Structural and functional prevention of hypoxia-induced pulmonary hypertension by individualized exercise training in mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 306, Issue 11, 2014, Pages

  Weissmann, Norbert ^a   Peters, Dorothea M ^a   Klöpping, Christina ^a   Krüger, Karsten ^b   Pilat, Christian ^b   Katta, Susmitha ^a   Seimetz, Michael ^a   Ghofrani, Hossein A ^a   Schermuly, Ralph T ^a   Witzenrath, Martin ^c   Seeger, Werner ^a,d   Grimminger, Friedrich ^a   Mooren, Frank C ^b  

^a JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

Chronic hypoxia; Maximal walking distance; Pulmonary vascular remodeling; Sildenafil; Training

Indexed keywords

GUANYLATE CYCLASE; PHOSPHODIESTERASE; SILDENAFIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EXERCISE; HEART HYPERTROPHY; HYPOXIA; LUNG BLOOD VESSEL; LUNG VASCULAR RESISTANCE; MALE; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SYSTOLIC BLOOD PRESSURE; TELEMETRY; WALKING;

CHRONIC HYPOXIA; MAXIMAL WALKING DISTANCE; PULMONARY VASCULAR REMODELING; SILDENAFIL; TRAINING;

3',5'-CYCLIC-AMP PHOSPHODIESTERASES; ANIMALS; ANOXIA; EXERCISE THERAPY; EXERCISE TOLERANCE; GENE EXPRESSION; HYPERTENSION, PULMONARY; LUNG; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE SYNTHASE; OXYGEN CONSUMPTION; PHOSPHODIESTERASE 5 INHIBITORS; PHYSICAL CONDITIONING, ANIMAL; PIPERAZINES; PURINES; SIGNAL TRANSDUCTION; SULFONES; VENTRICULAR PRESSURE;

EID: 84901701875     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00275.2013     Document Type: Article

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