-2
    • A. Caballero-Benitez, and J. Moran Caspase activation pathways induced by staurosporine and low potassium: role of caspase-2 J Neurosci Res 71 2003 383 396
    • (2003) J Neurosci Res , vol.71 , pp. 383-396
    • Caballero-Benitez, A.1    Moran, J.2
  • 31
    • 84858841220 scopus 로고    scopus 로고
    • Diverse roles for VEGF-A in the nervous system
    • F. Mackenzie, and C. Ruhrberg Diverse roles for VEGF-A in the nervous system Development 139 2012 1371 1380
    • (2012) Development , vol.139 , pp. 1371-1380
    • Mackenzie, F.1    Ruhrberg, C.2
  • 32
    • 0141621049 scopus 로고    scopus 로고
    • Viral vascular endothelial growth factors vary extensively in amino acid sequence, receptor-binding specificities, and the ability to induce vascular permeability yet are uniformly active mitogens
    • L.M. Wise, N. Ueda, N.H. Dryden, S.B. Fleming, C. Caesar, S. Roufail, M.G. Achen, S.A. Stacker, and A.A. Mercer Viral vascular endothelial growth factors vary extensively in amino acid sequence, receptor-binding specificities, and the ability to induce vascular permeability yet are uniformly active mitogens J Biol Chem 278 2003 38004 38014
    • (2003) J Biol Chem , vol.278 , pp. 38004-38014
    • Wise, L.M.1    Ueda, N.2    Dryden, N.H.3    Fleming, S.B.4    Caesar, C.5    Roufail, S.6    Achen, M.G.7    Stacker, S.A.8    Mercer, A.A.9
  • 34
    • 0026409550 scopus 로고
    • Relationship between intraocular pressure and primary open angle glaucoma among white and black Americans: The Baltimore Eye Survey
    • A. Sommer, J.M. Tielsch, J. Katz, H.A. Quigley, J.D. Gottsch, J. Javitt, and K. Singh Relationship between intraocular pressure and primary open angle glaucoma among white and black Americans: the Baltimore Eye Survey Arch Ophthalmol 109 1991 1090 1095
    • (1991) Arch Ophthalmol , vol.109 , pp. 1090-1095
    • Sommer, A.1    Tielsch, J.M.2    Katz, J.3    Quigley, H.A.4    Gottsch, J.D.5    Javitt, J.6    Singh, K.7
  • 35
    • 0032461801 scopus 로고    scopus 로고
    • Clinical and ocular histopathological findings in a patient with normal-pressure glaucoma
    • M.B. Wax, G. Tezel, and P.D. Edward Clinical and ocular histopathological findings in a patient with normal-pressure glaucoma Arch Ophthalmol 116 1998 993 1001
    • (1998) Arch Ophthalmol , vol.116 , pp. 993-1001
    • Wax, M.B.1    Tezel, G.2    Edward, P.D.3
  • 37
    • 0029069797 scopus 로고
    • Programmed cell death of retinal ganglion cells during experimental glaucoma
    • E. Garcia-Valenzuela, S. Shareef, J. Walsh, and S.C. Sharma Programmed cell death of retinal ganglion cells during experimental glaucoma Exp Eye Res 61 1995 33 44
    • (1995) Exp Eye Res , vol.61 , pp. 33-44
    • Garcia-Valenzuela, E.1    Shareef, S.2    Walsh, J.3    Sharma, S.C.4
  • 40
    • 27544480984 scopus 로고    scopus 로고
    • Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice
    • T.C. Jakobs, R.T. Libby, Y. Ben, S.W. John, and R.H. Masland Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice J Cell Biol 171 2005 313 325
    • (2005) J Cell Biol , vol.171 , pp. 313-325
    • Jakobs, T.C.1    Libby, R.T.2    Ben, Y.3    John, S.W.4    Masland, R.H.5
  • 41
    • 0032515047 scopus 로고    scopus 로고
    • Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway: Requirement for Flk-1/KDR activation
    • H.P. Gerber, A. McMurtrey, J. Kowalski, M. Yan, B.A. Keyt, V. Dixit, and N. Ferrara Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway: requirement for Flk-1/KDR activation J Biol Chem 273 1998 30336 30343
    • (1998) J Biol Chem , vol.273 , pp. 30336-30343
    • Gerber, H.P.1    McMurtrey, A.2    Kowalski, J.3    Yan, M.4    Keyt, B.A.5    Dixit, V.6    Ferrara, N.7
  • 43
    • 34547671040 scopus 로고    scopus 로고
    • Vascular endothelial cell growth factor-A: Not just for endothelial cells anymore
    • P.A. D'Amore Vascular endothelial cell growth factor-A: not just for endothelial cells anymore Am J Pathol 171 2007 14 18
