메뉴 건너뛰기




Volumn 10, Issue 2, 2014, Pages

Chromosome X-Wide Association Study Identifies Loci for Fasting Insulin and Height and Evidence for Incomplete Dosage Compensation

(17)  Tukiainen, Taru a,b,c   Pirinen, Matti a   Sarin, Antti Pekka a,d   Ladenvall, Claes e   Kettunen, Johannes a,d   Lehtimäki, Terho f   Lokki, Marja Liisa g   Perola, Markus a,d,h   Sinisalo, Juha i   Vlachopoulou, Efthymia g   Eriksson, Johan G a,d,i,j,k   Groop, Leif a,e   Jula, Antti d   Järvelin, Marjo Riitta d,l,m,n   Raitakari, Olli T o,p   Salomaa, Veikko d   Ripatti, Samuli a,d,q  


Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; ATRX PROTEIN, HUMAN; CATION TRANSPORT PROTEIN; DNA HELICASE; FGF16 PROTEIN, HUMAN; FIBROBLAST GROWTH FACTOR; ITM2A PROTEIN, HUMAN; MAGT1 PROTEIN, HUMAN; MEMBRANE PROTEIN; NUCLEAR PROTEIN;

EID: 84901743386     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004127     Document Type: Article
Times cited : (57)

References (37)
  • 2
    • 79957588287 scopus 로고    scopus 로고
    • Genome partitioning of genetic variation for complex traits using common SNPs
    • Yang J, Manolio TA, Pasquale LR, Boerwinkle E, Caporaso N, et al. (2011) Genome partitioning of genetic variation for complex traits using common SNPs. Nat Genet 43: 519-525.
    • (2011) Nat Genet , vol.43 , pp. 519-525
    • Yang, J.1    Manolio, T.A.2    Pasquale, L.R.3    Boerwinkle, E.4    Caporaso, N.5
  • 3
    • 84877306707 scopus 로고    scopus 로고
    • eXclusion: Toward Integrating the X Chromosome in Genome-wide Association Analyses
    • Wise AL, Gyi L, Manolio TA, (2013) eXclusion: Toward Integrating the X Chromosome in Genome-wide Association Analyses. Am J Hum Genet 92: 643-647.
    • (2013) Am J Hum Genet , vol.92 , pp. 643-647
    • Wise, A.L.1    Gyi, L.2    Manolio, T.A.3
  • 4
    • 84864619335 scopus 로고    scopus 로고
    • A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation
    • Coviello AD, Haring R, Wellons M, Vaidya D, Lehtimaki T, et al. (2012) A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet 8: e1002805.
    • (2012) PLoS Genet , vol.8
    • Coviello, A.D.1    Haring, R.2    Wellons, M.3    Vaidya, D.4    Lehtimaki, T.5
  • 5
    • 84883199435 scopus 로고    scopus 로고
    • An X chromosome-wide association analysis identifies variants in GPR174 as a risk factor for Graves' disease
    • Chu X, Shen M, Xie F, Miao XJ, Shou WH, et al. (2013) An X chromosome-wide association analysis identifies variants in GPR174 as a risk factor for Graves' disease. J Med Genet 50: 479-485.
    • (2013) J Med Genet , vol.50 , pp. 479-485
    • Chu, X.1    Shen, M.2    Xie, F.3    Miao, X.J.4    Shou, W.H.5
  • 6
    • 78049349396 scopus 로고    scopus 로고
    • Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
    • Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, et al. (2010) Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 42: 949-960.
    • (2010) Nat Genet , vol.42 , pp. 949-960
    • Heid, I.M.1    Jackson, A.U.2    Randall, J.C.3    Winkler, T.W.4    Qi, L.5
  • 7
  • 8
    • 15244353967 scopus 로고    scopus 로고
    • X-inactivation profile reveals extensive variability in X-linked gene expression in females
    • Carrel L, Willard HF, (2005) X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature 434: 400-404.
    • (2005) Nature , vol.434 , pp. 400-404
    • Carrel, L.1    Willard, H.F.2
  • 9
    • 84975795680 scopus 로고    scopus 로고
    • An integrated map of genetic variation from 1,092 human genomes
    • Genomes Project C
    • Genomes Project C (2012) Abecasis GR, Auton A, Brooks LD, DePristo MA, et al. (2012) An integrated map of genetic variation from 1,092 human genomes. Nature 491: 56-65.
    • (2012) Nature , vol.491 , pp. 56-65
    • Abecasis, G.R.1    Auton, A.2    Brooks, L.D.3    DePristo, M.A.4
  • 11
    • 77953808087 scopus 로고    scopus 로고
    • Genotype imputation for genome-wide association studies
    • Marchini J, Howie B, (2010) Genotype imputation for genome-wide association studies. Nat Rev Genet 11: 499-511.
    • (2010) Nat Rev Genet , vol.11 , pp. 499-511
    • Marchini, J.1    Howie, B.2
  • 12
    • 78649505227 scopus 로고    scopus 로고
    • Meta-analysis of sex-specific genome-wide association studies
    • Magi R, Lindgren CM, Morris AP, (2010) Meta-analysis of sex-specific genome-wide association studies. Genet Epidemiol 34: 846-853.
