In vivo imaging of specific drug-target binding at subcellular resolution

Nature Communications

Volumn 5, Issue , 2014, Pages

  Dubach, J M ^a   Vinegoni, C ^a   Mazitschek, R ^a   Fumene Feruglio, P ^a   Cameron, L A ^b   Weissleder, R ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OLAPARIB; DRUG;

DRUG; ENZYME ACTIVITY; EXPERIMENTAL STUDY; IMAGING METHOD; LYSIS; MAPPING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANISOTROPY; ARTICLE; DRUG ACTIVITY; DRUG BINDING; DRUG DISTRIBUTION; DRUG LABELING; DRUG MECHANISM; DRUG TARGETING; FEMALE; IMAGING; IN VIVO STUDY; INTRACELLULAR MEMBRANE; LYSIS; MOLECULAR SIZE; MOUSE; MULTIPHOTON MICROSCOPY; NONHUMAN; QUANTUM YIELD; TEMPERATURE; VISCOSITY; ANIMAL; CELL FRACTIONATION; COMPUTER SYSTEM; DRUG DELIVERY SYSTEM; FLUORESCENCE POLARIZATION; HUMAN; METABOLISM; MOLECULAR IMAGING; NUDE MOUSE; PROCEDURES; TIME; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; COMPUTER SYSTEMS; DRUG DELIVERY SYSTEMS; FEMALE; FLUORESCENCE POLARIZATION; HUMANS; MICE, NUDE; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; MOLECULAR IMAGING; PHARMACEUTICAL PREPARATIONS; SUBCELLULAR FRACTIONS; TIME FACTORS;

EID: 84901706145     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4946     Document Type: Article

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