    • (2007) Am J Pathol , vol.171 , pp. 14-18
    • D'Amore, P.A.1
  • 44
    • 0035842544 scopus 로고    scopus 로고
    • Caspase-3 and the regulation of hypoxic neuronal death by vascular endothelial growth factor
    • K. Jin, X.O. Mao, S.P. Batteur, E. McEachron, A. Leahy, and D.A. Greenberg Caspase-3 and the regulation of hypoxic neuronal death by vascular endothelial growth factor Neuroscience 108 2001 351 358
    • (2001) Neuroscience , vol.108 , pp. 351-358
    • Jin, K.1    Mao, X.O.2    Batteur, S.P.3    McEachron, E.4    Leahy, A.5    Greenberg, D.A.6
  • 45
    • 79956272964 scopus 로고    scopus 로고
    • Preventing HO-induced apoptosis in cerebellar granule neurons by regulating the VEGFR-2/Akt signaling pathway using a novel dimeric antiacetylcholinesterase bis(12)-hupyridone
    • W. Cui, W. Li, Y. Zhao, S. Mak, Y. Gao, J. Luo, H. Zhang, Y. Liu, P.R. Carlier, J. Rong, and Y. Han Preventing HO-induced apoptosis in cerebellar granule neurons by regulating the VEGFR-2/Akt signaling pathway using a novel dimeric antiacetylcholinesterase bis(12)-hupyridone Brain Res 1394 2011 14 23
    • (2011) Brain Res , vol.1394 , pp. 14-23
    • Cui, W.1    Li, W.2    Zhao, Y.3    Mak, S.4    Gao, Y.5    Luo, J.6    Zhang, H.7    Liu, Y.8    Carlier, P.R.9    Rong, J.10    Han, Y.11
  • 46
    • 22444447946 scopus 로고    scopus 로고
    • Common mechanisms of nerve and blood vessel wiring
    • P. Carmeliet, and M. Tessier-Lavigne Common mechanisms of nerve and blood vessel wiring Nature 436 2005 193 200
    • (2005) Nature , vol.436 , pp. 193-200
    • Carmeliet, P.1    Tessier-Lavigne, M.2
  • 47
    • 82755193685 scopus 로고    scopus 로고
    • VEGF protects rat cortical neurons from mechanical trauma injury induced apoptosis via the MEK/ERK pathway
    • Y. Ma, W. Liu, Y. Wang, X. Chao, Y. Qu, K. Wang, and Z. Fei VEGF protects rat cortical neurons from mechanical trauma injury induced apoptosis via the MEK/ERK pathway Brain Res Bull 86 2011 441 446
    • (2011) Brain Res Bull , vol.86 , pp. 441-446
    • Ma, Y.1    Liu, W.2    Wang, Y.3    Chao, X.4    Qu, Y.5    Wang, K.6    Fei, Z.7
  • 48
    • 33947358942 scopus 로고    scopus 로고
    • Therapeutic potential of phosphatidylinositol 3-kinase inhibitors in inflammatory respiratory disease
    • K. Ito, G. Caramori, and I.M. Adcock Therapeutic potential of phosphatidylinositol 3-kinase inhibitors in inflammatory respiratory disease J Pharmacol Exp Ther 321 2007 1 8
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 1-8
    • Ito, K.1    Caramori, G.2    Adcock, I.M.3
  • 49
    • 84863752684 scopus 로고    scopus 로고
    • Clinical and electrophysiologic outcome in patients with neovascular glaucoma treated with and without bevacizumab
    • E. Wittström, H. Holmberg, C. Hvarfner, and S. Andréasson Clinical and electrophysiologic outcome in patients with neovascular glaucoma treated with and without bevacizumab Eur J Ophthalmol 22 2012 563 574
    • (2012) Eur J Ophthalmol , vol.22 , pp. 563-574
    • Wittström, E.1    Holmberg, H.2    Hvarfner, C.3    Andréasson, S.4
  • 53
    • 77956267091 scopus 로고    scopus 로고
    • Visual dysfunction associated with diabetic retinopathy
    • G.R. Jackson, and A.J. Barber Visual dysfunction associated with diabetic retinopathy Curr Diab Rep 10 2010 380 384
    • (2010) Curr Diab Rep , vol.10 , pp. 380-384
    • Jackson, G.R.1    Barber, A.J.2
  • 55
    • 84875176558 scopus 로고    scopus 로고
    • Year 7 outcomes for ranibizumab-treated subjects in anchor/marina: A multicenter, prospective cohort study
    • R.B. Bhisitkul, S. Rofagha, D.S. Boyer, S. Sadda, and K. Zhang Year 7 outcomes for ranibizumab-treated subjects in anchor/marina: a multicenter, prospective cohort study ARVO Meeting Abstracts 53 2012 3679
    • (2012) ARVO Meeting Abstracts , vol.53 , pp. 3679
    • Bhisitkul, R.B.1    Rofagha, S.2    Boyer, D.S.3    Sadda, S.4    Zhang, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.