    • (2010) Genet Epidemiol , vol.34 , pp. 846-853
    • Magi, R.1    Lindgren, C.M.2    Morris, A.P.3
  • 13
    • 0034097948 scopus 로고    scopus 로고
    • Collagenase-3 (MMP-13) and integral membrane protein 2a (Itm2a) are marker genes of chondrogenic/osteoblastic cells in bone formation: sequential temporal, and spatial expression of Itm2a, alkaline phosphatase, MMP-13, and osteocalcin in the mouse
    • Tuckermann JP, Pittois K, Partridge NC, Merregaert J, Angel P, (2000) Collagenase-3 (MMP-13) and integral membrane protein 2a (Itm2a) are marker genes of chondrogenic/osteoblastic cells in bone formation: sequential temporal, and spatial expression of Itm2a, alkaline phosphatase, MMP-13, and osteocalcin in the mouse. J Bone Miner Res 15: 1257-1265.
    • (2000) J Bone Miner Res , vol.15 , pp. 1257-1265
    • Tuckermann, J.P.1    Pittois, K.2    Partridge, N.C.3    Merregaert, J.4    Angel, P.5
  • 14
    • 4344605197 scopus 로고    scopus 로고
    • In vitro studies on Itm2a reveal its involvement in early stages of the chondrogenic differentiation pathway
    • Van den Plas D, Merregaert J, (2004) In vitro studies on Itm2a reveal its involvement in early stages of the chondrogenic differentiation pathway. Biol Cell 96: 463-470.
    • (2004) Biol Cell , vol.96 , pp. 463-470
    • Van den Plas, D.1    Merregaert, J.2
  • 15
    • 33847398443 scopus 로고    scopus 로고
    • Alpha thalassaemia-mental retardation, X linked
    • Gibbons R, (2006) Alpha thalassaemia-mental retardation, X linked. Orphanet J Rare Dis 1: 15.
    • (2006) Orphanet J Rare Dis , vol.1 , pp. 15
    • Gibbons, R.1
  • 16
    • 84878485201 scopus 로고    scopus 로고
    • Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations
    • Band G, Le Q, Jostins L, Pirinen M, Kivinen K, et al. (2013) Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations. PLoS Genet 9: e1003509.
    • (2013) PLoS Genet , vol.9
    • Band, G.1    Le, Q.2    Jostins, L.3    Pirinen, M.4    Kivinen, K.5
  • 17
    • 80055080761 scopus 로고    scopus 로고
    • Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry
    • N'Diaye A, Chen GK, Palmer CD, Ge B, Tayo B, et al. (2011) Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. PLoS Genet 7: e1002298.
    • (2011) PLoS Genet , vol.7
    • N'Diaye, A.1    Chen, G.K.2    Palmer, C.D.3    Ge, B.4    Tayo, B.5
  • 18
    • 84856117436 scopus 로고    scopus 로고
    • Genome-wide association study of body height in African Americans: the Women's Health Initiative SNP Health Association Resource (SHARe)
    • Carty CL, Johnson NA, Hutter CM, Reiner AP, Peters U, et al. (2012) Genome-wide association study of body height in African Americans: the Women's Health Initiative SNP Health Association Resource (SHARe). Hum Mol Genet 21: 711-720.
    • (2012) Hum Mol Genet , vol.21 , pp. 711-720
    • Carty, C.L.1    Johnson, N.A.2    Hutter, C.M.3    Reiner, A.P.4    Peters, U.5
  • 21
    • 84883149881 scopus 로고    scopus 로고
    • Whole exome sequencing identifies FGF16 nonsense mutations as the cause of X-linked recessive metacarpal 4/5 fusion
    • Jamsheer A, Zemojtel T, Kolanczyk M, Stricker S, Hecht J, et al. (2013) Whole exome sequencing identifies FGF16 nonsense mutations as the cause of X-linked recessive metacarpal 4/5 fusion. J Med Genet 50: 579-584.
    • (2013) J Med Genet , vol.50 , pp. 579-584
    • Jamsheer, A.1    Zemojtel, T.2    Kolanczyk, M.3    Stricker, S.4    Hecht, J.5
  • 22
    • 69949165799 scopus 로고    scopus 로고
    • Enhanced ITM2A expression inhibits chondrogenic differentiation of mesenchymal stem cells
    • Boeuf S, Borger M, Hennig T, Winter A, Kasten P, et al. (2009) Enhanced ITM2A expression inhibits chondrogenic differentiation of mesenchymal stem cells. Differentiation 78: 108-115.
    • (2009) Differentiation , vol.78 , pp. 108-115
    • Boeuf, S.1    Borger, M.2    Hennig, T.3    Winter, A.4    Kasten, P.5
  • 23
    • 84879677633 scopus 로고    scopus 로고
    • Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits
    • Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, et al. (2013) Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet 9: e1003500.
    • (2013) PLoS Genet , vol.9
    • Randall, J.C.1    Winkler, T.W.2    Kutalik, Z.3    Berndt, S.I.4    Jackson, A.U.5
  • 24
    • 80055065043 scopus 로고    scopus 로고
    • Influence of sex and genetic variability on expression of X-linked genes in human monocytes
    • Castagne R, Zeller T, Rotival M, Szymczak S, Truong V, et al. (2011) Influence of sex and genetic variability on expression of X-linked genes in human monocytes. Genomics 98: 320-326.
    • (2011) Genomics , vol.98 , pp. 320-326
    • Castagne, R.1    Zeller, T.2    Rotival, M.3    Szymczak, S.4    Truong, V.5
  • 25
    • 77951758776 scopus 로고    scopus 로고
    • Increased number of sex chromosomes affects height in a nonlinear fashion: a study of 305 patients with sex chromosome aneuploidy
    • Ottesen AM, Aksglaede L, Garn I, Tartaglia N, Tassone F, et al. (2010) Increased number of sex chromosomes affects height in a nonlinear fashion: a study of 305 patients with sex chromosome aneuploidy. Am J Med Genet A 152A: 1206-1212.
    • (2010) Am J Med Genet A , vol.152 A , pp. 1206-1212
    • Ottesen, A.M.1    Aksglaede, L.2    Garn, I.3    Tartaglia, N.4    Tassone, F.5
  • 26
    • 0014655989 scopus 로고
    • Groups at risk in low birth weight infants and perinatal mortality
    • Rantakallio P, (1969) Groups at risk in low birth weight infants and perinatal mortality. Acta Paediatr Scand 193 (Suppl 193) ():: 191.
    • (1969) Acta Paediatr Scand , vol.193 , Issue.SUPPL. 193 , pp. 191
    • Rantakallio, P.1
  • 29
    • 34249888775 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
    • Diabetes Genetics Initiative of Broad Institute of H, Mit LU, Novartis Institutes of BioMedical R
    • Diabetes Genetics Initiative of Broad Institute of H, Mit LU, Novartis Institutes of BioMedical R (2007) Saxena R, Voight BF, et al. (2007) Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316: 1331-1336.
    • (2007) Science , vol.316 , pp. 1331-1336
    • Saxena, R.1    Voight, B.F.2
  • 30
    • 70349263990 scopus 로고    scopus 로고
    • OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism
    • Perttila J, Merikanto K, Naukkarinen J, Surakka I, Martin NW, et al. (2009) OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism. J Mol Med (Berl) 87: 825-835.
    • (2009) J Mol Med (Berl) , vol.87 , pp. 825-835
    • Perttila, J.1    Merikanto, K.2    Naukkarinen, J.3    Surakka, I.4    Martin, N.W.5
  • 32
    • 84857648463 scopus 로고    scopus 로고
    • Genome-wide association study identifies multiple loci influencing human serum metabolite levels
    • Kettunen J, Tukiainen T, Sarin AP, Ortega-Alonso A, Tikkanen E, et al. (2012) Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Nat Genet 44: 269-276.
    • (2012) Nat Genet , vol.44 , pp. 269-276
    • Kettunen, J.1    Tukiainen, T.2    Sarin, A.P.3    Ortega-Alonso, A.4    Tikkanen, E.5
  • 33
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • Howie BN, Donnelly P, Marchini J, (2009) A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet 5: e1000529.
    • (2009) PLoS Genet , vol.5
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 34
    • 84863845193 scopus 로고    scopus 로고
    • Genotype imputation with thousands of genomes
    • Howie B, Marchini J, Stephens M, (2011) Genotype imputation with thousands of genomes. G3 (Bethesda) 1: 457-470.
    • (2011) G3 (Bethesda) , vol.1 , pp. 457-470
    • Howie, B.1    Marchini, J.2    Stephens, M.3
  • 35
    • 77950301214 scopus 로고    scopus 로고
    • Variance component model to account for sample structure in genome-wide association studies
    • Kang HM, Sul JH, Service SK, Zaitlen NA, Kong SY, et al. (2010) Variance component model to account for sample structure in genome-wide association studies. Nat Genet 42: 348-354.
    • (2010) Nat Genet , vol.42 , pp. 348-354
    • Kang, H.M.1    Sul, J.H.2    Service, S.K.3    Zaitlen, N.A.4    Kong, S.Y.5
  • 37
    • 84863393715 scopus 로고    scopus 로고
    • Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke
    • International Stroke Genetics C, Wellcome Trust Case Control C
    • International Stroke Genetics C, Wellcome Trust Case Control C (2012) Bellenguez C, Bevan S, Gschwendtner A, et al. (2012) Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet 44: 328-333.
    • (2012) Nat Genet , vol.44 , pp. 328-333
    • Bellenguez, C.1    Bevan, S.2    Gschwendtner, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.